-
1
-
-
0028050350
-
Rapid evolution of a protein in vitro by DNA shuffling
-
Stemmer WP. Rapid evolution of a protein in vitro by DNA shuffling. Nature 1994;370:389-391.
-
(1994)
Nature
, vol.370
, pp. 389-391
-
-
Stemmer, W.P.1
-
3
-
-
1642329356
-
Computational challenges in combinatorial library design for protein engineering
-
Moore GL, Maranas CD. Computational challenges in combinatorial library design for protein engineering. AICHE J 2004;50:262-272.
-
(2004)
AICHE J
, vol.50
, pp. 262-272
-
-
Moore, G.L.1
Maranas, C.D.2
-
4
-
-
0036901312
-
Synthetic shuffling expands functional protein diversity by allowing amino acids to recombine independently
-
Ness JE, Kim S, Gottman A, Pak R, Krebber A, Borchert TV, Govindarajan S, Mundorff EC, Minshull J. Synthetic shuffling expands functional protein diversity by allowing amino acids to recombine independently. Nat Biotechnol 2002;20:1251-1255.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 1251-1255
-
-
Ness, J.E.1
Kim, S.2
Gottman, A.3
Pak, R.4
Krebber, A.5
Borchert, T.V.6
Govindarajan, S.7
Mundorff, E.C.8
Minshull, J.9
-
5
-
-
0036901301
-
Growth factor engineering by degenerate homoduplex gene family recombination
-
Coco WM, Encell LP, Levinson WE, Crist MJ, Loomis AK, Licato LL, Arensdorf JJ, Sica N, Pienkos PT, Monticello DJ. Growth factor engineering by degenerate homoduplex gene family recombination. Nat Biotechnol 2002;20:1246-1250.
-
(2002)
Nat Biotechnol
, vol.20
, pp. 1246-1250
-
-
Coco, W.M.1
Encell, L.P.2
Levinson, W.E.3
Crist, M.J.4
Loomis, A.K.5
Licato, L.L.6
Arensdorf, J.J.7
Sica, N.8
Pienkos, P.T.9
Monticello, D.J.10
-
6
-
-
0038799745
-
General method for sequence-independent site-directed chimeragenesis
-
Hiraga K, Arnold FH. General method for sequence-independent site-directed chimeragenesis. J Mol Biol 2003;330:287-296.
-
(2003)
J Mol Biol
, vol.330
, pp. 287-296
-
-
Hiraga, K.1
Arnold, F.H.2
-
7
-
-
0041765676
-
User-friendly algorithms for estimating completeness and diversity in randomized protein-encoding libraries
-
Patrick WM, Firth AE, Blackburn JM. User-friendly algorithms for estimating completeness and diversity in randomized protein-encoding libraries. Protein Eng 2003;16:451-457.
-
(2003)
Protein Eng
, vol.16
, pp. 451-457
-
-
Patrick, W.M.1
Firth, A.E.2
Blackburn, J.M.3
-
8
-
-
0037716688
-
Synthetic gene libraries: In search of the optimal diversity
-
Ostermeier M. Synthetic gene libraries: in search of the optimal diversity. Trends Biotechnol 2003;21:244-247.
-
(2003)
Trends Biotechnol
, vol.21
, pp. 244-247
-
-
Ostermeier, M.1
-
9
-
-
0035928796
-
Backbone dynamics in dihydrofolate reductase complexes: Role of loop flexibility in the catalytic mechanism
-
Osborne MJ, Schnell J, Benkovic SJ, Dyson HJ, Wright PE. Backbone dynamics in dihydrofolate reductase complexes: role of loop flexibility in the catalytic mechanism. Biochemistry 2001;40:9846-9859.
-
(2001)
Biochemistry
, vol.40
, pp. 9846-9859
-
-
Osborne, M.J.1
Schnell, J.2
Benkovic, S.J.3
Dyson, H.J.4
Wright, P.E.5
-
10
-
-
0038810233
-
Correlated motion and the effect of distal mutations in dihydrofolate reductase
-
Rod TH, Radkiewicz JL, Brooks CL 3rd. Correlated motion and the effect of distal mutations in dihydrofolate reductase. Proc Natl Acad Sci USA 2003;100:6980-6985.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 6980-6985
-
-
Rod, T.H.1
Radkiewicz, J.L.2
Brooks III, C.L.3
-
11
-
-
0031015737
-
Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: Crystallographic evidence
-
Sawaya MR, Kraut J. Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry 1997;36:586-603.
-
(1997)
Biochemistry
, vol.36
, pp. 586-603
-
-
Sawaya, M.R.1
Kraut, J.2
-
12
-
-
0037022683
-
Network of coupled promoting motions in enyzme catalysis
-
Agarwal PK, Billeter SR, Rajagopalan PT, Benkovic SJ, Hammes-Schiffer S. Network of coupled promoting motions in enyzme catalysis. Proc Natl Acad Sci USA 2002;99:2794-2799.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 2794-2799
-
-
Agarwal, P.K.1
Billeter, S.R.2
Rajagopalan, P.T.3
Benkovic, S.J.4
Hammes-Schiffer, S.5
-
14
-
-
1442286044
-
Using a residue clash map to functionally characterize protein recombination hybrids
-
Saraf MC, Maranas CD. Using a residue clash map to functionally characterize protein recombination hybrids. Protein Eng 2003;16:1025-1034.
-
(2003)
Protein Eng
, vol.16
, pp. 1025-1034
-
-
Saraf, M.C.1
Maranas, C.D.2
-
15
-
-
0037627753
-
Identifying residue-residue clashes in protein hydrids by using a second-order mean-field approach
-
Moore GL, Maranas CD. Identifying residue-residue clashes in protein hydrids by using a second-order mean-field approach. Proc Natl Acad Sci USA 2003;100:5091-5096.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 5091-5096
-
-
Moore, G.L.1
Maranas, C.D.2
-
16
-
-
0036289574
-
Protein building blocks preserved by recombination
-
Voigt CA, Martinez C, Wang ZG, Mayo SL, Arnold FH. Protein building blocks preserved by recombination. Nat Struct Biol 2002;9:553-558.
-
(2002)
Nat Struct Biol
, vol.9
, pp. 553-558
-
-
Voigt, C.A.1
Martinez, C.2
Wang, Z.G.3
Mayo, S.L.4
Arnold, F.H.5
-
17
-
-
0038731100
-
Library analysis of SCHEME-guided protein recombination
-
Meyer MM, Silberg JJ, Voigt CA, Endelman JB, Mayo SL, Wang ZG, Arnold FH. Library analysis of SCHEME-guided protein recombination. Protein Sci 2003;12:1686-1693.
-
(2003)
Protein Sci
, vol.12
, pp. 1686-1693
-
-
Meyer, M.M.1
Silberg, J.J.2
Voigt, C.A.3
Endelman, J.B.4
Mayo, S.L.5
Wang, Z.G.6
Arnold, F.H.7
-
19
-
-
0042767572
-
Using multiple sequence correlation analysis to characterize functionally important protein regions
-
Saraf MC, Moore GL, Maranas CD. Using multiple sequence correlation analysis to characterize functionally important protein regions. Protein Eng 2003;16:397-406.
-
(2003)
Protein Eng
, vol.16
, pp. 397-406
-
-
Saraf, M.C.1
Moore, G.L.2
Maranas, C.D.3
-
20
-
-
0029913807
-
An evolutionary trace method defines binding surfaces common to protein families
-
Lichtarge O, Bourne HR, Cohen FE. An evolutionary trace method defines binding surfaces common to protein families. J Mol Biol 1996;257:342-358.
-
(1996)
J Mol Biol
, vol.257
, pp. 342-358
-
-
Lichtarge, O.1
Bourne, H.R.2
Cohen, F.E.3
-
21
-
-
0030623398
-
An inverse correlation between loop length and stability in a four-Helix-bundle protein
-
Nagi AD, Regan L. An inverse correlation between loop length and stability in a four-helix-bundle protein. Fold Des 1997;2:67-75.
-
(1997)
Fold des
, vol.2
, pp. 67-75
-
-
Nagi, A.D.1
Regan, L.2
-
22
-
-
0033052969
-
A hierarchical approach to protein molecular evolution
-
Bogarad LD, Deem MW. A hierarchical approach to protein molecular evolution. Proc Natl Acad Sci USA 1999;96:2591-2595.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 2591-2595
-
-
Bogarad, L.D.1
Deem, M.W.2
-
23
-
-
0016619730
-
Improved linear integer programming formulations of nonlinear integer problems
-
Glover F. Improved linear integer programming formulations of nonlinear integer problems. Manage Sci 1975;22:455-460.
-
(1975)
Manage Sci
, vol.22
, pp. 455-460
-
-
Glover, F.1
-
24
-
-
9144257886
-
The Pfam protein families database
-
Bateman A, Coin L, Durbin R, Finn RD, Holich V, Griffiths-Jones S, Khanna A, Marshall M, Moxon S, Sonnhammer EL, Studholme DJ, Yeats C, Eddy SR. The Pfam protein families database. Nucleic Acids Res 2004;32(Database issue)D138-D141.
-
(2004)
Nucleic Acids Res
, vol.32
, Issue.DATABASE ISSUE
-
-
Bateman, A.1
Coin, L.2
Durbin, R.3
Finn, R.D.4
Holich, V.5
Griffiths-Jones, S.6
Khanna, A.7
Marshall, M.8
Moxon, S.9
Sonnhammer, E.L.10
Studholme, D.J.11
Yeats, C.12
Eddy, S.R.13
-
27
-
-
0038752617
-
Computational design of receptor and sensor proteins with novel functions
-
Looger LL, Dwyer MA, Smith JJ, Hellinga HW. Computational design of receptor and sensor proteins with novel functions. Nature 2003;423:185-190.
-
(2003)
Nature
, vol.423
, pp. 185-190
-
-
Looger, L.L.1
Dwyer, M.A.2
Smith, J.J.3
Hellinga, H.W.4
-
28
-
-
3042655537
-
Computational design of a biologically active enzyme
-
Dwyer MA, Looper LL, Hellinga HW. Computational design of a biologically active enzyme. Science 2004;304:1967-1971.
-
(2004)
Science
, vol.304
, pp. 1967-1971
-
-
Dwyer, M.A.1
Looper, L.L.2
Hellinga, H.W.3
-
29
-
-
0345306764
-
Design of a novel globular protein fold with atomic-level accuracy
-
Kuhlman B, Dantas G, Ireton GC, Varani G, Stoddard BL, Baker D. Design of a novel globular protein fold with atomic-level accuracy. Science 2003;302:1364-1368.
-
(2003)
Science
, vol.302
, pp. 1364-1368
-
-
Kuhlman, B.1
Dantas, G.2
Ireton, G.C.3
Varani, G.4
Stoddard, B.L.5
Baker, D.6
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