-
1
-
-
0037228105
-
Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey
-
Coresh J, Astor BC, Greene T et al. Prevalence of chronic kidney disease and decreased kidney function in the adult US population: Third National Health and Nutrition Examination Survey. Am J Kidney Dis 2003; 41: 1-12.
-
(2003)
Am J Kidney Dis
, vol.41
, pp. 1-12
-
-
Coresh, J.1
Astor, B.C.2
Greene, T.3
-
3
-
-
0031706336
-
Progression of glomerular diseases: Is the podocyte the culprit?
-
Kriz W, Gretz N, Lemley KV. Progression of glomerular diseases: is the podocyte the culprit? Kidney Int 1998; 54: 687-697.
-
(1998)
Kidney Int
, vol.54
, pp. 687-697
-
-
Kriz, W.1
Gretz, N.2
Lemley, K.V.3
-
4
-
-
29144490392
-
Podocyte depletion causes glomerulosclerosis: Diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene
-
Wharram BL, Goyal M, Wiggins JE et al. Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene. J Am Soc Nephrol 2005; 16: 2941-2952.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 2941-2952
-
-
Wharram, B.L.1
Goyal, M.2
Wiggins, J.E.3
-
5
-
-
0026440208
-
The long-term prognosis of the primary glomerulonephritides. A morphological and clinical analysis of 1747 cases
-
Bohle A, Wehrmann M, Bogenschutz O et al. The long-term prognosis of the primary glomerulonephritides. A morphological and clinical analysis of 1747 cases. Pathol Res Pract 1992; 188: 908-924.
-
(1992)
Pathol Res Pract
, vol.188
, pp. 908-924
-
-
Bohle, A.1
Wehrmann, M.2
Bogenschutz, O.3
-
6
-
-
0025816170
-
Characterization of human renal fibroblasts in health and disease: II. In vitro growth, differentiation, and collagen synthesis of fibroblasts from kidneys with interstitial fibrosis
-
Rodemann HP, Muller GA. Characterization of human renal fibroblasts in health and disease: II. In vitro growth, differentiation, and collagen synthesis of fibroblasts from kidneys with interstitial fibrosis. Am J Kidney Dis 1991; 17: 684-686.
-
(1991)
Am J Kidney Dis
, vol.17
, pp. 684-686
-
-
Rodemann, H.P.1
Muller, G.A.2
-
7
-
-
33748316445
-
The role of renin-angiotensin-aldosterone system in the progression of chronic kidney disease
-
Remuzzi G, Perico N, Macia M et al. The role of renin-angiotensin-aldosterone system in the progression of chronic kidney disease. Kidney Int Suppl 2005; 99: S57-S65.
-
(2005)
Kidney Int Suppl
, vol.99
-
-
Remuzzi, G.1
Perico, N.2
Macia, M.3
-
8
-
-
0031718296
-
Cellular apoptosis and proliferation in experimental renal fibrosis
-
Thomas GL, Yang B, Wagner BE et al. Cellular apoptosis and proliferation in experimental renal fibrosis. Nephrol Dial Transplant 1998; 13: 2216-2226.
-
(1998)
Nephrol Dial Transplant
, vol.13
, pp. 2216-2226
-
-
Thomas, G.L.1
Yang, B.2
Wagner, B.E.3
-
9
-
-
0030752624
-
Extraglomerular origin of the mesangial cell after injury. A new role of the juxtaglomerular apparatus
-
Hugo C, Shankland SJ, Bowen-Pope DF et al. Extraglomerular origin of the mesangial cell after injury. A new role of the juxtaglomerular apparatus. J Clin Invest 1997; 100: 786-794.
-
(1997)
J Clin Invest
, vol.100
, pp. 786-794
-
-
Hugo, C.1
Shankland, S.J.2
Bowen-Pope, D.F.3
-
10
-
-
20044361816
-
Uninephrectomy induces progressive glomerulosclerosis and apoptosis in anti-Thy1 glomerulonephritis
-
Sakai N, Iseki K, Suzuki S et al. Uninephrectomy induces progressive glomerulosclerosis and apoptosis in anti-Thy1 glomerulonephritis. Pathol Int 2005; 55: 19-26.
-
(2005)
Pathol Int
, vol.55
, pp. 19-26
-
-
Sakai, N.1
Iseki, K.2
Suzuki, S.3
-
12
-
-
0042384662
-
The pathogenesis of 'classic' focal segmental glomerulosclerosis-lessons from rat models
-
vi39-vi44
-
Kriz W. The pathogenesis of 'classic' focal segmental glomerulosclerosis-lessons from rat models. Nephrol Dial Transplant 2003; 18(Suppl 6): vi39-vi44.
-
(2003)
Nephrol Dial Transplant
, vol.18
, Issue.SUPPL. 6
-
-
Kriz, W.1
-
13
-
-
0037850983
-
Effects of caspase inhibition on the progression of experimental glomerulonephritis
-
Yang B, Johnson TS, Haylor JL et al. Effects of caspase inhibition on the progression of experimental glomerulonephritis. Kidney Int 2003; 63: 2050-2064.
-
(2003)
Kidney Int
, vol.63
, pp. 2050-2064
-
-
Yang, B.1
Johnson, T.S.2
Haylor, J.L.3
-
14
-
-
0036380964
-
A shift in the Bax/Bcl-2 balance may activate caspase-3 and modulate apoptosis in experimental glomerulonephritis
-
Yang B, Johnson TS, Thomas GL et al. A shift in the Bax/Bcl-2 balance may activate caspase-3 and modulate apoptosis in experimental glomerulonephritis. Kidney Int 2002; 62: 1301-1313.
-
(2002)
Kidney Int
, vol.62
, pp. 1301-1313
-
-
Yang, B.1
Johnson, T.S.2
Thomas, G.L.3
-
15
-
-
20844437067
-
-
Hughes J, Savill JS. Apoptosis in glomerulonephritis. Curr Opin Nephrol Hypertens 2005; 14: 389-395.
-
Hughes J, Savill JS. Apoptosis in glomerulonephritis. Curr Opin Nephrol Hypertens 2005; 14: 389-395.
-
-
-
-
16
-
-
0034922498
-
Myofibroblast: A prognostic marker and target cell in progressive renal disease
-
Badid C, Vincent M, Fouque D et al. Myofibroblast: a prognostic marker and target cell in progressive renal disease. Ren Fail 2001; 23: 543-549.
-
(2001)
Ren Fail
, vol.23
, pp. 543-549
-
-
Badid, C.1
Vincent, M.2
Fouque, D.3
-
17
-
-
36249024362
-
A new look at platelet-derived growth factor and renal disease
-
in press
-
Floege J, Eitner F, Alpers C. A new look at platelet-derived growth factor and renal disease. J Am Soc Nephrol 2007 (in press).
-
(2007)
J Am Soc Nephrol
-
-
Floege, J.1
Eitner, F.2
Alpers, C.3
-
18
-
-
33746845181
-
Cardiotoxicity of the cancer therapeutic agent imatinib mesylate
-
Kerkela R, Grazette L, Yacobi R et al. Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nat Med 2006; 12: 908-916.
-
(2006)
Nat Med
, vol.12
, pp. 908-916
-
-
Kerkela, R.1
Grazette, L.2
Yacobi, R.3
-
19
-
-
33646482407
-
Altered bone and mineral metabolism in patients receiving imatinib mesylate
-
Berman E, Nicolaides M, Maki RG et al. Altered bone and mineral metabolism in patients receiving imatinib mesylate. N Engl J Med 2006; 354: 2006-2013.
-
(2006)
N Engl J Med
, vol.354
, pp. 2006-2013
-
-
Berman, E.1
Nicolaides, M.2
Maki, R.G.3
-
20
-
-
4644286909
-
Prevention of renal vascular and glomerular fibrosis by epidermal growth factor receptor inhibition
-
Francois H, Placier S, Flamant M et al. Prevention of renal vascular and glomerular fibrosis by epidermal growth factor receptor inhibition. FASEB J 2004; 18: 926-928.
-
(2004)
FASEB J
, vol.18
, pp. 926-928
-
-
Francois, H.1
Placier, S.2
Flamant, M.3
-
21
-
-
23844557144
-
Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: A new therapeutic approach
-
Lautrette A, Li S, Alili R et al. Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach. Nat Med 2005; 11: 867-874.
-
(2005)
Nat Med
, vol.11
, pp. 867-874
-
-
Lautrette, A.1
Li, S.2
Alili, R.3
-
22
-
-
0027350174
-
Factors involved in the regulation of mesangial cell proliferation in vitro and in vivo
-
Floege J, Eng E, Young BA et al. Factors involved in the regulation of mesangial cell proliferation in vitro and in vivo. Kidney Int Suppl 1993; 39: S47-S54.
-
(1993)
Kidney Int Suppl
, vol.39
-
-
Floege, J.1
Eng, E.2
Young, B.A.3
-
23
-
-
0024442221
-
Growth factor regulation of the renal cortical tubular cells by epidermal growth factor, insulin-like growth factor-I, acidic and basic fibroblast growth factor, and transforming growth factor-beta in serum free culture
-
Kanda S, Nomata K, Saha PK et al. Growth factor regulation of the renal cortical tubular cells by epidermal growth factor, insulin-like growth factor-I, acidic and basic fibroblast growth factor, and transforming growth factor-beta in serum free culture. Cell Biol Int Rep 1989; 13: 687-699.
-
(1989)
Cell Biol Int Rep
, vol.13
, pp. 687-699
-
-
Kanda, S.1
Nomata, K.2
Saha, P.K.3
-
24
-
-
0024505179
-
Regulation of bovine glomerular endothelial cell growth in vitro
-
Ballermann BJ. Regulation of bovine glomerular endothelial cell growth in vitro. Am J Physiol 1989; 256: C182-C189.
-
(1989)
Am J Physiol
, vol.256
-
-
Ballermann, B.J.1
-
25
-
-
0026704619
-
Basic fibroblast growth factor promotes proliferation of rat glomerular visceral epithelial cells in vitro
-
Takeuchi A, Yoshizawa N, Yamamoto M et al. Basic fibroblast growth factor promotes proliferation of rat glomerular visceral epithelial cells in vitro. Am J Pathol 1992; 141: 107-116.
-
(1992)
Am J Pathol
, vol.141
, pp. 107-116
-
-
Takeuchi, A.1
Yoshizawa, N.2
Yamamoto, M.3
-
26
-
-
0034112481
-
Basic fibroblast growth factor expression is increased in human renal fibrogenesis and may mediate autocrine fibroblast proliferation
-
Strutz F, Zeisberg M, Hemmerlein B et al. Basic fibroblast growth factor expression is increased in human renal fibrogenesis and may mediate autocrine fibroblast proliferation. Kidney Int 2000; 57: 1521-1538.
-
(2000)
Kidney Int
, vol.57
, pp. 1521-1538
-
-
Strutz, F.1
Zeisberg, M.2
Hemmerlein, B.3
-
27
-
-
0036233040
-
Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation
-
Strutz F, Zeisberg M, Ziyadeh FN et al. Role of basic fibroblast growth factor-2 in epithelial-mesenchymal transformation. Kidney Int 2002; 61: 1714-1728.
-
(2002)
Kidney Int
, vol.61
, pp. 1714-1728
-
-
Strutz, F.1
Zeisberg, M.2
Ziyadeh, F.N.3
-
28
-
-
0028817922
-
Basic fibroblast growth factor augments podocyte injury and induces glomerulosclerosis in rats with experimental membranous nephropathy
-
Floege J, Kriz W, Schulze M et al. Basic fibroblast growth factor augments podocyte injury and induces glomerulosclerosis in rats with experimental membranous nephropathy. J Clin Invest 1995; 96: 2809-2819.
-
(1995)
J Clin Invest
, vol.96
, pp. 2809-2819
-
-
Floege, J.1
Kriz, W.2
Schulze, M.3
-
29
-
-
0031970626
-
Endogenous fibroblast growth factor-2 mediates cytotoxicity in experimental mesangioproliferative glomerulonephritis
-
Floege J, Burg M, Hugo C et al. Endogenous fibroblast growth factor-2 mediates cytotoxicity in experimental mesangioproliferative glomerulonephritis. J Am Soc Nephrol 1998; 9: 792-801.
-
(1998)
J Am Soc Nephrol
, vol.9
, pp. 792-801
-
-
Floege, J.1
Burg, M.2
Hugo, C.3
-
31
-
-
1942506665
-
Reversal of collapsing glomerulopathy in mice with the cyclin-dependent kinase inhibitor CYC202
-
Gherardi D, D'Agati V, Chu TH et al. Reversal of collapsing glomerulopathy in mice with the cyclin-dependent kinase inhibitor CYC202. J Am Soc Nephrol 2004; 15: 1212-1222.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 1212-1222
-
-
Gherardi, D.1
D'Agati, V.2
Chu, T.H.3
-
32
-
-
0030781307
-
Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with roscovitine, a novel cyclin-dependent kinase antagonist
-
Pippin JW, Qu Q, Meijer L et al. Direct in vivo inhibition of the nuclear cell cycle cascade in experimental mesangial proliferative glomerulonephritis with roscovitine, a novel cyclin-dependent kinase antagonist. J Clin Invest 1997; 100: 2512-2520.
-
(1997)
J Clin Invest
, vol.100
, pp. 2512-2520
-
-
Pippin, J.W.1
Qu, Q.2
Meijer, L.3
-
33
-
-
33845909549
-
Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine
-
Bukanov NO, Smith LA, Klinger KW et al. Long-lasting arrest of murine polycystic kidney disease with CDK inhibitor roscovitine. Nature 2006; 444: 949-952.
-
(2006)
Nature
, vol.444
, pp. 949-952
-
-
Bukanov, N.O.1
Smith, L.A.2
Klinger, K.W.3
-
34
-
-
21344470149
-
TGF-beta1-induced connective tissue growth factor (CCN2) expression in human renal proximal tubule epithelial cells requires Ras/MEK/ERK and Smad signalling
-
Phanish MK, Wahab NA, Hendry BM et al. TGF-beta1-induced connective tissue growth factor (CCN2) expression in human renal proximal tubule epithelial cells requires Ras/MEK/ERK and Smad signalling. Nephron Exp Nephrol 2005; 100: e156-e165.
-
(2005)
Nephron Exp Nephrol
, vol.100
-
-
Phanish, M.K.1
Wahab, N.A.2
Hendry, B.M.3
-
35
-
-
0036014929
-
In vivo identification of the mitogen-activated protein kinase cascade as a central pathogenic pathway in experimental mesangioproliferative glomerulonephritis
-
Bokemeyer D, Panek D, Kramer HJ et al. In vivo identification of the mitogen-activated protein kinase cascade as a central pathogenic pathway in experimental mesangioproliferative glomerulonephritis. J Am Soc Nephrol 2002; 13: 1473-1480.
-
(2002)
J Am Soc Nephrol
, vol.13
, pp. 1473-1480
-
-
Bokemeyer, D.1
Panek, D.2
Kramer, H.J.3
-
36
-
-
0037264633
-
Targeting RAS signalling pathways in cancer therapy
-
Downward J. Targeting RAS signalling pathways in cancer therapy. Nat Rev Cancer 2003; 3: 11-22.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 11-22
-
-
Downward, J.1
-
37
-
-
12344324705
-
MEK inhibitor, U0126, attenuates cisplatin-induced renal injury by decreasing inflammation and apoptosis
-
Jo SK, Cho WY, Sung SA et al. MEK inhibitor, U0126, attenuates cisplatin-induced renal injury by decreasing inflammation and apoptosis. Kidney Int 2005; 67: 458-466.
-
(2005)
Kidney Int
, vol.67
, pp. 458-466
-
-
Jo, S.K.1
Cho, W.Y.2
Sung, S.A.3
-
38
-
-
33646948499
-
Extracellular signal-regulated kinase inhibition slows disease progression in mice with polycystic kidney disease
-
Omori S, Hida M, Fujita H et al. Extracellular signal-regulated kinase inhibition slows disease progression in mice with polycystic kidney disease. J Am Soc Nephrol 2006; 17: 1604-1614.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 1604-1614
-
-
Omori, S.1
Hida, M.2
Fujita, H.3
-
39
-
-
31544457088
-
Simvastatin protection against acute immune-mediated glomerulonephritis in mice
-
Christensen M, Su AW, Snyder RW et al. Simvastatin protection against acute immune-mediated glomerulonephritis in mice. Kidney Int 2006; 69: 457-463.
-
(2006)
Kidney Int
, vol.69
, pp. 457-463
-
-
Christensen, M.1
Su, A.W.2
Snyder, R.W.3
-
40
-
-
0034716460
-
Prenylation inhibitors in renal disease
-
Khwaja A, O'Connolly J, Hendry BM. Prenylation inhibitors in renal disease. Lancet 2000; 355: 741-744.
-
(2000)
Lancet
, vol.355
, pp. 741-744
-
-
Khwaja, A.1
O'Connolly, J.2
Hendry, B.M.3
-
41
-
-
31544439891
-
Molecular mechanisms and therapeutic strategies of chronic renal injury: Role of rho-kinase in the development of renal injury
-
Hayashi K, Wakino S, Kanda T et al. Molecular mechanisms and therapeutic strategies of chronic renal injury: role of rho-kinase in the development of renal injury. J Pharmacol Sci 2006; 100: 29-33.
-
(2006)
J Pharmacol Sci
, vol.100
, pp. 29-33
-
-
Hayashi, K.1
Wakino, S.2
Kanda, T.3
-
42
-
-
33750693942
-
Signaling mechanism of renal fibrosis in unilateral ureteral obstructive kidney disease in ROCK1 knockout mice
-
Fu P, Liu F, Su S et al. Signaling mechanism of renal fibrosis in unilateral ureteral obstructive kidney disease in ROCK1 knockout mice. J Am Soc Nephrol 2006; 17: 3105-3114.
-
(2006)
J Am Soc Nephrol
, vol.17
, pp. 3105-3114
-
-
Fu, P.1
Liu, F.2
Su, S.3
-
43
-
-
33644830593
-
Mechanisms of disease: Fibroblasts - a new look at an old problem
-
Neilson EG. Mechanisms of disease: fibroblasts - a new look at an old problem. Nat Clin Pract Nephrol 2006; 2: 101-108.
-
(2006)
Nat Clin Pract Nephrol
, vol.2
, pp. 101-108
-
-
Neilson, E.G.1
-
44
-
-
34247637641
-
Hic-5 contributes to epithelial-mesenchymal transformation through a RhoA/ROCK-dependent pathway
-
Tumbarello DA, Turner CE. Hic-5 contributes to epithelial-mesenchymal transformation through a RhoA/ROCK-dependent pathway. J Cell Physiol 2007; 211: 736-747.
-
(2007)
J Cell Physiol
, vol.211
, pp. 736-747
-
-
Tumbarello, D.A.1
Turner, C.E.2
-
45
-
-
15844402989
-
Combining TGF-beta inhibition and angiotensin II blockade results in enhanced antifibrotic effect
-
Yu L, Border WA, Anderson I et al. Combining TGF-beta inhibition and angiotensin II blockade results in enhanced antifibrotic effect. Kidney Int 2004; 66: 1774-1784.
-
(2004)
Kidney Int
, vol.66
, pp. 1774-1784
-
-
Yu, L.1
Border, W.A.2
Anderson, I.3
-
47
-
-
10144227768
-
Inhibition of TGF-beta 1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis
-
Akagi Y, Isaka Y, Arai M et al. Inhibition of TGF-beta 1 expression by antisense oligonucleotides suppressed extracellular matrix accumulation in experimental glomerulonephritis. Kidney Int 1996; 50: 148-155.
-
(1996)
Kidney Int
, vol.50
, pp. 148-155
-
-
Akagi, Y.1
Isaka, Y.2
Arai, M.3
-
48
-
-
0034608948
-
Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice
-
Ziyadeh FN, Hoffman BB, Han DC et al. Long-term prevention of renal insufficiency, excess matrix gene expression, and glomerular mesangial matrix expansion by treatment with monoclonal antitransforming growth factor-beta antibody in db/db diabetic mice. Proc Natl Acad Sci USA 2000; 97: 8015-8020.
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, pp. 8015-8020
-
-
Ziyadeh, F.N.1
Hoffman, B.B.2
Han, D.C.3
-
49
-
-
33748939751
-
IN-1130, a novel transforming growth factor-beta type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy
-
Moon JA, Kim HT, Cho IS et al. IN-1130, a novel transforming growth factor-beta type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy. Kidney Int 2006; 70: 1234-1243.
-
(2006)
Kidney Int
, vol.70
, pp. 1234-1243
-
-
Moon, J.A.1
Kim, H.T.2
Cho, I.S.3
-
50
-
-
2542433088
-
Hepatocyte growth factor antagonizes the profibrotic action of TGF-beta1 in mesangial cells by stabilizing Smad transcriptional corepressor TGIF
-
Dai C, Liu Y. Hepatocyte growth factor antagonizes the profibrotic action of TGF-beta1 in mesangial cells by stabilizing Smad transcriptional corepressor TGIF. J Am Soc Nephrol 2004; 15: 1402-1412.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 1402-1412
-
-
Dai, C.1
Liu, Y.2
-
51
-
-
0037302457
-
Delayed administration of hepatocyte growth factor reduces renal fibrosis in obstructive nephropathy
-
Yang J, Liu Y. Delayed administration of hepatocyte growth factor reduces renal fibrosis in obstructive nephropathy. Am J Physiol Renal Physiol 2003; 284: F349-F357.
-
(2003)
Am J Physiol Renal Physiol
, vol.284
-
-
Yang, J.1
Liu, Y.2
-
52
-
-
0346099296
-
Suppressions of chronic glomerular injuries and TGF-beta 1 production by HGF in attenuation of murine diabetic nephropathy
-
Mizuno S, Nakamura T. Suppressions of chronic glomerular injuries and TGF-beta 1 production by HGF in attenuation of murine diabetic nephropathy. Am J Physiol Renal Physiol 2004; 286: F134-F143.
-
(2004)
Am J Physiol Renal Physiol
, vol.286
-
-
Mizuno, S.1
Nakamura, T.2
-
53
-
-
0035005796
-
Hepatocyte growth factor prevents the development of chronic allograft nephropathy in rats
-
Azuma H, Takahara S, Matsumoto K et al. Hepatocyte growth factor prevents the development of chronic allograft nephropathy in rats. J Am Soc Nephrol 2001; 12: 1280-1292.
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 1280-1292
-
-
Azuma, H.1
Takahara, S.2
Matsumoto, K.3
-
54
-
-
0038717407
-
BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury
-
Zeisberg M, Hanai J, Sugimoto H et al. BMP-7 counteracts TGF-beta1-induced epithelial-to-mesenchymal transition and reverses chronic renal injury. Nat Med 2003; 9: 964-968.
-
(2003)
Nat Med
, vol.9
, pp. 964-968
-
-
Zeisberg, M.1
Hanai, J.2
Sugimoto, H.3
-
55
-
-
0142200415
-
Obstructive nephropathy and renal fibrosis: The role of bone morphogenic protein-7 and hepatocyte growth factor
-
Klahr S, Morrissey J. Obstructive nephropathy and renal fibrosis: the role of bone morphogenic protein-7 and hepatocyte growth factor. Kidney Int Suppl 2003; 87: S105-S112.
-
(2003)
Kidney Int Suppl
, vol.87
-
-
Klahr, S.1
Morrissey, J.2
-
56
-
-
20844462829
-
Low turnover osteodystrophy and vascular calcification are amenable to skeletal anabolism in an animal model of chronic kidney disease and the metabolic syndrome
-
Davies MR, Lund RJ, Mathew S et al. Low turnover osteodystrophy and vascular calcification are amenable to skeletal anabolism in an animal model of chronic kidney disease and the metabolic syndrome. J Am Soc Nephrol 2005; 16: 917-928.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 917-928
-
-
Davies, M.R.1
Lund, R.J.2
Mathew, S.3
-
57
-
-
0036223869
-
Treatment of a murine model of high-turnover renal osteodystrophy by exogenous BMP-7
-
Gonzalez EA, Lund RJ, Martin KJ et al. Treatment of a murine model of high-turnover renal osteodystrophy by exogenous BMP-7. Kidney Int 2002; 61: 1322-1331.
-
(2002)
Kidney Int
, vol.61
, pp. 1322-1331
-
-
Gonzalez, E.A.1
Lund, R.J.2
Martin, K.J.3
-
58
-
-
33748427629
-
Modulator of bone morphogenetic protein activity in the progression of kidney diseases
-
Yanagita M. Modulator of bone morphogenetic protein activity in the progression of kidney diseases. Kidney Int 2006; 70: 989-993.
-
(2006)
Kidney Int
, vol.70
, pp. 989-993
-
-
Yanagita, M.1
-
59
-
-
31044453402
-
Uterine sensitization- associated gene-1 (USAG-1), a novel BMP antagonist expressed in the kidney, accelerates tubular injury
-
Yanagita M, Okuda T, Endo S et al. Uterine sensitization- associated gene-1 (USAG-1), a novel BMP antagonist expressed in the kidney, accelerates tubular injury. J Clin Invest 2006; 116: 70-79.
-
(2006)
J Clin Invest
, vol.116
, pp. 70-79
-
-
Yanagita, M.1
Okuda, T.2
Endo, S.3
-
60
-
-
17644378679
-
Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease
-
Lin J, Patel SR, Cheng X et al. Kielin/chordin-like protein, a novel enhancer of BMP signaling, attenuates renal fibrotic disease. Nat Med 2005; 11: 387-393.
-
(2005)
Nat Med
, vol.11
, pp. 387-393
-
-
Lin, J.1
Patel, S.R.2
Cheng, X.3
-
61
-
-
0037498439
-
Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model
-
Lan HY, Mu W, Tomita N et al. Inhibition of renal fibrosis by gene transfer of inducible Smad7 using ultrasound-microbubble system in rat UUO model. J Am Soc Nephrol 2003; 14: 1535-1548.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 1535-1548
-
-
Lan, H.Y.1
Mu, W.2
Tomita, N.3
-
62
-
-
22344456349
-
Insights into the mechanisms of renal fibrosis: Is it possible to achieve regression?
-
Chatziantoniou C, Dussaule JC. Insights into the mechanisms of renal fibrosis: is it possible to achieve regression? Am J Physiol Renal Physiol 2005; 289: F227-F234.
-
(2005)
Am J Physiol Renal Physiol
, vol.289
-
-
Chatziantoniou, C.1
Dussaule, J.C.2
-
63
-
-
3042692326
-
Blockade of CCR2 ameliorates progressive fibrosis in kidney
-
Kitagawa K, Wada T, Furuichi K et al. Blockade of CCR2 ameliorates progressive fibrosis in kidney. Am J Pathol 2004; 165: 237-246.
-
(2004)
Am J Pathol
, vol.165
, pp. 237-246
-
-
Kitagawa, K.1
Wada, T.2
Furuichi, K.3
-
64
-
-
24044470598
-
Blocking of monocyte chemoattractant protein-1 during tubulointerstitial nephritis resulted in delayed neutrophil clearance
-
Li P, Garcia GE, Xia Y et al. Blocking of monocyte chemoattractant protein-1 during tubulointerstitial nephritis resulted in delayed neutrophil clearance. Am J Pathol 2005; 167: 637-649.
-
(2005)
Am J Pathol
, vol.167
, pp. 637-649
-
-
Li, P.1
Garcia, G.E.2
Xia, Y.3
-
65
-
-
0038512466
-
Anti-monocyte chemoattractant protein-1 gene therapy attenuates renal injury induced by protein-overload proteinuria
-
Shimizu H, Maruyama S, Yuzawa Y et al. Anti-monocyte chemoattractant protein-1 gene therapy attenuates renal injury induced by protein-overload proteinuria. J Am Soc Nephrol 2003; 14: 1496-1505.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 1496-1505
-
-
Shimizu, H.1
Maruyama, S.2
Yuzawa, Y.3
-
66
-
-
0030903307
-
RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis
-
Lloyd CM, Minto AW, Dorf ME et al. RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis. J Exp Med 1997; 185: 1371-1380.
-
(1997)
J Exp Med
, vol.185
, pp. 1371-1380
-
-
Lloyd, C.M.1
Minto, A.W.2
Dorf, M.E.3
-
67
-
-
21544463993
-
CCR1 blockade reduces interstitial inflammation and fibrosis in mice with glomerulosclerosis and nephrotic syndrome
-
Vielhauer V, Berning E, Eis V et al. CCR1 blockade reduces interstitial inflammation and fibrosis in mice with glomerulosclerosis and nephrotic syndrome. Kidney Int 2004; 66: 2264-2278.
-
(2004)
Kidney Int
, vol.66
, pp. 2264-2278
-
-
Vielhauer, V.1
Berning, E.2
Eis, V.3
-
68
-
-
2542502538
-
Late onset of treatment with a chemokine receptor CCR1 antagonist prevents progression of lupus nephritis in MRL-Fas(lpr) mice
-
Anders HJ, Belemezova E, Eis V et al. Late onset of treatment with a chemokine receptor CCR1 antagonist prevents progression of lupus nephritis in MRL-Fas(lpr) mice. J Am Soc Nephrol 2004; 15: 1504-1513.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 1504-1513
-
-
Anders, H.J.1
Belemezova, E.2
Eis, V.3
-
69
-
-
0036150991
-
A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation
-
Anders HJ, Vielhauer V, Frink M et al. A chemokine receptor CCR-1 antagonist reduces renal fibrosis after unilateral ureter ligation. J Clin Invest 2002; 109: 251-259.
-
(2002)
J Clin Invest
, vol.109
, pp. 251-259
-
-
Anders, H.J.1
Vielhauer, V.2
Frink, M.3
-
70
-
-
33746590243
-
Chemokine receptor CX3CR1 regulates renal interstitial fibrosis after ischemia-reperfusion injury
-
Furuichi K, Gao JL, Murphy PM. Chemokine receptor CX3CR1 regulates renal interstitial fibrosis after ischemia-reperfusion injury. Am J Pathol 2006; 169: 372-387.
-
(2006)
Am J Pathol
, vol.169
, pp. 372-387
-
-
Furuichi, K.1
Gao, J.L.2
Murphy, P.M.3
-
71
-
-
26944448628
-
Protein kinase Cbeta inhibition attenuates osteopontin expression, macrophage recruitment, and tubulointerstitial injury in advanced experimental diabetic nephropathy
-
Kelly DJ, Chanty A, Gow RM et al. Protein kinase Cbeta inhibition attenuates osteopontin expression, macrophage recruitment, and tubulointerstitial injury in advanced experimental diabetic nephropathy. J Am Soc Nephrol 2005; 16: 1654-1660.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 1654-1660
-
-
Kelly, D.J.1
Chanty, A.2
Gow, R.M.3
-
72
-
-
0037315791
-
Protein kinase C beta inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension
-
Kelly DJ, Zhang Y, Hepper C et al. Protein kinase C beta inhibition attenuates the progression of experimental diabetic nephropathy in the presence of continued hypertension. Diabetes 2003; 52: 512-518.
-
(2003)
Diabetes
, vol.52
, pp. 512-518
-
-
Kelly, D.J.1
Zhang, Y.2
Hepper, C.3
-
73
-
-
28644442122
-
The effect of ruboxistaurin on nephropathy in type 2 diabetes
-
Tuttle KR, Bakris GL, Toto RD et al. The effect of ruboxistaurin on nephropathy in type 2 diabetes. Diabetes Care 2005; 28: 2686-2690.
-
(2005)
Diabetes Care
, vol.28
, pp. 2686-2690
-
-
Tuttle, K.R.1
Bakris, G.L.2
Toto, R.D.3
-
74
-
-
0036226458
-
Role of p38 MAPK in transforming growth factor beta stimulation of collagen production by scleroderma and healthy dermal fibroblasts
-
Sato M, Shegogue D, Gore EA et al. Role of p38 MAPK in transforming growth factor beta stimulation of collagen production by scleroderma and healthy dermal fibroblasts. J Invest Dermatol 2002; 118: 704-711.
-
(2002)
J Invest Dermatol
, vol.118
, pp. 704-711
-
-
Sato, M.1
Shegogue, D.2
Gore, E.A.3
-
75
-
-
0034991582
-
Stimulation of pro-alpha(1)(I) collagen by TGF-beta(1) in mesangial cells: Role of the p38 MAPK pathway
-
Chin BY, Mohsenin A, Li SX et al. Stimulation of pro-alpha(1)(I) collagen by TGF-beta(1) in mesangial cells: role of the p38 MAPK pathway. Am J Physiol Renal Physiol 2001; 280: F495-F504.
-
(2001)
Am J Physiol Renal Physiol
, vol.280
-
-
Chin, B.Y.1
Mohsenin, A.2
Li, S.X.3
-
76
-
-
0942287102
-
The role of p38alpha mitogen-activated protein kinase activation in renal fibrosis
-
Stambe C, Atkins RC, Tesch GH et al. The role of p38alpha mitogen-activated protein kinase activation in renal fibrosis. J Am Soc Nephrol 2004; 15: 370-379.
-
(2004)
J Am Soc Nephrol
, vol.15
, pp. 370-379
-
-
Stambe, C.1
Atkins, R.C.2
Tesch, G.H.3
-
77
-
-
33847656703
-
Inhibition of p38 mitogen-activated protein kinase and transforming growth factor-beta1/Smad signaling pathways modulates the development of fibrosis in adriamycin-induced nephropathy
-
Li J, Campanale NV, Liang RJ et al. Inhibition of p38 mitogen-activated protein kinase and transforming growth factor-beta1/Smad signaling pathways modulates the development of fibrosis in adriamycin-induced nephropathy. Am J Pathol 2006; 169: 1527-1540.
-
(2006)
Am J Pathol
, vol.169
, pp. 1527-1540
-
-
Li, J.1
Campanale, N.V.2
Liang, R.J.3
-
78
-
-
0031726578
-
Proteinuria and damage to tubular cells - is complement a culprit?
-
Matsuo S, Morita Y, Mizuno M et al. Proteinuria and damage to tubular cells - is complement a culprit? Nephrol Dial Transplant 1998; 13: 2723-2726.
-
(1998)
Nephrol Dial Transplant
, vol.13
, pp. 2723-2726
-
-
Matsuo, S.1
Morita, Y.2
Mizuno, M.3
-
79
-
-
33947256458
-
Unrestricted C3 activation occurs in Crry-deficient kidneys and rapidly leads to chronic renal failure
-
Bao L, Wang Y, Chang A et al. Unrestricted C3 activation occurs in Crry-deficient kidneys and rapidly leads to chronic renal failure. J Am Soc Nephrol 2007; 18: 811-822.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 811-822
-
-
Bao, L.1
Wang, Y.2
Chang, A.3
-
80
-
-
17844366593
-
Complement inhibitors targeted to the proximal tubule prevent injury in experimental nephrotic syndrome and demonstrate a key role for C5b-9
-
He C, Imai M, Song H et al. Complement inhibitors targeted to the proximal tubule prevent injury in experimental nephrotic syndrome and demonstrate a key role for C5b-9. J Immunol 2005; 174: 5750-5757.
-
(2005)
J Immunol
, vol.174
, pp. 5750-5757
-
-
He, C.1
Imai, M.2
Song, H.3
-
81
-
-
34248199915
-
Complement C5 mediates experimental tubulointerstitial fibrosis
-
Boor P, Konieczny A, Villa L et al. Complement C5 mediates experimental tubulointerstitial fibrosis. J Am Soc Nephrol 2007; 18: 1508-1515.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 1508-1515
-
-
Boor, P.1
Konieczny, A.2
Villa, L.3
-
82
-
-
2442707596
-
The role of vascular endothelial growth factor (VEGF) in renal pathophysiology
-
Schrijvers BF, Flyvbjerg A, De Vriese AS. The role of vascular endothelial growth factor (VEGF) in renal pathophysiology. Kidney Int 2004; 65: 2003-2017.
-
(2004)
Kidney Int
, vol.65
, pp. 2003-2017
-
-
Schrijvers, B.F.1
Flyvbjerg, A.2
De Vriese, A.S.3
-
83
-
-
0037370325
-
Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases
-
Eremina V, Sood M, Haigh J et al. Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases. J Clin Invest 2003; 111: 707-716.
-
(2003)
J Clin Invest
, vol.111
, pp. 707-716
-
-
Eremina, V.1
Sood, M.2
Haigh, J.3
-
84
-
-
0034889558
-
Vascular endothelial growth factor enhances glomerular capillary repair and accelerates resolution of experimentally induced glomerulonephritis
-
Masuda Y, Shimizu A, Mori T et al. Vascular endothelial growth factor enhances glomerular capillary repair and accelerates resolution of experimentally induced glomerulonephritis. Am J Pathol 2001; 159: 599-608.
-
(2001)
Am J Pathol
, vol.159
, pp. 599-608
-
-
Masuda, Y.1
Shimizu, A.2
Mori, T.3
-
85
-
-
0035034655
-
Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetes
-
de Vriese AS, Tilton RG, Elger M et al. Antibodies against vascular endothelial growth factor improve early renal dysfunction in experimental diabetes. J Am Soc Nephrol 2001; 12: 993-1000.
-
(2001)
J Am Soc Nephrol
, vol.12
, pp. 993-1000
-
-
de Vriese, A.S.1
Tilton, R.G.2
Elger, M.3
-
86
-
-
0042343801
-
A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer
-
Yang JC, Haworth L, Sherry RM et al. A randomized trial of bevacizumab, an anti-vascular endothelial growth factor antibody, for metastatic renal cancer. N Engl J Med 2003; 349: 427-434.
-
(2003)
N Engl J Med
, vol.349
, pp. 427-434
-
-
Yang, J.C.1
Haworth, L.2
Sherry, R.M.3
-
87
-
-
0347511753
-
Mediators of diabetic renal disease: The case for tgf-beta as the major mediator
-
Ziyadeh FN. Mediators of diabetic renal disease: the case for tgf-beta as the major mediator. J Am Soc Nephrol 2004; 15(Suppl 1): S55-S57.
-
(2004)
J Am Soc Nephrol
, vol.15
, Issue.SUPPL. 1
-
-
Ziyadeh, F.N.1
-
89
-
-
0030986772
-
The role of transglutaminase in the rat subtotal nephrectomy model of renal fibrosis
-
Johnson TS, Griffin M, Thomas GL et al. The role of transglutaminase in the rat subtotal nephrectomy model of renal fibrosis. J Clin Invest 1997; 99: 2950-2960.
-
(1997)
J Clin Invest
, vol.99
, pp. 2950-2960
-
-
Johnson, T.S.1
Griffin, M.2
Thomas, G.L.3
-
90
-
-
2942631084
-
Tissue transglutaminase: A mediator and predictor of chronic allograft nephropathy?
-
Johnson TS, Abo-Zenah H, Skill JN et al. Tissue transglutaminase: a mediator and predictor of chronic allograft nephropathy? Transplantation 2004; 77: 1667-1675.
-
(2004)
Transplantation
, vol.77
, pp. 1667-1675
-
-
Johnson, T.S.1
Abo-Zenah, H.2
Skill, J.N.3
-
91
-
-
0041342003
-
Tissue transglutaminase and the progression of human renal scarring
-
Johnson TS, El-Koraie AF, Skill NJ et al. Tissue transglutaminase and the progression of human renal scarring. J Am Soc Nephrol 2003; 14: 2052-2062.
-
(2003)
J Am Soc Nephrol
, vol.14
, pp. 2052-2062
-
-
Johnson, T.S.1
El-Koraie, A.F.2
Skill, N.J.3
-
92
-
-
9144241175
-
Inhibition of transglutaminase activity reduces extracellular matrix accumulation induced by high glucose levels in proximal tubular epithelial cells
-
Skill NJ, Johnson TS, Coutts IG et al. Inhibition of transglutaminase activity reduces extracellular matrix accumulation induced by high glucose levels in proximal tubular epithelial cells. J Biol Chem 2004; 279: 47754-47762.
-
(2004)
J Biol Chem
, vol.279
, pp. 47754-47762
-
-
Skill, N.J.1
Johnson, T.S.2
Coutts, I.G.3
|