Induction of neuronal apoptosis by thiol oxidation: Putative role of intracellular zinc release

Journal of Neurochemistry

Volumn 75, Issue 5, 2000, Pages 1878-1888

  Aizenman, Elias ^a   Stout, Amy K ^a,b   Hartnett, Karen A ^a,c   Dineley, Kirk E ^a   McLaughlin, BethAnn ^a   Reynolds, Ian J ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b Migenix Inc   (United States)

^c Beckim Industries   (United States)

Author keywords

Apoptosis; Cerebral cortex; Oxidation; Tissue culture; Zinc

Indexed keywords

2,2' DITHIODIPYRIDINE; BUTOXY CARBONYL ASPARTATE FLUOROMETHYLKETONE; DIZOCILPINE; FURA 2; METALLOPROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; N,N,N',N' TETRAKIS(2 PYRIDYLMETHYL)ETHYLENEDIAMINE; OXIDIZING AGENT; PROTEINASE INHIBITOR; TETRYLAMMONIUM; THIOL DERIVATIVE; UNCLASSIFIED DRUG; ZINC;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN CORTEX; CHROMATIN STRUCTURE; EMBRYO; INTRACELLULAR TRANSPORT; NERVE CELL; NEUROTOXICITY; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; ZINC METABOLISM;

2,2'-DIPYRIDYL; ANIMALS; APOPTOSIS; CELLS, CULTURED; CHELATING AGENTS; COCULTURE TECHNIQUES; DISULFIDES; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FLUORESCENT DYES; INTRACELLULAR FLUID; L-LACTATE DEHYDROGENASE; N-METHYLASPARTATE; NEUROGLIA; NEURONS; OXIDATION-REDUCTION; POTASSIUM; RATS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SULFHYDRYL COMPOUNDS; SULFHYDRYL REAGENTS; TETRAETHYLAMMONIUM; ZINC;

ANIMALIA;

EID: 0033788519     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.2000.0751878.x     Document Type: Article

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