Dietary fat intake determines the effect of a common polymorphism in the hepatic lipase gene promoter on high-density lipoprotein metabolism: Evidence of a strong dose effect in this gene-nutrient interaction in the Framingham study

Circulation

Volumn 106, Issue 18, 2002, Pages 2315-2321

  Ordovas, Jose M ^a   Corella, Dolores ^a   Demissie, Serkalem ^a   Cupples, L Adrienne ^a   Couture, Patrick ^a   Coltell, Oscar ^a   Wilson, Peter W F ^a   Schaefer, Ernst J ^a   Tucker, Katherine L ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

Diet; Fatty acids; Genetics; Lipids; Lipoproteins

Indexed keywords

FATTY ACID; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LIPOPROTEIN; LIVER TRIACYLGLYCEROL LIPASE; POLYUNSATURATED FATTY ACID;

ADAPTATION; ADULT; ALLELE; ARTICLE; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CONTROLLED STUDY; DIET; DOSE RESPONSE; FAT INTAKE; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC POLYMORPHISM; GENOTYPE; HEREDITY; HUMAN; LIPOPROTEIN METABOLISM; MAJOR CLINICAL STUDY; MALE; NUTRITION; OUTCOMES RESEARCH; PRIORITY JOURNAL; PROMOTER REGION; RISK ASSESSMENT;

ADULT; AGED; ALLELES; CARDIOVASCULAR DISEASES; CHOLESTEROL, HDL; COHORT STUDIES; DEMOGRAPHY; DIETARY FATS; ENERGY METABOLISM; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LIPASE; LIVER; MALE; MIDDLE AGED; POINT MUTATION; POLYMORPHISM, GENETIC; PROMOTER REGIONS (GENETICS); REGRESSION ANALYSIS; RISK;

EID: 0037195149     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000036597.52291.C9     Document Type: Article

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