Apoptosis via the B cell antigen receptor requires Bax translocation and involves mitochondrial depolarization, cytochrome C release, and caspase-9 activation

European Journal of Immunology

Volumn 34, Issue 7, 2004, Pages 1950-1960

  Eldering, Eric ^a   Mackus, Wendelina J M ^a   Derks, Ingrid A M ^a   Evers, Ludo M ^a   Beuling, Esther ^a   Teeling, Peter ^a   Lens, Susanne M A ^b   van Oers, Marinus H J ^a   van Lier, René A W ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

B cell receptor; Caspase; CD95

Indexed keywords

B LYMPHOCYTE ANTIGEN; BENZYLOXYCARBONYLASPARTYLGLUTAMYLVALYLASPARTYL FLUOROMETHYL KETONE; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; CASPASE 2; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; FAS ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; PROTEIN BAX; PROTEINASE; ANTIGEN; BAX PROTEIN, HUMAN; CASP3 PROTEIN, HUMAN; CASP9 PROTEIN, HUMAN; CASPASE; ONCOPROTEIN; PROTEIN BCL 2;

APOPTOSIS; ARTICLE; CELL LINE; CELL MATURATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME RELEASE; ENZYME SYNTHESIS; EXPERIMENTAL MODEL; GENE TRANSLOCATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MEMBRANE DEPOLARIZATION; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROVIRUS; SIGNAL TRANSDUCTION; B LYMPHOCYTE; CELL MEMBRANE POTENTIAL; CHEMISTRY; DOMINANT GENE; DRUG EFFECT; GENETICS; IMMUNOLOGY; METABOLISM; MITOCHONDRION; PROTEIN TRANSPORT;

ANTIGENS; ANTIGENS, CD95; APOPTOSIS; B-LYMPHOCYTES; BCL-2-ASSOCIATED X PROTEIN; CARBONYL CYANIDE M-CHLOROPHENYL HYDRAZONE; CASPASE 3; CASPASE 9; CASPASES; CELL LINE; CYTOCHROMES C; ENZYME ACTIVATION; GENES, DOMINANT; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIA; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, ANTIGEN, B-CELL;

EID: 3442898222     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200324817     Document Type: Article

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