Peroxynitrite Mediates Neurotoxicity of Amyloid β-Peptide 1-42- and Lipopolysaccharide-Activated Microglia

Journal of Neuroscience

Volumn 22, Issue 9, 2002, Pages 3484-3492

  Xie, Zhong ^a   Wei, Min ^a   Morgan, Todd E ^a   Fabrizio, Paola ^a   Han, Derick ^b   Finch, Caleb E ^a   Longo, Valter D ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

A ; LPS; Microglia; Neurons; Nitric oxide; Peroxynitrite; Superoxide; TNF

Indexed keywords

5,10,15,20 TETRAKIS(4 SULFONATOPHENYL)PORPHYRINATOIRON CHLORIDE; 5,10,15,20 TETRAKIS(N METHYL 4' PYRIDYL)PORPHYRINATOIRON CHLORIDE; AMYLOID BETA PROTEIN; BENZENE DERIVATIVE; COPPER ZINC SUPEROXIDE DISMUTASE; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; PENTOXIFYLLINE; PEROXYNITRITE; PYRIDINE DERIVATIVE; SUPEROXIDE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); ENZYME INHIBITOR; IMMUNOSUPPRESSIVE AGENT; IRON DERIVATIVE; NITRIC OXIDE SYNTHASE; PEPTIDE FRAGMENT; PEROXYNITROUS ACID; THALIDOMIDE; TUMOR NECROSIS FACTOR ALPHA;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BRAIN NERVE CELL; CATALYSIS; CATALYST; COCULTURE; CONTROLLED STUDY; DECOMPOSITION; DRUG SELECTIVITY; ELECTRON SPIN RESONANCE; MICROGLIA; NERVE CELL NECROSIS; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; SYNTHESIS; TREATMENT FAILURE; ANIMAL; CELL CULTURE; CELL SEPARATION; CELL SURVIVAL; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; FISCHER 344 RAT; METABOLISM; NERVE CELL;

AMYLOID BETA-PROTEIN; ANIMALS; CELL SEPARATION; CELL SURVIVAL; CELLS, CULTURED; COCULTURE TECHNIQUES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENZYME INHIBITORS; IMMUNOSUPPRESSIVE AGENTS; INTERFERON TYPE II; IRON COMPOUNDS; LIPOPOLYSACCHARIDES; MICROGLIA; NEURONS; NITRIC OXIDE SYNTHASE; PENTOXIFYLLINE; PEPTIDE FRAGMENTS; PEROXYNITROUS ACID; RATS; RATS, INBRED F344; SUPEROXIDES; THALIDOMIDE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036584232     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-09-03484.2002     Document Type: Article

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