The 129 codon polymorphism of the Prion Protein gene influences earlier cognitive performance in Down syndrome subjects

Journal of Neurology

Volumn 250, Issue 6, 2003, Pages 688-692

  Del Bo, Roberto ^a   Comi, Giacomo Pietro ^a,c   Giorda, Roberto ^b   Crimi, Marco ^a   Locatelli, Federica ^a   Martinelli Boneschi, Filippo ^a   Pozzoli, Uberto ^b   Castelli, Enrico ^b   Bresolin, Nereo ^a,b,c   Scarlato, Guglielmo ^a,c  

^a FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^b SCIENTIFIC INSTITUTE   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

Author keywords

Alzheimer's disease; Apolipoprotein E; Down syndrome; Mental retardation; Prion protein

Indexed keywords

APOLIPOPROTEIN E; METHIONINE; PRION PROTEIN; VALINE;

ADOLESCENT; ADULT; ALLELE; ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; ARTICLE; BRAIN DISEASE; CHILD; CODON; COGNITION; DOWN SYNDROME; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; HUMAN; INTELLECTUAL IMPAIRMENT; MAJOR CLINICAL STUDY; MALE; MENTAL DEFICIENCY; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AGE FACTORS; ALLELES; AMINO ACID SUBSTITUTION; APOLIPOPROTEIN E4; APOLIPOPROTEINS E; CHILD; CHILD, PRESCHOOL; CODON; COGNITION DISORDERS; DOWN SYNDROME; FEMALE; FOLLOW-UP STUDIES; GENE FREQUENCY; GENOTYPE; HUMANS; INTELLIGENCE TESTS; MALE; METHIONINE; MUTATION; POLYMORPHISM, GENETIC; PRIONS; VALINE;

EID: 0038796590     PISSN: 03405354     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00415-003-1057-5     Document Type: Article

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