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Volumn 279, Issue 2, 1996, Pages 515-523

Pharmacological properties of acquired excitotoxicity in Chinese hamster ovary cells transfected with N-methyl-D-aspartate receptor subunits

Author keywords

[No Author keywords available]

Indexed keywords

4 PHOSPHONOMETHYLPIPECOLIC ACID; 5,7 DICHLOROKYNURENIC ACID; DIZOCILPINE; EXCITATORY AMINO ACID RECEPTOR; GLUTAMIC ACID; IFENPRODIL; KETAMINE; MUTANT PROTEIN; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; RECEPTOR SUBUNIT; TRAXOPRODIL; UNCLASSIFIED DRUG;

EID: 0030434063     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (57)

References (61)
  • 1
    • 0028934398 scopus 로고
    • Transfection of N-methyl-D-aspartate receptors in a nonneuronal cell line leads to cell death
    • ANEGAWA, N. J., LYNCH, D. R., VERDOORN, T. A. AND PRITCHETT, D. B.: Transfection of N-methyl-D-aspartate receptors in a nonneuronal cell line leads to cell death. J. Neurochem. 64: 2004-2012, 1995.
    • (1995) J. Neurochem. , vol.64 , pp. 2004-2012
    • Anegawa, N.J.1    Lynch, D.R.2    Verdoorn, T.A.3    Pritchett, D.B.4
  • 2
    • 0023929233 scopus 로고
    • The role of divalent cations in the N-methyl-D-aspartate responses of mouse central neurones in culture
    • ASCHER, P. AND NOWAK, L.: The role of divalent cations in the N-methyl-D-aspartate responses of mouse central neurones in culture. J. Physiol. 399: 247-266, 1988.
    • (1988) J. Physiol. , vol.399 , pp. 247-266
    • Ascher, P.1    Nowak, L.2
  • 3
    • 0027234568 scopus 로고
    • Selection of Chinese hamster ovary cells (CHO-K1) with reduced glutamate and aspartate uptake
    • ASH, J. F., IGO, R. P. JR., MORGAN, M. AND GREY, A.: Selection of Chinese hamster ovary cells (CHO-K1) with reduced glutamate and aspartate uptake. Somatic Cell Mol. Genet. 19: 231-243, 1993.
    • (1993) Somatic Cell Mol. Genet. , vol.19 , pp. 231-243
    • Ash, J.F.1    Igo Jr., R.P.2    Morgan, M.3    Grey, A.4
  • 5
    • 0028263401 scopus 로고
    • Stable transfection of the NR1 subunit in Chinese hamster ovary cells fails to produce a functional N-methyl-D-aspartate receptor
    • BOECKMAN, F. A. AND AIZENMAN, E.: Stable transfection of the NR1 subunit in Chinese hamster ovary cells fails to produce a functional N-methyl-D-aspartate receptor. Neurosci. Lett. 173: 189-192, 1994.
    • (1994) Neurosci. Lett. , vol.173 , pp. 189-192
    • Boeckman, F.A.1    Aizenman, E.2
  • 6
    • 1842299289 scopus 로고
    • "Acquisition" of excitotoxicity in Chinese Hamster Ovary (CHO) cells transfected with NMDA receptor subunits: Use of a luciferase reporter assay
    • BOECKMAN, F. A. AND AIZENMAN, E.: "Acquisition" of excitotoxicity in Chinese Hamster Ovary (CHO) cells transfected with NMDA receptor subunits: use of a luciferase reporter assay. Abstr. Soc. Neurosci. 21: 86, 1995.
    • (1995) Abstr. Soc. Neurosci. , vol.21 , pp. 86
    • Boeckman, F.A.1    Aizenman, E.2
  • 7
    • 0027991388 scopus 로고
    • The molecular basis of NMDA receptor subtypes: Native receptor diversity is predicted by subunit composition
    • BULLER, A. L., LARSON, H. C., SCHNEIDER, B. E., BEATON, J. A., MORRISETT, R. A. AND MONAGHAN, D. T.: The molecular basis of NMDA receptor subtypes: Native receptor diversity is predicted by subunit composition. J. Neurosci. 14: 5471-5484, 1994.
    • (1994) J. Neurosci. , vol.14 , pp. 5471-5484
    • Buller, A.L.1    Larson, H.C.2    Schneider, B.E.3    Beaton, J.A.4    Morrisett, R.A.5    Monaghan, D.T.6
  • 8
    • 0026727807 scopus 로고
    • Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor
    • BURNASHEV, N., SCHOEPFER, R., MONYER, H., RUPPERSBERG, J. P., GUNTHER, W., SEEBURG, P. AND SAKMANN, B.: Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor. Science 257: 1415-1419, 1992.
    • (1992) Science , vol.257 , pp. 1415-1419
    • Burnashev, N.1    Schoepfer, R.2    Monyer, H.3    Ruppersberg, J.P.4    Gunther, W.5    Seeburg, P.6    Sakmann, B.7
  • 9
    • 0029028313 scopus 로고
    • Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes
    • BURNASHEV, N., ZHOU, Z., NEHER, E. AND SAKMANN, B.: Fractional calcium currents through recombinant GluR channels of the NMDA, AMPA and kainate receptor subtypes. J. Physiol. 485: 403-418, 1995.
    • (1995) J. Physiol. , vol.485 , pp. 403-418
    • Burnashev, N.1    Zhou, Z.2    Neher, E.3    Sakmann, B.4
  • 10
    • 23444431611 scopus 로고
    • Green fluorescent protein as a marker for gene expression
    • CHALFIE, M., TU, Y., EUSKIRCHEN, G., WARD, W. W. AND PRASHER, D. C.: Green fluorescent protein as a marker for gene expression. Science 263: 802-805, 1994.
    • (1994) Science , vol.263 , pp. 802-805
    • Chalfie, M.1    Tu, Y.2    Euskirchen, G.3    Ward, W.W.4    Prasher, D.C.5
  • 11
    • 0028300468 scopus 로고
    • Inhibition of protein synthesis by the NMDA channel blocker MK-801
    • CHARRIAUT-MARLANGUE, C., DESSI, F. AND BEN-ARI, Y.: Inhibition of protein synthesis by the NMDA channel blocker MK-801. Neuroreport 5: 1110-1112, 1994.
    • (1994) Neuroreport , vol.5 , pp. 1110-1112
    • Charriaut-Marlangue, C.1    Dessi, F.2    Ben-Ari, Y.3
  • 12
    • 0027938709 scopus 로고
    • Molecular characterization of N-methyl-D-aspartate receptors expressed in mammalian cells yields evidence for the coexistence of three subunit types within a discrete receptor molecule
    • CHAZOT, P. L., COLEMAN, S. K., CIK, M. AND STEPHENSON, F. A.: Molecular characterization of N-methyl-D-aspartate receptors expressed in mammalian cells yields evidence for the coexistence of three subunit types within a discrete receptor molecule. J. Biol. Chem. 269: 24403-24409, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 24403-24409
    • Chazot, P.L.1    Coleman, S.K.2    Cik, M.3    Stephenson, F.A.4
  • 14
    • 0023137252 scopus 로고
    • Ionic dependence of glutamate neurotoxicity
    • CHOI, D. W.: Ionic dependence of glutamate neurotoxicity. J. Neurosci. 7: 369-379, 1987.
    • (1987) J. Neurosci. , vol.7 , pp. 369-379
    • Choi, D.W.1
  • 15
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • CHOI, D. W.: Excitotoxic cell death. J. Neurobiol. 23: 1261-1276, 1992.
    • (1992) J. Neurobiol. , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 16
    • 0027746221 scopus 로고
    • Optimal expression of cloned NMDAR1/NMDAR2A heteromeric glutamate receptors: A biochemical characterization
    • CIK, M., CHAZOT, P. L. AND STEPHENSON, F. A.: Optimal expression of cloned NMDAR1/NMDAR2A heteromeric glutamate receptors: a biochemical characterization. Biochem. J. 296: 877-883, 1993.
    • (1993) Biochem. J. , vol.296 , pp. 877-883
    • Cik, M.1    Chazot, P.L.2    Stephenson, F.A.3
  • 17
    • 0028157126 scopus 로고
    • Expression of NMDAR1-1a (N598Q)/NMDAR2A receptors results in decreased cell mortality
    • CIK, M., CHAZOT, P. L. AND STEPHENSON, F. A.: Expression of NMDAR1-1a (N598Q)/NMDAR2A receptors results in decreased cell mortality. Eur. J. Pharmacol. 266: R1-R3, 1994.
    • (1994) Eur. J. Pharmacol. , vol.266
    • Cik, M.1    Chazot, P.L.2    Stephenson, F.A.3
  • 18
    • 0022002328 scopus 로고
    • Cellular uptake disquises action of L-glutamate on N-methyl-D-aspartate receptors
    • GARTHWAITE, J.: Cellular uptake disquises action of L-glutamate on N-methyl-D-aspartate receptors. Br. J. Pharmacol. 85: 297-307, 1985.
    • (1985) Br. J. Pharmacol. , vol.85 , pp. 297-307
    • Garthwaite, J.1
  • 19
    • 0022544178 scopus 로고
    • Neurotoxicity of excitatory amino acid receptor agonists in rat cerebellar slices: Dependence on calcium concentration
    • GARTHWAITE, G. AND GARTHWAITE, J.: Neurotoxicity of excitatory amino acid receptor agonists in rat cerebellar slices: Dependence on calcium concentration. Neurosci. Lett. 66: 193-198, 1986.
    • (1986) Neurosci. Lett. , vol.66 , pp. 193-198
    • Garthwaite, G.1    Garthwaite, J.2
  • 20
    • 0024478028 scopus 로고
    • 2+ of N-methyl-D-aspartate and quisqualate neurotoxicity in young rat hippocampal slices
    • 2+ of N-methyl-D-aspartate and quisqualate neurotoxicity in young rat hippocampal slices. Neurosci. Lett. 97: 316-322, 1989.
    • (1989) Neurosci. Lett. , vol.97 , pp. 316-322
    • Garthwatte, G.1    Garthwaite, J.2
  • 21
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • GOSSEN, M. AND BUJARD, H.: Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. U.S.A. 89: 5547-5551, 1992.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 22
    • 12644263365 scopus 로고
    • Heteromeric NMDA receptor calcium responses measured using aequorin bioluminescence
    • GRANT, E. R., KRICKA, L., PLEASURE, D. E. AND LYNCH, D. R.: Heteromeric NMDA receptor calcium responses measured using aequorin bioluminescence. Abstr. Soc. Neurosci. 21: 841, 1995.
    • (1995) Abstr. Soc. Neurosci. , vol.21 , pp. 841
    • Grant, E.R.1    Kricka, L.2    Pleasure, D.E.3    Lynch, D.R.4
  • 24
    • 0001249750 scopus 로고
    • Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: Selective binding to open channels
    • HUETTNER, J. E. AND BEAN, B. P.: Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: Selective binding to open channels. Proc. Natl. Acad. Sci. U.S.A. 85: 1307-1311, 1988.
    • (1988) Proc. Natl. Acad. Sci. U.S.A. , vol.85 , pp. 1307-1311
    • Huettner, J.E.1    Bean, B.P.2
  • 27
    • 0027385330 scopus 로고
    • Multiple structural determinants of voltage-dependent magnesium block in recombinant NMDA receptors
    • KAWAJIRI, S. AND DINGLEDINE, R.: Multiple structural determinants of voltage-dependent magnesium block in recombinant NMDA receptors. Neuropharmacology 32: 1203-1211, 1993.
    • (1993) Neuropharmacology , vol.32 , pp. 1203-1211
    • Kawajiri, S.1    Dingledine, R.2
  • 28
    • 0025013048 scopus 로고
    • Construction of cell lines that express high levels of the human estrogen receptor and are killed by estrogens
    • KUSHNER, P. J., HORT, E., SHINE, J., BAXTER, J. D. AND GREENE, G. L.: Construction of cell lines that express high levels of the human estrogen receptor and are killed by estrogens. Mol. Endocrinol. 4: 1465-1473, 1990.
    • (1990) Mol. Endocrinol. , vol.4 , pp. 1465-1473
    • Kushner, P.J.1    Hort, E.2    Shine, J.3    Baxter, J.D.4    Greene, G.L.5
  • 30
    • 0028169661 scopus 로고
    • Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition
    • LAURIE, D. J. AND SEEBURG, P. H.: Ligand affinities at recombinant N-methyl-D-aspartate receptors depend on subunit composition. Eur. J. Pharmacol. 268: 335-345, 1994.
    • (1994) Eur. J. Pharmacol. , vol.268 , pp. 335-345
    • Laurie, D.J.1    Seeburg, P.H.2
  • 31
    • 0028197319 scopus 로고
    • N-methyl-D-aspartate receptors: Different subunit requirements for binding of glutamate antagonists, glycine antagonists, and channel-blocking agents
    • LYNCH, D. R., ANEGAWA, N. J., VERDOORN, T. AND PRITCHETT, D. B.: N-methyl-D-aspartate receptors: different subunit requirements for binding of glutamate antagonists, glycine antagonists, and channel-blocking agents. Mol. Pharmacol. 45: 540-545, 1994.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 540-545
    • Lynch, D.R.1    Anegawa, N.J.2    Verdoorn, T.3    Pritchett, D.B.4
  • 32
    • 0022479032 scopus 로고
    • NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones
    • MACDERMOTT, A. B., MAYER, M. L., WESTBROOK, G. L., SMITH, S. J. AND BARKER, J. L.: NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones. Nature 321: 519-522, 1986.
    • (1986) Nature , vol.321 , pp. 519-522
    • Macdermott, A.B.1    Mayer, M.L.2    Westbrook, G.L.3    Smith, S.J.4    Barker, J.L.5
  • 33
    • 0023232903 scopus 로고
    • Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine
    • MACDONALD, J. F., MILJKOVIC, Z. AND PENNEFATHER, P.: Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine. J. Neurophysiol. 58: 251-266, 1987.
    • (1987) J. Neurophysiol. , vol.58 , pp. 251-266
    • Macdonald, J.F.1    Miljkovic, Z.2    Pennefather, P.3
  • 34
    • 0023125256 scopus 로고
    • The physiology of excitatory amino acids in the vertebrate central nervous system
    • MAYER, M. L. AND WESTBROOK, G. L.: The physiology of excitatory amino acids in the vertebrate central nervous system. Prog. Neurobiol. 28: 197-276, 1987.
    • (1987) Prog. Neurobiol. , vol.28 , pp. 197-276
    • Mayer, M.L.1    Westbrook, G.L.2
  • 41
    • 0029613879 scopus 로고
    • Excitotoxic cell death and delayed rescue in human neurons derived from NT2 cells
    • MUNIR, M., LU, L. AND MCGONIGLE, P.: Excitotoxic cell death and delayed rescue in human neurons derived from NT2 cells. J. Neurosci. 15: 7847-7860, 1995.
    • (1995) J. Neurosci. , vol.15 , pp. 7847-7860
    • Munir, M.1    Lu, L.2    Mcgonigle, P.3
  • 44
  • 45
    • 0024406708 scopus 로고
    • Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex
    • ROSENBERG, P. A. AND AIZENMAN, E.: Hundred-fold increase in neuronal vulnerability to glutamate toxicity in astrocyte-poor cultures of rat cerebral cortex. Neurosci. Lett. 103: 162-168, 1989.
    • (1989) Neurosci. Lett. , vol.103 , pp. 162-168
    • Rosenberg, P.A.1    Aizenman, E.2
  • 46
    • 0026596688 scopus 로고
    • Glutamate uptake disquises neurotoxic potency of glutamate agonists in cerebral cortex in dissociated cell culture
    • ROSENBERG, P. A., AMIN, S. AND LEITNER, M.: Glutamate uptake disquises neurotoxic potency of glutamate agonists in cerebral cortex in dissociated cell culture. J. Neurosci. 12: 56-61, 1992.
    • (1992) J. Neurosci. , vol.12 , pp. 56-61
    • Rosenberg, P.A.1    Amin, S.2    Leitner, M.3
  • 47
    • 0022620257 scopus 로고
    • Glutamate and the pathophysiology of hypoxic-ischemic brain damage
    • ROTHMAN, S. M. AND OLNEY, J. W.: Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann. Neurol. 19: 105-111, 1986.
    • (1986) Ann. Neurol. , vol.19 , pp. 105-111
    • Rothman, S.M.1    Olney, J.W.2
  • 48
    • 0023261234 scopus 로고
    • Delayed neurotoxicity of excitotoxic amino acids in vitro
    • ROTHMAN, S. M., THURSTON, J. H. AND HAUHART, R. E.: Delayed neurotoxicity of excitotoxic amino acids in vitro. Neuroscience 22: 472-480, 1987.
    • (1987) Neuroscience , vol.22 , pp. 472-480
    • Rothman, S.M.1    Thurston, J.H.2    Hauhart, R.E.3
  • 50
    • 0027339551 scopus 로고
    • ++ and channel blockers by a single amino acid substitution in the N-methyl-D-aspartate receptor
    • ++ and channel blockers by a single amino acid substitution in the N-methyl-D-aspartate receptor. J. Biol. Chem. 268: 410-415, 1993.
    • (1993) J. Biol. Chem. , vol.268 , pp. 410-415
    • Sakurada, K.1    Masu, M.2    Nakanishi, S.3
  • 51
    • 0027327992 scopus 로고
    • Fractional contribution of calcium to the cation current through glutamate receptor channels
    • SCHNEGGENBERGER, R., ZHOU, Z., KONNERTH, A. AND NEHER, E.: Fractional contribution of calcium to the cation current through glutamate receptor channels. Neuron 11: 133-143, 1993.
    • (1993) Neuron , vol.11 , pp. 133-143
    • Schneggenberger, R.1    Zhou, Z.2    Konnerth, A.3    Neher, E.4
  • 52
    • 0028219211 scopus 로고
    • Changing subunit composition of heteromeric NMDA receptors during development of rat cortex
    • SHENG, M., CUMMINGS, J., ROLDAN, L. A., JAN, Y. N. AND JAN, L. Y.: Changing subunit composition of heteromeric NMDA receptors during development of rat cortex. Nature 368: 144-147, 1994.
    • (1994) Nature , vol.368 , pp. 144-147
    • Sheng, M.1    Cummings, J.2    Roldan, L.A.3    Jan, Y.N.4    Jan, L.Y.5
  • 53
    • 0028059990 scopus 로고
    • Comparison of the potency of competitive NMDA antagonists against the neurotoxicity of glutamate and NMDA
    • SPELIOTES, E. K., HARTNETT, K. A., BLITZBLAU, R. C., AIZENMAN, E. AND ROSENBERG, P. A.: Comparison of the potency of competitive NMDA antagonists against the neurotoxicity of glutamate and NMDA. J. Neurochem. 63: 879-885, 1994.
    • (1994) J. Neurochem. , vol.63 , pp. 879-885
    • Speliotes, E.K.1    Hartnett, K.A.2    Blitzblau, R.C.3    Aizenman, E.4    Rosenberg, P.A.5
  • 54
    • 0027099647 scopus 로고
    • Single-channel conductances of NMDA receptors expressed from cloned cDNAs: Comparison with native recpetors
    • STERN, P., BÉHÉ, P., SCHOEPFER, R. AND COLQUHOUN, D.: Single-channel conductances of NMDA receptors expressed from cloned cDNAs: Comparison with native recpetors. Proc. Roy. Soc. Lond. B 250: 271-277, 1992.
    • (1992) Proc. Roy. Soc. Lond. B , vol.250 , pp. 271-277
    • Stern, P.1    Béhé, P.2    Schoepfer, R.3    Colquhoun, D.4
  • 55
    • 0027289375 scopus 로고
    • The modulation of N-methyl-D-aspartate receptors by redox and alkylating reagents in rat cortical neurons in vitro
    • TANG, L.-H., AND AIZENMAN, E.: The modulation of N-methyl-D-aspartate receptors by redox and alkylating reagents in rat cortical neurons in vitro. J. Physiol. 465: 303-323, 1993.
    • (1993) J. Physiol. , vol.465 , pp. 303-323
    • Tang, L.-H.1    Aizenman, E.2
  • 57
    • 0027290548 scopus 로고
    • Glutamate receptor-mediated currents and toxicity in embryonal carcinoma cells
    • TURETSKY, D. M., HUETTNER, J. E., GOTTLIEB, D. I., GOLDBERG, M. P. AND CHOI, D. W.: Glutamate receptor-mediated currents and toxicity in embryonal carcinoma cells. J. Neurobiol. 24: 1157-1169, 1993.
    • (1993) J. Neurobiol. , vol.24 , pp. 1157-1169
    • Turetsky, D.M.1    Huettner, J.E.2    Gottlieb, D.I.3    Goldberg, M.P.4    Choi, D.W.5
  • 58
    • 0027440215 scopus 로고
    • Preferential co-assembly of recombinant NMDA receptors composed of three different subunits
    • WAFFORD, K. A., BAIN, C. J., LE BOURDELLES, B., WHITING, P. J. AND KEMP, J. A.: Preferential co-assembly of recombinant NMDA receptors composed of three different subunits. NeuroReport 4: 1347-1349, 1993.
    • (1993) NeuroReport , vol.4 , pp. 1347-1349
    • Wafford, K.A.1    Bain, C.J.2    Le Bourdelles, B.3    Whiting, P.J.4    Kemp, J.A.5
  • 59
    • 0027525324 scopus 로고
    • Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: Selectivity and mechanisms at recombinant heteromeric receptors
    • WILLIAMS, K.: Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: Selectivity and mechanisms at recombinant heteromeric receptors. Mol. Pharmacol. 44: 851-859, 1993.
    • (1993) Mol. Pharmacol. , vol.44 , pp. 851-859
    • Williams, K.1
  • 60
    • 0026560041 scopus 로고
    • Cloning, expression and modulation of a mouse NMDA receptor subunit
    • YAMAZAKI, M., MORI, H., ARAKI, K., MORI, K. J. AND MISHINA, M.: Cloning, expression and modulation of a mouse NMDA receptor subunit. FEBS Lett. 300: 39-45, 1992.
    • (1992) FEBS Lett. , vol.300 , pp. 39-45
    • Yamazaki, M.1    Mori, H.2    Araki, K.3    Mori, K.J.4    Mishina, M.5
  • 61
    • 0029073172 scopus 로고
    • Alternatively spliced isoforms of the NMDAR1 receptor subunit
    • ZUKIN, R. S. AND BENNETT, M. V. L.: Alternatively spliced isoforms of the NMDAR1 receptor subunit. Trends Neurosci. 18: 306-313, 1995.
    • (1995) Trends Neurosci. , vol.18 , pp. 306-313
    • Zukin, R.S.1    Bennett, M.V.L.2


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