Viral kinetics and mathematical models

American Journal of Medicine

Volumn 107, Issue 6 SUPPL. 2, 1999, Pages 49-52

  Perelson, Alan S ^a  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; INTERFERON; VIRUS RNA;

CONFERENCE PAPER; DOSE RESPONSE; DRUG EFFICACY; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; MATHEMATICAL MODEL; POPULATION DYNAMICS; PRIORITY JOURNAL; THEORY; VIRUS LOAD;

EID: 0033397149     PISSN: 00029343     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0002-9343(99)00382-4     Document Type: Conference Paper

References (6)

1. Ho D.D., Neumann A.U., Perelson A.S., et al. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature. 373:1995;123-126.
2. Perelson A.S., Neumann A.U., Markowitz M., et al. HIV-1 dynamics in vivo virion clearance rate, infected cell lifespan, and viral generation time . Science. 271:1996;1582-1586.
3. Perelson A.S., Essunger P., Cao Y., et al. Decay characteristics of HIV-1-infected compartments during combination therapy. Nature. 387:1997;188-191.
4. Nguyen T.T., Sedghi-Vaziri A., Wilkes L.B., et al. Fluctuations in viral load (HCV RNA) are relatively insignificant in untreated patients with chronic HCV infection. J Virol Hepatitis. 3:1996;75-78.
5. Neumann A.U., Lam N.P., Dahari H., et al. Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy. Science. 282:1998;103-107.
6. Ramratnam B, Bonhoeffer S, Bonley J, et al. Rapid production and clearance of HIV-1 and hepatitis C virus particles in infected individuals as defined by large volume plasma apheresis. Lancet. in press.