Growth factor engineering by degenerate homoduplex gene family recombination

Nature Biotechnology

Volumn 20, Issue 12, 2002, Pages 1246-1250

  Coco, Wayne M ^a,b,g   Encell, Lance P ^a,b   Levinson, William E ^a   Crist, Michael J ^a,c   Loomis, A Katrina ^a,b   Licato, Laura L ^a,d   Arensdorf, Joseph J ^a,e   Sica, Nicole ^a,b   Pienkos, Philip T ^a,f   Monticello, Daniel J ^a,g  

^a Enchira Biotechnology Corporation   (United States)

^b Tanox Biosystems Inc   (United States)

^c LEXICON PHARMACEUTICALS INC   (United States)

^d Isolagen Inc   (United States)

^e BAKER PETROLITE   (United States)

^f Fermentation Developments   (United States)

^g Molecular Logix Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLONING; DNA; GENES; GROWTH KINETICS; PROTEINS;

POLYMORPHISMS;

BIOTECHNOLOGY;

CHIMERIC PROTEIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; OLIGONUCLEOTIDE; PROTEIN TYROSINE KINASE; RECEPTOR BLOCKING AGENT; RECOMBINANT DNA; TAQ POLYMERASE; PEPTIDE LIBRARY; RECOMBINANT PROTEIN;

AGONIST; ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA LIBRARY; DNA RECOMBINATION; DNA SEQUENCE; MOLECULAR CLONING; MOUSE; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; RECEPTOR AFFINITY; WOUND HEALING; ANIMAL; CLASSIFICATION; GENETIC RECOMBINATION; GENETICS; HORSE; HUMAN; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; RAT; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SWINE;

ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; EPIDERMAL GROWTH FACTOR; HORSES; HUMANS; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE LIBRARY; PROTEIN ENGINEERING; RATS; RECOMBINANT PROTEINS; RECOMBINATION, GENETIC; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; SWINE;

EID: 0036901301     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt757     Document Type: Article

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