Application of simplified in vitro screening tests to detect genotoxicity of aristolochic acid

Food and Chemical Toxicology

Volumn 42, Issue 12, 2004, Pages 2021-2028

  Zhang, H ^a   Cifone, M A ^a   Murli, H ^a   Erexson, G L ^a   Mecchi, M S ^a   Lawlor, T E ^a  

^a UK   (United States)

Author keywords

Ames test; Aristolochic acid; Chromosomal aberrations; Genotoxicity; In vitro micronucleus; L5178Y TK+ cells; Mutation

Indexed keywords

ARISTOLOCHIC ACID;

ANIMAL CELL; ARTICLE; BACTERIAL MUTATION; BACTERIAL STRAIN; CARCINOGENICITY; CHROMOSOME ABERRATION; CONTROLLED STUDY; GENE MUTATION; GENOTOXICITY; IN VITRO STUDY; MOUSE; NONHUMAN; SCREENING TEST; STATISTICAL SIGNIFICANCE; STRUCTURAL CHROMOSOME ABERRATION; TOXICITY TESTING;

ANIMALS; ARISTOLOCHIC ACIDS; CELL LINE, TUMOR; CHO CELLS; CHROMOSOME ABERRATIONS; CRICETINAE; CULTURE MEDIA; HISTIDINE; LYMPHOMA; MICE; MICRONUCLEUS TESTS; MICROSOMES, LIVER; MUTAGENICITY TESTS; MUTAGENS; PLANT EXTRACTS; RATS; SALMONELLA TYPHIMURIUM; SUBCELLULAR FRACTIONS;

ARISTOLOCHIA; BACTERIA (MICROORGANISMS);

EID: 7044264679     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2004.07.016     Document Type: Article

References (37)

1. G. Abel, and O. Schimmer Induction of structural chromosome aberrations and sister chromatid exchanges in human lymphocytes in vitro by aristolochic acid Human Genetics 64 1983 131 133
2. B.N. Ames, J. McCann, and E. Yamasaki Methods for detecting carcinogens and mutagens with the Salmonella/Mammalian-microsome mutagenicity test Mutation Research 31 1975 347 364
3. R. Bennerman, J. Burton, and W.C. Chen Traditional Medicine and Health Care Coverage 1983 Workd Helath Organization Geneva
4. D. Bonneau, V. Thybaud, C. Melcion, F. Bouhet, and A. Cordier Optimum associations of tester strains for maximum detection of mutagenic compounds in the Ames test Mutation Research 252 1991 269 279
5. Z.-L. Chen, and D.-Y. Zhu Aristolochia alkaloids A. Brossi The Alkaloids 1987 Academic Press San Diego, CA 29 66
6. V. Ciaravino, M.J. Suto, and J.C. Theiss High capacity in vitro micronucleus assay for assessment of chromosome damage: results with quinolone/naphthyridone antibacterials Mutation Research 298 1993 227 237
7. D. Clive, W. Caspary, P.E. Kirby, R. Krehl, M. Moore, J. Mayo, and T.J. Oberly Guide for performing the mouse lymphoma assay for mammalian cell mutagenicity Mutation Research 189 1987 143 156
8. D.M. Eisenberg, R.B. Davis, S.L. Ettner, S. Appel, S. Wilkey, M. Van Rompay, and R.C. Kessler Trends in alternative medicine use in the United States, 1990-1997. Results of a follow-up national survey The Journal of the American Medical Association 280 1998 1569 1575
9. H.J. Evans Chromosomal aberrations produced by ionizing radiation International Review of Cytology 13 1962 221 321
10. H.J. Evans Cytological methods for detecting chemical mutagens A. Hollaender Chemical Mutagens, Principles and Methods for Their Detection vol. 4 1976 Plenum Press New York and London 1 29
11. N.R. Farnsworth The Napralert Database 1998 University of Illinois at Chicago Chicago, IL
12. FDA, 2001. Dietary supplements: aristolochic acid. Available from 〈 http://vm.cfsan.fda.gov/~dms/ds-bot.html 〉
13. H. Frei, F.E. Würgler, H. Juon, C.B. Hall, and U. Graf Aristolochic acid is mutagenic and recombinogenic in Drosophila genotoxicity tests Archives of Toxicology 56 1985 158 166
14. C. Furihata, Y. Yamawaki, S.S. Jin, H. Moriya, K. Kodama, T. Matsushima, T. Ishikawa, S. Takayama, and M. Nakadate Induction of unscheduled DNA synthesis in rat stomach mucosa by glandular stomach carcinogens Journal of the National Cancer Institute 72 1984 1327 1334
15. S.M. Galloway, M.J. Aardema, M. Ishidate Jr., J.L. Ivett, D.J. Kirkland, T. Morita, P. Mosesso, and T. Sofuni Report from working group on in vitro tests for chromosomal aberrations Mutation Research 312 1994 241 261
16. M.L. Garriott, J.B. Phelps, and W.P. Hoffman A protocol for the in vitro micronucleus test I. Contributions to the development of a protocol suitable for regulatory submissions for an examination of 16 chemicals with different mechanisms of action and different levels of activity Mutation Research 517 2002 123 134
17. E. Gotzl, and O. Schimmer Mutagenicity of aristolochic acid (I, II) and aristolic acid I in new YG strains in Salmonella typhimurium highly sensitive to certain mutagenic nitroarenes Mutagenesis 8 1993 17 22
18. K. Grossgebauer, H. Raettig, H. Langmaack, and R. Kuchler The induction of nonspecific resistance by lysozyme and aristolochia acid in bacterial and viral infections Zentralbl Bakteriol [orig] 213 1970 401 415
19. J.C. Hartwell Types of anticancer agents isolated from plants Cancer Treatment Reports 60 1976 1031 1067
20. S. Kevekordes, J. Spielberger, C.M. Burghaus, P. Birkenkamp, B. Zietz, P. Paufler, M. Diez, C. Bolten, and H. Dunkelblerg Micronucleus formation in human lymphocytes and the metabolically competent human hepatoma cell line Hep-G2: results with 15 naturally occurring substances Anticancer Research 21 2001 461 470
21. M. Kirsch-Volders, T. Sofuni, M. Aardema, S. Albertini, D. Eastmond, M. Fenech, M. Ishidate, E. Lorge Jr., H. Norppa, J. Surralles, W. von der Hude, and A. Wakata Report from the in vitro micronucleus assay working group Environmental and Molecular Mutagenesis 35 2000 167 172
22. TM Mouse) Mutation Research 515 2002 63 72
23. S.M. Kupchan, and R.W. Doskotch Tumor inhibitors. I. Aristolochic acid, the active principle of Aristolochia indica Journal of Medical Pharmacology and Chemistry 5 1962 657 658
24. S.M. Kupchan, and J.J. Merianos The isolation and structural elucidation of novel derivatives of aristolochic acid from Aristolochia indica Journal of Organic Chemistry 33 1968 3735 3738
25. P. Maier, H. Schawalder, and B. Weibel Low oxygen tension, as found in tissues in vivo, alters the mutagenic activity of aristolochic acid I and II in primary fibroblast-like rat cells in vitro Environmental and Molecular Mutagenesis 10 1987 275 284
26. D.M. Maron, and B.N. Ames Revised methods for the Salmonella mutagenicity test Mutation Research 113 1983 173 215
27. U. Meng, W. Lang, and J.A. Poch The carcinogenic action of aristolochic acid Archive of Toxicology 51 1982 107 119
28. J.R. Mose The effect of aristolochic acid on the development of methylcholanthrene tumors in mice Osterreichische Kneipp-Magazin 2 1975 151 153
29. J.R. Mose, D. Stunzner, M. Zirm, C. Egger-Bussing, and F. Schmalzl Effect of aristolochic acid on herpes simples infection of the rabbit eye Arzneimittelforschung 30 1980 1571 1573
30. J.M. Pezzuto, S.M. Swanson, W. Mar, C.-T. Che, G.A. Cordell, and H.H.S. Fong Evaluation of the mutagenic and cytostatic potential of aristolochic acid (3,4-methylenedioxy-8-methoxy-10-nitrophenanthrene-1-carboxylic acid) and several of its derivatives Mutation Research 206 1988 447 454
31. G. Robisch, O. Schimmer, and W. Gggelmann Aristolochic acid is a direct mutagen in Salmonella typhimurium Mutation Research 105 1982 201 204
32. H.H. Schmeiser, B.L. Pool, and M. Wiessler Mutagenicity of the two main components of commercially available carcinogenic aristolochic acid in Salmonella typhimurium Cancer Letter 23 1984 97 101
33. Z.X. Shen Recent research and developments in traditional Chinese medicine in China Report of the Third Meeting of Directors of WHO Collaborating Centres for Traditional Medicine 1996 World Health Organization Geneva
34. A.K. Thakur, K.J. Berry, and P.W. Mielke Jr. A Fortran program for testing trend and homogeneity in proportions Computer Programs in Biomedicine 19 1985 229 233
35. L.H. Tsai, H.J. Liu, C.P. Yang, and C. Chang Inactivation of Formosan snake venoms in vitro by the crude extract of Aristolochia radix Taiwan Yi Xue Hui Za Zhi 74 1975 352 360
36. W. von der Huge, S. Kalweit, G. Engelhardt, S. McKiernan, P. Kasper, R. Slacik-Erben, H.G. Miltenburger, N. Honarvar, R. Fahrig, B. Gorlitz, S. Albertini, S. Kirchner, D. Utesch, F. Potter-Locher, H. Stopper, and S. Madle In vitro micronucleus assay with Chinese hamster V79 cells--results of a collaborative study with in situ exposure to 26 chemical substances Mutation Research 468 2000 137 163
37. B. Xing, L. Chen, L. Zhou, L. Jiang, and F. Liu Experimental study on the carcinogenicity of aristolochic acid Guangxi Yixue 4 1982 118 121