Effective gene therapy for medullary thyroid carcinoma using recombinant adenovirus inducing tumor-specific expression of interleukin-12

Gene Therapy

Volumn 9, Issue 1, 2002, Pages 64-74

  Yamazaki, M ^a   Zhang, R ^a   Straus, F H ^a   Messina, M ^b   Robinson, B G ^b,c   Hashizume, K ^d   DeGroot, L J ^a  

^a UNIVERSITY OF CHICAGO   (United States)

^b ROYAL NORTH SHORE HOSPITAL   (Australia)

^c UNIVERSITY OF SYDNEY   (Australia)

^d SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Adenovirus; Calcitonin; Gene therapy; Interleukin 12; Medullary thyroid carcinoma; Tissue specific promoter

Indexed keywords

ADENOVIRUS VECTOR; CALCITONIN; INTERLEUKIN 12; LUCIFERASE; PROTEIN P35; PROTEIN P40; PROTEIN SUBUNIT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENICITY; CELL LINE; CONTROLLED STUDY; GENE ACTIVITY; GENE CASSETTE; GENE CONTROL; GENE LOCATION; GENETIC CODE; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PLAQUE FORMING CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; THYROID MEDULLARY CARCINOMA; TUMOR GROWTH; TUMOR IMMUNITY; TUMOR REGRESSION; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; VIRUS RECOMBINANT; VIRUS REPLICATION;

ADENOVIRIDAE; ANIMALS; CALCITONIN; CARCINOMA, MEDULLARY; GENE THERAPY; GENETIC VECTORS; INJECTIONS, INTRALESIONAL; INTERLEUKIN-12; PROMOTER REGIONS (GENETICS); RATS; RATS, INBRED STRAINS; THYROID NEOPLASMS; TUMOR CELLS, CULTURED;

ADENOVIRIDAE; ANIMALIA; DNA VIRUSES; HUMAN ADENOVIRUS TYPE 5; MURINAE;

EID: 85047695680     PISSN: 09697128     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gt.3301617     Document Type: Article

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