-
1
-
-
0027511827
-
Casein kinase II phosphorylates the synaptic vesicle protein p65
-
Bennett MK, Miller KG, Scheller RH (1993) Casein kinase II phosphorylates the synaptic vesicle protein p65. J Neurosci 13:1701-1707.
-
(1993)
J Neurosci
, vol.13
, pp. 1701-1707
-
-
Bennett, M.K.1
Miller, K.G.2
Scheller, R.H.3
-
2
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
Braak H, Del TK, Rub U, de Vos RA, Jansen SEN, Braak E (2003) Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging 24:197-211.
-
(2003)
Neurobiol Aging
, vol.24
, pp. 197-211
-
-
Braak, H.1
Del, T.K.2
Rub, U.3
De Vos, R.A.4
Jansen, S.E.N.5
Braak, E.6
-
3
-
-
0037726598
-
Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1
-
Chen HK, Fernandez-Funez P, Acevedo SF, Lam YC, Kaytor MD, Fernandez MH, Aitken A, Skoulakis EM, Orr HT, Botas J, Zoghbi HY (2003) Interaction of Akt-phosphorylated ataxin-1 with 14-3-3 mediates neurodegeneration in spinocerebellar ataxia type 1. Cell 113:457-468.
-
(2003)
Cell
, vol.113
, pp. 457-468
-
-
Chen, H.K.1
Fernandez-Funez, P.2
Acevedo, S.F.3
Lam, Y.C.4
Kaytor, M.D.5
Fernandez, M.H.6
Aitken, A.7
Skoulakis, E.M.8
Orr, H.T.9
Botas, J.10
Zoghbi, H.Y.11
-
4
-
-
0034776095
-
Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: Implications for Lewy-body formation in Parkinson disease
-
Chung KK, Zhang Y, Lim KL, Tanaka Y, Huang H, Gao J, Ross CA, Dawson VL, Dawson TM (2001a) Parkin ubiquitinates the alpha-synuclein-interacting protein, synphilin-1: implications for Lewy-body formation in Parkinson disease. Nat Med 7:1144-1150.
-
(2001)
Nat Med
, vol.7
, pp. 1144-1150
-
-
Chung, K.K.1
Zhang, Y.2
Lim, K.L.3
Tanaka, Y.4
Huang, H.5
Gao, J.6
Ross, C.A.7
Dawson, V.L.8
Dawson, T.M.9
-
5
-
-
2942618660
-
The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders
-
Chung KK, Dawson VL, Dawson TM (2001b) The role of the ubiquitin-proteasomal pathway in Parkinson's disease and other neurodegenerative disorders. Trends Neurosci 24:37-14.
-
(2001)
Trends Neurosci
, vol.24
, pp. 37-14
-
-
Chung, K.K.1
Dawson, V.L.2
Dawson, T.M.3
-
6
-
-
0242363670
-
Molecular pathways of neurodegeneration in Parkinson's disease
-
Dawson TM, Dawson VL (2003) Molecular pathways of neurodegeneration in Parkinson's disease. Science 302:819-822.
-
(2003)
Science
, vol.302
, pp. 819-822
-
-
Dawson, T.M.1
Dawson, V.L.2
-
7
-
-
0028916490
-
Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase I in vitro and in vivo
-
Desdouits F, Cohen D, Nairn AC, Greengard P, Girault JA (1995) Phosphorylation of DARPP-32, a dopamine- and cAMP-regulated phosphoprotein, by casein kinase I in vitro and in vivo. J Biol Chem 270:8772-8778.
-
(1995)
J Biol Chem
, vol.270
, pp. 8772-8778
-
-
Desdouits, F.1
Cohen, D.2
Nairn, A.C.3
Greengard, P.4
Girault, J.A.5
-
8
-
-
0038460184
-
Part II: Alpha-synuclein and its molecular pathophysiological role in neurodegenerative disease
-
Dev KK, Hofele K, Barbieri S, Buchman VL, van der PH (2003) Part II: alpha-synuclein and its molecular pathophysiological role in neurodegenerative disease. Neuropharmacology 45:14-44.
-
(2003)
Neuropharmacology
, vol.45
, pp. 14-44
-
-
Dev, K.K.1
Hofele, K.2
Barbieri, S.3
Buchman, V.L.4
Van Der, P.H.5
-
9
-
-
0037846441
-
Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice
-
Emamian ES, Kaytor MD, Duvick LA, Zu T, Tousey SK, Zoghbi HY, Clark HB, Orr HT (2003) Serine 776 of ataxin-1 is critical for polyglutamine-induced disease in SCA1 transgenic mice. Neuron 38:375-387.
-
(2003)
Neuron
, vol.38
, pp. 375-387
-
-
Emamian, E.S.1
Kaytor, M.D.2
Duvick, L.A.3
Zu, T.4
Tousey, S.K.5
Zoghbi, H.Y.6
Clark, H.B.7
Orr, H.T.8
-
10
-
-
0032952414
-
Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions
-
Engelender S, Kaminsky Z, Guo X, Sharp AH, Amaravi RK, Kleiderlein JJ, Margolis RL, Troncoso JC, Lanahan AA, Worley PF, Dawson VL, Dawson TM, Ross CA (1999) Synphilin-1 associates with alpha-synuclein and promotes the formation of cytosolic inclusions. Nat Genet 22:110-114.
-
(1999)
Nat Genet
, vol.22
, pp. 110-114
-
-
Engelender, S.1
Kaminsky, Z.2
Guo, X.3
Sharp, A.H.4
Amaravi, R.K.5
Kleiderlein, J.J.6
Margolis, R.L.7
Troncoso, J.C.8
Lanahan, A.A.9
Worley, P.F.10
Dawson, V.L.11
Dawson, T.M.12
Ross, C.A.13
-
11
-
-
2642607011
-
Low frequency of alpha-synuclein mutations in familial Parkinson's disease
-
Farrer M, Wavrant-De Vrieze F, Crook R, Boles L, Perez-Tur J, Hardy J, Johnson WG, Steele J, Maraganore D, Gwinn K, Lynch T (1998) Low frequency of alpha-synuclein mutations in familial Parkinson's disease. Ann Neurol 43:394-397.
-
(1998)
Ann Neurol
, vol.43
, pp. 394-397
-
-
Farrer, M.1
Wavrant-De Vrieze, F.2
Crook, R.3
Boles, L.4
Perez-Tur, J.5
Hardy, J.6
Johnson, W.G.7
Steele, J.8
Maraganore, D.9
Gwinn, K.10
Lynch, T.11
-
12
-
-
0034626735
-
Oxidants, oxidative stress and the biology of ageing
-
Finkel T, Holbrook NJ (2000) Oxidants, oxidative stress and the biology of ageing. Nature 408:239-247.
-
(2000)
Nature
, vol.408
, pp. 239-247
-
-
Finkel, T.1
Holbrook, N.J.2
-
13
-
-
7044238416
-
Neurodegenerative diseases: A decade of discoveries paves the way for therapeutic breakthroughs
-
Forman MS, Trojanowski JQ, Lee VM (2004) Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs. Nat Med 10:1055-1063.
-
(2004)
Nat Med
, vol.10
, pp. 1055-1063
-
-
Forman, M.S.1
Trojanowski, J.Q.2
Lee, V.M.3
-
14
-
-
0036174010
-
Alpha-synuclein is phosphorylated in synucleinopathy lesions
-
Fujiwara H, Hasegawa M, Dohmae N, Kawashima A, Masliah E, Goldberg MS, Shen J, Takio K, Iwatsubo T (2002) Alpha-synuclein is phosphorylated in synucleinopathy lesions. Nat Cell Biol 4:160-164.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 160-164
-
-
Fujiwara, H.1
Hasegawa, M.2
Dohmae, N.3
Kawashima, A.4
Masliah, E.5
Goldberg, M.S.6
Shen, J.7
Takio, K.8
Iwatsubo, T.9
-
15
-
-
0032608987
-
Pathobiology of the Lewy body
-
Galvin JE, Lee VM, Schmidt ML, Tu PH, Iwatsubo T, Trojanowski JQ (1999) Pathobiology of the Lewy body. Adv Neurol 80:313-324.
-
(1999)
Adv Neurol
, vol.80
, pp. 313-324
-
-
Galvin, J.E.1
Lee, V.M.2
Schmidt, M.L.3
Tu, P.H.4
Iwatsubo, T.5
Trojanowski, J.Q.6
-
16
-
-
0034602442
-
Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions
-
Giasson BI, Duda JE, Murray IV, Chen Q, Souza JM, Hurtig HI, Ischiropoulos H, Trojanowski JQ, Lee VM (2000) Oxidative damage linked to neurodegeneration by selective alpha-synuclein nitration in synucleinopathy lesions. Science 290:985-989.
-
(2000)
Science
, vol.290
, pp. 985-989
-
-
Giasson, B.I.1
Duda, J.E.2
Murray, I.V.3
Chen, Q.4
Souza, J.M.5
Hurtig, H.I.6
Ischiropoulos, H.7
Trojanowski, J.Q.8
Lee, V.M.9
-
17
-
-
0025976482
-
Neuronal inclusions of Parkinson's disease
-
Gibb WR, Scott T, Lees AJ (1991) Neuronal inclusions of Parkinson's disease. Mov Disord 6:2-11.
-
(1991)
Mov Disord
, vol.6
, pp. 2-11
-
-
Gibb, W.R.1
Scott, T.2
Lees, A.J.3
-
18
-
-
14844335694
-
The E46K mutation in alpha-synuclein increases amyloid fibril formation
-
Greenbaum EA, Graves CL, Mishizen-Eberz AJ, Lupoli MA, Lynch DR, Englander SW, Axelsen PH, Giasson BI (2005) The E46K mutation in alpha-synuclein increases amyloid fibril formation. J Biol Chem 280:7800-7807.
-
(2005)
J Biol Chem
, vol.280
, pp. 7800-7807
-
-
Greenbaum, E.A.1
Graves, C.L.2
Mishizen-Eberz, A.J.3
Lupoli, M.A.4
Lynch, D.R.5
Englander, S.W.6
Axelsen, P.H.7
Giasson, B.I.8
-
19
-
-
0029086047
-
A phosphatidylinositol 4,5-bisphosphate-sensitive casein kinase I alpha associates with synaptic vesicles and phosphorylates a subset of vesicle proteins
-
Gross SD, Hoffman DP, Fisette PL, Baas P, Anderson RA (1995) A phosphatidylinositol 4,5-bisphosphate-sensitive casein kinase I alpha associates with synaptic vesicles and phosphorylates a subset of vesicle proteins. J Cell Biol 130:711-724.
-
(1995)
J Cell Biol
, vol.130
, pp. 711-724
-
-
Gross, S.D.1
Hoffman, D.P.2
Fisette, P.L.3
Baas, P.4
Anderson, R.A.5
-
20
-
-
2242472974
-
Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesions
-
Hasegawa M, Fujiwara H, Nonaka T, Wakabayashi K, Takahashi H, Lee VM, Trojanowski JQ, Mann D, Iwatsubo T (2002) Phosphorylated alpha-synuclein is ubiquitinated in alpha-synucleinopathy lesions. J Biol Chem 277:49071-49076.
-
(2002)
J Biol Chem
, vol.277
, pp. 49071-49076
-
-
Hasegawa, M.1
Fujiwara, H.2
Nonaka, T.3
Wakabayashi, K.4
Takahashi, H.5
Lee, V.M.6
Trojanowski, J.Q.7
Mann, D.8
Iwatsubo, T.9
-
21
-
-
0033577159
-
Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synudein in vitro
-
Hashimoto M, Hsu LJ, Xia Y, Takeda A, Sisk A, Sundsmo M, Masliah E (1999) Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synudein in vitro. NeuroReport 10:717-721.
-
(1999)
NeuroReport
, vol.10
, pp. 717-721
-
-
Hashimoto, M.1
Hsu, L.J.2
Xia, Y.3
Takeda, A.4
Sisk, A.5
Sundsmo, M.6
Masliah, E.7
-
22
-
-
0037118247
-
Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila
-
Jackson GR, Wiedau-Pazos M, Sang TK, Wagle N, Brown CA, Massachi S, Geschwind DH (2002) Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila. Neuron 34:509-519.
-
(2002)
Neuron
, vol.34
, pp. 509-519
-
-
Jackson, G.R.1
Wiedau-Pazos, M.2
Sang, T.K.3
Wagle, N.4
Brown, C.A.5
Massachi, S.6
Geschwind, D.H.7
-
23
-
-
0035191413
-
Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model
-
Kahle PJ, Neumann M, Ozmen L, Muller V, Odoy S, Okamoto N, Jacobsen H, Iwatsubo T, Trojanowski JQ, Takahashi H, Wakabayashi K, Bogdanovic N, Riederer P, Kretzschmar HA, Haass C (2001) Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model. Am J Pathol 159:2215-2225.
-
(2001)
Am J Pathol
, vol.159
, pp. 2215-2225
-
-
Kahle, P.J.1
Neumann, M.2
Ozmen, L.3
Muller, V.4
Odoy, S.5
Okamoto, N.6
Jacobsen, H.7
Iwatsubo, T.8
Trojanowski, J.Q.9
Takahashi, H.10
Wakabayashi, K.11
Bogdanovic, N.12
Riederer, P.13
Kretzschmar, H.A.14
Haass, C.15
-
24
-
-
0036304315
-
Hyperphosphorylation and insolubility of alpha-synuclein in transgenic mouse oligodendrocytes
-
Kahle PJ, Neumann M, Ozmen L, Muller V, Jacobsen H, Spooren W, Fuss B, Mallon B, Macklin WB, Fujiwara H, Hasegawa M, Iwatsubo T, Kretzschmar HA, Haass C (2002) Hyperphosphorylation and insolubility of alpha-synuclein in transgenic mouse oligodendrocytes. EMBO Rep 3:583-588.
-
(2002)
EMBO Rep
, vol.3
, pp. 583-588
-
-
Kahle, P.J.1
Neumann, M.2
Ozmen, L.3
Muller, V.4
Jacobsen, H.5
Spooren, W.6
Fuss, B.7
Mallon, B.8
Macklin, W.B.9
Fujiwara, H.10
Hasegawa, M.11
Iwatsubo, T.12
Kretzschmar, H.A.13
Haass, C.14
-
25
-
-
0034008852
-
Enhanced vulnerability to oxidative stress by alpha-synuclein mutations and C-terminal truncation
-
Kanda S, Bishop JF, Eglitis MA, Yang Y, Mouradian MM (2000) Enhanced vulnerability to oxidative stress by alpha-synuclein mutations and C-terminal truncation. Neuroscience 97:279-284.
-
(2000)
Neuroscience
, vol.97
, pp. 279-284
-
-
Kanda, S.1
Bishop, J.F.2
Eglitis, M.A.3
Yang, Y.4
Mouradian, M.M.5
-
27
-
-
0031990490
-
30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat Genet 18:106-108.
-
(1998)
Nat Genet
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
Przuntek, H.7
Epplen, J.T.8
Schols, L.9
Riess, O.10
-
28
-
-
1342325420
-
Casein kinase II-mediated phosphorylation regulates alpha-synuclein/ synphilin-1 interaction and inclusion body formation
-
Lee G, Tanaka M, Park K, Lee SS, Kim YM, Junn E, Lee SH, Mouradian MM (2004) Casein kinase II-mediated phosphorylation regulates alpha-synuclein/ synphilin-1 interaction and inclusion body formation. J Biol Chem 279:6834-6839.
-
(2004)
J Biol Chem
, vol.279
, pp. 6834-6839
-
-
Lee, G.1
Tanaka, M.2
Park, K.3
Lee, S.S.4
Kim, Y.M.5
Junn, E.6
Lee, S.H.7
Mouradian, M.M.8
-
29
-
-
0037085288
-
Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors
-
Lee HJ, Shin SY, Choi C, Lee YH, Lee SJ (2002) Formation and removal of alpha-synuclein aggregates in cells exposed to mitochondrial inhibitors. J Biol Chem 277:5411-5417.
-
(2002)
J Biol Chem
, vol.277
, pp. 5411-5417
-
-
Lee, H.J.1
Shin, S.Y.2
Choi, C.3
Lee, Y.H.4
Lee, S.J.5
-
31
-
-
20044386298
-
Parkin mediates non-classic, proteasomal-independent, ubiquitination of spynphilin-1: Implication for Lewy body formation
-
Lim KL, Chew KCM, Tan JMM, Wang C, Chung KK, Tanaka Y, Smith W, Engelender S, Ross CA, Dawson VL, Dawson TM (2005) Parkin mediates non-classic, proteasomal-independent, ubiquitination of spynphilin-1:implication for Lewy body formation. J Neurosci 25:2002-2009.
-
(2005)
J Neurosci
, vol.25
, pp. 2002-2009
-
-
Lim, K.L.1
Chew, K.C.M.2
Tan, J.M.M.3
Wang, C.4
Chung, K.K.5
Tanaka, Y.6
Smith, W.7
Engelender, S.8
Ross, C.A.9
Dawson, V.L.10
Dawson, T.M.11
-
32
-
-
0035863188
-
Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice
-
Lucas JJ, Hernandez F, Gomez-Ramos P, Moran MA, Hen R, Avila J (2001) Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice. EMBO J 20:27-39.
-
(2001)
EMBO J
, vol.20
, pp. 27-39
-
-
Lucas, J.J.1
Hernandez, F.2
Gomez-Ramos, P.3
Moran, M.A.4
Hen, R.5
Avila, J.6
-
33
-
-
0036855635
-
Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies
-
Neumann M, Kahle PJ, Giasson BI, Ozmen L, Borroni E, Spooren W, Muller V, Odoy S, Fujiwara H, Hasegawa M, Iwatsubo T, Trojanowski JQ, Kretzschmar HA, Haass C (2002) Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies. J Clin Invest 110:1429-1439.
-
(2002)
J Clin Invest
, vol.110
, pp. 1429-1439
-
-
Neumann, M.1
Kahle, P.J.2
Giasson, B.I.3
Ozmen, L.4
Borroni, E.5
Spooren, W.6
Muller, V.7
Odoy, S.8
Fujiwara, H.9
Hasegawa, M.10
Iwatsubo, T.11
Trojanowski, J.Q.12
Kretzschmar, H.A.13
Haass, C.14
-
34
-
-
0034614415
-
Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein
-
Okochi M, Walter J, Koyama A, Nakajo S, Baba M, Iwatsubo T, Meijer L, Kahle PJ, Haass C (2000) Constitutive phosphorylation of the Parkinson's disease associated alpha-synuclein. J Biol Chem 275:390-397.
-
(2000)
J Biol Chem
, vol.275
, pp. 390-397
-
-
Okochi, M.1
Walter, J.2
Koyama, A.3
Nakajo, S.4
Baba, M.5
Iwatsubo, T.6
Meijer, L.7
Kahle, P.J.8
Haass, C.9
-
36
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E, Ide SE, Dehejia A, Dutra A, Pike B, Root H, Rubenstein J, Boyer R, Stenroos ES, Chandrasekharappa S, Athanassiadou A, Papapetropoulos T, Johnson WG, Lazzarini AM, Duvoisin RC, Di Iorio G, Golbe LI, Nussbaum RL (1997) Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 276:2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
37
-
-
0034714204
-
Synucleins are a novel class of substrates for G protein-coupled receptor kinases
-
Pronin AN, Morris AJ, Surguchov A, Benovic JL (2000) Synucleins are a novel class of substrates for G protein-coupled receptor kinases. J Biol Chem 275:26515-26522.
-
(2000)
J Biol Chem
, vol.275
, pp. 26515-26522
-
-
Pronin, A.N.1
Morris, A.J.2
Surguchov, A.3
Benovic, J.L.4
-
38
-
-
8744311814
-
alpha-Synuclein is required for the fibrillar nature of ubiquitinated inclusions induced by proteasomal inhibition in primary neurons
-
Rideout HJ, Dietrich P, Wang Q, Dauer WT, Stefanis L (2004) alpha-Synuclein is required for the fibrillar nature of ubiquitinated inclusions induced by proteasomal inhibition in primary neurons. J Biol Chem 279:46915-46920.
-
(2004)
J Biol Chem
, vol.279
, pp. 46915-46920
-
-
Rideout, H.J.1
Dietrich, P.2
Wang, Q.3
Dauer, W.T.4
Stefanis, L.5
-
39
-
-
0036095285
-
Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies
-
Schlossmacher MG, Frosch MP, Gai WP, Medina M, Sharma N, Forno L, Ochiishi T, Shimura H, Sharon R, Hattori N, Langston JW, Mizuno Y, Hyman BT, Selkoe DJ, Kosik KS (2002) Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies. Am J Pathol 160:1655-1667.
-
(2002)
Am J Pathol
, vol.160
, pp. 1655-1667
-
-
Schlossmacher, M.G.1
Frosch, M.P.2
Gai, W.P.3
Medina, M.4
Sharma, N.5
Forno, L.6
Ochiishi, T.7
Shimura, H.8
Sharon, R.9
Hattori, N.10
Langston, J.W.11
Mizuno, Y.12
Hyman, B.T.13
Selkoe, D.J.14
Kosik, K.S.15
-
40
-
-
0035854437
-
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: Implications for Parkinson's disease
-
Shimura H, Schlossmacher MG, Hattori N, Frosch MP, Trockenbacher A, Schneider R, Mizuno Y, Kosik KS, Selkoe DJ (2001) Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease. Science 293:263-269.
-
(2001)
Science
, vol.293
, pp. 263-269
-
-
Shimura, H.1
Schlossmacher, M.G.2
Hattori, N.3
Frosch, M.P.4
Trockenbacher, A.5
Schneider, R.6
Mizuno, Y.7
Kosik, K.S.8
Selkoe, D.J.9
-
41
-
-
0034531475
-
The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy
-
Spillantini MG, Goedert M (2000) The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. Ann NY Acad Sci 920;16-27:16-27.
-
(2000)
Ann NY Acad Sci
, vol.920
, pp. 16-27
-
-
Spillantini, M.G.1
Goedert, M.2
-
42
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
Spillantini MG, Schmidt ML, Lee VM, Trojanowski JQ, Jakes R, Goedert M (1997) Alpha-synuclein in Lewy bodies. Nature 388:839-840.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
43
-
-
0032568534
-
alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies
-
Spillantini MG, Crowther RA, Jakes R, Hasegawa M, Goedert M (1998) alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc Natl Acad Sci USA 95:6469-6473.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6469-6473
-
-
Spillantini, M.G.1
Crowther, R.A.2
Jakes, R.3
Hasegawa, M.4
Goedert, M.5
-
44
-
-
0037461582
-
Phosphorylation of alpha-synuclein characteristic of synucleinopathy lesions is recapitulated in alpha-synuclein transgenic Drosophila
-
Takahashi M, Kanuka H, Fujiwara H, Koyama A, Hasegawa M, Miura M, Iwatsubo T (2003) Phosphorylation of alpha-synuclein characteristic of synucleinopathy lesions is recapitulated in alpha-synuclein transgenic Drosophila. Neurosci Lett 336:155-158.
-
(2003)
Neurosci Lett
, vol.336
, pp. 155-158
-
-
Takahashi, M.1
Kanuka, H.2
Fujiwara, H.3
Koyama, A.4
Hasegawa, M.5
Miura, M.6
Iwatsubo, T.7
-
45
-
-
1042266326
-
Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective
-
Tanaka M, Kim YM, Lee G, Junn E, Iwatsubo T, Mouradian MM (2004) Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective. J Biol Chem 279:4625-4631.
-
(2004)
J Biol Chem
, vol.279
, pp. 4625-4631
-
-
Tanaka, M.1
Kim, Y.M.2
Lee, G.3
Junn, E.4
Iwatsubo, T.5
Mouradian, M.M.6
-
46
-
-
0035870881
-
Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
-
Tanaka Y, Engelender S, Igarashi S, Rao RK, Wanner T, Tanzi RE, Sawa A, Dawson L, Dawson TM, Ross CA (2001) Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. Hum Mol Genet 10:919-926.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 919-926
-
-
Tanaka, Y.1
Engelender, S.2
Igarashi, S.3
Rao, R.K.4
Wanner, T.5
Tanzi, R.E.6
Sawa, A.7
Dawson, L.8
Dawson, T.M.9
Ross, C.A.10
-
47
-
-
0028290651
-
Association of casein kinase 2 with nuclear matrix. Possible role in nuclear matrix protein phosphorylation
-
Tawfic S, Ahmed K (1994) Association of casein kinase 2 with nuclear matrix. Possible role in nuclear matrix protein phosphorylation. J Biol Chem 269:7489-7493.
-
(1994)
J Biol Chem
, vol.269
, pp. 7489-7493
-
-
Tawfic, S.1
Ahmed, K.2
-
48
-
-
0037077040
-
Toxic proteins in neurodegenerative disease
-
Taylor JP, Hardy J, Fischbeck KH (2002) Toxic proteins in neurodegenerative disease. Science 296:1991-1995.
-
(2002)
Science
, vol.296
, pp. 1991-1995
-
-
Taylor, J.P.1
Hardy, J.2
Fischbeck, K.H.3
-
49
-
-
0026039891
-
Casein kinase I and II-multipotential serine protein kinases: Structure, function, and regulation
-
Tuazon PT, Traugh JA (1991) Casein kinase I and II-multipotential serine protein kinases: structure, function, and regulation. Adv Second Messenger Phosphoprotein Res 23:123-164.
-
(1991)
Adv Second Messenger Phosphoprotein Res
, vol.23
, pp. 123-164
-
-
Tuazon, P.T.1
Traugh, J.A.2
-
50
-
-
0027489773
-
Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease
-
Ueda K, Fukushima H, Masliah E, Xia Y, Iwai A, Yoshimoto M, Otero DA, Kondo J, Ihara Y, Saitoh T (1993) Molecular cloning of cDNA encoding an unrecognized component of amyloid in Alzheimer disease. Proc Natl Acad Sci USA 90:11282-11286.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 11282-11286
-
-
Ueda, K.1
Fukushima, H.2
Masliah, E.3
Xia, Y.4
Iwai, A.5
Yoshimoto, M.6
Otero, D.A.7
Kondo, J.8
Ihara, Y.9
Saitoh, T.10
-
51
-
-
0034085796
-
Synphilin-1 is present in Lewy bodies in Parkinson's disease
-
Wakabayashi K, Engelender S, Yoshimoto M, Tsuji S, Ross CA, Takahashi H (2000) Synphilin-1 is present in Lewy bodies in Parkinson's disease. Ann Neurol 47:521-523.
-
(2000)
Ann Neurol
, vol.47
, pp. 521-523
-
-
Wakabayashi, K.1
Engelender, S.2
Yoshimoto, M.3
Tsuji, S.4
Ross, C.A.5
Takahashi, H.6
-
52
-
-
10744230149
-
The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia
-
Zarranz JJ, Alegre J, Gomez-Esteban JC, Lezcano E, Ros R, Ampuero I, Vidal L, Hoenicka J, Rodriguez O, Atares B, Llorens V, Gomez TE, del Ser T, Munoz DG, de Yebenes JG (2004) The new mutation, E46K, of alpha-synuclein causes Parkinson and Lewy body dementia. Ann Neurol 55:164-173.
-
(2004)
Ann Neurol
, vol.55
, pp. 164-173
-
-
Zarranz, J.J.1
Alegre, J.2
Gomez-Esteban, J.C.3
Lezcano, E.4
Ros, R.5
Ampuero, I.6
Vidal, L.7
Hoenicka, J.8
Rodriguez, O.9
Atares, B.10
Llorens, V.11
Gomez, T.E.12
Del Ser, T.13
Munoz, D.G.14
De Yebenes, J.G.15
-
53
-
-
0033825627
-
Oxidative stress and genetics in the pathogenesis of Parkinson's disease
-
Zhang Y, Dawson VL, Dawson TM (2000) Oxidative stress and genetics in the pathogenesis of Parkinson's disease. Neurobiol Dis 7:240-250.
-
(2000)
Neurobiol Dis
, vol.7
, pp. 240-250
-
-
Zhang, Y.1
Dawson, V.L.2
Dawson, T.M.3
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