Mutation of Asp171 and Asp262 of the chemokine receptor CXCR4 impairs its coreceptor function for human immunodeficiency virus-1 entry and abrogates the antagonistic activity of AMD3100

Molecular Pharmacology

Volumn 60, Issue 1, 2001, Pages 164-173

  Hatse, Sigrid ^a   Princen, Katrien ^a   Gerlach, Lars Ole ^b   Bridger, Gary ^c   Henson, Geoffrey ^c   De Clercq, Erik ^a   Schwartz, Thue W ^b   Schols, Dominique ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c GENZYME CORPORATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,1' [1,4 PHENYLENEBIS(METHYLENE)]BIS(1,4,8,11 TETRAAZACYCLOTETRADECANE); ALANINE; ASPARAGINE; CALCIUM ION; CHEMOKINE RECEPTOR CXCR4; ENVELOPE PROTEIN; STROMAL CELL DERIVED FACTOR 1;

AMINO ACID SUBSTITUTION; ARTICLE; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CONTROLLED STUDY; DRUG ACTIVITY; GENE MUTATION; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN;

EID: 0034954455     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.60.1.164     Document Type: Article

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