Colloidally stable novel copolymeric system for gene delivery in complete growth media

Journal of Controlled Release

Volumn 121, Issue 1-2, 2007, Pages 28-37

  Agarwal, Ankit ^a   Vilensky, Rita ^b   Stockdale, Anne ^a   Talmon, Yeshayahu ^b   Unfer, Robert C ^c   Mallapragada, Surya K ^a  

^a Iowa State University of Science and Technology   (United States)

^b TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^c Iowa Cancer Research Foundation   (United States)

Author keywords

Block copolymers; Colloidal stability; Cytotoxicity; Gene delivery; Transfection

Indexed keywords

COLLOIDAL STABILITY; GENE DELIVERY; TRANSFECTION;

CELLS; CYTOTOXICITY; GENES; GROWTH KINETICS; HYDROGELS; POSITIVE IONS; PROTEINS;

BLOCK COPOLYMERS;

CATION; COPOLYMER; DIETHYLAMINE; ETHYLENE OXIDE; METHACRYLIC ACID DERIVATIVE; PLASMA PROTEIN; PLASMID DNA; POLOXAMER; POLY(2 DIETHYLAMINOETHYLMETHACRYLATE); POLY(ETHYLENEOXIDE); UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; COLLOID; COMPLEX FORMATION; CONCENTRATION (PARAMETERS); CULTURE MEDIUM; CYTOTOXICITY; DRUG FORMULATION; GENE TARGETING; GENE VECTOR; GENETIC TRANSFECTION; HYDROGEL; INFRARED SPECTROSCOPY; MATERIAL COATING; NANOTECHNOLOGY; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; STEREOCHEMISTRY; TEMPERATURE; TRANSGENE;

BUFFERS; CELL LINE, TUMOR; CELL SURVIVAL; COLLOIDS; CULTURE MEDIA; FEMALE; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GREEN FLUORESCENT PROTEINS; HUMANS; HYDROGEN-ION CONCENTRATION; LIGHT; LUCIFERASES; MATERIALS TESTING; METHACRYLATES; MICROSCOPY, ELECTRON, TRANSMISSION; OVARIAN NEOPLASMS; POLOXAMER; POLYMERS; SCATTERING, RADIATION; TEMPERATURE;

EID: 34547184603     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2007.05.008     Document Type: Article

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