-
1
-
-
0036137987
-
Understanding autoimmune diabetes: insights from mouse models
-
Adorini L., Gregori S., and Harrison L.C. Understanding autoimmune diabetes: insights from mouse models. Trends. Mol. Med. 8 (2002) 31-38
-
(2002)
Trends. Mol. Med.
, vol.8
, pp. 31-38
-
-
Adorini, L.1
Gregori, S.2
Harrison, L.C.3
-
2
-
-
0033001488
-
The NOD mouse model of type 1 diabetes: as good as it gets?
-
Atkinson M.A., and Leiter E.H. The NOD mouse model of type 1 diabetes: as good as it gets?. Nat. Med. 5 (1999) 601-604
-
(1999)
Nat. Med.
, vol.5
, pp. 601-604
-
-
Atkinson, M.A.1
Leiter, E.H.2
-
3
-
-
0026646694
-
The murine autoimmune diabetes model: NOD and related strains
-
Kikutani H., and Makino S. The murine autoimmune diabetes model: NOD and related strains. Adv. Immunol. 51 (1992) 285-322
-
(1992)
Adv. Immunol.
, vol.51
, pp. 285-322
-
-
Kikutani, H.1
Makino, S.2
-
4
-
-
0031010513
-
Identification of immunogenic epitopes of GAD65 presented by Ag7 in non-obese diabetic mice
-
Chao C.C., and McDevitt H.O. Identification of immunogenic epitopes of GAD65 presented by Ag7 in non-obese diabetic mice. Immunogenetics 46 (1997) 29-34
-
(1997)
Immunogenetics
, vol.46
, pp. 29-34
-
-
Chao, C.C.1
McDevitt, H.O.2
-
5
-
-
0033553645
-
Control of autoimmune diabetes in NOD mice by GAD expression or suppression in cells
-
Ji-Won Y., Chang-Soon Y., Hye-Won L., Huang Q.Q., Kang Y., Pyun K.H., Hirasawa K., Sherwin R.S., and Hee-Sook J. Control of autoimmune diabetes in NOD mice by GAD expression or suppression in cells. Science 284 (1999) 1183-1187
-
(1999)
Science
, vol.284
, pp. 1183-1187
-
-
Ji-Won, Y.1
Chang-Soon, Y.2
Hye-Won, L.3
Huang, Q.Q.4
Kang, Y.5
Pyun, K.H.6
Hirasawa, K.7
Sherwin, R.S.8
Hee-Sook, J.9
-
6
-
-
0027368141
-
Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes
-
Kaufman D.L., Clare-Salzer M., Tian J., Forsthuber T., Ting G.S.P., Robinson P., Atkinson M.A., Sercarz E., Tobin A., and Lehmann P.L. Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes. Nature 366 (1993) 69-72
-
(1993)
Nature
, vol.366
, pp. 69-72
-
-
Kaufman, D.L.1
Clare-Salzer, M.2
Tian, J.3
Forsthuber, T.4
Ting, G.S.P.5
Robinson, P.6
Atkinson, M.A.7
Sercarz, E.8
Tobin, A.9
Lehmann, P.L.10
-
7
-
-
0030175329
-
T cells with multiple fine specificities are used by non-obese diabetic (NOD) mice in the response to GAD (524-543)
-
Quinn A., and Sercarz E.E. T cells with multiple fine specificities are used by non-obese diabetic (NOD) mice in the response to GAD (524-543). J. Autoimmun. 9 (1996) 365-370
-
(1996)
J. Autoimmun.
, vol.9
, pp. 365-370
-
-
Quinn, A.1
Sercarz, E.E.2
-
8
-
-
0027908753
-
Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice
-
Tisch R., Yang X.D., Singer S.M., Liblau R.S., Fugger L., and McDevitt H.O. Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature 366 (1993) 72-75
-
(1993)
Nature
, vol.366
, pp. 72-75
-
-
Tisch, R.1
Yang, X.D.2
Singer, S.M.3
Liblau, R.S.4
Fugger, L.5
McDevitt, H.O.6
-
9
-
-
0036569428
-
Gene transfer of Ig-fusion proteins into B cells prevents and treats autoimmune diseases
-
Melo M., Qian J.H., EL-Amine M., Agarwal R.K., Soukhareva N., Kang Y., and Scott D.W. Gene transfer of Ig-fusion proteins into B cells prevents and treats autoimmune diseases. J. Immunol. 168 (2002) 4788-4795
-
(2002)
J. Immunol.
, vol.168
, pp. 4788-4795
-
-
Melo, M.1
Qian, J.H.2
EL-Amine, M.3
Agarwal, R.K.4
Soukhareva, N.5
Kang, Y.6
Scott, D.W.7
-
10
-
-
5444221869
-
Retroviral delivery of GAD-IgG fusion construct induces tolerance and modulates diabetes: a role for CD4+ regulatory T cells and TGF-β?
-
Song L., Wang J., Wang R., Yu M., Sun Y., Han G., Li Y., Qian J., Scott D.W., Kang Y., Soukhareva N., and Shen B. Retroviral delivery of GAD-IgG fusion construct induces tolerance and modulates diabetes: a role for CD4+ regulatory T cells and TGF-β?. Gene. Ther. 11 (2004) 1487-1496
-
(2004)
Gene. Ther.
, vol.11
, pp. 1487-1496
-
-
Song, L.1
Wang, J.2
Wang, R.3
Yu, M.4
Sun, Y.5
Han, G.6
Li, Y.7
Qian, J.8
Scott, D.W.9
Kang, Y.10
Soukhareva, N.11
Shen, B.12
-
11
-
-
4344586383
-
Advances in asthma, allergy and immunology series 2004: basic and clinical immunology
-
Chinen J., and Shearer W.T. Advances in asthma, allergy and immunology series 2004: basic and clinical immunology. J. Allergy Clin. Immunol. 114 (2004) 398-405
-
(2004)
J. Allergy Clin. Immunol.
, vol.114
, pp. 398-405
-
-
Chinen, J.1
Shearer, W.T.2
-
12
-
-
0041735102
-
Regulatory T cells control the development of allergic disease and asthma
-
Umetsu D.T., Akbari O., and Dekruyff R.H. Regulatory T cells control the development of allergic disease and asthma. J. Allergy Clin. Immunol. 112 (2003) 480-487
-
(2003)
J. Allergy Clin. Immunol.
, vol.112
, pp. 480-487
-
-
Umetsu, D.T.1
Akbari, O.2
Dekruyff, R.H.3
-
13
-
-
0037323510
-
Immunotherapy of allergic disease
-
Frew A.J. Immunotherapy of allergic disease. J. Allergy Clin. Immunol. 111 (2003) s712-s719
-
(2003)
J. Allergy Clin. Immunol.
, vol.111
-
-
Frew, A.J.1
-
14
-
-
1542511733
-
Immunologic influences on allergy and the Th1/Th2 balance
-
Romagnani S. Immunologic influences on allergy and the Th1/Th2 balance. J. Allergy Clin. Immunol. 113 (2004) 395-400
-
(2004)
J. Allergy Clin. Immunol.
, vol.113
, pp. 395-400
-
-
Romagnani, S.1
-
15
-
-
0037385330
-
Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
-
Fontenot J.D., Gavin M.A., and Rudensky A.Y. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat. Immunol. 4 (2003) 330-336
-
(2003)
Nat. Immunol.
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
16
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor Foxp3
-
Hori S., Nomura T., and Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science 299 (2003) 1057-1061
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
17
-
-
0037385314
-
An essential role for Scurfin in CD4+CD25+ T regulatory cells
-
Khattri R., Cox T., Yasayko S.A., and Ramsdell F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat. Immunol. 4 (2003) 337-342
-
(2003)
Nat. Immunol.
, vol.4
, pp. 337-342
-
-
Khattri, R.1
Cox, T.2
Yasayko, S.A.3
Ramsdell, F.4
-
18
-
-
0033523607
-
An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
-
Asseman C., Mauze S., Leach M.W., Coffman R.L., and Powrie F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. 190 (1999) 995-1004
-
(1999)
J. Exp. Med.
, vol.190
, pp. 995-1004
-
-
Asseman, C.1
Mauze, S.2
Leach, M.W.3
Coffman, R.L.4
Powrie, F.5
-
19
-
-
2942642383
-
In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes
-
Tang Q., Henriksen K.J., Bi M., Finger E.B., Szot G., Ye J., Masteller E.L., McDevitt H., Bonyhadi M., and Bluestone J.A. In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes. J. Exp. Med. 199 (2004) 1455-1465
-
(2004)
J. Exp. Med.
, vol.199
, pp. 1455-1465
-
-
Tang, Q.1
Henriksen, K.J.2
Bi, M.3
Finger, E.B.4
Szot, G.5
Ye, J.6
Masteller, E.L.7
McDevitt, H.8
Bonyhadi, M.9
Bluestone, J.A.10
-
20
-
-
0019227125
-
Haptens bound to self IgG induce immunologic tolerance, while when couped to syngeneic spleen cells they induce immune suppression
-
Borel Y. Haptens bound to self IgG induce immunologic tolerance, while when couped to syngeneic spleen cells they induce immune suppression. Immunol. Rev. 50 (1980) 71-104
-
(1980)
Immunol. Rev.
, vol.50
, pp. 71-104
-
-
Borel, Y.1
-
21
-
-
0033927572
-
Retroviral gene therapy with an immunoglobulin-antigen fusion construct protects from experimental autoimmune uveitis
-
Agarwal R.K., Kang Y., Zambidis E., Scott D.W., Chan C.C., and Caspi R.R. Retroviral gene therapy with an immunoglobulin-antigen fusion construct protects from experimental autoimmune uveitis. J. Clin. Invest. 106 (2000) 245-252
-
(2000)
J. Clin. Invest.
, vol.106
, pp. 245-252
-
-
Agarwal, R.K.1
Kang, Y.2
Zambidis, E.3
Scott, D.W.4
Chan, C.C.5
Caspi, R.R.6
-
22
-
-
20444476217
-
Induction of tolerance to factor VIII inhibitors by gene therapy with immunodominant A2 and C2 domains presented by B cells as Ig fusion proteins
-
Lei T.C., and Scott D.W. Induction of tolerance to factor VIII inhibitors by gene therapy with immunodominant A2 and C2 domains presented by B cells as Ig fusion proteins. Blood 105 (2005) 4865-4870
-
(2005)
Blood
, vol.105
, pp. 4865-4870
-
-
Lei, T.C.1
Scott, D.W.2
-
23
-
-
11144357191
-
Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells
-
Bensinger S.J., Walsh P.T., Zhang J., Carroll M., Parsons R., Rathmell J.C., Thompson C.B., Burchill M.A., Farrar M.A., and Turka L.A. Distinct IL-2 receptor signaling pattern in CD4+CD25+ regulatory T cells. J. Immunol. 172 (2004) 5287-5296
-
(2004)
J. Immunol.
, vol.172
, pp. 5287-5296
-
-
Bensinger, S.J.1
Walsh, P.T.2
Zhang, J.3
Carroll, M.4
Parsons, R.5
Rathmell, J.C.6
Thompson, C.B.7
Burchill, M.A.8
Farrar, M.A.9
Turka, L.A.10
-
24
-
-
18244400088
-
Single cell analysis shows decreasing Foxp3 and TGF-β1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes
-
Pop S.M., Wong C.P., Culton D.A., Clarke S.H., and Tisch R. Single cell analysis shows decreasing Foxp3 and TGF-β1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes. J. Exp. Med. 201 (2005) 1333-1346
-
(2005)
J. Exp. Med.
, vol.201
, pp. 1333-1346
-
-
Pop, S.M.1
Wong, C.P.2
Culton, D.A.3
Clarke, S.H.4
Tisch, R.5
-
25
-
-
6344231287
-
Murine CD4+CD25+ regulatory T cells fail to undergo chromatin remodeling across the proximal promoter region of the IL-2 gene
-
Su L., Creusot R.J., Gallo E.M., Chan S.M., Utz P.J., Fathman C.G., and Ermann J. Murine CD4+CD25+ regulatory T cells fail to undergo chromatin remodeling across the proximal promoter region of the IL-2 gene. J. Immunol. 173 (2004) 4994-5001
-
(2004)
J. Immunol.
, vol.173
, pp. 4994-5001
-
-
Su, L.1
Creusot, R.J.2
Gallo, E.M.3
Chan, S.M.4
Utz, P.J.5
Fathman, C.G.6
Ermann, J.7
-
27
-
-
0141920662
-
Cutting edge: CD28 controls peripheral homeostasis of CD4+CD25+ regulatory T cells
-
Tang Q., Henriksen K.J., Boden E.K., Tooley A.J., Ye J., Subudhi S.K., Zheng X.X., Strom T.B., and Bluestone J.A. Cutting edge: CD28 controls peripheral homeostasis of CD4+CD25+ regulatory T cells. J. Immunol. 171 (2003) 3348-3352
-
(2003)
J. Immunol.
, vol.171
, pp. 3348-3352
-
-
Tang, Q.1
Henriksen, K.J.2
Boden, E.K.3
Tooley, A.J.4
Ye, J.5
Subudhi, S.K.6
Zheng, X.X.7
Strom, T.B.8
Bluestone, J.A.9
-
28
-
-
10844252294
-
Control of Foxp3+CD4+CD25+ regulatory T cells activation and function by dendritic cells
-
Fehervari Z., and Sakaguchi S. Control of Foxp3+CD4+CD25+ regulatory T cells activation and function by dendritic cells. Int. Immunol. 16 (2004) 1769-1780
-
(2004)
Int. Immunol.
, vol.16
, pp. 1769-1780
-
-
Fehervari, Z.1
Sakaguchi, S.2
-
29
-
-
0036773319
-
Inhibition of human T cell proliferation by CTLA-4 utilizeds CD80 and requires CD25+ regulatory T cells
-
Manzotti C.N., Tipping H., Perry L.C., Mead K.I., Blair P.J., Zheng Y., and Sansom D.M. Inhibition of human T cell proliferation by CTLA-4 utilizeds CD80 and requires CD25+ regulatory T cells. Eur. J. Immunol. 32 (2002) 2888-2896
-
(2002)
Eur. J. Immunol.
, vol.32
, pp. 2888-2896
-
-
Manzotti, C.N.1
Tipping, H.2
Perry, L.C.3
Mead, K.I.4
Blair, P.J.5
Zheng, Y.6
Sansom, D.M.7
-
30
-
-
0042512461
-
Direct expansion of functional CD4+CD25+ regulatory T cells by antigen-processing dendritic cells
-
Yamazaki S., Iyoda T., Tarbell K., Olson K., Velinzon K., Inaba K., and Steinman R.M. Direct expansion of functional CD4+CD25+ regulatory T cells by antigen-processing dendritic cells. J. Exp. Med. 198 (2003) 235-247
-
(2003)
J. Exp. Med.
, vol.198
, pp. 235-247
-
-
Yamazaki, S.1
Iyoda, T.2
Tarbell, K.3
Olson, K.4
Velinzon, K.5
Inaba, K.6
Steinman, R.M.7
-
31
-
-
1342345915
-
CD86 and CD80 differentially modulate the suppressive function of human regulatory T cells
-
Zheng Y., Manzotti C.N., Liu M., Burke F., Mead K.I., and Sansom D.M. CD86 and CD80 differentially modulate the suppressive function of human regulatory T cells. J. Immunol. 172 (2004) 2778-2784
-
(2004)
J. Immunol.
, vol.172
, pp. 2778-2784
-
-
Zheng, Y.1
Manzotti, C.N.2
Liu, M.3
Burke, F.4
Mead, K.I.5
Sansom, D.M.6
-
32
-
-
0030840464
-
STATs and gene regulation
-
Darnell J.E. STATs and gene regulation. Science 277 (1997) 1630-1635
-
(1997)
Science
, vol.277
, pp. 1630-1635
-
-
Darnell, J.E.1
-
34
-
-
0033034365
-
Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils
-
Takeda K., Clausen B.E., Kaisho T., Tsujimura T., Terada N., Forster I., and Akira S. Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils. Immunity 10 (1999) 39-49
-
(1999)
Immunity
, vol.10
, pp. 39-49
-
-
Takeda, K.1
Clausen, B.E.2
Kaisho, T.3
Tsujimura, T.4
Terada, N.5
Forster, I.6
Akira, S.7
-
35
-
-
0037452789
-
STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity
-
Welte T., Zhang S.S., Wang T., Zhang Z., Hesslein D.G., Yin Z., Kano A., Iwamoto Y., Li E., Craft J.E., Bothwell A.L., Fikrig E., Koni P.A., Flavell R.A., and Fu X.Y. STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity. Proc. Natl. Acad. Sci. USA 100 (2003) 1879-1884
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 1879-1884
-
-
Welte, T.1
Zhang, S.S.2
Wang, T.3
Zhang, Z.4
Hesslein, D.G.5
Yin, Z.6
Kano, A.7
Iwamoto, Y.8
Li, E.9
Craft, J.E.10
Bothwell, A.L.11
Fikrig, E.12
Koni, P.A.13
Flavell, R.A.14
Fu, X.Y.15
-
36
-
-
0141790820
-
A critical role for STAT3 signaling in immune tolerance
-
Cheng F., Wang H.W., Cuenca A., Huang M., Ghansah T., Brayer J., Kerr W.G., Takeda K., Akira S., Schoenberger S.P., Yu H., Jove R., and Sotomayor E.M. A critical role for STAT3 signaling in immune tolerance. Immunity 19 (2003) 425-436
-
(2003)
Immunity
, vol.19
, pp. 425-436
-
-
Cheng, F.1
Wang, H.W.2
Cuenca, A.3
Huang, M.4
Ghansah, T.5
Brayer, J.6
Kerr, W.G.7
Takeda, K.8
Akira, S.9
Schoenberger, S.P.10
Yu, H.11
Jove, R.12
Sotomayor, E.M.13
-
37
-
-
4644249098
-
IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation
-
Park S.J., Nakagawa T., Kitamura H., Atsumi T., Kamon H., Sawa S., Kamimura D., Ueda N., Iwakura Y., Ishihara K., Murakami M., and Hirano T. IL-6 regulates in vivo dendritic cell differentiation through STAT3 activation. J. Immunol. 173 (2004) 3844-3854
-
(2004)
J. Immunol.
, vol.173
, pp. 3844-3854
-
-
Park, S.J.1
Nakagawa, T.2
Kitamura, H.3
Atsumi, T.4
Kamon, H.5
Sawa, S.6
Kamimura, D.7
Ueda, N.8
Iwakura, Y.9
Ishihara, K.10
Murakami, M.11
Hirano, T.12
-
38
-
-
10744232925
-
Essential role of STAT3 in body weight and glucose homeostasis
-
Cui Y., Huang L., Elefteriou F., Yang G., Shelton J.M., Giles J.E., Oz O.K., Pourbahrami T., Lu C.Y., Richardson J.A., Karsenty G., and Li C. Essential role of STAT3 in body weight and glucose homeostasis. Mol. Cell. Biol. 24 (2004) 258-269
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 258-269
-
-
Cui, Y.1
Huang, L.2
Elefteriou, F.3
Yang, G.4
Shelton, J.M.5
Giles, J.E.6
Oz, O.K.7
Pourbahrami, T.8
Lu, C.Y.9
Richardson, J.A.10
Karsenty, G.11
Li, C.12
-
39
-
-
33947162110
-
Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation
-
Laurence A., Tato C.M., Davidson T.S., Kanno Y., Chen Z., Yao Z., Blank R.B., Meylan F., Siegel R., Hennighausen L., Shevach E.M., and O'shea J.J. Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation. Immunity 26 (2007) 371-381
-
(2007)
Immunity
, vol.26
, pp. 371-381
-
-
Laurence, A.1
Tato, C.M.2
Davidson, T.S.3
Kanno, Y.4
Chen, Z.5
Yao, Z.6
Blank, R.B.7
Meylan, F.8
Siegel, R.9
Hennighausen, L.10
Shevach, E.M.11
O'shea, J.J.12
-
40
-
-
0034254225
-
Role of STAT3 in lipopolysaccharide-induced IL-10 gene expression
-
Benkhart E.M., Siedlar M., Wedel A., Werner T., and Ziegler-Heitbrock H.W. Role of STAT3 in lipopolysaccharide-induced IL-10 gene expression. J. Immunol. 165 (2000) 1612-1617
-
(2000)
J. Immunol.
, vol.165
, pp. 1612-1617
-
-
Benkhart, E.M.1
Siedlar, M.2
Wedel, A.3
Werner, T.4
Ziegler-Heitbrock, H.W.5
|