Ras activity regulates cyclin e degradation by the Fbw7 pathway

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 27, 2005, Pages 9649-9654

  Minella, Alex C ^a,b   Welcker, Markus ^a   Clurman, Bruce E ^a,b  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Cell cycle; Genetic instability; Mitogen activated protein kinase; Ubiquitination

Indexed keywords

CULLIN; CYCLIN E; F BOX PROTEIN; FBW7 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; RAS PROTEIN; SKP1 CULLIN1 FBW7 UBIQUITIN PROTEIN LIGASE; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARCINOGENESIS; CELL CYCLE; ENZYME ACTIVATION; GENE MUTATION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; NONHUMAN; ONCOGENE H RAS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; UBIQUITINATION;

ANIMALS; CELL CYCLE PROTEINS; CYCLIN E; F-BOX PROTEINS; HELA CELLS; HUMANS; IMMUNOBLOTTING; IMMUNOPRECIPITATION; MICE; MICRONUCLEUS TESTS; MICROSCOPY, FLUORESCENCE; NIH 3T3 CELLS; PHOSPHORYLATION; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS P21(RAS); SIGNAL TRANSDUCTION; UBIQUITIN-PROTEIN LIGASES;

EID: 22144457934     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0503677102     Document Type: Article

References (42)

1. Hinds, P. W., Mittnacht, S., Dulic, V., Arnold, A., Reed, S. I. & Weinberg, R. A. (1992) Cell 70, 993-1006.
2. Sheaff, R. J., Groudine, M., Gordon, M., Roberts, J. M. & Clurman, B. E. (1997) Genes Dev. 11, 1464-1478.
3. Zhao, J., Kennedy, B. K., Lawrence, B. D., Barbie, D. A., Matera, A. G., Fletcher, J. A. & Harlow, E. (2000) Genes Dev. 14, 2283-2297.
4. Liu, E., Li, X., Yan, F., Zhao, Q. & Wu, X. (2004) J. Biol. Chem. 279, 17283-17288.
5. Chen, Z., Indjeian, V. B., McManus, M., Wang, L. & Dynlacht, B. D. (2002) Dev. Cell 3, 339-350.
6. Okuda, M., Horn, H. F., Tarapore, P., Tokuyama, Y., Smulian, A. G., Chan, P. K., Knudsen, E. S., Hofmann, I. A., Snyder, J. D., Bove, K. E. & Fukasawa, K. (2000) Cell 103, 127-140.
7. Geng, Y., Yu, Q., Sicinska, E., Das, M., Schneider, J. E., Bhattacharya, S., Rideout, W. M., Bronson, R. T., Gardner, H. & Sicinski, P. (2003) Cell 114, 431-443.
8. Parisi, T., Beck, A. K., Rougier, N., McNeil, T., Lucian, L., Werb, Z. & Amati, B. (2003) EMBO J. 22, 4794-4803.
9. Hwang, H. & Clurman, B. (2004) Oncogene 24, 2776-2786.
10. Ekholm-Reed, S., Mendez, J., Tedesco, D., Zetterberg, A., Stillman, B. & Reed, S. I. (2004) J. Cell Biol. 165, 789-800.
11. Ohtsubo, M. & Roberts, J. M. (1993) Science 259, 1908-1912.
12. Minella, A. C., Swanger, J., Bryant, E., Welcker, M., Hwang, H. & Clurman, B. E. (2002) Curr. Biol. 12, 1817-1827.
13. Spruck, C. H., Won, K. A. & Reed, S. I. (1999) Nature 401, 297-300.
14. Moray, T. & Geisen, C. (2004) Int. J. Biochem. Cell Biol. 36, 1424-1439.
15. Singer, J. D., Gurian-West, M., Clurman, B. & Roberts, J. M. (1999) Genes Dev. 13, 2375-2387.
16. Koepp, D. M., Schaefer, L. K., Ye, X., Keyomarsi, K., Chu, C., Harper, J. W. & Elledge, S. J. (2001) Science 294, 173-177.
17. Strohmaier, H., Spruck, C. H., Kaiser, P., Won, K. A., Sangfelt, O. & Reed, S. I. (2001) Nature 413, 316-322.
18. Welcker, M., Singer, J., Loeb, K. R., Grim, J., Bloecher, A., Gurien-West, M., Clurman, B. E. & Roberts, J. M. (2003) Mol. Cell 12, 381-392.
19. Ye, X., Nalepa, G., Welcker, M., Kessler, B., Spooner, E., Qin, J., Elledge, S. J., Clurman, B. E. & Harper, J. W. (2004) J. Biol. Chem. 279, 50110-50119.
20. Rajagopalan, H., Jallepalli, P. V., Rago, C., Velculescu, V. E., Kinzler, K. W., Vogelstein, B. & Lengauer, C. (2004) Nature 428, 77-81.
21. Hubalek, M. M., Widschwendter, A., Erdel, M., Gschwendtner, A., Fiegl, H. M., Muller, H. M., Goebel, G., Mueller-Holzner, E., Marth, C., Spruck, C. H., et al. (2004) Oncogene 23, 4187-4192.
22. Nateri, A. S., Riera-Sans, L., Da Costa, C. & Behrens, A. (2004) Science 303, 1374-1378.
23. Gupta-Rossi, N., Le Bail, O., Gonen, H., Brou, C., Logeat, F., Six, E., Ciechanover, A. & Israel, A. (2001) J. Biol. Chem. 276, 34371-34378.
24. Welcker, M., Orian, A., Jin, J., Grim, J. A., Harper, J. W., Eisenman, R. N. & Clurman, B. E. (2004) Proc. Natl. Acad. Sci. USA 101, 9085-9090.
25. Yada, M., Hatakeyama, S., Kamura, T., Nishiyama, M., Tsunematsu, R., Imaki, H., Ishida, N., Okumura, F., Nakayama, K. & Nakayama, K. I. (2004) EMBO J. 23, 2116-2125.
26. Prober, D. A. & Edgar, B. A. (2000) Cell 100, 435-446.
27. Ludde, T., Kubicka, S., Plumpe, J., Liedtke, C., Manns, M. P. & Trautwein, C. (2001) Oncogene 20, 5264-5278.
28. Welcker, M., Orian, A., Grim, J. A., Eisenman, R. N. & Clurman, B. E. (2004) Curr. Biol. 14, 1852-1857.
29. Doisneau-Sixou, S. F., Cestac, P., Faye, J. C., Favre, G. & Sutherland, R. L. (2003) Int. J. Cancer 106, 789-798.
30. Shih, T. Y., Weeks, M. O., Gruss, P., Dhar, R., Oroszlan, S. & Scolnick, E. M. (1982) J. Virol. 42, 253-261.
31. Campbell, S. L., Khosravi-Far, R., Rossman, K. L., Clark, G. J. & Der, C. J. (1998) Oncogene 17, 1395-1413.
32. Peyssonnaux, C., Provot, S., Felder-Schmittbuhl, M. P., Calothy, G. & Eychene, A. (2000) Mol. Cell. Biol. 20, 7068-7079.
33. Musti, A. M., Treier, M. & Bohmann, D. (1997) Science 275, 400-402.
34. Sears, R. C. (2004) Cell Cycle 3, 1133-1137.
35. Clurman, B. E., Sheaff, R. J., Thress, K., Groudine, M. & Roberts, J. M. (1996) Genes Dev. 10, 1979-1990.
36. Coleman, M. L., Marshall, C. J. & Olson, M. F. (2003) EMBO J. 22, 2036-2046.
37. Olson, M. F., Paterson, H. F. & Marshall, C. J. (1998) Nature 394, 295-299.
38. Benanti, J. A. & Galloway, D. A. (2004) Mol. Cell. Biol. 24, 2842-2852.
39. Haas, K., Johannes, C., Geisen, C., Schmidt, T., Karsunky, H., Blass-Kampmann, S., Obe. G. & Moroy, T. (1997) Oncogene 15, 2615-2623.
40. Geisen, C. & Moroy, T. (2002) J. Biol. Chem. 277, 39909-39918.
41. Karsunky, H., Geisen, C., Schmidt, T., Haas, K., Zevnik, B., Gau, E. & Moroy, T. (1999) Oncogene 18, 7816-7824.
42. Ma, T., Van Tine, B. A., Wei, Y., Garrett, M. D., Nelson, D., Adams, P. D., Wang, J., Qin, J., Chow, L. T. & Harper, J. W. (2000) Genes Dev. 14, 2298-2313.