The use of human cell line reporter gene-based assays in chemical toxicity testing

Toxicology in Vitro

Volumn 21, Issue 7, 2007, Pages 1233-1240

  Scrivens, Michelle ^a   Bhogal, Nirmala ^a  

^a RUSSELL AND BURCH HOUSE   (United Kingdom)

Author keywords

Animal welfare; Big Blue ; Carcinogenicity; Endocrine; Muta mouse; Mutagenicity; Reporter genes; Three Rs; Toxicity

Indexed keywords

ANDROGEN; ESTROGEN; GLUCAGON; GLUCOCORTICOID; GREEN FLUORESCENT PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 11; INTERLEUKIN 13; LUCIFERASE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; RANTES; RETINOIC ACID; RETINOID X RECEPTOR; THYROXINE;

ARTICLE; BIOASSAY; CARCINOGENICITY; CELL LINE; DNA DAMAGE; GENE MUTATION; IN VITRO STUDY; IN VIVO STUDY; MICRONUCLEUS TEST; MUTAGENICITY; NONHUMAN; REPORTER GENE; TOXICITY TESTING; TRANSGENIC ORGANISM;

ANIMAL TESTING ALTERNATIVES; ANIMALS; CARCINOGENICITY TESTS; CELL LINE, TUMOR; DNA DAMAGE; DRUG EVALUATION, PRECLINICAL; ENDOCRINE DISRUPTORS; GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; INFLAMMATION; MODELS, ANIMAL; MUTAGENICITY TESTS; RODENTIA;

ANIMALIA; RODENTIA;

EID: 35648995398     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.05.006     Document Type: Article

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