Microglia induce neurotoxicity via intraneuronal Zn2+ release and a K+ current surge

GLIA

Volumn 56, Issue 1, 2008, Pages 89-96

  Knoch, Megan E ^a   Hartnett, Karen A ^a   Hara, Hirokazu ^b   Kandler, Karl ^a   Aizenman, Elias ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

Author keywords

Apoptosis signaling kinase 1; Kv2.1; Nitration; Oxidation; Potassium channel; Zinc

Indexed keywords

5,10,15,20 TETRAKIS(4 SULFONATOPHENYL)PORPHYRINATO IRON CHLORIDE; APOCYNIN; APOPTOSIS SIGNAL REGULATING KINASE 1; CATALASE; METALLOTHIONEIN III; MITOGEN ACTIVATED PROTEIN KINASE; PORPHYRIN DERIVATIVE; POTASSIUM ION; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SCAVENGER; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; ZINC ION;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CELL CULTURE; EMBRYO; GENE OVEREXPRESSION; MICROGLIA; NEUROTOXICITY; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; RAT; SPRAGUE DAWLEY RAT;

ANIMALS; CELL DEATH; CEREBRAL CORTEX; COCULTURE TECHNIQUES; ELECTROPHYSIOLOGY; FEMALE; IMMUNOHISTOCHEMISTRY; ION CHANNEL GATING; ION CHANNELS; LUCIFERASES; MAP KINASE KINASE KINASE 5; MICROGLIA; NEURODEGENERATIVE DISEASES; NEURONS; POTASSIUM CHANNELS; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; SHAB POTASSIUM CHANNELS; SIGNAL TRANSDUCTION; TRANSFECTION; ZINC;

EID: 36448987500     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20592     Document Type: Article

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