Mitochondria connects the antigen receptor to effector caspases during B cell receptor-induced apoptosis in normal human B cells

Journal of Immunology

Volumn 163, Issue 9, 1999, Pages 4655-4662

  Berard, Marion ^a   Mondière, Paul ^a   Casamayor Pallejà, Montserrat ^a   Hennino, Ana ^a   Bella, Chantal ^a   Defrance, Thierry ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; LYMPHOCYTE ANTIGEN RECEPTOR;

APOPTOSIS; ARTICLE; B LYMPHOCYTE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; LYMPHOCYTE ACTIVATION; MITOCHONDRION; PRIORITY JOURNAL;

APOPTOSIS; B-LYMPHOCYTES; CASPASE 3; CASPASE 9; CASPASES; CELL CYCLE; CELL DIFFERENTIATION; CELLS, CULTURED; ENZYME ACTIVATION; HUMANS; IMMUNOLOGIC MEMORY; LYMPHOCYTE ACTIVATION; MITOCHONDRIA; PERMEABILITY; PHOSPHATIDYLSERINES; RECEPTORS, ANTIGEN, B-CELL; TONSIL;

EID: 0344563442     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Goodnow, C. C., J. G. Cyster, S. B. Hartley, S. E. Bell, M. P. Cooke, J. I. Healy, S. Akkaraju, J. C. Rathmell, S. L. Pogue, and K. P. Shokat. 1995. Self-tolerance checkpoints in B lymphocyte development. Adv. Immunol. 59:279.
2. Lagresle, C., P. Mondiere, C. Bella, P. H. Krammer, and T. Defrance. 1996. Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosis. J. Exp. Med. 183:1377.
3. Green, D. R., and D. W. Scott. 1994. Activation-induced apoptosis in lymphocytes. Curr. Opin. Immunol. 6:476.
4. Russell, J. H. 1995. Activation-induced death of mature T cells in the regulation of immune responses. Curr. Opin. Immunol. 7:382.
5. Lynch, D. H., F. Ramsdell, and M. R. Alderson. 1995. Fas and FasL in the homeostatic regulation of immune responses. Immunol. Today 16:569.
6. Schulze-Osthoff, K., D. Ferrari, M. Los, S. Wesselborg, and M. E. Peter. 1998. Apoptosis signaling by death receptors. Eur. J. Biochem. 254:439.
7. Kischkel, F. C., S. Hellbardt, I. Behrmann, M. Germer, M. Pawlita, P. H. Krammer, and M. E. Peter. 1995. Cytotoxicity-dependent APO-I (Fas/ CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 14:5579.
8. Stennicke, H. R., and G. S. Salvesen. 1998. Properties of the caspases. Biochim. Biophys. Acta 1387:17.
9. Miller, D. K. 1997. The role of the caspase family of cysteine proteases in apoptosis. Semin. Immunol. 9:35.
10. Medema, J. P., C. Scaffidi, F. C. Kischkel, A. Shevchenko, M. Mann, P. H. Krammer, and M. E. Peter. 1997. FLICE is activated by association with the CD95 death-inducing signaling complex (DISC). EMBO J. 16:2794.
11. Pan, G., K. O'Rourke, A. M. Chinnaiyan, R. Gentz, R. Ebner, J. Ni, and V. M. Dixit. 1997. The receptor for the cytotoxic ligand TRAIL. Science 276:111.
12. Andjelic, S., and H. C. Liou. 1998. Antigen receptor-induced B lymphocyte apoptosis mediated via a protease of the caspase family. Eur. J. Immunol. 28:570.
13. Lens, S. M., B. F. den Drijver, A. J. Potgens, K. Tesselaar, M. H. van Oers, and R. A. van Lier. 1998. Dissection of pathways leading to antigen receptor-induced and Fas/CD95-induced apoptosis in human B cells. J. Immunol. 160:6083.
14. Rickers, A., E. Brockstedt, M. Y. Mapara, A. Otto, B. Dorken, and K. Bommert. 1998. Inhibition of CPP32 blocks surface IgM-mediated apoptosis and D4-GDI cleavage in human BL60 Burkitt lymphoma cells. Eur. J. Immunol. 28:296.
15. Pulendran, B., G. Kannourakis, S. Nouri, K. G. Smith, and G. J. Nossal. 1995. Soluble antigen can cause enhanced apoptosis of germinal-center B cells. Nature 375:331.
16. Pulendran, B., R. van Driel, and G. J. Nossal. 1997. Immunological tolerance in germinal centers. Immunol. Today 18:27.
17. Shokat, K. M., and C. C. Goodnow. 1995. Antigen-induced B-cell death and elimination during germinal-center immune responses. Nature 375:334.
18. Berard, M., M. Casamayor-Pallejà, G. Billian, C. Bella, P. Mondière, and T. Defrance. 1999. Activation sensitizes human memory B cells to BCR-induced apoplosis. Immunology 98:47.
19. Billian, G., P. Mondiere, M. Berard, C. Bella, and T. Defrance. 1997. Antigen receptor-induced apoptosis of human germinal center B cells is targeted to a centrocytic subset. Eur. J. Immunol. 27:405.
20. Feuillard, J., D. Taylor, M. Casamayor-Palleja, G. D. Johnson, and I. C. MacLennan. 1995. Isolation and characteristics of tonsil centroblasts with reference to 1g class switching. Int. Immunol. 7:121.
21. Lee, C., and L. Ernster. 1966. Competition between oxidative phosphorylation and energy-linked pyridine nucleotide transhydrogenation in submitochondrial particles. Biochem. Biophys. Res. Commun. 23:176.
22. Zamzami, N., P. Marchetti, M. Castedo, C. Zanin, J. L. Vayssiere, P. X. Petit, and G. Kroemer. 1995. Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo. J. Exp. Med. 181:1661.
23. Boehme, S. A., and M. J. Lenardo. 1993. Propriocidal apoptosis of mature T lymphocytes occurs at S phase of the cell cycle. Eur. J. Immunol. 23:1552.
24. Schlegel, J., I. Peters, S. Orrenius, D. K. Miller, N. A. Thornberry, T. T. Yamin, and D. W. Nicholson. 1996. CPP32/apopain is a key interleukin 1β converting enzyme-like protease involved in Fas-mediated apoptosis. J. Biol. Chem. 271:1841.
25. Gregory, C. D., C. Dive, S. Henderson, C. A. Smith, G. T. Williams, J. Gordon, and A. B. Rickinson. 1991. Activation of Epstein-Barr virus latent genes protects human B cells from death by apoptosis. Nature 349:612.
26. Li, P., D. Nijhawan, I. Budihardjo, S. M. Srinivasula, M. Ahmad, E. S. Alnemri, and X. Wang. 1997. Cytochrome r and dATP-dependent formation of Apaf-1 caspase-9 complex initiates an apoptotic protease cascade. Cell 91:479.
27. Eguchi, Y., S. Shimizu, and Y. Tsujimoto. 1997. Intracellular ATP levels determine cell death fate by apoptosis or necrosis. Cancer Res. 57:1835.
28. Leist, M., B. Single, A. F. Castoldi, S. Kuhnle, and P. Nicotera. 1997. Intracellular adenosine triphosphate (ATP) concentration: a switch in the decision between apoptosis and necrosis. J. Exp. Med. 185:1481.
29. Cambier, J. C., J. R. Kettman, E. S. Vitetta, and J. W. Uhr. 1976. Differential susceptibility of neonatal and adult murine spleen cells to in vitro induction of B-cell tolerance. J. Exp. Med. 144:293.
30. Nemazee, D., and K. Buerki. 1989. Clonal deletion of autoreactive B lymphocytes in bone marrow chimeras. Proc. Natl. Acad. Sci. USA 86:8039.
31. Galibert, L., N. Burdin, C. Barthelemy, G. Meffre, I. Durand, E. Garcia, P. Garrone, F. Rousset, J. Banchereau, and Y. J. Liu. 1996. Negative selection of human germinal center B cells by prolonged BCR cross-linking. J. Exp. Med. 183:2075.
32. Parry, S. L., J. Hasbold, M. Holman, and G. G. Klaus. 1994. Hypercross-linking surface IgM or IgD receptors on mature B cells induces apoptosis that is reversed by costimulation with IL-4 and anti-CD40. J. Immunol. 152:2821.
33. Graves, J. D., K. E. Draves, A. Craxton, E. G. Krebs, and E. A. Clark. 1998. A comparison of signaling requirements for apoptosis of human B lymphocytes induced by the B cell receptor and CD95/Fas. J. Immunol. 161:168.