-
2
-
-
0035952364
-
Thyroid cancer
-
GIMM O: Thyroid cancer. Cancer Lett. (2001) 163:143-156.
-
(2001)
Cancer Lett.
, vol.163
, pp. 143-156
-
-
Gimm, O.1
-
3
-
-
0026669716
-
Thyroid cancer after Chernobyl
-
BAVERSTOCK K, EGLOFF B, PINCHERA A, RUCHTI C, WILLIAMS D: Thyroid cancer after Chernobyl. Nature (1992) 359:21-22.
-
(1992)
Nature
, vol.359
, pp. 21-22
-
-
Baverstock, K.1
Egloff, B.2
Pinchera, A.3
Ruchti, C.4
Williams, D.5
-
4
-
-
0028925694
-
Anaplastic carcinoma of the thyroid: A 24-year experience
-
rd, DRISCOLL D, BAKAMJIAN V, HICKS WL JR, SHEDD DP: Anaplastic carcinoma of the thyroid: a 24-year experience. Head Neck (1995) 17:41-47.
-
(1995)
Head Neck
, vol.17
, pp. 41-47
-
-
Tan, R.K.1
Finley III, R.K.2
Driscoll, D.3
Bakamjian, V.4
Hicks Jr., W.L.5
Shedd, D.P.6
-
5
-
-
0030896418
-
Mutations of the RET proto-oncogene in the multiple endocrine neoplasia type 2 syndromes, related sporadic tumors, and hirschprung disease
-
ENG C, MULLIGAN LM: Mutations of the RET proto-oncogene in the multiple endocrine neoplasia type 2 syndromes, related sporadic tumors, and hirschprung disease. Hum. Mutat. (1997) 9:97-109.
-
(1997)
Hum. Mutat.
, vol.9
, pp. 97-109
-
-
Eng, C.1
Mulligan, L.M.2
-
7
-
-
0034917625
-
Gene therapy for thyroid cancer: Where do we stand?
-
DEGROOT LJ, ZHANG R: Gene therapy for thyroid cancer: where do we stand? J. Clin. Endocrinol. Metab. (2001) 86:2923-2928.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 2923-2928
-
-
Degroot, L.J.1
Zhang, R.2
-
8
-
-
0035030198
-
Delivery systems intended for in vivo gene therapy of cancer: Targeting and replication competent viral vectors
-
GALANIS E, VILE R, RUSSELL S: Delivery systems intended for in vivo gene therapy of cancer: targeting and replication competent viral vectors. Crit. Rev. Oncol. Hematol. (2001) 38:177-192.
-
(2001)
Crit. Rev. Oncol. Hematol.
, vol.38
, pp. 177-192
-
-
Galanis, E.1
Vile, R.2
Russell, S.3
-
9
-
-
0031759729
-
Retrovirus-mediated suicide gene/prodrug therapy targeting thyroid carcinoma using a thyroid-specific promoter
-
BRAIDEN V, NAGAYAMA Y, IITAKA M, NAMBA H, NIWA M, YAMASHITA S: Retrovirus-mediated suicide gene/prodrug therapy targeting thyroid carcinoma using a thyroid-specific promoter. Endocrinology (1998) 139:3996-3999. First demonstration of the feasibility of transcriptionally targeted gene therapy for DTCs.
-
(1998)
Endocrinology
, vol.139
, pp. 3996-3999
-
-
Braiden, V.1
Nagayama, Y.2
Iitaka, M.3
Namba, H.4
Niwa, M.5
Yamashita, S.6
-
11
-
-
0035100611
-
Adenoviral-mediated gene therapy for thyroid carcinoma using thymidine kinase controlled by thyroglobulin promoter demonstrates high specificity and low toxicity
-
ZHANG R, STRAUS FH, DEGROOT LJ: Adenoviral-mediated gene therapy for thyroid carcinoma using thymidine kinase controlled by thyroglobulin promoter demonstrates high specificity and low toxicity. Thyroid (2001) 11:115-123.
-
(2001)
Thyroid
, vol.11
, pp. 115-123
-
-
Zhang, R.1
Straus, F.H.2
Degroot, L.J.3
-
12
-
-
0035098329
-
Construction of gene therapy vectors targeting thyroid cells: Enhancement of activity and specificity with histone deacetylase inhibitors and agents modulating the cyclic adenosine 3′,5′-monophosphate pathway and demonstration of activity in follicular and anaplastic thyroid carcinoma cells
-
KITAZONO M, CHUMAN Y, AIKOU T, FOJO T: Construction of gene therapy vectors targeting thyroid cells: enhancement of activity and specificity with histone deacetylase inhibitors and agents modulating the cyclic adenosine 3′,5′-monophosphate pathway and demonstration of activity in follicular and anaplastic thyroid carcinoma cells. J. Clin. Endocrinol. Metab. (2001) 86:834-840.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 834-840
-
-
Kitazono, M.1
Chuman, Y.2
Aikou, T.3
Fojo, T.4
-
13
-
-
0036788677
-
A tandemly repeated thyroglobulin core promoter has potential to enhance efficacy for tissue-specific gene therapy for thyroid carcinomas
-
TAKEDA T, YAMAZAKI M, MINEMURA K et al.: A tandemly repeated thyroglobulin core promoter has potential to enhance efficacy for tissue-specific gene therapy for thyroid carcinomas. Cancer Gene Ther. (2002) 9:864-874.
-
(2002)
Cancer Gene Ther.
, vol.9
, pp. 864-874
-
-
Takeda, T.1
Yamazaki, M.2
Minemura, K.3
-
14
-
-
0036847436
-
Transcriptionally-targeted retroviral vector for combined suicide and immunomodulating gene therapy of thyroid cancer
-
BARZON L, BONAGURO R, CASTAGLIUOLO I et al.: Transcriptionally-targeted retroviral vector for combined suicide and immunomodulating gene therapy of thyroid cancer. J. Clin. Endocrinol. Metab. (2002) 87:5304-5311. In vitro and animal experiments demonstrate the therapeutic efficacy of targeted HSV-TK/IL-2 gene therapy in DTC.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 5304-5311
-
-
Barzon, L.1
Bonaguro, R.2
Castagliuolo, I.3
-
15
-
-
0037140917
-
Adenovirus HSV-TK construct with thyroid-specific promoter: Enhancement of activity and specificity with histone deacetylase inhibitors and agents modulating the cAMP pathway
-
KITAZONO M, CHUMAN Y, AIKOU T, FOJO T: Adenovirus HSV-TK construct with thyroid-specific promoter: enhancement of activity and specificity with histone deacetylase inhibitors and agents modulating the cAMP pathway. Int. J. Cancer (2002) 99:453-459.
-
(2002)
Int. J. Cancer
, vol.99
, pp. 453-459
-
-
Kitazono, M.1
Chuman, Y.2
Aikou, T.3
Fojo, T.4
-
16
-
-
0033168967
-
Enhanced efficacy of transcriptionally targeted suicide gene/prodrug therapy for thyroid carcinoma with the Cre-loxP system
-
NAGAYAMA Y, NISHIHARA E, IITAKA M, NAMBA H, YAMASHITA S, NIWA M: Enhanced efficacy of transcriptionally targeted suicide gene/prodrug therapy for thyroid carcinoma with the Cre-loxP system. Cancer Res. (1999) 59:3049-3052. The Cre-loxP system, under the control of the thyroglobulin promoter, is used to enhance expression of therapeutic genes in thyroid cancer cells.
-
(1999)
Cancer Res.
, vol.59
, pp. 3049-3052
-
-
Nagayama, Y.1
Nishihara, E.2
Iitaka, M.3
Namba, H.4
Yamashita, S.5
Niwa, M.6
-
17
-
-
0035328634
-
Transcriptional activation of the thyroglobulin promoter directing suicide gene expression by thyroid transcription factor-1 in thyroid cancer cells
-
SHIMURA H, SUZUKI H, MIYAZAKI A et al.: Transcriptional activation of the thyroglobulin promoter directing suicide gene expression by thyroid transcription factor-1 in thyroid cancer cells. Cancer Res. (2001) 61:3640-3646. Transcriptional targeting of ATC is achieved by co-expression of thyroid transcription factor-1 with TG promoter-driven therapeutic genes.
-
(2001)
Cancer Res.
, vol.61
, pp. 3640-3646
-
-
Shimura, H.1
Suzuki, H.2
Miyazaki, A.3
-
18
-
-
0034455321
-
Cell-specific induction of sensitivity to ganciclovir in medullary thyroid carcinoma cells by adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase
-
MINEMURA K, TAKEDA T, MINEMURA K et al.: Cell-specific induction of sensitivity to ganciclovir in medullary thyroid carcinoma cells by adenovirus-mediated gene transfer of herpes simplex virus thymidine kinase. Endocrinology (2000) 141:1814-1822.
-
(2000)
Endocrinology
, vol.141
, pp. 1814-1822
-
-
Minemura, K.1
Takeda, T.2
Minemura, K.3
-
19
-
-
0034690996
-
High level, tissue-specific expression of a modified calcitonin/ calcitonin gene-related peptide promoter in a human medullary thyroid carcinoma cell line
-
MESSINA M, YU DM, LEAROYD DL, BOTH GW, MOLLOY PL, ROBINSON BG: High level, tissue-specific expression of a modified calcitonin/calcitonin gene-related peptide promoter in a human medullary thyroid carcinoma cell line. Mol. Cell. Endocrinol. (2000) 164:219-224. Construction and characterisation of a chimeric enhancer/promoter sequence of the calcitonin/calcitonin gene-related peptide, showing high efficacy and tissue-specificity in MTC cells.
-
(2000)
Mol. Cell. Endocrinol.
, vol.164
, pp. 219-224
-
-
Messina, M.1
Yu, D.M.2
Learoyd, D.L.3
Both, G.W.4
Molloy, P.L.5
Robinson, B.G.6
-
20
-
-
85047695680
-
Effective gene therapy for medullary thyroid carcinoma using recombinant adenovirus inducing tumor-specific expression of interleukin-12
-
YAMAZAKI M, ZHANG R, STRAUS FH et al.: Effective gene therapy for medullary thyroid carcinoma using recombinant adenovirus inducing tumor-specific expression of interleukin-12. Gene Ther. (2002) 9:64-74. Animal experiment to demonstrate the therapeutic efficacy of transcriptionally targeted IL-12 gene therapy for MTC.
-
(2002)
Gene Ther.
, vol.9
, pp. 64-74
-
-
Yamazaki, M.1
Zhang, R.2
Straus, F.H.3
-
21
-
-
0346095388
-
Adenovirus-mediated tumor-specific combined gene therapy using herpes simplex virus thymidine/ganciclovir system and murine interleukin-12 induces effective antitumor activity against medullary thyroid carcinoma
-
YAMAZAKI M, STRAUS FH, MESSINA M et al.: Adenovirus-mediated tumor-specific combined gene therapy using herpes simplex virus thymidine/ganciclovir system and murine interleukin-12 induces effective antitumor activity against medullary thyroid carcinoma. Cancer Gene Ther. (2004) 11:8-15.
-
(2004)
Cancer Gene Ther.
, vol.11
, pp. 8-15
-
-
Yamazaki, M.1
Straus, F.H.2
Messina, M.3
-
22
-
-
0027455042
-
High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas
-
FAGIN JA, MATSUO K, KARMAKAR A, CHEN DL, TANG SH, KOEFFLER HP: High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas. J. Clin. Invest. (1993) 91:179-184.
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 179-184
-
-
Fagin, J.A.1
Matsuo, K.2
Karmakar, A.3
Chen, D.L.4
Tang, S.H.5
Koeffler, H.P.6
-
23
-
-
0027215123
-
Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland
-
DONGHI R, LONGONI A, PILOTTI S, MICHIELI F, DELLA PORTA G, PIEROTTI MA: Gene p53 mutations are restricted to poorly differentiated and undifferentiated carcinomas of the thyroid gland. J. Clin. Invest. (1993) 91:1753-1760.
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 1753-1760
-
-
Donghi, R.1
Longoni, A.2
Pilotti, S.3
Michieli, F.4
Della Porta, G.5
Pierotti, M.A.6
-
24
-
-
0031050368
-
p53 re-expression inhibits proliferation and restores differentiation of human thyroid anaplastic carcinoma cells
-
MORETTI F, FARSETTI A, SODDU S et al.: p53 re-expression inhibits proliferation and restores differentiation of human thyroid anaplastic carcinoma cells. Oncogene (1997) 14:729-740. Demonstration that restoration of p53 activity in p53-null ATC cells leads to expression of thyroid differentiation genes, cell response to TSH and inhibition of cell proliferation.
-
(1997)
Oncogene
, vol.14
, pp. 729-740
-
-
Moretti, F.1
Farsetti, A.2
Soddu, S.3
-
25
-
-
0030047639
-
Reexpression of thyroid peroxidase in a derivative of an undifferentiated thyroid carcinoma cell line by introduction of wild-type p53
-
FAGIN JA, TANG SH, ZEKI K, DI LAURO R, FUSCO A, GONSKY R: Reexpression of thyroid peroxidase in a derivative of an undifferentiated thyroid carcinoma cell line by introduction of wild-type p53. Cancer Res. (1996) 56:765-771.
-
(1996)
Cancer Res.
, vol.56
, pp. 765-771
-
-
Fagin, J.A.1
Tang, S.H.2
Zeki, K.3
Di Lauro, R.4
Fusco, A.5
Gonsky, R.6
-
26
-
-
0032579231
-
Induction of expression of MHC-class-II antigen on human thyroid carcinoma by wild-type p53
-
ZEKI K, TANAKA Y, MORIMOTO I et al.: Induction of expression of MHC-class-II antigen on human thyroid carcinoma by wild-type p53. Int. J. Cancer (1998) 75:391-395.
-
(1998)
Int. J. Cancer
, vol.75
, pp. 391-395
-
-
Zeki, K.1
Tanaka, Y.2
Morimoto, I.3
-
27
-
-
0034458237
-
Effects of exogenous p53 transduction in thyroid tumor cells with different p53 status
-
MORETTI F, NANNI S, FARSETTI A et al.: Effects of exogenous p53 transduction in thyroid tumor cells with different p53 status. J. Clin. Endocrinol. Metab. (2000) 85:302-308.
-
(2000)
J. Clin. Endocrinol. Metab.
, vol.85
, pp. 302-308
-
-
Moretti, F.1
Nanni, S.2
Farsetti, A.3
-
28
-
-
0033868115
-
Inhibition of angiogenesis and tumorigenesis, and induction of dormancy by p53 in a p53-null thyroid carcinoma cell line in vivo
-
NAGAYAMA Y, SHIGEMATSU K, NAMBA H, ZEKI K, YAMASHITA S, NIWA M: Inhibition of angiogenesis and tumorigenesis, and induction of dormancy by p53 in a p53-null thyroid carcinoma cell line in vivo. Anticancer Res. (2000) 20:2723-2728.
-
(2000)
Anticancer Res.
, vol.20
, pp. 2723-2728
-
-
Nagayama, Y.1
Shigematsu, K.2
Namba, H.3
Zeki, K.4
Yamashita, S.5
Niwa, M.6
-
29
-
-
15444352635
-
Therapeutic usefulness of wild-type p53 gene introduction in a p53-null anaplastic thyroid carcinoma cell line
-
NARIMATSU M, NAGAYAMA Y, AKINO K et al.: Therapeutic usefulness of wild-type p53 gene introduction in a p53-null anaplastic thyroid carcinoma cell line. J. Clin. Endocrinol. Metab. (1998) 83:3668-3672.
-
(1998)
J. Clin. Endocrinol. Metab.
, vol.83
, pp. 3668-3672
-
-
Narimatsu, M.1
Nagayama, Y.2
Akino, K.3
-
30
-
-
0031786541
-
Effects of p53-expressing adenovirus on the chemosensitivity and differentiation of anaplastic thyroid cancer cells
-
BLAGOSKLONNY MV, GIANNAKAKOU P, WOJTOWICZ M et al.: Effects of p53-expressing adenovirus on the chemosensitivity and differentiation of anaplastic thyroid cancer cells. J. Clin. Enaocrinol. Metab. (1998) 83:2516-2522.
-
(1998)
J. Clin. Enaocrinol. Metab.
, vol.83
, pp. 2516-2522
-
-
Blagosklonny, M.V.1
Giannakakou, P.2
Wojtowicz, M.3
-
31
-
-
0035127250
-
Growth inhibition and chemosensitivity of poorly differentiated human thyroid cancer cell line (NPA) transfected with p53 gene
-
KIM SB, AHN IM, PARK HJ et al.: Growth inhibition and chemosensitivity of poorly differentiated human thyroid cancer cell line (NPA) transfected with p53 gene. Head Neck (2001) 23:223-229.
-
(2001)
Head Neck
, vol.23
, pp. 223-229
-
-
Kim, S.B.1
Ahn, I.M.2
Park, H.J.3
-
32
-
-
0036776260
-
A histone deacetylase inhibitor enhances killing of undifferentiated thyroid carcinoma cells by p53 gene therapy
-
IMANISHI R, OHTSURU A, IWAMATSU M et al.: A histone deacetylase inhibitor enhances killing of undifferentiated thyroid carcinoma cells by p53 gene therapy. J. Clin. Endocrinol. Metab. (2002) 87:4821-4824.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 4821-4824
-
-
Imanishi, R.1
Ohtsuru, A.2
Iwamatsu, M.3
-
33
-
-
0034913856
-
Low concentrations of the histone deacetylase inhibitor, depsipeptide (FR901228), increase expression of the Na(+)/I(-) symporter and iodine accumulation in poorly differentiated thyroid carcinoma cells
-
KITAZONO M, ROBEY R, ZHAN Z et al.: Low concentrations of the histone deacetylase inhibitor, depsipeptide (FR901228), increase expression of the Na(+)/I(-) symporter and iodine accumulation in poorly differentiated thyroid carcinoma cells. J. Clin. Endocrinol. Metab. (2001) 86:3430-3435.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 3430-3435
-
-
Kitazono, M.1
Robey, R.2
Zhan, Z.3
-
34
-
-
0026496885
-
A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia
-
KASTAN MB, ZHAN Q, EL-DEIRY WS et al.: A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia. Cell(1992) 71:587-597.
-
(1992)
Cell
, vol.71
, pp. 587-597
-
-
Kastan, M.B.1
Zhan, Q.2
El-Deiry, W.S.3
-
35
-
-
0035889252
-
Induction of Gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling
-
DE SMAELE E, ZAZZERONI F, PAPA S et al.: Induction of Gadd45beta by NF-kappaB downregulates pro-apoptotic JNK signalling. Nature (2001) 414:308-313.
-
(2001)
Nature
, vol.414
, pp. 308-313
-
-
De Smaele, E.1
Zazzeroni, F.2
Papa, S.3
-
36
-
-
0042387909
-
Gadd45gamma expression is reduced in anaplastic thyroid cancer and its reexpression results in apoptosis
-
CHUNG HK, YI YW, JUNG NC et al.: Gadd45gamma expression is reduced in anaplastic thyroid cancer and its reexpression results in apoptosis. J. Clin. Endocrinol. Metab. (2003) 88:3913-3920. Demonstration that the Gadd45γ tumour suppressor gene has potential use for gene therapy in ATC.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 3913-3920
-
-
Chung, H.K.1
Yi, Y.W.2
Jung, N.C.3
-
37
-
-
0035318262
-
Ectopic expression of MyD118/Gadd45/CR6 (Gadd45β/α/γ) sensitizes neoplastic cells to genotoxic stress induced apoptosis
-
ZHANG W, HUFFMAN B, LIEBERMANN DA: Ectopic expression of MyD118/Gadd45/CR6 (Gadd45β/α/γ) sensitizes neoplastic cells to genotoxic stress induced apoptosis. Int. J. Oncol. (2001) 18:749-757.
-
(2001)
Int. J. Oncol.
, vol.18
, pp. 749-757
-
-
Zhang, W.1
Huffman, B.2
Liebermann, D.A.3
-
38
-
-
0031586365
-
Thyroid cell transformation inhibits the expression of a novel rat protein tyrosine phosphatase
-
ZHANG L, MARTELLI ML, BATTAGLIA C et al.: Thyroid cell transformation inhibits the expression of a novel rat protein tyrosine phosphatase. Exp. Cell Res. (1997) 235:62-70.
-
(1997)
Exp. Cell Res.
, vol.235
, pp. 62-70
-
-
Zhang, L.1
Martelli, M.L.2
Battaglia, C.3
-
39
-
-
0034458955
-
Rat protein tyrosine phosphatase η suppresses the neoplastic phenotype of retrovirally transformed thyroid cells through the stabilization of p27(Kip1)
-
TRAPASSO F, IULIANO R, BOCCIA A et al.: Rat protein tyrosine phosphatase η suppresses the neoplastic phenotype of retrovirally transformed thyroid cells through the stabilization of p27(Kip1). Mol. Cell. Biol. (2000) 20:9236-9246.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 9236-9246
-
-
Trapasso, F.1
Iuliano, R.2
Boccia, A.3
-
40
-
-
0037442696
-
An adenovirus carrying the rat protein tyrosine phosphatase η suppresses the growth of human thyroid carcinoma cell lines in vitro and in vivo
-
IULIANO R, TRAPASSO F, LE PERA I et al.: An adenovirus carrying the rat protein tyrosine phosphatase η suppresses the growth of human thyroid carcinoma cell lines in vitro and in vivo. Cancer Res. (2003) 63:882-886. Demonstration that transduction of the PTPη gene in ATC cells inhibits cell proliferation.
-
(2003)
Cancer Res.
, vol.63
, pp. 882-886
-
-
Iuliano, R.1
Trapasso, F.2
Le Pera, I.3
-
41
-
-
0034714190
-
PAX-8-PPAR1 fusion oncogene in human thyroid carcinoma
-
KROLL TG, SARRAF P, PECCIARlNI L et al.: PAX-8-PPAR1 fusion oncogene in human thyroid carcinoma. Science (2000) 289:1357. Identification of the PAX8-PPAR-1 fusion oncogene as a tumour-specific molecular event in thyroid tumourigenesis.
-
(2000)
Science
, vol.289
, pp. 1357
-
-
Kroll, T.G.1
Sarraf, P.2
Pecciarlni, L.3
-
42
-
-
0035019640
-
Ligands for peroxisome proliferator-activated receptor gamma inhibit growth and induce apoptosis of human papillary thyroid carcinoma cells
-
OHTA K, ENDO T, HARAGUCHI K, HERSHMAN JM, ONAYA T: Ligands for peroxisome proliferator-activated receptor gamma inhibit growth and induce apoptosis of human papillary thyroid carcinoma cells. J. Clin. Endocrinol. Metab. (2001) 86:2170-2177.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 2170-2177
-
-
Ohta, K.1
Endo, T.2
Haraguchi, K.3
Hershman, J.M.4
Onaya, T.5
-
43
-
-
18644367272
-
Inhibitory effects of peroxisome proliferator-activated receptor gamma on thyroid carcinoma cell growth
-
MARTELLI ML, IULIANO R, LE PERA I et al.: Inhibitory effects of peroxisome proliferator-activated receptor gamma on thyroid carcinoma cell growth. J. Clin. Endocrinol. Metab. (2002) 87:4728-4735.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 4728-4735
-
-
Martelli, M.L.1
Iuliano, R.2
Le Pera, I.3
-
44
-
-
0031661833
-
Somatic mutations of the PTEN tumor suppressor gene in sporadic follicular thyroid tumors
-
HALACHMI N, HALACHMI S, EVRON E et al.: Somatic mutations of the PTEN tumor suppressor gene in sporadic follicular thyroid tumors. Genes Chromosomes Cancer (1998) 23:239-243.
-
(1998)
Genes Chromosomes Cancer
, vol.23
, pp. 239-243
-
-
Halachmi, N.1
Halachmi, S.2
Evron, E.3
-
45
-
-
0030730905
-
Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors
-
DAHIA PL, MARSH DJ, ZHENG Z et al.: Somatic deletions and mutations in the Cowden disease gene, PTEN, in sporadic thyroid tumors. Cancer Res. (1997) 57:4710-4713.
-
(1997)
Cancer Res.
, vol.57
, pp. 4710-4713
-
-
Dahia, P.L.1
Marsh, D.J.2
Zheng, Z.3
-
46
-
-
0035253503
-
Transient ectopic expression of PTEN in thyroid cancer cell lines induces cell cycle arrest and cell type-dependent cell death
-
WENG LP, GIMM O, KUM JB et al.: Transient ectopic expression of PTEN in thyroid cancer cell lines induces cell cycle arrest and cell type-dependent cell death. Hum. Mol. Genet. (2001) 10:251-258.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 251-258
-
-
Weng, L.P.1
Gimm, O.2
Kum, J.B.3
-
47
-
-
0031564954
-
p73 is a human p53-related protein that can induce apoptosis
-
JOST CA, MARIN MC, KAELIN WG JR: p73 is a human p53-related protein that can induce apoptosis. Nature (1997) 389:191-194.
-
(1997)
Nature
, vol.389
, pp. 191-194
-
-
Jost, C.A.1
Marin, M.C.2
Kaelin Jr., W.G.3
-
48
-
-
0141508002
-
p73 tumor-suppressor activity is impaired in human thyroid cancer
-
FRASCA F, VELLA V, ALOISI A et al.: p73 tumor-suppressor activity is impaired in human thyroid cancer. Cancer Res. (2003) 63:5829-5837.
-
(2003)
Cancer Res.
, vol.63
, pp. 5829-5837
-
-
Frasca, F.1
Vella, V.2
Aloisi, A.3
-
49
-
-
0035477398
-
Therapeutic efficacy of E2F1 in pancreatic cancer correlates with TP73 induction
-
RODICKER F, STIEWE T, ZIMMERMANN S, PUTZER BM: Therapeutic efficacy of E2F1 in pancreatic cancer correlates with TP73 induction. Cancer Res. (2001) 61:7052-7055.
-
(2001)
Cancer Res.
, vol.61
, pp. 7052-7055
-
-
Rodicker, F.1
Stiewe, T.2
Zimmermann, S.3
Putzer, B.M.4
-
50
-
-
3042841913
-
Up-regulation of transcriptional factor E2F1 in papillary and anaplastic thyroid cancers
-
ONDA M, NAGAI H, YOSHIDA A et al.: Up-regulation of transcriptional factor E2F1 in papillary and anaplastic thyroid cancers. J. Hum. Genet. (2004) 49(6):312-318.
-
(2004)
J. Hum. Genet.
, vol.49
, Issue.6
, pp. 312-318
-
-
Onda, M.1
Nagai, H.2
Yoshida, A.3
-
51
-
-
0031897273
-
Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice
-
YAMASAKI L, BRONSON R, WILLIAMS BO, DYSON NJ, HARLOW E, JACKS T: Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice. Nat. Genet. (1998) 18:360-364.
-
(1998)
Nat. Genet.
, vol.18
, pp. 360-364
-
-
Yamasaki, L.1
Bronson, R.2
Williams, B.O.3
Dyson, N.J.4
Harlow, E.5
Jacks, T.6
-
52
-
-
0033666776
-
Role of the p53-homologue p73 in E2F1-induced apoptosis
-
STIEWE T, PUTZER BM: Role of the p53-homologue p73 in E2F1-induced apoptosis. Nat. Genet. (2001) 26:464-469.
-
(2001)
Nat. Genet.
, vol.26
, pp. 464-469
-
-
Stiewe, T.1
Putzer, B.M.2
-
53
-
-
0842265037
-
Wild-type p53 gene transfer is not detrimental to normal cells in vivo: Implications for tumor gene therapy
-
BOSSI G, MAZZARO G, PORRELLO A, CRESCENZI M, SODDU S, SACCHI A: Wild-type p53 gene transfer is not detrimental to normal cells in vivo: implications for tumor gene therapy. Oncogene (2004) 23:418-425.
-
(2004)
Oncogene
, vol.23
, pp. 418-425
-
-
Bossi, G.1
Mazzaro, G.2
Porrello, A.3
Crescenzi, M.4
Soddu, S.5
Sacchi, A.6
-
54
-
-
1842529509
-
Gene therapy progress and prospects: Cancer gene therapy using rumor suppressor genes
-
MCNEISH IA, BELL SJ, LEMOINE NR: Gene therapy progress and prospects: cancer gene therapy using rumor suppressor genes. Gene Ther. (2004) 11:497-503.
-
(2004)
Gene Ther.
, vol.11
, pp. 497-503
-
-
Mcneish, I.A.1
Bell, S.J.2
Lemoine, N.R.3
-
55
-
-
1442327614
-
Endocrine aspects of cancer gene therapy
-
BARZON L, BOSCARO M, PALU G: Endocrine aspects of cancer gene therapy. Endocr. Rev. (2004) 25:1-44. Updated review on clinical trials of cancer gene therapy and the potential endocrine side-effects of gene therapy.
-
(2004)
Endocr. Rev.
, vol.25
, pp. 1-44
-
-
Barzon, L.1
Boscaro, M.2
Palu, G.3
-
56
-
-
0035868848
-
Adenovirus-mediated wild-type p 53 gene transfer in patients receiving chemotherapy for advanced non-small-cell lung cancer: Results of a multicenter Phase II study
-
SCHULER M, HERRMANN R, DE GREVE JL et al.: Adenovirus-mediated wild-type p 53 gene transfer in patients receiving chemotherapy for advanced non-small-cell lung cancer: results of a multicenter Phase II study. J. Clin. Oncol. (2001) 19:1750-1758.
-
(2001)
J. Clin. Oncol.
, vol.19
, pp. 1750-1758
-
-
Schuler, M.1
Herrmann, R.2
De Greve, J.L.3
-
57
-
-
0033526357
-
Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer
-
SWISHER SG, ROTH JA, NEMUNAITIS J et al.: Adenovirus-mediated p53 gene transfer in advanced non-small-cell lung cancer. J. Natl. Cancer Inst. (1999) 91:763-771.
-
(1999)
J. Natl. Cancer Inst.
, vol.91
, pp. 763-771
-
-
Swisher, S.G.1
Roth, J.A.2
Nemunaitis, J.3
-
58
-
-
0033950285
-
Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer
-
NEMUNAITIS J, SWISHER SG, TIMMONS T et al.: Adenovirus-mediated p53 gene transfer in sequence with cisplatin to tumors of patients with non-small-cell lung cancer. J. Clin. Oncol. (2000) 18:609-622.
-
(2000)
J. Clin. Oncol.
, vol.18
, pp. 609-622
-
-
Nemunaitis, J.1
Swisher, S.G.2
Timmons, T.3
-
59
-
-
12244298187
-
Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy
-
SWISHER SG, ROTH JA, KOMAKI R et al.: Induction of p53-regulated genes and tumor regression in lung cancer patients after intratumoral delivery of adenoviral p53 (INGN 201) and radiation therapy. Clin. Cancer Res. (2003) 9:93-101.
-
(2003)
Clin. Cancer Res.
, vol.9
, pp. 93-101
-
-
Swisher, S.G.1
Roth, J.A.2
Komaki, R.3
-
61
-
-
0024234603
-
Agent-specific ras oncogene activation in rat thyroid tumours
-
LEMOINE NR, MAYALL ES, WILLIAMS ED, THURSTON V, WYNFORD-THOMAS D: Agent-specific ras oncogene activation in rat thyroid tumours. Oncogene (1988) 3:541-544.
-
(1988)
Oncogene
, vol.3
, pp. 541-544
-
-
Lemoine, N.R.1
Mayall, E.S.2
Williams, E.D.3
Thurston, V.4
Wynford-Thomas, D.5
-
63
-
-
0023870902
-
Structure and expression of c-myc and c-fos proto-oncogenes in thyroid carcinomas
-
TERRIER P, SHENG ZM, SCHLUMBERG ER M et al.: Structure and expression of c-myc and c-fos proto-oncogenes in thyroid carcinomas. Br. J. Cancer (1988) 57:43-47.
-
(1988)
Br. J. Cancer
, vol.57
, pp. 43-47
-
-
Terrier, P.1
Sheng, Z.M.2
Schlumberg, E.R.M.3
-
64
-
-
0029097594
-
Pattern of ras and gsp oncogene mutations in radiation-associated human thyroid tumors
-
CHALLETON C, BOUNACER A, DU VILLARD JA et al.: Pattern of ras and gsp oncogene mutations in radiation-associated human thyroid tumors. Oncogene (1995) 11:601-603.
-
(1995)
Oncogene
, vol.11
, pp. 601-603
-
-
Challeton, C.1
Bounacer, A.2
Du Villard, J.A.3
-
65
-
-
0028808086
-
Activating mutations of the TSH receptor in differentiated thyroid carcinomas
-
RUSSO D, ARTURI F, SCHLUMBERGER M et al.: Activating mutations of the TSH receptor in differentiated thyroid carcinomas. Oncogene (1995) 11:1907-1911.
-
(1995)
Oncogene
, vol.11
, pp. 1907-1911
-
-
Russo, D.1
Arturi, F.2
Schlumberger, M.3
-
66
-
-
0022410391
-
Changes in nuclear proteins on transformation of rat epithelial thyroid cells by a murine sarcoma retrovirus
-
GIANCOTTI V, BERLINGIERI MT, DIFIORE PP, FUSCO A, VECCHIO G, CRANE-ROBINSON C: Changes in nuclear proteins on transformation of rat epithelial thyroid cells by a murine sarcoma retrovirus. Cancer Res. (1985) 45:6051-6057.
-
(1985)
Cancer Res.
, vol.45
, pp. 6051-6057
-
-
Giancotti, V.1
Berlingieri, M.T.2
Difiore, P.P.3
Fusco, A.4
Vecchio, G.5
Crane-Robinson, C.6
-
67
-
-
0023377879
-
Elevated levels of a specific class of nuclear phosphoproteins in cells transformed with v-ras and v-mos oncogenes and by cotransfection with c-myc and polyoma middle T genes
-
GIANCOTTI V, PANI B, D'ANDREA P et al.: Elevated levels of a specific class of nuclear phosphoproteins in cells transformed with v-ras and v-mos oncogenes and by cotransfection with c-myc and polyoma middle T genes. EMBO J. (1987) 6:1981-1987.
-
(1987)
EMBO J.
, vol.6
, pp. 1981-1987
-
-
Giancotti, V.1
Pani, B.2
D'Andrea, P.3
-
68
-
-
0028970056
-
The expression of the high mobility group HMGI (Y) proteins correlates with the malignant phenotype of human thyroid neoplasias
-
CHIAPPETTA G, BANDIERA A, BERLINGIERI MT et al.: The expression of the high mobility group HMGI (Y) proteins correlates with the malignant phenotype of human thyroid neoplasias. Oncogene (1995) 10:1307-1314.
-
(1995)
Oncogene
, vol.10
, pp. 1307-1314
-
-
Chiappetta, G.1
Bandiera, A.2
Berlingieri, M.T.3
-
69
-
-
0032530892
-
Detection of high mobility group I HMGI(Y) protein in the diagnosis of thyroid tumors: HMGI(Y) expression represents a potential diagnostic indicator of carcinoma
-
CHIAPPETTA G, TALLINI G, DE BIASIO MC et al.: Detection of high mobility group I HMGI(Y) protein in the diagnosis of thyroid tumors: HMGI(Y) expression represents a potential diagnostic indicator of carcinoma. Cancer Res. (1998) 58:4193-4198.
-
(1998)
Cancer Res.
, vol.58
, pp. 4193-4198
-
-
Chiappetta, G.1
Tallini, G.2
De Biasio, M.C.3
-
70
-
-
0027231568
-
Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A
-
MULLIGAN LM, KWOK JB, HEALEY CS et al.: Germ-line mutations of the RET proto-oncogene in multiple endocrine neoplasia type 2A. Nature (1993) 363:458-460.
-
(1993)
Nature
, vol.363
, pp. 458-460
-
-
Mulligan, L.M.1
Kwok, J.B.2
Healey, C.S.3
-
71
-
-
0042869892
-
Gene therapeutic approaches for medullary thyroid carcinoma treatment
-
DROSTEN M, PUTZER BM: Gene therapeutic approaches for medullary thyroid carcinoma treatment. J. Mol. Med. (2003) 81:411-419.
-
(2003)
J. Mol. Med.
, vol.81
, pp. 411-419
-
-
Drosten, M.1
Putzer, B.M.2
-
72
-
-
0036915701
-
A new therapeutic approach in medullary thyroid cancer treatment: Inhibition of oncogenic RET signaling by adenoviral vector-mediated expression of a dominant-negative RET mutant
-
DROSTEN M, FRILLING A, STIEWE T, PUTZER BM: A new therapeutic approach in medullary thyroid cancer treatment: inhibition of oncogenic RET signaling by adenoviral vector-mediated expression of a dominant-negative RET mutant. Surgery (2002) 132:991-997.
-
(2002)
Surgery
, vol.132
, pp. 991-997
-
-
Drosten, M.1
Frilling, A.2
Stiewe, T.3
Putzer, B.M.4
-
73
-
-
0038235732
-
Antitumor capacity of a dominant-negative RET proto-oncogene mutant in a medullary thyroid carcinoma model
-
DROSTEN M, STIEWE T, PUTZER BM: Antitumor capacity of a dominant-negative RET proto-oncogene mutant in a medullary thyroid carcinoma model. Hum. Gene Ther. (2003) 14:971-982. Demonstration that adenoviral delivery of a dominant-negative RET mutant gene, under the control of a synthetic C cell-selective calcitonin promoter, is effective against RET-oncogene-related MTC.
-
(2003)
Hum. Gene Ther.
, vol.14
, pp. 971-982
-
-
Drosten, M.1
Stiewe, T.2
Putzer, B.M.3
-
74
-
-
0031843172
-
Mutations in the extracellular domain cause RET loss of function by a dominant negative mechanism
-
COSMA MP, CARDONE M, CARLOMAGNO F, COLANTUONI V: Mutations in the extracellular domain cause RET loss of function by a dominant negative mechanism. Mol. Cell. Biol. (1998) 18:3321-3329.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 3321-3329
-
-
Cosma, M.P.1
Cardone, M.2
Carlomagno, F.3
Colantuoni, V.4
-
75
-
-
0033566948
-
Hammerhead ribozyme-mediated inactivation of mutant RET in medullary thyroid carcinoma
-
PARTHASARATHY R, COTE GJ, GAGEL RF: Hammerhead ribozyme-mediated inactivation of mutant RET in medullary thyroid carcinoma. Cancer Res. (1999) 59:3911-3914.
-
(1999)
Cancer Res.
, vol.59
, pp. 3911-3914
-
-
Parthasarathy, R.1
Cote, G.J.2
Gagel, R.F.3
-
76
-
-
17944365466
-
Inhibition of Ret oncogene activity by the protein tyrosine phosphatase SHP1
-
HENNIGE AM, LAMMERS R, HOPPNER W et al.: Inhibition of Ret oncogene activity by the protein tyrosine phosphatase SHP1. Endocrinology (2001) 142:4441-4447.
-
(2001)
Endocrinology
, vol.142
, pp. 4441-4447
-
-
Hennige, A.M.1
Lammers, R.2
Hoppner, W.3
-
77
-
-
0035937777
-
Differential effects of leukocyte common antigen-related protein on biochemical and biological activities of RET-MEN2A and RET-MEN2B mutant proteins
-
QIAO S, IWASHITA T, FURUKAWA T, YAMAMOTO M, SOBUE G, TAKAHASHI M: Differential effects of leukocyte common antigen-related protein on biochemical and biological activities of RET-MEN2A and RET-MEN2B mutant proteins. J. Biol. Chem. (2001) 276:9460-9467.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 9460-9467
-
-
Qiao, S.1
Iwashita, T.2
Furukawa, T.3
Yamamoto, M.4
Sobue, G.5
Takahashi, M.6
-
78
-
-
9044247864
-
Block of c-myc expression by antisense oligonucleotides inhibits proliferation of human thyroid carcinoma cell lines
-
CERUTTI J, TRAPASSO F, BATTAGLIA C et al.: Block of c-myc expression by antisense oligonucleotides inhibits proliferation of human thyroid carcinoma cell lines. Clin. Cancer Res. (1996) 2:119-126.
-
(1996)
Clin. Cancer Res.
, vol.2
, pp. 119-126
-
-
Cerutti, J.1
Trapasso, F.2
Battaglia, C.3
-
79
-
-
0028860339
-
Inhibition of HMGI-C protein synthesis suppresses retrovirally induced neoplastic transformation of rat thyroid cells
-
BERLINGIERI MT, MANFIOLETTI G, SANTORO M et al.: Inhibition of HMGI-C protein synthesis suppresses retrovirally induced neoplastic transformation of rat thyroid cells. Mol. Cell. Biol. (1995) 15:1545-1553.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 1545-1553
-
-
Berlingieri, M.T.1
Manfioletti, G.2
Santoro, M.3
-
80
-
-
0034636039
-
Adenovirus-mediated suppression of HMGI(Y) protein synthesis as potential therapy of human malignant neoplasias
-
SCALA S, PORTELLA G, FEDELE M, CHIAPPETTA G, FUSCO A: Adenovirus-mediated suppression of HMGI(Y) protein synthesis as potential therapy of human malignant neoplasias. Proc. Natl. Acad. Sci. USA (2000) 97:4256-4261. Selective killing of ATC cells by delivery of the HMGI(Y) antisense sequence.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 4256-4261
-
-
Scala, S.1
Portella, G.2
Fedele, M.3
Chiappetta, G.4
Fusco, A.5
-
81
-
-
0032984348
-
Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo
-
SEBOLT-LEOPOLD JS, DUDLEY DT, HERRERA R et al.: Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo. Nat. Med. (1999) 5:810-816.
-
(1999)
Nat. Med.
, vol.5
, pp. 810-816
-
-
Sebolt-Leopold, J.S.1
Dudley, D.T.2
Herrera, R.3
-
82
-
-
0000468252
-
In vivo studies on the mechanism of the bystander effect
-
FREEMAN SM et al.: In vivo studies on the mechanism of the bystander effect. Cancer Gene Ther. (1994) 1:326-332.
-
(1994)
Cancer Gene Ther.
, vol.1
, pp. 326-332
-
-
Freeman, S.M.1
-
83
-
-
0028323573
-
Development of antitumor immunity following thymidine kinase-mediated killing of experimental brain tumors
-
BARBA D, HARDIN J, SADELAIN M, GAGE FH: Development of antitumor immunity following thymidine kinase-mediated killing of experimental brain tumors. Proc. Natl. Acad. Sci. USA (1994) 91:4348-4352.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 4348-4352
-
-
Barba, D.1
Hardin, J.2
Sadelain, M.3
Gage, F.H.4
-
84
-
-
0032552436
-
Ganciclovir chemoablation of herpes rhymidine kinase suicide gene-modified tumors produces tumor necrosis and induces systemic immune responses
-
MULLEN CA et al.: Ganciclovir chemoablation of herpes rhymidine kinase suicide gene-modified tumors produces tumor necrosis and induces systemic immune responses. Hum. Gene Ther. (1998) 9:2019-2030.
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 2019-2030
-
-
Mullen, C.A.1
-
85
-
-
0030729670
-
Retrovirus-mediated herpes simplex virus thymidine kinase gene transduction renders human thyroid carcinoma cell lines sensitive to ganciclovir and radiation in vitro and in vivo
-
NISHIHARA E, NAGAYAMA Y, MAWATARI F et al.: Retrovirus-mediated herpes simplex virus thymidine kinase gene transduction renders human thyroid carcinoma cell lines sensitive to ganciclovir and radiation in vitro and in vivo. Endocrinology (1997) 138:4577-4583. First animal study reporting the efficacy of suicide gene therapy for thyroid cancer.
-
(1997)
Endocrinology
, vol.138
, pp. 4577-4583
-
-
Nishihara, E.1
Nagayama, Y.2
Mawatari, F.3
-
86
-
-
0041883467
-
Tumor-specific gene therapy for undifferentiated thyroid carcinoma utilizing the telomerase reverse transcriptase promoter
-
TAKEDA T, INABA H, YAMAZAKI M et al.: Tumor-specific gene therapy for undifferentiated thyroid carcinoma utilizing the telomerase reverse transcriptase promoter. J. Clin. Endocrinol. Metab. (2003) 88:3531-3538.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 3531-3538
-
-
Takeda, T.1
Inaba, H.2
Yamazaki, M.3
-
87
-
-
0034018399
-
Gene therapy of established medullary thyroid carcinoma with herpes simplex viral thymidine kinase in a rat tumor model: Relationship of bystander effect and antitumor efficacy
-
ZHANG R, DEGROOT LJ: Gene therapy of established medullary thyroid carcinoma with herpes simplex viral thymidine kinase in a rat tumor model: relationship of bystander effect and antitumor efficacy. Thyroid (2000) 10:313-319.
-
(2000)
Thyroid
, vol.10
, pp. 313-319
-
-
Zhang, R.1
Degroot, L.J.2
-
88
-
-
0034907233
-
Tissue-specific gene expression in medullary thyroid carcinoma cells employing calcitonin regulatory elements and AAV vectors
-
JIANG S, ALTMANN A, GRIMM D et al.: Tissue-specific gene expression in medullary thyroid carcinoma cells employing calcitonin regulatory elements and AAV vectors. Cancer Gene Ther. (2001) 8:469-472.
-
(2001)
Cancer Gene Ther.
, vol.8
, pp. 469-472
-
-
Jiang, S.1
Altmann, A.2
Grimm, D.3
-
89
-
-
85047684770
-
The sodium iodide symporter and its potential role in cancer therapy
-
SPITZWEG C, HARRINGTON KJ, PINKE LA, VILE RG, MORRIS JC: The sodium iodide symporter and its potential role in cancer therapy. J. Clin. Endocrinol. Metab. (2001) 86:3327-3335.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 3327-3335
-
-
Spitzweg, C.1
Harrington, K.J.2
Pinke, L.A.3
Vile, R.G.4
Morris, J.C.5
-
90
-
-
0033083046
-
Radioisotope concentrator gene therapy using the sodium/iodide symporter gene
-
MANDELL RB, MANDELL LZ, LINK CJ JR: Radioisotope concentrator gene therapy using the sodium/iodide symporter gene. Cancer Res. (1999) 59:661-668. Demonstration that NIS-based gene therapy may have both diagnostic and therapeutic applications for cancer.
-
(1999)
Cancer Res.
, vol.59
, pp. 661-668
-
-
Mandell, R.B.1
Mandell, L.Z.2
Link Jr., C.J.3
-
91
-
-
0036401152
-
Adenovirus biodistribution and noninvasive imaging of gene expression in vivo by positron emission tomography using human sodium/iodide symporter as reporter gene
-
GROOT-WASSINK T, ABOAGYE EO, GLASER M, LEMOINE NR, VASSAUX G: Adenovirus biodistribution and noninvasive imaging of gene expression in vivo by positron emission tomography using human sodium/iodide symporter as reporter gene. Hum. Gene Ther. (2002) 13:1723-1735. In vivo imaging of ectopic NIS expression in xenograft rumour models by positron emission tomography.
-
(2002)
Hum. Gene Ther.
, vol.13
, pp. 1723-1735
-
-
Groot-Wassink, T.1
Aboagye, E.O.2
Glaser, M.3
Lemoine, N.R.4
Vassaux, G.5
-
92
-
-
0942301282
-
Imaging of metastatic pulmonary tumors following NIS gene transfer using single photon emission computed romography
-
MARSEE DK, SHEN DH, MACDONALD LR et al.: Imaging of metastatic pulmonary tumors following NIS gene transfer using single photon emission computed romography. Cancer Gene Ther. (2004) 11:121-127.
-
(2004)
Cancer Gene Ther.
, vol.11
, pp. 121-127
-
-
Marsee, D.K.1
Shen, D.H.2
Macdonald, L.R.3
-
93
-
-
0035122323
-
Expression of the human sodium/iodide symporter (hNIS) in xenotransplanted human thyroid carcinoma
-
SMIT JW, SCHRODER-VAN DER ELST JP, KARPERIEN M, QUE I, ROMIJN JA, VAN DER HEIDE D: Expression of the human sodium/iodide symporter (hNIS) in xenotransplanted human thyroid carcinoma. Exp. Clin. Endocrinol. Diabetes (2001) 109:52-55.
-
(2001)
Exp. Clin. Endocrinol. Diabetes
, vol.109
, pp. 52-55
-
-
Smit, J.W.1
Schroder-Van Der Elst, J.P.2
Karperien, M.3
Que, I.4
Romijn, J.A.5
Van Der Heide, D.6
-
94
-
-
0034486007
-
Reestablishment of in vitro and in vivo iodide uptake by transfection of the human sodium iodide symporter (hNIS) in a NIS defective human thyroid carcinoma cell line
-
SMIT JW, SCHRODER-VAN DER ELST JP, KARPERIEN M et al.: Reestablishment of in vitro and in vivo iodide uptake by transfection of the human sodium iodide symporter (hNIS) in a NIS defective human thyroid carcinoma cell line. Thyroid (2000) 10:939-943.
-
(2000)
Thyroid
, vol.10
, pp. 939-943
-
-
Smit, J.W.1
Schroder-Van Der Elst, J.P.2
Karperien, M.3
-
95
-
-
0036963506
-
131I therapy in a xenotransplanted human sodium-iodide symporter-transfected human follicular thyroid carcinoma cell line
-
131I therapy in a xenotransplanted human sodium-iodide symporter-transfected human follicular thyroid carcinoma cell line. J. Clin. Endocrinol. Metab. (2002) 87:1247-1253.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 1247-1253
-
-
Smit, J.W.1
Schroder-Van Der Elst, J.P.2
Karperien, M.3
-
96
-
-
17944375922
-
Ectopic expression of the thyroperoxidase gene augments radioiodide uptake and retention mediated by the sodium iodide symporter in non-small cell lung cancer
-
HUANG M, BATRA RK, KOGAI T et al.: Ectopic expression of the thyroperoxidase gene augments radioiodide uptake and retention mediated by the sodium iodide symporter in non-small cell lung cancer. Cancer Gene Ther. (2001) 8:612-618.
-
(2001)
Cancer Gene Ther.
, vol.8
, pp. 612-618
-
-
Huang, M.1
Batra, R.K.2
Kogai, T.3
-
97
-
-
0035122464
-
Gene therapy with sodium/iodide symporter in hepatocarcinoma
-
HABERKORN U: Gene therapy with sodium/iodide symporter in hepatocarcinoma. Exp. Clin. Endocrinol. Diabetes (2001) 109:60-62.
-
(2001)
Exp. Clin. Endocrinol. Diabetes
, vol.109
, pp. 60-62
-
-
Haberkorn, U.1
-
98
-
-
0036148836
-
Transposition of the thyroid iodide uptake and organification system in nonthyroid tumor cells by adenoviral vector-mediated gene transfers
-
BOLAND A, MAGNON C, FILETTI S et al.: Transposition of the thyroid iodide uptake and organification system in nonthyroid tumor cells by adenoviral vector-mediated gene transfers. Thyroid (2002) 12:19-26.
-
(2002)
Thyroid
, vol.12
, pp. 19-26
-
-
Boland, A.1
Magnon, C.2
Filetti, S.3
-
100
-
-
0036726584
-
Transfected mosaic spheroids: A new model for evaluation of tumour cell killing in targeted radiotherapy and experimental gene therapy
-
BOYD M, MAIRS SC, STEVENSON K et al.: Transfected mosaic spheroids: a new model for evaluation of tumour cell killing in targeted radiotherapy and experimental gene therapy. J. Gene Med. (2002) 4:567-576.
-
(2002)
J. Gene Med.
, vol.4
, pp. 567-576
-
-
Boyd, M.1
Mairs, S.C.2
Stevenson, K.3
-
101
-
-
0034280568
-
Gene therapy of rat medullary thyroid cancer by naked nitric oxide synthase II DNA injection
-
SOLER MN, BOBE P, BENIHOUD K, LEMAIRE G, ROOS BA, LAUSSON S: Gene therapy of rat medullary thyroid cancer by naked nitric oxide synthase II DNA injection. J. Gene Med. (2000) 2:344-352.
-
(2000)
J. Gene Med.
, vol.2
, pp. 344-352
-
-
Soler, M.N.1
Bobe, P.2
Benihoud, K.3
Lemaire, G.4
Roos, B.A.5
Lausson, S.6
-
102
-
-
0034694011
-
A Phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme
-
RAINOV NG: A Phase III clinical evaluation of herpes simplex virus type 1 thymidine kinase and ganciclovir gene therapy as an adjuvant to surgical resection and radiation in adults with previously untreated glioblastoma multiforme. Hum. Gene Ther. (2000) 11:2389-2401.
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 2389-2401
-
-
Rainov, N.G.1
-
103
-
-
0029845608
-
Immune response against medullary thyroid carcinoma (MTC) induced by parental and/or interleukin-2-secreting MTC cells in a rat model of human familial medullary thyroid carcinoma
-
LAUSSON S, FOURNES B, BORREL C, MILHAUD G, TREILHOU-LAHILLE F: Immune response against medullary thyroid carcinoma (MTC) induced by parental and/or interleukin-2-secreting MTC cells in a rat model of human familial medullary thyroid carcinoma. Cancer Immunol. Immunother. (1996) 43:116-123.
-
(1996)
Cancer Immunol. Immunother.
, vol.43
, pp. 116-123
-
-
Lausson, S.1
Fournes, B.2
Borrel, C.3
Milhaud, G.4
Treilhou-Lahille, F.5
-
104
-
-
0032442209
-
Genetic immunotherapy for medullary thyroid carcinoma: Destruction of tumors in mice by in vivo delivery of adenoviral vector transducing the murine interleukin-2 gene
-
ZHANG R, BAUNOCH D, DEGROOT LJ: Genetic immunotherapy for medullary thyroid carcinoma: destruction of tumors in mice by in vivo delivery of adenoviral vector transducing the murine interleukin-2 gene. Thyroid (1998) 8:1137-1146.
-
(1998)
Thyroid
, vol.8
, pp. 1137-1146
-
-
Zhang, R.1
Baunoch, D.2
Degroot, L.J.3
-
105
-
-
0033325218
-
Effective genetic therapy of established medullary thyroid carcinoma with murine interleukin-2: Dissemination and cytotoxicity studies in a rat tumor model
-
ZHANG R, STRAUS FH, DEGROOT LJ: Effective genetic therapy of established medullary thyroid carcinoma with murine interleukin-2: dissemination and cytotoxicity studies in a rat tumor model. Endocrinology (1999) 140:2152-2158. Animal study demonstrating that adenoviral vector-mediated delivery of IL-2 can efficiently eradicate xenograft MTC and confer immunity against rechallenge with wild-type tumor cells. No significant toxicity of IL-2 gene therapy to other organs.
-
(1999)
Endocrinology
, vol.140
, pp. 2152-2158
-
-
Zhang, R.1
Straus, F.H.2
Degroot, L.J.3
-
106
-
-
0034046425
-
Genetic immunotherapy of established tumors with adenoviral vectors transducing murine interleukin-12 subunits in a rat medullary thyroid carcinoma model
-
ZHANG R, DEGROOT LJ: Genetic immunotherapy of established tumors with adenoviral vectors transducing murine interleukin-12 subunits in a rat medullary thyroid carcinoma model. Clin. Endocrinol. (Oxf.) (2000) 52:687-694.
-
(2000)
Clin. Endocrinol. (Oxf.)
, vol.52
, pp. 687-694
-
-
Zhang, R.1
Degroot, L.J.2
-
107
-
-
0348147563
-
Gene therapy of anaplastic thyroid carcinoma with a single-chain interleukin-12 fusion protein
-
SHI Y, PARHAR RS, ZOU M et al.: Gene therapy of anaplastic thyroid carcinoma with a single-chain interleukin-12 fusion protein. Hum. Gene Ther. (2003) 14:1741-1751. Demonstration of efficacy of IL-12 gene therapy for ATC in a tumor xenograft model in nude mice. The antitumour activity was mainly mediated by natural killer cells.
-
(2003)
Hum. Gene Ther.
, vol.14
, pp. 1741-1751
-
-
Shi, Y.1
Parhar, R.S.2
Zou, M.3
-
108
-
-
0033065777
-
Treatment of medullary thyroid carcinoma by combined expression of suicide and interleukin-2 genes
-
SOLER MN, MILHAUD G, LEKMINE F, TREILHOU-LAHILLE F, KLATZMANN D, LAUSSON S: Treatment of medullary thyroid carcinoma by combined expression of suicide and interleukin-2 genes. Cancer Immunol. Immunother. (1999) 48:91-99.
-
(1999)
Cancer Immunol. Immunother.
, vol.48
, pp. 91-99
-
-
Soler, M.N.1
Milhaud, G.2
Lekmine, F.3
Treilhou-Lahille, F.4
Klatzmann, D.5
Lausson, S.6
-
109
-
-
0035663842
-
An adenoviral vector expressing functional heterogeneous proteins herpes simplex viral thymidine kinase and human interleukin-2 has enhanced in vivo antitumor activity against medullary thyroid carcinoma
-
ZHANG R, DEGROOT LJ: An adenoviral vector expressing functional heterogeneous proteins herpes simplex viral thymidine kinase and human interleukin-2 has enhanced in vivo antitumor activity against medullary thyroid carcinoma. Endocr. Relat. Cancer (2001) 8:315-325. Development of an adenoviral vector expressing both HSV-TKand hIL-2 for gene therapy of MTC and demonstration of an antitumour effect superior to that of each single therapeutic gene given alone.
-
(2001)
Endocr. Relat. Cancer
, vol.8
, pp. 315-325
-
-
Zhang, R.1
Degroot, L.J.2
-
110
-
-
0037262395
-
Gene therapy of thyroid cancer via retrovirally-driven combined expression of human interleukin-2 and herpes simplex virus thymidine kinase
-
BARZON L, BONAGURO R, CASTAGLIUOLO I et al.: Gene therapy of thyroid cancer via retrovirally-driven combined expression of human interleukin-2 and herpes simplex virus thymidine kinase. Eur. J. Endocrinol. (2003) 148:73-80. Development of a retroviral vector co-expressing HSV- TKand hIL-2 and demonstration of its enhanced efficacy and in vivo bystander effect in DTC and ATC animal models.
-
(2003)
Eur. J. Endocrinol.
, vol.148
, pp. 73-80
-
-
Barzon, L.1
Bonaguro, R.2
Castagliuolo, I.3
-
111
-
-
0033000339
-
Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: A pilot study in humans
-
PALU G, CAVAGGIONI A, CALVI P et al.: Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: a pilot study in humans. Gene Ther. (1999) 6:330-337. First clinical trial of cancer gene therapy based on combined delivery of a suicide and a cytokine gene. Demonstration of safety and efficacy in patients with recurrent glioblastoma multiforme.
-
(1999)
Gene Ther.
, vol.6
, pp. 330-337
-
-
Palu, G.1
Cavaggioni, A.2
Calvi, P.3
-
112
-
-
1442320481
-
Suicide/cytokine gene therapy in end-stage anaplastic thyroid carcinoma
-
BARZON L, TACCALITI A, FRANCHIN E, PACENTI M, BOSCARO M, PALU G: Suicide/cytokine gene therapy in end-stage anaplastic thyroid carcinoma. Mol. Ther. (2002) 5:S386. First clinical study of gene therapy in patients with thyroid cancer based on combined delivery of a suicide and a cytokine gene. Treatment was safe.
-
(2002)
Mol. Ther.
, vol.5
-
-
Barzon, L.1
Taccaliti, A.2
Franchin, E.3
Pacenti, M.4
Boscaro, M.5
Palu, G.6
-
113
-
-
0036959890
-
Stimulation of autologous antitumor T-cell responses against medullary thyroid carcinoma using tumor lysate-pulsed dendritic cells
-
BACHLEITNER-HOFMANN T, STIFT A, FRIEDL J et al.: Stimulation of autologous antitumor T-cell responses against medullary thyroid carcinoma using tumor lysate-pulsed dendritic cells. J. Clin. Endocrinol. Metab. (2002) 87:1098-1104.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 1098-1104
-
-
Bachleitner-Hofmann, T.1
Stift, A.2
Friedl, J.3
-
114
-
-
0038746621
-
Dendritic cell vaccination: New hope for the treatment of metastasized endocrine malignancies
-
SCHOTT M, SEISSLER J: Dendritic cell vaccination: new hope for the treatment of metastasized endocrine malignancies. Trends Endocnnol. Metab. (2003) 14:156-162.
-
(2003)
Trends Endocnnol. Metab.
, vol.14
, pp. 156-162
-
-
Schott, M.1
Seissler, J.2
-
115
-
-
0034750683
-
Immunotherapy for medullary thyroid carcinoma by dendritic cell vaccination
-
SCHOTT M, SEISSLER J, LETTMANN M, FOUXON V, SCHERBAUM WA, FELDKAMP J: Immunotherapy for medullary thyroid carcinoma by dendritic cell vaccination. J. Clin. Endocrinol. Metab. (2001) 86:4965-4969. Clinical trial of DC vaccination therapy in patients with metastasing MTC, showing safety and efficacy of treatment.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 4965-4969
-
-
Schott, M.1
Seissler, J.2
Lettmann, M.3
Fouxon, V.4
Scherbaum, W.A.5
Feldkamp, J.6
-
116
-
-
18744411513
-
Dendritic cell-based vaccination in solid cancer
-
STIFT A, FRIEDL J, DUBSKY P et al.: Dendritic cell-based vaccination in solid cancer. J. Clin. Oncol. (2003) 21:135-142.
-
(2003)
J. Clin. Oncol.
, vol.21
, pp. 135-142
-
-
Stift, A.1
Friedl, J.2
Dubsky, P.3
-
117
-
-
2442474103
-
Dendritic cell vaccination in medullary thyroid carcinoma
-
STIFT A, SACHET M, YAGUBIAN R et al.: Dendritic cell vaccination in medullary thyroid carcinoma. Clin. Cancer Res. (2004) 10:2944-2953. Clinical trial of DC vaccination therapy in patients with metastasing MTC, showing tumour response in four out of ten treated cases.
-
(2004)
Clin. Cancer Res.
, vol.10
, pp. 2944-2953
-
-
Stift, A.1
Sachet, M.2
Yagubian, R.3
-
118
-
-
0037438481
-
A thyroid tumor-specific antigen formed by the fusion of two self proteins
-
POWELL DJ JR, EISENLOHR LC, ROTHSTEIN JL: A thyroid tumor-specific antigen formed by the fusion of two self proteins. J. Immunol. (2003) 170:861-869. Investigation of the immunogenicity of RET/PTC3, a thyroid tumour-specific fusion protein expressed in thyroid carcinoma.
-
(2003)
J. Immunol.
, vol.170
, pp. 861-869
-
-
Powell Jr., D.J.1
Eisenlohr, L.C.2
Rothstein, J.L.3
-
119
-
-
1642363984
-
CD4(+) T-cell recognition of mutated B-RAF in melanoma patients harboring the V599E mutation
-
SHARKEY MS, LIZEE G, GONZALES MI, PATEL S, TOPALIAN SL: CD4(+) T-cell recognition of mutated B-RAF in melanoma patients harboring the V599E mutation. Cancer Res. (2004) 64:1595-1599.
-
(2004)
Cancer Res.
, vol.64
, pp. 1595-1599
-
-
Sharkey, M.S.1
Lizee, G.2
Gonzales, M.I.3
Patel, S.4
Topalian, S.L.5
-
120
-
-
0032708737
-
Antiangiogenic gene therapy
-
LAU K, BICKNELL R: Antiangiogenic gene therapy. Gene Ther. (1999) 6:1793-1795.
-
(1999)
Gene Ther.
, vol.6
, pp. 1793-1795
-
-
Lau, K.1
Bicknell, R.2
-
121
-
-
0036720708
-
Antiangiogenic and antitumor effects of endostatin on follicular thyroid carcinoma
-
YE C, FENG C, WANG S, LIU X, LIN Y, LI M: Antiangiogenic and antitumor effects of endostatin on follicular thyroid carcinoma. Endocrinology (2002) 143:3522-3528.
-
(2002)
Endocrinology
, vol.143
, pp. 3522-3528
-
-
Ye, C.1
Feng, C.2
Wang, S.3
Liu, X.4
Lin, Y.5
Li, M.6
-
122
-
-
0033607047
-
Modulation of in vivo growth of thyroid tumor-derived cell lines by sense and antisense vascular endothelial growth factor gene
-
BELLETTI B, FERRARO P, ARRA C et al.: Modulation of in vivo growth of thyroid tumor-derived cell lines by sense and antisense vascular endothelial growth factor gene. Oncogens (1999) 18:4860-4869.
-
(1999)
Oncogens
, vol.18
, pp. 4860-4869
-
-
Belletti, B.1
Ferraro, P.2
Arra, C.3
-
123
-
-
0036137466
-
VEGF receptor signaling and endothelial function
-
KLICHE S, WALTENBERGER J: VEGF receptor signaling and endothelial function. IUBMB Life (2001) 52:61-66.
-
(2001)
IUBMB Life
, vol.52
, pp. 61-66
-
-
Kliche, S.1
Waltenberger, J.2
-
124
-
-
0029021660
-
Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium
-
FONG GH, ROSSANT J, GERTSENSTEIN M, BREITMAN ML: Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium. Nature (1995) 376:66-70.
-
(1995)
Nature
, vol.376
, pp. 66-70
-
-
Fong, G.H.1
Rossant, J.2
Gertsenstein, M.3
Breitman, M.L.4
-
125
-
-
13144262858
-
Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate
-
GOLDMAN CK, KENDALL RL, CABRERA G et al.: Paracrine expression of a native soluble vascular endothelial growth factor receptor inhibits tumor growth, metastasis, and mortality rate. Proc. Natl. Acad. Sci. USA (1998) 95:8795-8800.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8795-8800
-
-
Goldman, C.K.1
Kendall, R.L.2
Cabrera, G.3
-
126
-
-
0027421333
-
Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor
-
KENDALL RL, THOMAS KA: Inhibition of vascular endothelial cell growth factor activity by an endogenously encoded soluble receptor. Proc. Natl. Acad. Sci. USA (1993) 90:10705-10709.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10705-10709
-
-
Kendall, R.L.1
Thomas, K.A.2
-
127
-
-
0032502843
-
Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor
-
KONG HL, HECHT D, SONG W et al.: Regional suppression of tumor growth by in vivo transfer of a cDNA encoding a secreted form of the extracellular domain of the flt-1 vascular endothelial growth factor receptor. Hum. Gene Ther. (1998) 9:823-833.
-
(1998)
Hum. Gene Ther.
, vol.9
, pp. 823-833
-
-
Kong, H.L.1
Hecht, D.2
Song, W.3
-
128
-
-
0034655246
-
Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ
-
TAKAYAMA K, UENO H, NAKANISHI Y et al.: Suppression of tumor angiogenesis and growth by gene transfer of a soluble form of vascular endothelial growth factor receptor into a remote organ. Cancer Res. (2000) 60:2169-2177.
-
(2000)
Cancer Res.
, vol.60
, pp. 2169-2177
-
-
Takayama, K.1
Ueno, H.2
Nakanishi, Y.3
-
129
-
-
0842334575
-
sFlt-1 gene therapy of follicular thyroid carcinoma
-
YE C, FENG C, WANG S et al.: sFlt-1 gene therapy of follicular thyroid carcinoma. Endocrinology (2004) 145:817-822. Transfer of sFlt-1 gene effectively inhibits the growth of xenografted human FTC thyroid tumours in immunodeficient mice.
-
(2004)
Endocrinology
, vol.145
, pp. 817-822
-
-
Ye, C.1
Feng, C.2
Wang, S.3
-
130
-
-
0036846926
-
Targeting multiple biological pathways as a strategy to improve the treatment of cancer
-
O'REILLY MS: Targeting multiple biological pathways as a strategy to improve the treatment of cancer. Clin. Cancer Res. (2002) 8:3309-3310.
-
(2002)
Clin. Cancer Res.
, vol.8
, pp. 3309-3310
-
-
O'Reilly, M.S.1
-
131
-
-
18244419396
-
Combined effects of angiostatin and ionizing radiation in antitumour therapy
-
MAUCERI HJ, HANNA NN, BECKETT MA et al.: Combined effects of angiostatin and ionizing radiation in antitumour therapy. Nature (1998) 394:287-291.
-
(1998)
Nature
, vol.394
, pp. 287-291
-
-
Mauceri, H.J.1
Hanna, N.N.2
Beckett, M.A.3
-
132
-
-
0037109023
-
Combined therapy of local and metastatic 4T1 breast tumor in mice using SU6668, an inhibitor of angiogenic receptor tyrosine kinases, and the immunostimulator B7.2-IgG fusion protein
-
HUANG X, WONG MK, YI H et al.: Combined therapy of local and metastatic 4T1 breast tumor in mice using SU6668, an inhibitor of angiogenic receptor tyrosine kinases, and the immunostimulator B7.2-IgG fusion protein. Cancer Res. (2002) 62:5727-5735.
-
(2002)
Cancer Res.
, vol.62
, pp. 5727-5735
-
-
Huang, X.1
Wong, M.K.2
Yi, H.3
-
133
-
-
0034655135
-
Synergy between angiostatin and endostatin: Inhibition of ovarian cancer growth
-
YOKOYAMA Y, DHANABAL M, GRIFFIOEN AW, SUKHATME VP, RAMAKRISHNAN S: Synergy between angiostatin and endostatin: inhibition of ovarian cancer growth. Cancer Res. (2000) 60:2190-2196.
-
(2000)
Cancer Res.
, vol.60
, pp. 2190-2196
-
-
Yokoyama, Y.1
Dhanabal, M.2
Griffioen, A.W.3
Sukhatme, V.P.4
Ramakrishnan, S.5
-
134
-
-
0344188096
-
An adenovirus mutant that replicates selectively in p53-deficient human tumor cells
-
BISCHOFF JR, KIRN DH, WILLIAMS A et al.: An adenovirus mutant that replicates selectively in p53-deficient human tumor cells. Science (1996) 274:373-376.
-
(1996)
Science
, vol.274
, pp. 373-376
-
-
Bischoff, J.R.1
Kirn, D.H.2
Williams, A.3
-
135
-
-
0036078735
-
ONYX-015, an E1B gene-defective adenovirus, induces cell death in human anaplastic thyroid carcinoma cell lines
-
PORTELLA G, SCALA S, VITAGLIANO D, VECCHIO G, FUSCO A: ONYX-015, an E1B gene-defective adenovirus, induces cell death in human anaplastic thyroid carcinoma cell lines. J. Clin. Endocrinol. Metab. (2002) 87:2525-2531. Efficacy of the d/1520 oncotytic adenovirus in an ATC animal model.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 2525-2531
-
-
Portella, G.1
Scala, S.2
Vitagliano, D.3
Vecchio, G.4
Fusco, A.5
-
136
-
-
0242320345
-
ONYX-015 enhances radiation-induced death of human anaplastic thyroid carcinoma cells
-
PORTELLA G, PACELLI R, LIBERTINI S et al.: ONYX-015 enhances radiation-induced death of human anaplastic thyroid carcinoma cells. J. Clin. Endocrinol. Metab. (2003) 88:5027-5032.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 5027-5032
-
-
Portella, G.1
Pacelli, R.2
Libertini, S.3
-
137
-
-
0027473687
-
The Adenovirus E1A gene blocks the differentiation of a thyroid epithelial cell line, however the neoplastic phenotype is achieved only after cooperation with other oncogenes
-
BERLINGIERI MT, SANTORO M, BATTAGLIA C, GRIECO M, FUSCO A: The Adenovirus E1A gene blocks the differentiation of a thyroid epithelial cell line, however the neoplastic phenotype is achieved only after cooperation with other oncogenes. Oncogene (1993) 8:249-255.
-
(1993)
Oncogene
, vol.8
, pp. 249-255
-
-
Berlingieri, M.T.1
Santoro, M.2
Battaglia, C.3
Grieco, M.4
Fusco, A.5
-
138
-
-
0034990761
-
Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: Safety, feasibility and biological activity
-
NEMUNAITIS J, CUNNINGHAM C, BUCHANAN A et al.: Intravenous infusion of a replication-selective adenovirus (ONYX-015) in cancer patients: safety, feasibility and biological activity. Gene Ther. (2001) 8:746-759.
-
(2001)
Gene Ther.
, vol.8
, pp. 746-759
-
-
Nemunaitis, J.1
Cunningham, C.2
Buchanan, A.3
-
139
-
-
20244367717
-
Targeting the replication of adenovirus to p53-defective thyroid carcinoma with a p53-regulated Cre/loxP system
-
NAGAYAMA Y, NISHIHARA E, NAMBA H et al.: Targeting the replication of adenovirus to p53-defective thyroid carcinoma with a p53-regulated Cre/loxP system. Cancer Gene Ther. (2001) 8:36-44.
-
(2001)
Cancer Gene Ther.
, vol.8
, pp. 36-44
-
-
Nagayama, Y.1
Nishihara, E.2
Namba, H.3
-
140
-
-
0023930196
-
Virus-induced thyroiditis
-
SRINIVASAPPA J, GARZELLI C, ONODERA T, RAY U, NOTKINS AL: Virus-induced thyroiditis. Endocrinology (1988) 122:563-566.
-
(1988)
Endocrinology
, vol.122
, pp. 563-566
-
-
Srinivasappa, J.1
Garzelli, C.2
Onodera, T.3
Ray, U.4
Notkins, A.L.5
-
141
-
-
0028998986
-
Enhanced expression of MHC class I molecules on cultured human thyroid follicular cells infected with reovirus through induction of type 1 interferons
-
ATTA MS, IRVING WL, POWELL RJ, TODD I: Enhanced expression of MHC class I molecules on cultured human thyroid follicular cells infected with reovirus through induction of type 1 interferons. Clin. Exp. Immunol. (1995) 101:121-126.
-
(1995)
Clin. Exp. Immunol.
, vol.101
, pp. 121-126
-
-
Atta, M.S.1
Irving, W.L.2
Powell, R.J.3
Todd, I.4
-
142
-
-
0034006184
-
Reovirus as a novel oncolytic agent
-
NORMAN KL, LEE PW: Reovirus as a novel oncolytic agent. J. Clin. Invest. (2000) 105:1035-1038.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 1035-1038
-
-
Norman, K.L.1
Lee, P.W.2
-
143
-
-
0032526693
-
The molecular basis of viral oncolysis: Usurpation of the Ras signaling pathway by reovirus
-
STRONG JE, COFFEY MC, TANG D, SABININ P, LEE PW: The molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirus. EMBO J. (1998) 17:3351-3362.
-
(1998)
EMBO J.
, vol.17
, pp. 3351-3362
-
-
Strong, J.E.1
Coffey, M.C.2
Tang, D.3
Sabinin, P.4
Lee, P.W.5
-
144
-
-
0025662985
-
Anti-thyroglobulin antibodies induced with recombinant reovirus infection in BALB/c mice
-
ONODERA T, AWAYA A: Anti-thyroglobulin antibodies induced with recombinant reovirus infection in BALB/c mice. Immunology (1990) 71:581-585.
-
(1990)
Immunology
, vol.71
, pp. 581-585
-
-
Onodera, T.1
Awaya, A.2
-
145
-
-
0024358230
-
Direct induction of Ia antigen on murine thyroid-derived epithelial cells by reovirus
-
GAULTON GN, STEIN ME, SAFKO B, STADECKER MJ: Direct induction of Ia antigen on murine thyroid-derived epithelial cells by reovirus. J. Immunol. (1989) 142:3821-3825.
-
(1989)
J. Immunol.
, vol.142
, pp. 3821-3825
-
-
Gaulton, G.N.1
Stein, M.E.2
Safko, B.3
Stadecker, M.J.4
-
146
-
-
0024520439
-
Reovirus induction of MHC class II antigen in rat thyroid cells
-
NEUFELD DS, PLATZER M, DAVIES TF: Reovirus induction of MHC class II antigen in rat thyroid cells. (1989) Endocrinology 124:543-545.
-
(1989)
Endocrinology
, vol.124
, pp. 543-545
-
-
Neufeld, D.S.1
Platzer, M.2
Davies, T.F.3
|