Optimal protein library design using recombination or point mutations based on sequence-based scoring functions

Protein Engineering, Design and Selection

Volumn 20, Issue 8, 2007, Pages 361-373

  Pantazes, Robert J ^a   Saraf, Manish C ^a   Maranas, Costas D ^a  

^a PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Hybrid scoring method; Protein engineering; Protein library optimization

Indexed keywords

BENCHMARKING; DNA SEQUENCES; HYDROPHOBICITY; MOLECULAR INTERACTIONS; MUTAGENESIS;

HYBRID SCORING METHODS; PROTEIN ENGINEERING; PROTEIN LIBRARY OPTIMIZATION;

PROTEINS;

AMINO ACID; CYTOCHROME P450; HYBRID PROTEIN;

ARTICLE; GENE CONSTRUCT; GENE FUNCTION; GENE LIBRARY; GENETIC RECOMBINATION; HYDROPHOBICITY; POINT MUTATION; PRIORITY JOURNAL; PROTEIN INTERACTION; QUANTITATIVE ANALYSIS; SCORING SYSTEM; SEQUENCE ANALYSIS; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO ACIDS; BENCHMARKING; COMBINATORIAL CHEMISTRY TECHNIQUES; COMPUTATIONAL BIOLOGY; CONSENSUS SEQUENCE; HYDROPHOBICITY; MODELS, THEORETICAL; MOLECULAR SEQUENCE DATA; POINT MUTATION; PROTEIN ENGINEERING; PROTEINS; RECOMBINATION, GENETIC; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 34548803632     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzm030     Document Type: Article

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