메뉴 건너뛰기




Volumn 8, Issue 11, 2002, Pages 1310-1317

Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy

Author keywords

[No Author keywords available]

Indexed keywords

CALCINEURIN; CYCLIN DEPENDENT KINASE 7; CYCLIN DEPENDENT KINASE 9; CYCLIN T1; ENDOTHELIN; RNA POLYMERASE II; SMALL NUCLEAR RNA;

EID: 0036851825     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm778     Document Type: Article
Times cited : (210)

References (45)
  • 1
    • 0030969371 scopus 로고    scopus 로고
    • The cellular and molecular response of cardiac myocytes to mechanical stress
    • Sadoshima, J. & Izumo, S. The cellular and molecular response of cardiac myocytes to mechanical stress. Annu. Rev. Physiol. 59, 551-571 (1997).
    • (1997) Annu. Rev. Physiol. , vol.59 , pp. 551-571
    • Sadoshima, J.1    Izumo, S.2
  • 2
    • 0033860692 scopus 로고    scopus 로고
    • Genetic dissection of cardiac growth control pathways
    • MacLellan, W.R. & Schneider, M.D. Genetic dissection of cardiac growth control pathways. Annu. Rev. Physiol. 62, 289-320 (2000).
    • (2000) Annu. Rev. Physiol. , vol.62 , pp. 289-320
    • MacLellan, W.R.1    Schneider, M.D.2
  • 3
    • 0035203498 scopus 로고    scopus 로고
    • Left ventricular mass and cardiovascular morbidity in essential hypertension: The MAVI study
    • Verdecchia, P. et al. Left ventricular mass and cardiovascular morbidity in essential hypertension: The MAVI study. J. Am. Coll. Cardiol. 38, 1829-1835 (2001).
    • (2001) J. Am. Coll. Cardiol. , vol.38 , pp. 1829-1835
    • Verdecchia, P.1
  • 4
    • 0035797832 scopus 로고    scopus 로고
    • Reduction of cardiovascular risk by regression of electrocardiographic markers of left ventricular hypertrophy by the angiotensin-converting enzyme inhibitor ramipril
    • Mathew, J. et al. Reduction of cardiovascular risk by regression of electrocardiographic markers of left ventricular hypertrophy by the angiotensin-converting enzyme inhibitor ramipril. Circulation 104, 1615-1621 (2001).
    • (2001) Circulation , vol.104 , pp. 1615-1621
    • Mathew, J.1
  • 5
    • 0036143851 scopus 로고    scopus 로고
    • Genetic alterations that inhibit in vivo pressure-overload hypertrophy prevent cardiac dysfunction despite increased wall stress
    • Esposito, G. et al. Genetic alterations that inhibit in vivo pressure-overload hypertrophy prevent cardiac dysfunction despite increased wall stress. Circulation 105, 85-92 (2002).
    • (2002) Circulation , vol.105 , pp. 85-92
    • Esposito, G.1
  • 6
    • 0036143823 scopus 로고    scopus 로고
    • Still stressed out but doing fine: Normalization of wall stress is superfluous to maintaining cardiac function in chronic pressure overload
    • Sano, M. & Schneider, M.D. Still stressed out but doing fine: Normalization of wall stress is superfluous to maintaining cardiac function in chronic pressure overload. Circulation 105, 8-10 (2002).
    • (2002) Circulation , vol.105 , pp. 8-10
    • Sano, M.1    Schneider, M.D.2
  • 7
    • 0033152768 scopus 로고    scopus 로고
    • Cardiac hypertrophy: Sorting out the circuitry
    • McKinsey, T.A. & Olson, E.N. Cardiac hypertrophy: Sorting out the circuitry. Curr. Opin. Genet. Develop. 9, 267-274 (1999).
    • (1999) Curr. Opin. Genet. Develop. , vol.9 , pp. 267-274
    • McKinsey, T.A.1    Olson, E.N.2
  • 8
    • 0035051054 scopus 로고    scopus 로고
    • Cytoplasmic signaling pathways that regulate cardiac hypertrophy
    • Molkentin, J.D. & Dorn, G.W., 2nd. Cytoplasmic signaling pathways that regulate cardiac hypertrophy. Annu. Rev. Physiol. 63, 391-426 (2001).
    • (2001) Annu. Rev. Physiol. , vol.63 , pp. 391-426
    • Molkentin, J.D.1    Dorn G.W. II2
  • 9
    • 0032540267 scopus 로고    scopus 로고
    • A calcineurin-dependent transcriptional pathway for cardiac hypertrophy
    • Molkentin, J.D. et al. A calcineurin-dependent transcriptional pathway for cardiac hypertrophy. Cell 93, 215-228 (1998).
    • (1998) Cell , vol.93 , pp. 215-228
    • Molkentin, J.D.1
  • 10
    • 0032543959 scopus 로고    scopus 로고
    • Enhanced Gαq signaling: A common pathway mediates cardiac hypertrophy and apoptotic heart failure
    • Adams, J.W. et al. Enhanced Gαq signaling: A common pathway mediates cardiac hypertrophy and apoptotic heart failure. Proc. Natl. Acad. Sci. USA 95, 10140-10145 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 10140-10145
    • Adams, J.W.1
  • 11
    • 0034105968 scopus 로고    scopus 로고
    • TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice
    • Zhang, D. et al. TAK1 is activated in the myocardium after pressure overload and is sufficient to provoke heart failure in transgenic mice. Nat. Med. 6, 556-563 (2000).
    • (2000) Nat. Med. , vol.6 , pp. 556-563
    • Zhang, D.1
  • 12
    • 0034213075 scopus 로고    scopus 로고
    • The conserved phosphoinositide 3-kinase pathway determines heart size in mice
    • Shioi, T. et al. The conserved phosphoinositide 3-kinase pathway determines heart size in mice. EMBO J. 19, 2537-2548 (2000).
    • (2000) EMBO J. , vol.19 , pp. 2537-2548
    • Shioi, T.1
  • 13
    • 0034383952 scopus 로고    scopus 로고
    • The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice
    • Bueno, O.F. et al. The MEK1-ERK1/2 signaling pathway promotes compensated cardiac hypertrophy in transgenic mice. EMBO J. 19, 6341-6350 (2000).
    • (2000) EMBO J. , vol.19 , pp. 6341-6350
    • Bueno, O.F.1
  • 14
    • 0037133571 scopus 로고    scopus 로고
    • MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq
    • Minamino, T. et al. MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq. Proc. Natl. Acad. Sci. USA 99, 3866-3871 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 3866-3871
    • Minamino, T.1
  • 15
    • 0037154168 scopus 로고    scopus 로고
    • Activated glycogen synthase-3 β suppresses cardiac hypertrophy in vivo
    • Antos, C.L. et al. Activated glycogen synthase-3 β suppresses cardiac hypertrophy in vivo. Proc. Natl. Acad. Sci. USA 99, 907-912 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 907-912
    • Antos, C.L.1
  • 16
    • 0035964313 scopus 로고    scopus 로고
    • Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival
    • Oh, H. et al. Telomerase reverse transcriptase promotes cardiac muscle cell proliferation, hypertrophy, and survival. Proc. Natl. Acad. Sci. USA 98, 10308-10313 (2001).
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 10308-10313
    • Oh, H.1
  • 17
    • 0036200937 scopus 로고    scopus 로고
    • Akt/protein kinase B promotes organ growth in transgenic mice
    • Shioi, T. et al. Akt/protein kinase B promotes organ growth in transgenic mice. Mol. Cell. Biol. 22, 2799-2809, (2002).
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 2799-2809
    • Shioi, T.1
  • 18
    • 0029760928 scopus 로고    scopus 로고
    • Reversible phosphorylation of the C-terminal domain of RNA polymerase II
    • Dahmus, M.E. Reversible phosphorylation of the C-terminal domain of RNA polymerase II. J. Biol. Chem. 271, 19009-19012 (1996).
    • (1996) J. Biol. Chem. , vol.271 , pp. 19009-19012
    • Dahmus, M.E.1
  • 19
    • 0029791943 scopus 로고    scopus 로고
    • Distinct activated and non-activated RNA polymerase II complexes in yeast
    • Akhtar, A., Faye, G. & Bentley, D.L. Distinct activated and non-activated RNA polymerase II complexes in yeast. EMBO J. 15, 4654-4664, (1996).
    • (1996) EMBO J. , vol.15 , pp. 4654-4664
    • Akhtar, A.1    Faye, G.2    Bentley, D.L.3
  • 20
    • 0033564705 scopus 로고    scopus 로고
    • A protein phosphatase functions to recycle RNA polymerase II
    • Cho, H. et al. A protein phosphatase functions to recycle RNA polymerase II. Genes Dev. 13, 1540-1552 (1999).
    • (1999) Genes Dev. , vol.13 , pp. 1540-1552
    • Cho, H.1
  • 21
    • 0037154982 scopus 로고    scopus 로고
    • A unified theory of gene expression
    • Orphanides, G. & Reinberg, D. A unified theory of gene expression. Cell 108, 439-451 (2002).
    • (2002) Cell , vol.108 , pp. 439-451
    • Orphanides, G.1    Reinberg, D.2
  • 22
    • 0035489955 scopus 로고    scopus 로고
    • Control of RNA polymerase II activity by dedicated CTD kinases and phosphatases
    • Majello, B. & Napolitano, G. Control of RNA polymerase II activity by dedicated CTD kinases and phosphatases. Front. Biosci. 6, D1358-1368 (2001).
    • (2001) Front. Biosci. , vol.6
    • Majello, B.1    Napolitano, G.2
  • 23
    • 0031773146 scopus 로고    scopus 로고
    • A Ras-dependent pathway regulates RNA polymerase II phosphorylation in cardiac myocytes: Implications for cardiac hypertrophy
    • Abdellatif, M. et al. A Ras-dependent pathway regulates RNA polymerase II phosphorylation in cardiac myocytes: Implications for cardiac hypertrophy. Mol. Cell. Biol. 18, 6729-6736 (1998).
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 6729-6736
    • Abdellatif, M.1
  • 24
    • 0034968222 scopus 로고    scopus 로고
    • Cyclin T2a gene maps on human chromosome 2q21
    • De Luca, A. et al. Cyclin T2a gene maps on human chromosome 2q21. J. Histochem. Cytochem. 49, 693-698 (2001).
    • (2001) J. Histochem. Cytochem. , vol.49 , pp. 693-698
    • De Luca, A.1
  • 25
    • 0033597346 scopus 로고    scopus 로고
    • Role of the human and murine cyclin T proteins in regulating HIV-1 tat-activation
    • Kwak, Y.T., Ivanov, D., Guo, J., Nee, E. & Gaynor, R.B. Role of the human and murine cyclin T proteins in regulating HIV-1 tat-activation. J. Mol. Biol. 288, 57-69 (1999).
    • (1999) J. Mol. Biol. , vol.288 , pp. 57-69
    • Kwak, Y.T.1    Ivanov, D.2    Guo, J.3    Nee, E.4    Gaynor, R.B.5
  • 26
    • 0033102387 scopus 로고    scopus 로고
    • Interactions between Tat and TAR and human immunodeficiency virus replication are facilitated by human cyclin T1 but not cyclins T2a or T2b
    • Wimmer, J. et al. Interactions between Tat and TAR and human immunodeficiency virus replication are facilitated by human cyclin T1 but not cyclins T2a or T2b. Virology 255, 182-189 (1999).
    • (1999) Virology , vol.255 , pp. 182-189
    • Wimmer, J.1
  • 27
    • 0032031706 scopus 로고    scopus 로고
    • Identification of multiple cyclin subunits of human P-TEFb
    • Peng, J., Zhu, Y., Milton, J.T. & Price, D.H. Identification of multiple cyclin subunits of human P-TEFb. Genes Dev. 12, 755-762 (1998).
    • (1998) Genes Dev. , vol.12 , pp. 755-762
    • Peng, J.1    Zhu, Y.2    Milton, J.T.3    Price, D.H.4
  • 28
    • 0033015220 scopus 로고    scopus 로고
    • Gq signaling in cardiac adaptation and maladaptation
    • Dorn, G.W. & Brown, J.H. Gq signaling in cardiac adaptation and maladaptation. Trends Cardiovasc. Med. 9, 26-34 (1999).
    • (1999) Trends Cardiovasc. Med. , vol.9 , pp. 26-34
    • Dorn, G.W.1    Brown, J.H.2
  • 29
    • 0033537707 scopus 로고    scopus 로고
    • Interactions of endothelin receptor subtypes A and B with Gi, Go, and Gq in reconstituted phospholipid vesicles
    • Doi, T., Sugimoto, H., Arimoto, I., Hiroaki, Y. & Fujiyoshi, Y. Interactions of endothelin receptor subtypes A and B with Gi, Go, and Gq in reconstituted phospholipid vesicles. Biochemistry 38, 3090-3099 (1999).
    • (1999) Biochemistry , vol.38 , pp. 3090-3099
    • Doi, T.1    Sugimoto, H.2    Arimoto, I.3    Hiroaki, Y.4    Fujiyoshi, Y.5
  • 30
    • 0033981108 scopus 로고    scopus 로고
    • Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy
    • Taigen, T., De Windt, L.J., Lim, H.W. & Molkentin, J.D. Targeted inhibition of calcineurin prevents agonist-induced cardiomyocyte hypertrophy. Proc. Natl. Acad. Sci. USA 97, 1196-1201 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 1196-1201
    • Taigen, T.1    De Windt, L.J.2    Lim, H.W.3    Molkentin, J.D.4
  • 31
    • 0036152858 scopus 로고    scopus 로고
    • Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy
    • Asakura, M. et al. Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy. Nature Med. 8, 35-40, (2002).
    • (2002) Nature Med. , vol.8 , pp. 35-40
    • Asakura, M.1
  • 32
    • 0033920260 scopus 로고    scopus 로고
    • Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription
    • Zhou, M. et al. Tat modifies the activity of CDK9 to phosphorylate serine 5 of the RNA polymerase II carboxyl-terminal domain during human immunodeficiency virus type 1 transcription. Mol. Cell. Biol. 20, 5077-5086 (2000).
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 5077-5086
    • Zhou, M.1
  • 33
    • 0032548846 scopus 로고    scopus 로고
    • Growth-related changes in phosphorylation of yeast RNA polymerase II
    • Patturajan, M, et al. Growth-related changes in phosphorylation of yeast RNA polymerase II. J. Biol. Chem. 273, 4689-4694, (1998).
    • (1998) J. Biol. Chem. , vol.273 , pp. 4689-4694
    • Patturajan, M.1
  • 34
    • 0035022568 scopus 로고    scopus 로고
    • The Cdk9 and cyclin T subunits of TAK/P-TEFb localize to splicing factor-rich nuclear speckle regions
    • Herrmann, C.H. & Mancini, M.A. The Cdk9 and cyclin T subunits of TAK/P-TEFb localize to splicing factor-rich nuclear speckle regions. J. Cell. Sci. 114, 1491-1503, (2001).
    • (2001) J. Cell. Sci. , vol.114 , pp. 1491-1503
    • Herrmann, C.H.1    Mancini, M.A.2
  • 35
    • 15144348173 scopus 로고    scopus 로고
    • Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro
    • Zhu, Y. et al. Transcription elongation factor P-TEFb is required for HIV-1 tat transactivation in vitro. Genes Dev. 11, 2622-2632 (1997).
    • (1997) Genes Dev. , vol.11 , pp. 2622-2632
    • Zhu, Y.1
  • 36
    • 0035891271 scopus 로고    scopus 로고
    • The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription
    • Yang, Z., Zhu, Q., Luo, K. & Zhou, Q. The 7SK small nuclear RNA inhibits the CDK9/cyclin T1 kinase to control transcription. Nature 414, 317-322 (2001).
    • (2001) Nature , vol.414 , pp. 317-322
    • Yang, Z.1    Zhu, Q.2    Luo, K.3    Zhou, Q.4
  • 37
    • 0035891288 scopus 로고    scopus 로고
    • 7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes
    • Nguyen, V.T., Kiss, T., Michels, A.A. & Bensaude, O. 7SK small nuclear RNA binds to and inhibits the activity of CDK9/cyclin T complexes. Nature 414, 322-325 (2001).
    • (2001) Nature , vol.414 , pp. 322-325
    • Nguyen, V.T.1    Kiss, T.2    Michels, A.A.3    Bensaude, O.4
  • 38
    • 0037022660 scopus 로고    scopus 로고
    • Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3
    • Gaussin, V. et al. Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3. Proc. Natl. Acad. Sci. USA 99, 2878-2883 (2002).
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 2878-2883
    • Gaussin, V.1
  • 39
    • 0033638442 scopus 로고    scopus 로고
    • FACT relieves DSIF/NELF-mediated inhibition of transcriptional elongation and reveals functional differences between P-TEFb and TFIIH
    • Wada, T. et al. FACT relieves DSIF/NELF-mediated inhibition of transcriptional elongation and reveals functional differences between P-TEFb and TFIIH. Mol. Cell 5, 1067-1072 (2000).
    • (2000) Mol. Cell , vol.5 , pp. 1067-1072
    • Wada, T.1
  • 40
    • 0035943710 scopus 로고    scopus 로고
    • Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo
    • Chao, S.H. & Price, D.H. Flavopiridol inactivates P-TEFb and blocks most RNA polymerase II transcription in vivo. J. Biol. Chem. 276, 31793-31799, (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 31793-31799
    • Chao, S.H.1    Price, D.H.2
  • 41
    • 0029943536 scopus 로고    scopus 로고
    • The human immunodeficiency virus Tat proteins specifically associate with TAK in vivo and require the carboxyl-terminal domain of RNA polymerase II for function
    • Yang, X., Herrmann, C.H. & Rice, A.P. The human immunodeficiency virus Tat proteins specifically associate with TAK in vivo and require the carboxyl-terminal domain of RNA polymerase II for function. J. Virol. 70, 4576-4584 (1996).
    • (1996) J. Virol. , vol.70 , pp. 4576-4584
    • Yang, X.1    Herrmann, C.H.2    Rice, A.P.3
  • 42
    • 0026342911 scopus 로고
    • Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice
    • Subramaniam, A. et al. Tissue-specific regulation of the alpha-myosin heavy chain gene promoter in transgenic mice. J. Biol. Chem. 266, 24613-24620 (1991).
    • (1991) J. Biol. Chem. , vol.266 , pp. 24613-24620
    • Subramaniam, A.1
  • 43
    • 0032478271 scopus 로고    scopus 로고
    • A simplified system for generating recombinant adenoviruses
    • He, T.C. et al. A simplified system for generating recombinant adenoviruses. Proc. Natl. Acad. Sci. USA 95, 2509-2514 (1998).
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 2509-2514
    • He, T.C.1
  • 44
    • 0027943714 scopus 로고
    • Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase
    • Matsuoka, M., Kato, J.Y., Fisher, R.P., Morgan, D.O. & Sherr, C.J. Activation of cyclin-dependent kinase 4 (cdk4) by mouse MO15-associated kinase. Mol. Cell. Biol. 14, 7265-7275 (1994).
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 7265-7275
    • Matsuoka, M.1    Kato, J.Y.2    Fisher, R.P.3    Morgan, D.O.4    Sherr, C.J.5
  • 45
    • 0034688264 scopus 로고    scopus 로고
    • Physical interaction between CDK9 and B-Myb results in suppression of B-Myb gene autoregulation
    • de Falco, G. et al. Physical interaction between CDK9 and B-Myb results in suppression of B-Myb gene autoregulation. Oncogene 19, 373-379 (2000).
    • (2000) Oncogene , vol.19 , pp. 373-379
    • De Falco, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.