Optimal timing and duration of induction therapy for HIV-1 infection

PLoS Computational Biology

Volumn 3, Issue 7, 2007, Pages 1239-1256

  Curlin, Marcel E ^a,b   Iyer, Shyamala ^b   Mittler, John E ^b  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; CELL PROLIFERATION; STOCHASTIC MODELS; STOCHASTIC SYSTEMS; TIMING CIRCUITS; VIRUSES;

CELL POPULATIONS; CONDITION; DRUG-RESISTANT VIRUS; HIV-1 INFECTIONS; INDUCTION PHASIS; INDUCTION THERAPY; OPTIMAL DELAY; OPTIMAL TIMING; STOCHASTIC SIMULATION MODEL; TARGET CELLS;

MAINTENANCE;

ANTIRETROVIRUS AGENT; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

ANTIVIRAL ACTIVITY; ARTICLE; COMPUTER MODEL; COMPUTER SIMULATION; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MAINTENANCE THERAPY; MOLECULAR DYNAMICS; STOCHASTIC MODEL; TARGET CELL; VIRUS INHIBITION; VIRUS RESISTANCE; ANTIVIRAL RESISTANCE; COMPUTER ASSISTED DRUG THERAPY; DECISION SUPPORT SYSTEM; DISEASE COURSE; DRUG ADMINISTRATION; DRUG COMBINATION; DRUG EFFECT; HALF LIFE TIME; HUMAN; METHODOLOGY; MUTATION; PATHOGENICITY; PATIENT CARE PLANNING; STANDARD; STATISTICAL MODEL; STATISTICS; TIME; TREATMENT OUTCOME; VIRUS LOAD; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; COMPUTER SIMULATION; DECISION SUPPORT TECHNIQUES; DISEASE PROGRESSION; DRUG ADMINISTRATION SCHEDULE; DRUG RESISTANCE, VIRAL; DRUG THERAPY, COMBINATION; DRUG THERAPY, COMPUTER-ASSISTED; HALF-LIFE; HIV INFECTIONS; HIV-1; HUMANS; LOGISTIC MODELS; MUTATION; PATIENT CARE PLANNING; TIME FACTORS; TREATMENT OUTCOME; VIRAL LOAD; VIRUS REPLICATION;

EID: 34547567775     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.0030133     Document Type: Article

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