Abnormal stat activation, hematopoietic homeostasis, and innate immunity in c-fes(-/-) mice

Immunity

Volumn 13, Issue 3, 2000, Pages 397-407

  Hackenmiller, Renee ^a   Kim, Jynho ^b   Feldman, Ricardo A ^b   Simon, M Celeste ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 6; STAT PROTEIN;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; EMBRYO DEVELOPMENT; GENE LOCUS; HEMATOPOIESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTO ONCOGENE; SIGNAL TRANSDUCTION;

EID: 0033672653     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(00)00039-X     Document Type: Article

References (59)

1. Rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cells
2. Cytokines: Coordinators of immune and inflammatory responses
3. Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell lines
4. Granulocyte-macrophage colony-stimulating factor stimulates JAK2 signaling pathway and rapidly activates p93fes, Stat1 p91, and Stat3 p92 in polymorphonuclear leukocytes
5. Genetic control of experimental lyme arthritis in the absence of specific immunity
6. Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity
7. Rapid simultaneous measurement of DNA, protein, and cell volume in single cells from large mammalian cell populations
8. Stats and gene regulation
9. Jak-Stat pathways and transcriptional activation in response to IFHs and other extracellular signaling proteins
10. In vivo administration of recombinant granulocyte-macrophage colony-stimulating factor results in a reversible inhibition of primary B lymphopoiesis
11. Specific expression of the human cellular fps/fes-encoded protein NCP92 in normal and leukemic myeloid cells
12. Selective potentiation of c-fps/fes transforming activity by a phosphatase inhibitor
13. Stat5A-deficient mice demonstrate a defect in granulocyte-macrophage colony-stimulating factor-induced proliferation and gene expression
14. Antisense strategies to characterize the role of genes and oncogenes involved in myeloid differentiation
15. Susceptibility to infection and altered hematopoiesis in mice deficient in both P- and E-selectins
16. PU.1 and Spi-B are required for normal B cell receptor-mediated signal transduction
17. Appearance of membrane-bound tyrosine kinase during differentiation of HL-60 leukemia cells by immune interferon and tumor necrosis factor
18. The Fps/Fes protein-tyrosine kinase promotes angiogenesis in transgenic mice
19. c-fps/fes protein-tyrosine kinase is implicated in a signaling pathway triggered by granulocyte-macrophage colony-stimulating factor and interleukin-3
20. Erythropoietin induces tyrosine phosphorylation and kinase activity of the c-fps/fes proto-oncogene product in human erythropoietin-responsive cells
21. Signaling through the hematopoietic cytokine receptors
22. The GATA-4 transcription factor transactivates the cardiac muscle-specific troponin C promoter-enhancer in nonmuscle cells
23. Interaction of the c-fes proto-oncogene product with the interleukin-4 receptor
24. The Fes protein-tyrosine kinase phosphorylates a subset of macrophage proteins that are involved in cell adhesion and cell-cell signaling
25. Hematopoietic commitment during embryonic stem cell differentiation in culture
26. The Syk protein tyrosine kinase is essential for Fcgamma receptor signaling in macrophages and neutrophils
27. Antiapoptotic activity of Stat5 required during terminal stages of myeloid differentiation
28. The cytoplasmic tyrosine kinase FER is associated with the catenin-like substrate pp120 and is activated by growth factors
29. In vivo and in vitro suppression of primary B lymphocytopoiesis by tumor-derived and recombinant granulocyte colony-stimulating factor
30. Co-expression with BCR induces activation of the FES tyrosine kinase and phosphorylation of specific N-terminal BCR tyrosine residues
31. Proto-oncogene expression and dissection of the myeloid growth to differentiation developmental cascade
32. Phosphorylation of a Fes-related protein in response to granulocyte-macrophage colony stimulating factor
33. Expression of the mammalian c-fes protein in hematopoietic cells and identification of a fes-related protein
34. Inhibition of c-fes expression by an antisense oligomer causes apoptosis of HL60 cells induced to granulocytic differentiation
35. Antisense inhibition of c-fes proto-ioncogene blocks PMA-induced macrophage differentiation in HL60 and in FDC-P1/MAC-11 cells
36. Activation of Fes tyrosine kinase by gp130, an interleukin-6 family cytokine signal transducer, and their association
37. Transcriptional regulation of the cyclin D1 promoter by STAT5: Its involvement in cytokine-dependent growth of hematopoietic cells
38. Analysis of hematopoiesis in max 41 transgenic mice that exhibit sustained elevations of blood granulocytes and monocytes
39. Production of homozygous mutant ES cells with a single targeting construct
40. Activation of Stat3 by the c-fes protein-tyrosine kinase
41. PU.1 is not essential for early myeloid gene expression but is required for terminal myeloid differentiation
42. Leukocyte adhesion to endothelium in inflammation
43. Interleukin-3, erythropoietin, and prolactin activate a Stat5-like factor in lymphoid cells
44. c-fes tyrosine kinase binds to and activates Stat3 after granulocyte-macrophage colony-stimulating factor stimulation
45. Contribution of both Stat and SRF/TCF to c-fes promoter activation by granulocyte-macrophage colony-stimulating factor
46. Involvement of the tyrosine kinase fer in cell adhesion
47. Overexpression of HOXB3 in hematopoietic cells causes defective lymphoid development and progressive myeloproliferation
48. Targeted disruption of the murine fps/fes proto-oncogene reveals that Fps/Fes kinase activity is dispensable for hematopoiesis
49. Identification of the differentiation-associated p93 tyrosine protein kinase of HL-60 leukemia cells as the product of the human c-fes locus and its expression in myelomonocytic cells
50. Specific motifs recognized by the SH2 domains of Csk, 3BP2, fps/fes, GRB-2, HCP, SHC, Syk, and Vav
51. Monocyte adherence results in selective induction of novel genes sharing homology with mediators of inflammation and tissue repair
52. OBF-1, a novel B cell-specific coactivator that stimulates immunoglobulin promoter activity through association with octamer-binding proteins
53. Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene
54. Increased neutrophil respiratory burst in bcr-null mutants
55. The SIF binding element confers sis/PDGF inducibility onto the c-fes promoter
56. Isolation and structural analysis of murine c-fes cDNA clones
57. Association of p93(c-fes) tyrosine protein kinase with granulocytic/monocytic differentiation and resistance to differentiating agents in HL-60 leukemia cells
58. K562 leukemia cells transfected with the human c-fes gene acquire the ability to undergo myeloid differentiation
59. Integrins as a primary signal transduction molecule regulating monocyte immediate-early gene induction