Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens. II. Further analysis of mammalian cell results, relative predictivity and tumour profiles

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 608, Issue 1, 2006, Pages 29-42

  Kirkland, David ^a   Aardema, Marilyn ^b   Müller, Lutz ^c   Hayashi, Makoto ^d  

^a UK   (United Kingdom)

^b PROCTER AND GAMBLE COMPANY   (United States)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

^d NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

Carcinogens; Chromosomal aberration; Genotoxicity; Mouse lymphoma assay; Tumour profiles

Indexed keywords

CARCINOGEN;

AMES TEST; ANIMAL CELL; ARTICLE; CARCINOGENICITY; CHROMOSOME ABERRATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORRELATION ANALYSIS; DNA ADDUCT; GENOTOXICITY; IN VITRO STUDY; IN VIVO STUDY; LYMPHOMA; MAMMAL CELL; MOUSE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; RODENT; STATISTICAL SIGNIFICANCE;

ANIMALS; CARCINOGENICITY TESTS; CARCINOGENS; CELL LINE, TUMOR; CHROMOSOME ABERRATIONS; DATABASES; EVALUATION STUDIES; FEMALE; MALE; MICE; MUTAGENICITY TESTS; PREDICTIVE VALUE OF TESTS; RATS; SENSITIVITY AND SPECIFICITY;

ANIMALIA; MAMMALIA; RODENTIA;

EID: 33747751533     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrgentox.2006.04.017     Document Type: Article

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