메뉴 건너뛰기




Volumn 113, Issue 2, 2006, Pages 173-182

Poly(ethylene glycol)/poly(ε-caprolactone) diblock copolymeric nanoparticles for non-viral gene delivery: The role of charge group and molecular weight in particle formation, cytotoxicity and transfection

Author keywords

Complex; Diblock copolymers; DNA delivery; Nanoparticles; Self assembly

Indexed keywords

BLOCK COPOLYMERS; CYTOLOGY; GENES; MOLECULAR WEIGHT; NANOSTRUCTURED MATERIALS; POLYMERIZATION; TOXICITY;

EID: 33745279554     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.03.021     Document Type: Article
Times cited : (41)

References (34)
  • 1
    • 0037122695 scopus 로고    scopus 로고
    • Development of non-viral vectors for systemic gene delivery
    • Liu F., and Huang L. Development of non-viral vectors for systemic gene delivery. Journal of Controlled Release 78 (2002) 259-266
    • (2002) Journal of Controlled Release , vol.78 , pp. 259-266
    • Liu, F.1    Huang, L.2
  • 4
    • 0032990267 scopus 로고    scopus 로고
    • Potential of low molecular mass chitosan as a DNA delivery system: biocompatibility, body distribution and ability to complex and protect DNA
    • Richardson S.C.W., Kolbe H.V.J., and Duncan R. Potential of low molecular mass chitosan as a DNA delivery system: biocompatibility, body distribution and ability to complex and protect DNA. International Journal of Pharmaceutics 178 (1999) 231-243
    • (1999) International Journal of Pharmaceutics , vol.178 , pp. 231-243
    • Richardson, S.C.W.1    Kolbe, H.V.J.2    Duncan, R.3
  • 5
    • 10044287286 scopus 로고    scopus 로고
    • An investigation on the physicochemical properties of chitosan/DNA polyelectrolyte complexes
    • Liu W., Sun S., Cao Z., Zhang X., Yao K., Lu W.W., and Lux K.D.K. An investigation on the physicochemical properties of chitosan/DNA polyelectrolyte complexes. Biomaterials 26 (2005) 2705-2711
    • (2005) Biomaterials , vol.26 , pp. 2705-2711
    • Liu, W.1    Sun, S.2    Cao, Z.3    Zhang, X.4    Yao, K.5    Lu, W.W.6    Lux, K.D.K.7
  • 6
    • 0032828009 scopus 로고    scopus 로고
    • Synthesis of a single-tailed lipid and investigation of its transfection
    • Tang F., and Hughes J.A. Synthesis of a single-tailed lipid and investigation of its transfection. Journal of Controlled Release 62 (1999) 345-358
    • (1999) Journal of Controlled Release , vol.62 , pp. 345-358
    • Tang, F.1    Hughes, J.A.2
  • 7
    • 13844262634 scopus 로고    scopus 로고
    • Long-circulating DNA-complexed biodegradable multiblock copolymers for gene delivery: degradation profiles and evidence of dysonization
    • Bikram M., Lee M., Chang C.-W., Janat-Amsbury M.-M., Kern S.E., and Kim S.W. Long-circulating DNA-complexed biodegradable multiblock copolymers for gene delivery: degradation profiles and evidence of dysonization. Journal of Controlled Release 103 (2005) 221-233
    • (2005) Journal of Controlled Release , vol.103 , pp. 221-233
    • Bikram, M.1    Lee, M.2    Chang, C.-W.3    Janat-Amsbury, M.-M.4    Kern, S.E.5    Kim, S.W.6
  • 8
    • 3242685065 scopus 로고    scopus 로고
    • Poly(diallyldimethylammonium chlorides) and their N-methyl-N-vinylacetamide copolymer-based DNA-polyplexes: role of molecular weight and charge density in complex formation, stability, and in vitro activity
    • Fischer D., Dautzenberg H., Kunath K., and Kissel T. Poly(diallyldimethylammonium chlorides) and their N-methyl-N-vinylacetamide copolymer-based DNA-polyplexes: role of molecular weight and charge density in complex formation, stability, and in vitro activity. International Journal of Pharmaceutics 280 (2004) 253-269
    • (2004) International Journal of Pharmaceutics , vol.280 , pp. 253-269
    • Fischer, D.1    Dautzenberg, H.2    Kunath, K.3    Kissel, T.4
  • 12
    • 0032855232 scopus 로고    scopus 로고
    • Microencapsulation of DNA using poly(dl-lactide-co-glycolide): stability issues and release characteristics
    • Walter E., Moelling K., Pavlovic J., and Merkle H.P. Microencapsulation of DNA using poly(dl-lactide-co-glycolide): stability issues and release characteristics. Journal of Controlled Release 61 (1999) 361-374
    • (1999) Journal of Controlled Release , vol.61 , pp. 361-374
    • Walter, E.1    Moelling, K.2    Pavlovic, J.3    Merkle, H.P.4
  • 13
    • 0346634895 scopus 로고    scopus 로고
    • In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis
    • Fischer D., Li Y., Ahlemeyer B., Krieglstein J., and Kissel T. In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis. Biomaterials 24 (2003) 1121-1131
    • (2003) Biomaterials , vol.24 , pp. 1121-1131
    • Fischer, D.1    Li, Y.2    Ahlemeyer, B.3    Krieglstein, J.4    Kissel, T.5
  • 14
    • 33745256842 scopus 로고    scopus 로고
    • Selective chemical modification on polyethyleneimine and its effects on transfection efficiency and cytotoxicity
    • Gao X., and Liu D. Selective chemical modification on polyethyleneimine and its effects on transfection efficiency and cytotoxicity. Molecular Therapy 11 (2005) S427-S428
    • (2005) Molecular Therapy , vol.11
    • Gao, X.1    Liu, D.2
  • 16
    • 0032473394 scopus 로고    scopus 로고
    • Protective interactive noncondensing (PINC) polymers for enhanced plasmid distribution and expression in rat skeletal muscle
    • Mumper R.J., Wang J., Klakamp S.L., Nitta H., Anwer K., Tagliaferri F., and Rolland A.P. Protective interactive noncondensing (PINC) polymers for enhanced plasmid distribution and expression in rat skeletal muscle. Journal of Controlled Release 52 (1998) 191-203
    • (1998) Journal of Controlled Release , vol.52 , pp. 191-203
    • Mumper, R.J.1    Wang, J.2    Klakamp, S.L.3    Nitta, H.4    Anwer, K.5    Tagliaferri, F.6    Rolland, A.P.7
  • 17
    • 1842789875 scopus 로고    scopus 로고
    • DNA delivery from photocrosslinked PEG hydrogels: encapsulation efficiency, release profiles, and DNA quality
    • Quick D.J., and Anseth K.S. DNA delivery from photocrosslinked PEG hydrogels: encapsulation efficiency, release profiles, and DNA quality. Journal of Controlled Release 96 (2004) 341-351
    • (2004) Journal of Controlled Release , vol.96 , pp. 341-351
    • Quick, D.J.1    Anseth, K.S.2
  • 18
    • 0037462992 scopus 로고    scopus 로고
    • PEGylated nanoparticles for biological and pharmaceutical applications
    • Otsuka H., Nagasaki Y., and Kataoka K. PEGylated nanoparticles for biological and pharmaceutical applications. Advanced Drug Delivery Reviews 55 (2003) 403-419
    • (2003) Advanced Drug Delivery Reviews , vol.55 , pp. 403-419
    • Otsuka, H.1    Nagasaki, Y.2    Kataoka, K.3
  • 19
    • 0034246015 scopus 로고    scopus 로고
    • Synthesis of poly(ethylene glycol)-block-poly(ethylenimine) possessing an acetal group at the PEG end
    • Akiyama Y., Harada A., Nagasaki Y., and Kataoka K. Synthesis of poly(ethylene glycol)-block-poly(ethylenimine) possessing an acetal group at the PEG end. Macromolecules 33 (2000) 5841-5845
    • (2000) Macromolecules , vol.33 , pp. 5841-5845
    • Akiyama, Y.1    Harada, A.2    Nagasaki, Y.3    Kataoka, K.4
  • 20
    • 0029344655 scopus 로고
    • Formation of polyion complex micelles in an aqueous milieu from a pair of oppositely-charged block copolymers with poly(ethylene glycol) segments
    • Harada A., and Kataoka K. Formation of polyion complex micelles in an aqueous milieu from a pair of oppositely-charged block copolymers with poly(ethylene glycol) segments. Macromolecules 28 (1995) 5294-5299
    • (1995) Macromolecules , vol.28 , pp. 5294-5299
    • Harada, A.1    Kataoka, K.2
  • 21
    • 0031239718 scopus 로고    scopus 로고
    • Water-soluble polyion complex associates of DNA and poly(ethylene glycol)-poly(l-lysine) block copolymer
    • Katayose S., and Kataoka K. Water-soluble polyion complex associates of DNA and poly(ethylene glycol)-poly(l-lysine) block copolymer. Bioconjugate Chemistry 8 (1997) 702-707
    • (1997) Bioconjugate Chemistry , vol.8 , pp. 702-707
    • Katayose, S.1    Kataoka, K.2
  • 22
    • 0037148675 scopus 로고    scopus 로고
    • Block copolymer micelles for delivery of gene and related compounds
    • Kakizawa Y., and Kataoka K. Block copolymer micelles for delivery of gene and related compounds. Advanced Drug Delivery Reviews 54 (2002) 203-222
    • (2002) Advanced Drug Delivery Reviews , vol.54 , pp. 203-222
    • Kakizawa, Y.1    Kataoka, K.2
  • 23
    • 0032595862 scopus 로고    scopus 로고
    • Polyion complex micelles with reactive aldehyde groups on their surface from plasmid DNA and end-functionalized charged block copolymers
    • Kataoka K., Harada A., Wakebayashi D., and Nagasaki Y. Polyion complex micelles with reactive aldehyde groups on their surface from plasmid DNA and end-functionalized charged block copolymers. Macromolecules 32 (1999) 6892-6894
    • (1999) Macromolecules , vol.32 , pp. 6892-6894
    • Kataoka, K.1    Harada, A.2    Wakebayashi, D.3    Nagasaki, Y.4
  • 24
    • 0034990388 scopus 로고    scopus 로고
    • Indomethacin-loaded methoxy poly(ethylene glycol)/poly(ε-caprolaetone) amphiphilic block copolymeric nanosphere: pharmacokinetic characteristics of indomethacin in the normal Sprague-Dawley rats
    • Kim S.Y., Lee Y.M., Shin H.J., and Kang J.S. Indomethacin-loaded methoxy poly(ethylene glycol)/poly(ε-caprolaetone) amphiphilic block copolymeric nanosphere: pharmacokinetic characteristics of indomethacin in the normal Sprague-Dawley rats. Biomaterials 22 (2001) 2049-2056
    • (2001) Biomaterials , vol.22 , pp. 2049-2056
    • Kim, S.Y.1    Lee, Y.M.2    Shin, H.J.3    Kang, J.S.4
  • 25
    • 0037210118 scopus 로고    scopus 로고
    • Toxic characteristics of methoxy poly(ethylene glycol)/poly(ε-caprolactone) nanospheres; in vitro and in vivo studies in the normal mice
    • Kim S.Y., Lee Y.M., Baik D.J., and Kang J.S. Toxic characteristics of methoxy poly(ethylene glycol)/poly(ε-caprolactone) nanospheres; in vitro and in vivo studies in the normal mice. Biomaterials 24 (2003) 55-63
    • (2003) Biomaterials , vol.24 , pp. 55-63
    • Kim, S.Y.1    Lee, Y.M.2    Baik, D.J.3    Kang, J.S.4
  • 26
    • 0032559172 scopus 로고    scopus 로고
    • Methoxy poly(ethylene glycol)/ε-caprolactone amphiphilic block copolymeric micelle containing indomethacin: I. preparation and characterization
    • Shin I.G., Kim S.Y., Lee Y.M., Cho C.S., and Sung Y.K. Methoxy poly(ethylene glycol)/ε-caprolactone amphiphilic block copolymeric micelle containing indomethacin: I. preparation and characterization. Journal of Controlled Release 51 (1998) 1-11
    • (1998) Journal of Controlled Release , vol.51 , pp. 1-11
    • Shin, I.G.1    Kim, S.Y.2    Lee, Y.M.3    Cho, C.S.4    Sung, Y.K.5
  • 27
    • 0032559233 scopus 로고    scopus 로고
    • Methoxy poly(ethylene glycol)/ε-caprolactone amphiphilic block copolymeric micelle containing indomethacin: II. Micelle formation and drug release behaviors
    • Kim S.Y., Shin I.G., Lee Y.M., Cho C.S., and Sung Y.K. Methoxy poly(ethylene glycol)/ε-caprolactone amphiphilic block copolymeric micelle containing indomethacin: II. Micelle formation and drug release behaviors. Journal of Controlled Release 51 (1998) 13-22
    • (1998) Journal of Controlled Release , vol.51 , pp. 13-22
    • Kim, S.Y.1    Shin, I.G.2    Lee, Y.M.3    Cho, C.S.4    Sung, Y.K.5
  • 28
    • 0032484234 scopus 로고    scopus 로고
    • Preparation and characrerization of biodegradable nanospheres composed of methoxy poly(ethylene glycol) and dl-lactide block copolymer as novel drug carriers
    • Kim S.Y., Shin I.G., and Lee Y.M. Preparation and characrerization of biodegradable nanospheres composed of methoxy poly(ethylene glycol) and dl-lactide block copolymer as novel drug carriers. Journal of Controlled Release 56 (1998) 197-208
    • (1998) Journal of Controlled Release , vol.56 , pp. 197-208
    • Kim, S.Y.1    Shin, I.G.2    Lee, Y.M.3
  • 29
    • 4444232233 scopus 로고    scopus 로고
    • Methoxy poly(ethylene glycol)/poly(ε-caprolactone) amphiphilic block copolymeric nanospheres for folate-mediated targeting: I. Preparation and characterization
    • Park E.K., Lee S.B., and Lee Y.M. Methoxy poly(ethylene glycol)/poly(ε-caprolactone) amphiphilic block copolymeric nanospheres for folate-mediated targeting: I. Preparation and characterization. Biomaterials 26 (2005) 1053-1061
    • (2005) Biomaterials , vol.26 , pp. 1053-1061
    • Park, E.K.1    Lee, S.B.2    Lee, Y.M.3
  • 30
    • 0026614994 scopus 로고
    • The determination of ε-amino groups in soluble and poorly soluble proteinaceous materials by a spectrophotometric method using trinitrobenzenesulfonic acid
    • Bubnis W.A., and Ofner III C.M. The determination of ε-amino groups in soluble and poorly soluble proteinaceous materials by a spectrophotometric method using trinitrobenzenesulfonic acid. Analytical Biochemistry 207 (1992) 129-133
    • (1992) Analytical Biochemistry , vol.207 , pp. 129-133
    • Bubnis, W.A.1    Ofner III, C.M.2
  • 32
    • 0038205763 scopus 로고    scopus 로고
    • Polycation gene delivery systems: escape from endosomes to cytosol
    • Kim J.D., and Park K.N. Polycation gene delivery systems: escape from endosomes to cytosol. Journal of Pharmacy and Pharmacology 55 (2003) 721-734
    • (2003) Journal of Pharmacy and Pharmacology , vol.55 , pp. 721-734
    • Kim, J.D.1    Park, K.N.2
  • 33
    • 0037345649 scopus 로고    scopus 로고
    • Low-pH-sensitive PEG-stabilized plasmid-lipid nanoparticles: preparation and characterization
    • Choi J.S., MacKay J.A., and Szoka Jr. F.C. Low-pH-sensitive PEG-stabilized plasmid-lipid nanoparticles: preparation and characterization. Bioconjugate Chemistry 14 (2003) 420-429
    • (2003) Bioconjugate Chemistry , vol.14 , pp. 420-429
    • Choi, J.S.1    MacKay, J.A.2    Szoka Jr., F.C.3
  • 34
    • 0033229887 scopus 로고    scopus 로고
    • Polyelectrolyte vectors for gene delivery: influence of cationic polymer on biophysical properties of complexes formed with DNA
    • Wolfert M.A., Dash P.R., Nazarova O., Oupicky D., and Seymour L.W. Polyelectrolyte vectors for gene delivery: influence of cationic polymer on biophysical properties of complexes formed with DNA. Bioconjugate Chemistry 10 (1999) 993-1004
    • (1999) Bioconjugate Chemistry , vol.10 , pp. 993-1004
    • Wolfert, M.A.1    Dash, P.R.2    Nazarova, O.3    Oupicky, D.4    Seymour, L.W.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.