New fluorescence techniques for high-throughput drug discovery

Current Pharmaceutical Biotechnology

Volumn 4, Issue 6, 2003, Pages 463-476

  Jager S ^a   Brand, L ^a   Eggeling, C ^a,b  

^a Evotec OAI   (Germany)

^b MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

Artifact correction; Confocal optics; FCS; FIDA; Fluorescence lifetime; High throughput screening; Single molecule detection; Time resolved anisotrophy

Indexed keywords

BIOPOLYMER; DRUG; PROPRANOLOL; PROTEIN;

ACCURACY; ALGORITHM; ANALYTIC METHOD; ANISOTROPY; ARTIFACT; AUTOFLUORESCENCE; CHEMISTRY; CLINICAL PRACTICE; CONFOCAL MICROSCOPY; DRUG ACTIVITY; DRUG DESIGN; DRUG DETERMINATION; DRUG RESEARCH; DRUG SCREENING; DRUG TARGETING; FLUORESCENCE ANALYSIS; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIGH THROUGHPUT SCREENING; INFORMATION PROCESSING; INSTRUMENTATION; INTERMETHOD COMPARISON; MACROMOLECULE; MEDICAL GENETICS; MEDICAL INSTRUMENTATION; METHODOLOGY; MOLECULAR LIBRARY; PHOTOCHEMICAL QUENCHING; REPRODUCIBILITY; REVIEW; SENSITIVITY ANALYSIS; SENSITIVITY AND SPECIFICITY; SPECTROFLUOROMETRY; STATISTICAL ANALYSIS; TIME;

ALGORITHMS; ARTIFACTS; BIOPOLYMERS; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; FLUORESCENCE RESONANCE ENERGY TRANSFER; MACROMOLECULAR SUBSTANCES; PHARMACEUTICAL PREPARATIONS; PROTEINS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, FLUORESCENCE; STATISTICS;

EID: 0348155858     PISSN: 13892010     EISSN: None     Source Type: Journal    
DOI: 10.2174/1389201033377382     Document Type: Review

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