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Volumn , Issue , 2005, Pages 237-245

Optimizing polyplexes into synthetic viruses for tumor-targeted gene therapy

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EID: 34547742677     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/4-431-27879-6_19     Document Type: Chapter
Times cited : (1)

References (40)
  • 1
    • 11844290850 scopus 로고    scopus 로고
    • Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer
    • Boeckle S, Von Gersdorff K, Van Der Piepen S, Culmsee C, Wagner E, Ogris M (2004) Purification of polyethylenimine polyplexes highlights the role of free polycations in gene transfer. J Gene Med 6:1102-1111
    • (2004) J Gene Med , vol.6 , pp. 1102-1111
    • Boeckle, S.1    Von Gersdorff, K.2    Van Der Piepen, S.3    Culmsee, C.4    Wagner, E.5    Ogris, M.6
  • 2
    • 7444223447 scopus 로고    scopus 로고
    • Polymer-coated polyethylenimine/DNA complexes designed for triggered activation by intracellular reduction
    • Carlisle RC, Etrych T, Briggs SS, Preece JA, Ulbrich K, Seymour LW (2004) Polymer-coated polyethylenimine/DNA complexes designed for triggered activation by intracellular reduction. J Gene Med 6:337-344
    • (2004) J Gene Med , vol.6 , pp. 337-344
    • Carlisle, R.C.1    Etrych, T.2    Briggs, S.S.3    Preece, J.A.4    Ulbrich, K.5    Seymour, L.W.6
  • 3
    • 0036371914 scopus 로고    scopus 로고
    • Side-effects of a systemic injection of linear polyethylenimine-DNA complexes
    • Chollet P, Favrot MC, Hurbin A, Coll JL (2002) Side-effects of a systemic injection of linear polyethylenimine-DNA complexes. J Gene Med 4:84-91
    • (2002) J Gene Med , vol.4 , pp. 84-91
    • Chollet, P.1    Favrot, M.C.2    Hurbin, A.3    Coll, J.L.4
  • 4
    • 0034635467 scopus 로고    scopus 로고
    • Decreased binding to proteins and cells of polymeric gene delivery vectors surface modified with a multivalent hydrophilic polymer and retargeting through attachment of transferrin
    • Dash PR et al. (2000) Decreased binding to proteins and cells of polymeric gene delivery vectors surface modified with a multivalent hydrophilic polymer and retargeting through attachment of transferrin. J Biol Chem. 275:3793-3802
    • (2000) J Biol Chem , vol.275 , pp. 3793-3802
    • Dash, P.R.1
  • 5
  • 6
    • 0141569730 scopus 로고    scopus 로고
    • A degradable polyethylenimine derivative with low toxicity for highly efficient gene delivery
    • Forrest ML, Koerber JT, Pack DW (2003) A degradable polyethylenimine derivative with low toxicity for highly efficient gene delivery. Bioconjug Chem 14:934-940
    • (2003) Bioconjug Chem , vol.14 , pp. 934-940
    • Forrest, M.L.1    Koerber, J.T.2    Pack, D.W.3
  • 7
    • 0035214028 scopus 로고    scopus 로고
    • Efficient gene transfer using reversibly cross-linked low molecular weight polyethylenimine
    • Gosselin MA, Guo W, Lee RJ (2001) Efficient gene transfer using reversibly cross-linked low molecular weight polyethylenimine. Bioconjug Chem 12:989-994
    • (2001) Bioconjug Chem , vol.12 , pp. 989-994
    • Gosselin, M.A.1    Guo, W.2    Lee, R.J.3
  • 8
    • 0034294817 scopus 로고    scopus 로고
    • Development of biomaterials for gene therapy
    • Han S, Mahato RI, Sung YK, Kim SW (2000) Development of biomaterials for gene therapy. Mol Ther 2:302-317
    • (2000) Mol Ther , vol.2 , pp. 302-317
    • Han, S.1    Mahato, R.I.2    Sung, Y.K.3    Kim, S.W.4
  • 9
    • 0038103733 scopus 로고    scopus 로고
    • Optical imaging of transferrin targeted PEI/DNA complexes in living subjects
    • Hildebrandt IJ, Iyer M, Wagner E, Gambhir SS (2003) Optical imaging of transferrin targeted PEI/DNA complexes in living subjects. Gene Ther 10:758-764
    • (2003) Gene Ther , vol.10 , pp. 758-764
    • Hildebrandt, I.J.1    Iyer, M.2    Wagner, E.3    Gambhir, S.S.4
  • 10
    • 4544313611 scopus 로고    scopus 로고
    • Long circulation of intravenously administered plasmid DNA delivered with dendritic poly (L-lysine) in the blood flow
    • Kawano T, Okuda T, Aoyagi H, Niidome T (2004) Long circulation of intravenously administered plasmid DNA delivered with dendritic poly (L-lysine) in the blood flow. J Control Release 99:329-337
    • (2004) J Control Release , vol.99 , pp. 329-337
    • Kawano, T.1    Okuda, T.2    Aoyagi, H.3    Niidome, T.4
  • 11
    • 0036021898 scopus 로고    scopus 로고
    • Tumor-targeted gene delivery of tumor necrosis factor-alpha induces tumor necrosis and tumor regression without systemic toxicity
    • Kircheis R et al. (2002) Tumor-targeted gene delivery of tumor necrosis factor-alpha induces tumor necrosis and tumor regression without systemic toxicity. Cancer Gene Ther 9:673-680
    • (2002) Cancer Gene Ther , vol.9 , pp. 673-680
    • Kircheis, R.1
  • 12
    • 0035131596 scopus 로고    scopus 로고
    • Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application
    • Kircheis R et al. (2001) Polyethylenimine/DNA complexes shielded by transferrin target gene expression to tumors after systemic application. Gene Ther 8:28-40
    • (2001) Gene Ther , vol.8 , pp. 28-40
    • Kircheis, R.1
  • 13
    • 4544316936 scopus 로고    scopus 로고
    • Dendritic polyamines: Simple access to new materials with defined treelike structures for application in nonviral gene delivery
    • Kramer M et al. (2004) Dendritic polyamines: simple access to new materials with defined treelike structures for application in nonviral gene delivery. Chembiochem 5:1081-1087
    • (2004) Chembiochem , vol.5 , pp. 1081-1087
    • Kramer, M.1
  • 14
    • 0142072936 scopus 로고    scopus 로고
    • Novel shielded transferrin-polyethylene glycol-polyethylenimine/DNA complexes for systemic tumor-targeted gene transfer
    • Kursa M et al. (2003) Novel Shielded Transferrin-Polyethylene Glycol-Polyethylenimine/DNA Complexes for Systemic Tumor-Targeted Gene Transfer. Bioconjug Chem 14:222-231
    • (2003) Bioconjug Chem , vol.14 , pp. 222-231
    • Kursa, M.1
  • 15
    • 0036740007 scopus 로고    scopus 로고
    • Biodegradable, endosome disruptive, and cationic network-type polymer as a highly efficient and nontoxic gene delivery carrier
    • Lim YB, Kim SM, Suh H, Park JS (2002) Biodegradable, endosome disruptive, and cationic network-type polymer as a highly efficient and nontoxic gene delivery carrier. Bioconjug Chem 13:952-957
    • (2002) Bioconjug Chem , vol.13 , pp. 952-957
    • Lim, Y.B.1    Kim, S.M.2    Suh, H.3    Park, J.S.4
  • 16
    • 0034993240 scopus 로고    scopus 로고
    • The enhanced permeability and retention (EPR) effect in tumor vasculature: The key role of tumor-selective macromolecular drug targeting
    • Maeda H (2001) The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv Enzyme Regul 41:189-207
    • (2001) Adv Enzyme Regul , vol.41 , pp. 189-207
    • Maeda, H.1
  • 17
    • 0000956945 scopus 로고    scopus 로고
    • Gene transfer mediated by influenza virus peptides: The role of peptide sequence
    • Mechtler K, Wagner E (1997) Gene transfer mediated by influenza virus peptides: the role of peptide sequence. New J Chem 21:105-11
    • (1997) New J Chem , vol.21 , pp. 105-111
    • Mechtler, K.1    Wagner, E.2
  • 18
    • 0141681120 scopus 로고    scopus 로고
    • Pegylated polyethylenimine-fab' antibody fragment conjugates for targeted gene delivery to human ovarian carcinoma cells
    • Merdan T et al. (2003) Pegylated polyethylenimine-fab' antibody fragment conjugates for targeted gene delivery to human ovarian carcinoma cells. Bioconjug Chem 14:989-996
    • (2003) Bioconjug Chem , vol.14 , pp. 989-996
    • Merdan, T.1
  • 19
    • 1542306939 scopus 로고    scopus 로고
    • Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression
    • Miyata K et al. (2004) Block catiomer polyplexes with regulated densities of charge and disulfide cross-linking directed to enhance gene expression. J Am Chem Soc 126:2355-2361
    • (2004) J Am Chem Soc , vol.126 , pp. 2355-2361
    • Miyata, K.1
  • 20
    • 0032938324 scopus 로고    scopus 로고
    • PEGylated DNA/transferrin-PEI complexes: Reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery
    • Ogris M, Brunner S, Schuller S, Kircheis R, Wagner E (1999) PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery. Gene Ther 6:595-605
    • (1999) Gene Ther , vol.6 , pp. 595-605
    • Ogris, M.1    Brunner, S.2    Schuller, S.3    Kircheis, R.4    Wagner, E.5
  • 21
    • 0141990620 scopus 로고    scopus 로고
    • Tumortargeted gene therapy: Strategies for the preparation of ligand-polyethylene glycolpolyethylenimine/DNA complexes
    • Ogris M, Walker G, Blessing T, Kircheis R, Wolschek M, Wagner E (2003) Tumortargeted gene therapy: strategies for the preparation of ligand-polyethylene glycolpolyethylenimine/DNA complexes. J Control Release 91:173-181
    • (2003) J Control Release , vol.91 , pp. 173-181
    • Ogris, M.1    Walker, G.2    Blessing, T.3    Kircheis, R.4    Wolschek, M.5    Wagner, E.6
  • 22
    • 0142227090 scopus 로고    scopus 로고
    • Characters of dendritic poly (L-lysine) analogues with the terminal lysines replaced with arginines and histidines as gene carriers in vitro
    • Okuda T, Sugiyama A, Niidome T, Aoyagi H (2004) Characters of dendritic poly (L-lysine) analogues with the terminal lysines replaced with arginines and histidines as gene carriers in vitro. Biomaterials 25:537-544
    • (2004) Biomaterials , vol.25 , pp. 537-544
    • Okuda, T.1    Sugiyama, A.2    Niidome, T.3    Aoyagi, H.4
  • 23
    • 0028223310 scopus 로고
    • Gene transfer in vivo: Sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake
    • Perales JC, Ferkol T, Beegen H, Ratnoff OD, Hanson RW (1994) Gene transfer in vivo: sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake. Proc Natl Acad Sci U S A 91:4086-4090
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 4086-4090
    • Perales, J.C.1    Ferkol, T.2    Beegen, H.3    Ratnoff, O.D.4    Hanson, R.W.5
  • 24
    • 0029789793 scopus 로고    scopus 로고
    • Activation of the complement system by synthetic DNA complexes: A potential barrier for intravenous gene delivery
    • Plank C, Mechtler K, Szoka FJ, Wagner E (1996) Activation of the complement system by synthetic DNA complexes: A potential barrier for intravenous gene delivery. Hum Gene Ther 7:1437-1446
    • (1996) Hum Gene Ther , vol.7 , pp. 1437-1446
    • Plank, C.1    Mechtler, K.2    Szoka, F.J.3    Wagner, E.4
  • 25
    • 0037257707 scopus 로고    scopus 로고
    • Endosomolysis by Masking of a Membrane-Active Agent (EMMA) for cytoplasmic release of macromolecules
    • Rozema DB, Ekena K, Lewis DL, Loomis AG, Wolff JA (2003) Endosomolysis by Masking of a Membrane-Active Agent (EMMA) for Cytoplasmic Release of Macromolecules. Bioconjug Chem 14:51-57
    • (2003) Bioconjug Chem , vol.14 , pp. 51-57
    • Rozema, D.B.1    Ekena, K.2    Lewis, D.L.3    Loomis, A.G.4    Wolff, J.A.5
  • 26
    • 0037265560 scopus 로고    scopus 로고
    • Enhanced cytosolic delivery of plasmid DNA by a sulfhydryl-activatable listeriolysin O/protamine conjugate utilizing cellular reducing potential
    • Saito G, Amidon GL, Lee KD (2003) Enhanced cytosolic delivery of plasmid DNA by a sulfhydryl-activatable listeriolysin O/protamine conjugate utilizing cellular reducing potential. Gene Ther 10:72-83
    • (2003) Gene Ther , vol.10 , pp. 72-83
    • Saito, G.1    Amidon, G.L.2    Lee, K.D.3
  • 27
    • 0038686295 scopus 로고    scopus 로고
    • Targeting of synthetic gene delivery systems
    • Schatzlein AG (2003) Targeting of Synthetic Gene Delivery Systems. J Biomed Biotechnol 2003:149-158
    • (2003) J Biomed Biotechnol , vol.2003 , pp. 149-158
    • Schatzlein, A.G.1
  • 30
    • 4043152644 scopus 로고    scopus 로고
    • Steric stabilization of poly (2-(dimethylamino) ethyl methacrylate)-based polyplexes mediates prolonged circulation and tumor targeting in mice
    • Verbaan FJ, Oussoren C, Snel CJ, Crommelin DJ, Hennink WE, Storm G (2004) Steric stabilization of poly (2-(dimethylamino) ethyl methacrylate)-based polyplexes mediates prolonged circulation and tumor targeting in mice. J Gene Med 6:64-75
    • (2004) J Gene Med , vol.6 , pp. 64-75
    • Verbaan, F.J.1    Oussoren, C.2    Snel, C.J.3    Crommelin, D.J.4    Hennink, W.E.5    Storm, G.6
  • 31
    • 0035910871 scopus 로고    scopus 로고
    • The fate of poly (2-dimethyl amino ethyl) methacrylate-based polyplexes after intravenous administration
    • Verbaan FJ et al. (2001) The fate of poly (2-dimethyl amino ethyl) methacrylate-based polyplexes after intravenous administration. Int J Pharm 214:99-101
    • (2001) Int J Pharm , vol.214 , pp. 99-101
    • Verbaan, F.J.1
  • 32
    • 1842634414 scopus 로고    scopus 로고
    • Targeted nucleic acid delivery into tumors: New avenues for cancer therapy
    • Wagner E, Kircheis R, Walker GF (2004) Targeted nucleic acid delivery into tumors: new avenues for cancer therapy. Biomed Pharmacother 58:152-161
    • (2004) Biomed Pharmacother , vol.58 , pp. 152-161
    • Wagner, E.1    Kircheis, R.2    Walker, G.F.3
  • 34
    • 14044252938 scopus 로고    scopus 로고
    • Toward synthetic viruses: Endosomal pH triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo
    • Walker GF et al. (2005) Toward synthetic viruses: Endosomal pH triggered deshielding of targeted polyplexes greatly enhances gene transfer in vitro and in vivo. Mol Ther 11:418-425.
    • (2005) Mol Ther , vol.11 , pp. 418-425
    • Walker, G.F.1
  • 35
    • 0037231625 scopus 로고    scopus 로고
    • Ligand-directed targeting of genes to the site of disease
    • Wickham TJ (2003) Ligand-directed targeting of genes to the site of disease. Nat Med 9:135-139
    • (2003) Nat Med , vol.9 , pp. 135-139
    • Wickham, T.J.1
  • 36
    • 0036829950 scopus 로고    scopus 로고
    • Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice
    • Wolschek MF et al. (2002) Specific systemic nonviral gene delivery to human hepatocellular carcinoma xenografts in SCID mice. Hepatology 36:1106-1114
    • (2002) Hepatology , vol.36 , pp. 1106-1114
    • Wolschek, M.F.1
  • 37
    • 0023811723 scopus 로고
    • Receptor-mediated gene delivery and expression in vivo
    • Wu GY, Wu CH (1988) Receptor-mediated gene delivery and expression in vivo. J Biol Chem 262:14621-14624
    • (1988) J Biol Chem , vol.262 , pp. 14621-14624
    • Wu, G.Y.1    Wu, C.H.2
  • 38
    • 0033582456 scopus 로고    scopus 로고
    • Chain length of the polylysine in receptor-targeted gene transfer complexes affects duration of reporter gene expression both in vitro and in vivo
    • Ziady AG, Ferkol T, Dawson DV, Perlmutter DH, Davis PB (1999) Chain length of the polylysine in receptor-targeted gene transfer complexes affects duration of reporter gene expression both in vitro and in vivo. J Biol Chem 274:4908-4916
    • (1999) J Biol Chem , vol.274 , pp. 4908-4916
    • Ziady, A.G.1    Ferkol, T.2    Dawson, D.V.3    Perlmutter, D.H.4    Davis, P.B.5
  • 39
    • 0035997509 scopus 로고    scopus 로고
    • The lower-generation polypropylenimine dendrimers are effective gene-transfer agents
    • Zinselmeyer BH, Mackay SP, Schatzlein AG, Uchegbu IF (2002) The lower-generation polypropylenimine dendrimers are effective gene-transfer agents. Pharm Res 19:960-967
    • (2002) Pharm Res , vol.19 , pp. 960-967
    • Zinselmeyer, B.H.1    Mackay, S.P.2    Schatzlein, A.G.3    Uchegbu, I.F.4
  • 40
    • 0034152683 scopus 로고    scopus 로고
    • Systemic linear polyethylenimine (L-PEI) - Mediated gene delivery in the mouse
    • Zou SM, Erbacher P, Remy JS, Behr JP (2000) Systemic linear polyethylenimine (L-PEI) - mediated gene delivery in the mouse. J Gene Med 2:128-134
    • (2000) J Gene Med , vol.2 , pp. 128-134
    • Zou, S.M.1    Erbacher, P.2    Remy, J.S.3    Behr, J.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.