A tandemly repeated thyroglobulin core promoter has potential to enhance efficacy for tissue-specific gene therapy for thyroid carcinomas

Cancer Gene Therapy

Volumn 9, Issue 10, 2002, Pages 864-874

  Takeda, Teiji ^a   Yamazaki, Masanori ^b   Minemura, Kesami ^a   Imai, Yosuke ^c   Inaba, Hidehumi ^a   Suzuki, Satoru ^a   Miyamoto, Takahide ^a   Ichikawa, Kazuo ^a   Kakizawa, Tomoko ^a   Mori, Jun Ichirou ^a   DeGroot, Leslie J ^b   Hashizume, Kiyoshi ^a  

^a SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF CHICAGO   (United States)

^c KISSEI PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Adenovirus; Ganciclovir; Gene therapy; Herpes simplex virus thymidine kinase; Thyroglobulin promoter; Thyroid carcinoma

Indexed keywords

GANCICLOVIR; THYMIDINE KINASE; THYROGLOBULIN;

ADENOVIRUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CANCER SURVIVAL; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; GENE THERAPY; GENETIC TRANSDUCTION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; LIVER INJURY; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; PROMOTER REGION; RAT; TANDEM REPEAT; THYROID CARCINOMA; THYROID FOLLICULAR CARCINOMA; TISSUE SPECIFICITY; UNDIFFERENTIATED CARCINOMA; VIRUS GENE; VIRUS RECOMBINANT;

ADENOVIRIDAE; ALANINE TRANSAMINASE; ANIMALS; ANTIVIRAL AGENTS; ASPARTATE AMINOTRANSFERASES; BETA-GALACTOSIDASE; CELL DIVISION; GANCICLOVIR; GENE THERAPY; GENES, REPORTER; GENETIC VECTORS; HAPLORHINI; HUMANS; MICE; MICE, INBRED BALB C; MICE, NUDE; PROMOTER REGIONS (GENETICS); RATS; SIMPLEXVIRUS; TANDEM REPEAT SEQUENCES; THYMIDINE KINASE; THYROGLOBULIN; THYROID NEOPLASMS;

ADENOVIRIDAE; ANIMALIA; CUCUMBER MOSAIC VIRUS; MUS MUSCULUS; SIMPLEXVIRUS;

EID: 0036788677     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700511     Document Type: Article

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