Assembly of lysine 63-linked ubiquitin conjugates by phosphorylated α-synuclein implies Lewy body biogenesis

Journal of Biological Chemistry

Volumn 282, Issue 19, 2007, Pages 14558-14566

  Liu, Chao ^a   Fei, Erkang ^a   Jia, Nali ^a   Wang, Hongfeng ^a   Tao, Ruisong ^a   Iwata, Atsushi ^b   Nukina, Nobuyuki ^b   Zhou, Jiangning ^a   Wang, Guanghui ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DISEASES; GENES; MUTAGENESIS; PHOSPHORYLATION;

CYTOPLASMIC; LYSINE; PARKINSON DISEASE (PD); PHOSPHO-MIMIC MUTANT;

PROTEINS;

ALPHA SYNUCLEIN; HYDROGEN PEROXIDE; LYSINE; MUTANT PROTEIN; UBIQUITIN CONJUGATING ENZYME; UBIQUITIN;

ANIMAL CELL; ARTICLE; BIOGENESIS; CONJUGATE; CONTROLLED STUDY; CYTOPLASM; GENE EXPRESSION; LEWY BODY; NEURITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; UBIQUITINATION; WILD TYPE; ANIMAL; CELL CULTURE; CELL FRACTIONATION; CELL INCLUSION; CHEMISTRY; GENETICS; IMMUNOBLOTTING; METABOLISM; MOUSE; MUTATION; NEUROBLASTOMA; PATHOLOGY; PHOSPHORYLATION;

ALPHA-SYNUCLEIN; ANIMALS; IMMUNOBLOTTING; INCLUSION BODIES; LEWY BODIES; LYSINE; MICE; MUTATION; NEUROBLASTOMA; PHOSPHORYLATION; SUBCELLULAR FRACTIONS; TUMOR CELLS, CULTURED; UBIQUITIN;

EID: 34347260686     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M700422200     Document Type: Article

References (53)

1. Dawson, T. M., and Dawson, V. L. (2003) Science 302, 819-822
2. Nussbaum, R. L., and Ellis, C. E. (2003) N. Engl. J. Med. 348, 1356-1364
3. Olanow, C. W., Perl, D. P., DeMartino, G. N., and McNaught, K. S. (2004) Lancet Neurol. 3, 496-503
4. Shults, C. W. (2006) Proc. Natl. Acad. Sci. U. S. A. 103, 1661-1668
5. Gasser, T. (2001) J. Neurol. 248, 833-840
6. Kruger, R., Kuhn, W., Muller, T., Woitalla, D., Graeber, M., Kosel, S., Przuntek, H., Epplen, J. T., Schols, L., and Riess, O. (1998) Nat. Genet. 18, 106-108
7. Polymeropoulos, M. H., Lavedan, C., Leroy, E., Ide, S. E., Dehejia, A., Dutra, A., Pike, B., Root, H., Rubenstein, J., Boyer, R., Stenroos, E. S., Chandrasekharappa, S., Athanassiadou, A., Papapetropoulos, T., Johnson, W. G., Lazzarini, A. M., Duvoisin, R. C., Di Iorio, G., Golbe, L. I., and Nussbaum, R. L. (1997) Science 276, 2045-2047
8. Zarranz, J. J., Alegre, J., Gomez-Esteban, J. C., Lezcano, E., Ros, R., Ampuero, I., Vidal, L., Hoenicka, J., Rodriguez, O., Atares, B., Llorens, V., Gomez Tortosa, E., del Ser, T., Munoz, D. G., and de Yebenes, J. G. (2004) Ann. Neurol. 55, 164-173
9. Spillantini, M. G., Crowther, R. A., Jakes, R., Hasegawa, M., and Goedert, M. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 6469-6473
10. Wakabayashi, K., Yoshimoto, M., Tsuji, S., and Takahashi, H. (1998) Neurosci. Lett. 249, 180-182
11. Wakabayashi, K., Yoshimoto, M., Fukushima, T., Koide, R., Horikawa, Y., Morita, T., and Takahashi, H. (1999) Neuropathol. Appl. Neurobiol. 25, 363-368
12. Jellinger, K. A. (2003) Mov. Disord. 18, Suppl. 6, S2-S12
13. Fujiwara, H., Hasegawa, M., Dohmae, N., Kawashima, A., Masliah, E., Goldberg, M. S., Shen, J., Takio, K., and Iwatsubo, T. (2002) Nat. Cell. Biol. 4, 160-164
14. Yamada, M., Iwatsubo, T., Mizuno, Y., and Mochizuki, H. (2004) J. Neurochem. 91, 451-461
15. Anderson, J. P., Walker, D. E., Goldstein, J. M., de Laat, R., Banducci, K., Caccavello, R. J., Barbour, R., Huang, J., Kling, K., Lee, M., Diep, L., Keim, P. S., Shen, X., Chataway, T., Schlossmacher, M. G., Seubert, P., Schenk, D., Sinha, S., Gai, W. P., and Chilcote, T. J. (2006) J. Biol. Chem. 281, 29739-29752
16. Takahashi, M., Kanuka, H., Fujiwara, H., Koyama, A., Hasegawa, M., Miura, M., and Iwatsubo, T. (2003) Neurosci. Lett. 336, 155-158
17. Chen, L., and Feany, M. B. (2005) Nat. Neurosci. 8, 657-663
18. Hasegawa, M., Fujiwara, H., Nonaka, T., Wakabayashi, K., Takahashi, H., Lee, V. M., Trojanowski, J. Q., Mann, D., and Iwatsubo, T. (2002) J. Biol. Chem. 277, 49071-49076
19. Hershko, A., and Ciechanover, A. (1998) Annu. Rev. Biochem. 67, 425-479
20. Lowe, J., Blanchard, A., Morrell, K., Lennox, G., Reynolds, L., Billett, M., Landon, M., and Mayer, R. J. (1988) J. Pathol. 155, 9-15
21. Sakamoto, M., Uchihara, T., Hayashi, M., Nakamura, A., Kikuchi, E., Mizutani, T., Mizusawa, H., and Hirai, S. (2002) Exp. Neurol. 177, 88-94
22. Weissman, A. M. (2001) Nat. Rev. Mol. Cell. Biol. 2, 169-178
23. Layfield, R., Cavey, J. R., and Lowe, J. (2003) Aging Res. Rev. 2, 343-356
24. Snyder, H., and Wolozin, B. (2004) J. Mol. Neurosci. 24, 425-442
25. Thrower, J. S., Hoffman, L., Rechsteiner, M., and Pickart, C. M. (2000) EMBO J. 19, 94-102
26. Liu, Y., Fallon, L., Lashuel, H. A., Liu, Z., and Lansbury, P. T., Jr. (2002) Cell 111, 209-218
27. Doss-Pepe, E. W., Chen, L., and Madura, K. (2005) J. Biol. Chem. 280, 16619-16624
28. Iwata, A., Maruyama, M., Kanazawa, I., and Nukina, N. (2001) J. Biol. Chem. 276, 45320-45329
29. Smith, W. W., Margolis, R. L., Li, X., Troncoso, J. C., Lee, M. K., Dawson, V. L., Dawson, T. M., Iwatsubo, T., and Ross, C. A. (2005) J. Neurosci. 25, 5544-5552
30. Braak, H., Del Tredici, K., Rub, U., de Vos, R. A., Jansen Steur, E. N., and Braak, E. (2003) Neurobiol. Aging 24, 197-211
31. Pollanen, M. S., Dickson, D. W., and Bergeron, C. (1993) J. Neuropathol. Exp. Neurol. 52, 183-191
32. Gomez-Tortosa, E., Newell, K., Irizarry, M. C., Sanders, J. L., and Hyman, B. T. (2000) Acta Neuropathol. 99, 352-357
33. Snyder, H., Mensah, K., Theisler, C., Lee, J., Matouschek, A., and Wolozin, B. (2003) J. Biol. Chem. 278, 11753-11759
34. Chen, Q., Thorpe, J., and Keller, J. N. (2005) J. Biol. Chem. 280, 30009-30017
35. Amerik, A., Swaminathan, S., Krantz, B. A., Wilkinson, K. D., and Hochstrasser, M. (1997) EMBO J. 16, 4826-4838
36. Piotrowski, J., Beal, R., Hoffman, L., Wilkinson, K. D., Cohen, R. E., and Pickart, C. M. (1997) J. Biol. Chem. 272, 23712-23721
37. Rideout, H. J., and Stefanis, L. (2002) Mol. Cell. Neurosci. 21, 223-238
38. Pronin, A. N., Morris, A. J., Surguchov, A., and Benovic, J. L. (2000) J. Biol. Chem. 275, 26515-26522
39. Okochi, M., Walter, J., Koyama, A., Nakajo, S., Baba, M., Iwatsubo, T., Meijer, L., Kahle, P. J., and Haass, C. (2000) J. Biol. Chem. 275, 390-397
40. von Coelln, R., Thomas, B., Andrabi, S. A., Lim, K. L., Savitt, J. M., Saffary, R., Stirling, W., Bruno, K., Hess, E. J., Lee, M. K., Dawson, V. L., and Dawson, T. M. (2006) J. Neurosci. 26, 3685-3696
41. Nonaka, T., Iwatsubo, T., and Hasegawa, M. (2005) Biochemistry 44, 361-368
42. Liani, E., Eyal, A., Avraham, E., Shemer, R., Szargel, R., Berg, D., Bornemann, A., Riess, O., Ross, C. A., Rott, R., and Engelender, S. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 5500-5505
43. Imai, Y., Soda, M., and Takahashi, R. (2000) J. Biol. Chem. 275, 35661-35664
44. Lim, K. L., Chew, K. C., Tan, J. M., Wang, C., Chung, K. K., Zhang, Y., Tanaka, Y., Smith, W., Engelender, S., Ross, C. A., Dawson, V. L., and Dawson, T. M. (2005) J. Neurosci. 25, 2002-2009
45. Chung, K. K., Zhang, Y., Lim, K. L., Tanaka, Y., Huang, H., Gao, J., Ross, C. A., Dawson, V. L., and Dawson, T. M. (2001) Nat. Med. 7, 1144-1150
46. Sato, S., Chiba, T., Sakata, E., Kato, K., Mizuno, Y., Hattori, N., and Tanaka, K. (2006) EMBO J. 25, 211-221
47. Giasson, B. I., Murray, I. V., Trojanowski, J. Q., and Lee, V. M. (2001) J. Biol. Chem. 276, 2380-2386
48. Conway, K. A., Harper, J. D., and Lansbury, P. T., Jr. (2000) Biochemistry 39, 2552-2563
49. Martin, L. J., Pan, Y., Price, A. C., Sterling, W., Copeland, N. G., Jenkins, N. A., Price, D. L., and Lee, M. K. (2006) J. Neurosci. 26, 41-50
50. Zhang, W., Wang, T., Pei, Z., Miller, D. S., Wu, X., Block, M. L., Wilson, B., Zhang, W., Zhou, Y., Hong, J. S., and Zhang, J. (2005) FASEB J. 19, 533-542
51. Kirik, D., Annett, L. E., Burger, C., Muzyczka, N., Mandel, R. J., and Bjorklund, A. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 2884-2889
52. Eriksen, J. L., Dawson, T. M., Dickson, D. W., and Petrucelli, L. (2003) Neuron 40, 453-456
53. Mezey, E., Dehejia, A., Harta, G., Papp, M. I., Polymeropoulos, M. H., and Brownstein, M. J. (1998) Nat. Med. 4, 755-757