Polyion complex micelles from plasmid DNA and poly(ethylene glycol)-poly(L-lysine) block copolymer as serum-tolerable polyplex system: Physicochemical properties of micelles relevant to gene transfection efficiency

Biomaterials

Volumn 24, Issue 24, 2003, Pages 4495-4506

  Itaka, Keiji ^a,b   Yamauchi, Kyosuke ^a   Harada, Atsushi ^a   Nakamura, Kozo ^b   Kawaguchi, Hiroshi ^b   Kataoka, Kazunori ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Gene vector; Luciferase assay; Micelle; Poly(ethylene glycol) poly(L lysine) (PEG PLL) block copolymer; Polyion complex; Static light scattering; Zeta potential

Indexed keywords

BLOCK COPOLYMERS; COMPLEXATION; CONDENSATION; DNA; GENES; MOLECULAR WEIGHT; POLYETHYLENE GLYCOLS; POLYMERIZATION; STOICHIOMETRY;

COMPLEX MICELLES;

MICELLES;

CHLOROQUINE; COPOLYMER; ION; LYSINE; PHOSPHATE; PLASMID DNA; POLY(ETHYLENE GLYCOL) POLY(LYSINE) BLOCK COPOLYMER; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; CULTURE MEDIUM; DNA VECTOR; GENE EXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; LIGHT SCATTERING; MEASUREMENT; MICELLE; MOLECULAR WEIGHT; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; PRODUCTIVITY; SERUM; STOICHIOMETRY; ZETA POTENTIAL;

EID: 0042061163     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0142-9612(03)00347-8     Document Type: Article

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