Small amino acid changes in the V3 loop of human immunodeficiency virus type 2 determines the coreceptor usage for CXCR4 and CCr5

Virology

Volumn 264, Issue 1, 1999, Pages 237-243

  Isaka, Yoshitaka ^a   Sato, Akihiko ^a   Miki, Shigeru ^a   Kawauchi, Shinobu ^a   Sakaida, Hitoshi ^b   Hori, Toshiyuki ^b   Uchiyama, Takashi ^b   Adachi, Akio ^c   Hayami, Masanori ^b   Fujiwara, Tamio ^a   Yoshie, Osamu ^d  

^a SHIONOGI AND CO LTD   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKUSHIMA   (Japan)

^d KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4; GLYCOPROTEIN GP 120;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; AMINO ACID COMPOSITION; ARTICLE; CONTROLLED STUDY; HELA CELL; HELPER CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; LONG TERMINAL REPEAT; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; PSEUDOMONAS PHAGE GH-1; RNA VIRUSES;

EID: 0033544335     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1999.0006     Document Type: Article

References (25)

1. Adachi A., Gendelman H. E., Koenig S., Folks T., Willey R., Rabson A., Martin M. A. Production of acquired immunodeficiency syndrome-associated retrovirus in human and non-human cells transfected with an infectious molecular clone. J. Virol. 59:1986;284-291.
2. Bieniasz P. D., Fridell R. A., Aramori I., Ferguson S. S. G., Caron M. G., Cullen B. R. HIV-1 induced cell fusion is mediated by multiple regions within both the viral envelope and the CCR5 coreceptor. EMBO J. 16:1997;2599-2609.
3. Bron R., Klasse P. J., Wilkinson D., Clapham P. R., Pelchen-Matthews A., Power C., Wells T. N. C., Kim J., Peiper S. C., Hoxie J. A., Marsh M. Promiscuous use of CC and CXC chemokine receptors in cell-to-cell fusion mediated by a human immunodeficiency virus type 2 envelope protein. J. Virol. 71:1997;8405-8415.
4. Cairns J. S., D'Souza M. P. Chemokines and HIV-1 second receptors: the therapeutic connection. Nat. Med. 4:1998;563-568.
5. Chen Z., Zhou P., Ho D. D., Landau N. R., Marx P. A. Genetically divergent strains of simian immunodeficiency virus use CCR5 as a coreceptor for entry. J. Virol. 71:1997;2705-2714.
6. Choe H., Farzan M., Sun Y., Sullivan N., Rollins B., Ponath P. D., Wu L., Mackay C. R., LaRosa G., Newman W., Gerard N., Gerard C., Sodroski J. The β-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates. Cell. 85:1996;1135-1148.
7. Clavel F., Guetard D., Brun-Vezinet F., Chamaret S., Rey M. -A., Santos-Ferreira M. O., Laurent A. G., Dauguet C., Katlama C., Rouzioux C., Klatzmann D., Champalimaud J. L., Montagnier L. Isolation of a new human retrovirus from west African patients with AIDS. Science. 233:1986;343-346.
8. Cocchi F., DeVico A. L., Garzino-Demo A., Cara A., Gallo R. C., Lusso P. The V3 domain of the HIV-1 gp120 envelop glycoprotein is critical for chemokine-mediated blockade of infection. Nat. Med. 2:1996;1244-1247.
9. Deng H. K., Unutmaz D., KewalRamani V. N., Littman D. R. Expression cloning of new receptors used by simian and human immunodeficiency viruses. Nature. 388:1997;296-300.
10. Endres M. J., Clapham P. R., Marsh M., Ahuja M., Turner J. D., McKnight A., Thomas J. F., Stoebenau-Haggarty B., Choe S., Vance P. J., Wells T. N. C., Power C. A., Sutterwala S. S., Doms R. W., Landau N. R., Hoxie J. A. CD4-independent infection by HIV-2 is mediated by fusin/CXCR4. Cell. 87:1996;745-756.
11. Hasegawa A., Tsujimoto H., Maki N., Ishikawa K., Miura T., Fukasawa M., Miki K., Hayami M. Genomic divergence of HIV-2 from Ghana. 1989. AIDS Res. Hum. Retroviruses. 5:1989;593-604.
12. Hill C. M., Deng H., Unutmaz D., KewalRamani V. N., Bastiani L., Gorny M. K., Zolla-Pazner S., Littman D. R. Envelope glycoproteins from human immunodeficiency virus types 1 and 2 and simiam immunodeficiency virus can use human CCR5 as a coreceptor for viral entry and make direct CD4-dependent interactions with this chemokine receptor. J. Virol. 71:1997;6296-6304.
13. Hori T., Sakaida H., Sato A., Nakajima T., Shida H., Yoshie O., Uchiyama T. Detection and delineation of CXCR-4 (fusin) as an entry and fusin cofactor for T-tropic HIV-1 by three different monoclonal antibodies. J. Immunol. 160:1998;180-188.
14. Kawamura M., Shimano R., Ogasawara T., Inubushi R., Amano K., Akari H., Adachi A. Mapping the genetic determinants of human immunodeficiency virus type 2 for cell tropism and replication efficiency. Arch. Virol. 143:1998;1-9.
15. Kitaura M., Nakajima T., Imai T., Harada S., Combadiere C., Tiffany H. L., Murphy P. M., Yoshie O. Molecular cloning of human eotaxin, an eosinophil-selective CC chemokine, and identification of a specific eosinophil eotaxin receptor, CC chemokine receptor 3. J. Biol. Chem. 271:1996;7725-7730.
16. Marcon L., Choe H., Martin K. A., Farzan M., Ponath P. D., Wu L., Newman W., Gerard N., Gerard C., Sodroski J. Utilization of C-C chemokine receptor 5 by the envelope glycoproteins of a pathogenic simian immunodeficiency virus, SIVmac 239. J. Virol. 71:1997;2522-2527.
17. McKnight A., Dittmar M. T., Moniz-Periera J., Ariyoshi K., Reeves J. D., Hibbitts S., Whitby D., Aarons E., Proudfoot A. E. I., Whittle H., Clapham P. R. A broad range of chemokine receptors are used by primary isolates of human immunodeficiency virus type 2 as coreceptors with CD4. J. Virol. 72:1998;4065-4071.
18. Morner A., Bjorndal A., Albert J., KewalRamani V. N., Littman D. R., Inoue R., Thorstensson R., Fenyo E. M., Bjorling E. Primary human Immunodeficiency virus type 2 (HIV-2) isolates, like HIV-1 isolates, frequently use CCR5 but show promiscuity in coreceptor usage. J. Virol. 73:1999;2343-2349.
19. Reeves J. D., McKnight A., Potempa S., Simmons G., Gray P. W., Power C. A., Wells T., Weiss R. A., Talbot S. J. CD4-independent infection by HIV-2 (ROD/B): Use of the 7-transmembrane receptors CXCR-4, CCR-3, and V28 for entry. Virology. 231:1997;130-134.
20. Ross T. M., Bieniasz P. D., Cullen B. R. Role of chemokine receptors in HIV-1 infection and pathogenesis. Adv. Virus Res. 52:1999;233-267.
21. Sato A., Kodama M., Abe K., Miki S., Nishimura M., Suyama A., Ogata M., Toyoda T., Sugimoto H., Yoshie O., Fujiwara T. A simple and rapid method for preliminary evaluation of in vivo efficacy of anti-HIV compounds in mice. Antiviral Res. 27:1995;151-163.
22. Shibata R., Miura T., Hayami M., Ogawa K., Sakai H., Kiyomasu T., Ishimoto A., Adachi A. Mutation analysis of the human immunodeficiency virus type 2 (HIV-2) genome in relation to HIV-1 and Simian Immunodeficiency virus SIV AGM. J. Virol. 64:1990;742-747.
23. Shioda T., Levy J. A., Cheng-Meyer C. Small amino acid changes in the V3 hypervariable region of gp120 can affect the T-cell-line and macrophage tropism of human immunodeficiency virus type 1. Proc. Natl. Acad. Sci. USA. 89:1992;9434-9438.
24. Sol N., Ferchal F., Braun J., Pleskoff O., Treboute C., Ansart I., Alizon M. Usage of the coreceptors CCR-5, CCR-3, and CXCR-4 by primary and cell line-adapted human immunodeficiency virus type 2. J. Virol. 71:1997;8237-8244.
25. Tachibana K., Nakajima T., Sato A., Igarashi K., Shida H., Iizawa H., Yoshida N., Yoshie O., Kishimoto T., Nagasawa T. CXCR-4/fusin is not a species-specific barrier in murine cells for HIV-1 entry. J. Exp. Med. 185:1997;1865-1870.