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Brand-Herrmann S-M, Kuznetsova T, Wiechert A, et al. Alcohol intake modulates the genetic association between HDL cholesterol and the PPARγ2 Pro12Ala polymorphism. J Lipid Res 2005; 46:913-919.
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Brand-Herrmann, S.-M.1
Kuznetsova, T.2
Wiechert, A.3
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Influence of Pro12Ala peroxisome proliferator-activated receptor gamma2 polymorphism on glucose response to exercise training in type 2 diabetes
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Adamo KB, Sigal RJ, Williams K, et al. Influence of Pro12Ala peroxisome proliferator-activated receptor gamma2 polymorphism on glucose response to exercise training in type 2 diabetes. Diabetologia 2005; 48:1503-1509.
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Diabetologia
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Adamo, K.B.1
Sigal, R.J.2
Williams, K.3
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Endurance training-induced changes in the insulin response to oral glucose are associated with the peroxisome proliferator-activated receptor-γ2 Pro12Ala genotype in men but not in women
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Weiss EP, Kulaputana O, Ghiu IA, et al. Endurance training-induced changes in the insulin response to oral glucose are associated with the peroxisome proliferator-activated receptor-γ2 Pro12Ala genotype in men but not in women. Metabolism 2005; 54:97-102.
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Metabolism
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Weiss, E.P.1
Kulaputana, O.2
Ghiu, I.A.3
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Association of the Pro12Ala polymorphism in the PPAR-γ2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study
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Lindi VI, Uusitupa MI, Lindstrom J, et al. Association of the Pro12Ala polymorphism in the PPAR-γ2 gene with 3-year incidence of type 2 diabetes and body weight change in the Finnish Diabetes Prevention Study. Diabetes 2002; 51:2581-2586.
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Lindi, V.I.1
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Lindstrom, J.3
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Florez JC, Jablonski AK, Sun MW. Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone. J Clin Endocrinol Metab 2007; 92:1502-1509. A large-scale intervention study of type 2 diabetes including more than 3500 participants with impaired glucose tolerance. No interaction of PPARG Pro12Ala genotype with lifestyle intervention or medical treatment on progression to type 2 diabetes is observed.
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Florez JC, Jablonski AK, Sun MW. Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone. J Clin Endocrinol Metab 2007; 92:1502-1509. A large-scale intervention study of type 2 diabetes including more than 3500 participants with impaired glucose tolerance. No interaction of PPARG Pro12Ala genotype with lifestyle intervention or medical treatment on progression to type 2 diabetes is observed.
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53
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de Rooij SR, Painter RC, Phillips DI, et al. Impaired insulin secretion after prenatal exposure to the Dutch famine. Diabetes Care 2006; 29:1052-1057. A most interesting study of a unique birth cohort exposed to prenatal famine during World War II. The paper shows that the effect of PPARG Pro12Ala genotype on type 2 diabetes and insulin secretion is modulated by prenatal exposure to famine during mid-gestation.
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de Rooij SR, Painter RC, Phillips DI, et al. Impaired insulin secretion after prenatal exposure to the Dutch famine. Diabetes Care 2006; 29:1052-1057. A most interesting study of a unique birth cohort exposed to prenatal famine during World War II. The paper shows that the effect of PPARG Pro12Ala genotype on type 2 diabetes and insulin secretion is modulated by prenatal exposure to famine during mid-gestation.
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54
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The effects of the Pro12Ala polymorphism of the PPARγ-2 gene on lipid metabolism interact with body size at birth
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Eriksson J, Lindi V, Uusitopa M, et al. The effects of the Pro12Ala polymorphism of the PPARγ-2 gene on lipid metabolism interact with body size at birth. Clin Genet 2003; 64:366-370.
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Clin Genet
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Eriksson, J.1
Lindi, V.2
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55
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Grant SF, Thorleifsson G, Reynisdottir I, et al. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 2006; 38:320-323. The original paper from deCODE genetics describing the observation of TCF7L2 as a type 2 diabetes susceptibility gene. Includes independent replication of significant findings.
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Grant SF, Thorleifsson G, Reynisdottir I, et al. Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes. Nat Genet 2006; 38:320-323. The original paper from deCODE genetics describing the observation of TCF7L2 as a type 2 diabetes susceptibility gene. Includes independent replication of significant findings.
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56
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Groves CJ, Zeggini E, Minton J, et al. Association analysis of 6 736 U. K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk. Diabetes 2006; 55:2640-2644.
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Groves CJ, Zeggini E, Minton J, et al. Association analysis of 6 736 U. K. subjects provides replication and confirms TCF7L2 as a type 2 diabetes susceptibility gene with a substantial effect on individual risk. Diabetes 2006; 55:2640-2644.
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Helgason A, Palsson S, Thorleifsson G, et al. Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. Nat Genet 2007; 39:218-225. An interesting study refining the association of variation in TCF7L2 with type 2 diabetes.
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Helgason A, Palsson S, Thorleifsson G, et al. Refining the impact of TCF7L2 gene variants on type 2 diabetes and adaptive evolution. Nat Genet 2007; 39:218-225. An interesting study refining the association of variation in TCF7L2 with type 2 diabetes.
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58
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Florez JC, Jablonski AK, Bayley N, et al. TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N Engl JMed 2006; 355:241-250. A large-scale intervention study of type 2 diabetes including more than 3500 participants with impaired glucose tolerance. Describes the relationship between lifestyle intervention, TCF7L2 genotypes and progression to type 2 diabetes.
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Florez JC, Jablonski AK, Bayley N, et al. TCF7L2 polymorphisms and progression to diabetes in the Diabetes Prevention Program. N Engl JMed 2006; 355:241-250. A large-scale intervention study of type 2 diabetes including more than 3500 participants with impaired glucose tolerance. Describes the relationship between lifestyle intervention, TCF7L2 genotypes and progression to type 2 diabetes.
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59
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0242515957
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The detection of gene-environment interaction for continuous traits: Should we deal with measurement error by bigger studies or better measurement?
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Wong MY, Day NE, Luan JA, et al. The detection of gene-environment interaction for continuous traits: should we deal with measurement error by bigger studies or better measurement? Int J Epidemiol 2003; 32:51-57.
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Int J Epidemiol
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Wong, M.Y.1
Day, N.E.2
Luan, J.A.3
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