-
1
-
-
0033694754
-
The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase
-
Atwal J. K., Massie B., Miller F. D. Kaplan D. R. (2000) The TrkB-Shc site signals neuronal survival and local axon growth via MEK and P13-kinase. Neuron 27, 265 277.
-
(2000)
Neuron
, vol.27
, pp. 265-277
-
-
Atwal, J.K.1
Massie, B.2
Miller, F.D.3
Kaplan, D.R.4
-
2
-
-
0035150732
-
Overexpression of Akt inhibits NGF-induced growth arrest and neuronal differentiation of PC12 cells
-
Bang O. S., Park E. K., Yang S. I., Lee S. R., Franke T. F. Kang S. S. (2001) Overexpression of Akt inhibits NGF-induced growth arrest and neuronal differentiation of PC12 cells. J. Cell Sci. 114, 81 88.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 81-88
-
-
Bang, O.S.1
Park, E.K.2
Yang, S.I.3
Lee, S.R.4
Franke, T.F.5
Kang, S.S.6
-
3
-
-
0342680014
-
Cranial MRI in the Nijmegen breakage syndrome
-
Bekiesinska-Figatowska M., Chrzanowska K. H., Sikorska J., Walecki J., Krajewska-Walasek M., Jozwiak S. Kleijer W. J. (2000) Cranial MRI in the Nijmegen breakage syndrome. Neuroradiology 42, 43 47.
-
(2000)
Neuroradiology
, vol.42
, pp. 43-47
-
-
Bekiesinska-Figatowska, M.1
Chrzanowska, K.H.2
Sikorska, J.3
Walecki, J.4
Krajewska-Walasek, M.5
Jozwiak, S.6
Kleijer, W.J.7
-
4
-
-
3042558276
-
Glycogen synthase kinase 3: A drug target for CNS therapies
-
Bhat R. V., Budd Haeberlein S. L. Avila J. (2004) Glycogen synthase kinase 3: a drug target for CNS therapies. J. Neurochem. 89, 1313 1317.
-
(2004)
J. Neurochem.
, vol.89
, pp. 1313-1317
-
-
Bhat, R.V.1
Budd Haeberlein, S.L.2
Avila, J.3
-
5
-
-
0035369623
-
Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway
-
Brunet A., Datta S. R. Greenberg M. E. (2001) Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway. Curr. Opin. Neurobiol. 11, 297 305.
-
(2001)
Curr. Opin. Neurobiol.
, vol.11
, pp. 297-305
-
-
Brunet, A.1
Datta, S.R.2
Greenberg, M.E.3
-
6
-
-
0026659868
-
Phosphatidylinositol 3-kinase is activated by nerve growth factor and epidermal growth factor in PC12 cells
-
Carter A. N. Downes C. P. (1992) Phosphatidylinositol 3-kinase is activated by nerve growth factor and epidermal growth factor in PC12 cells. J. Biol. Chem. 267, 14 563 14 567.
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 14563-14567
-
-
Carter, A.N.1
Downes, C.P.2
-
7
-
-
25444455323
-
Overexpression of NBS1 contributes to transformation through the activation of phosphatidylinositol 3-kinase/Akt
-
Chen Y. C., Su Y. N., Chou P. C., Chiang W. C., Chang M. C., Wang L. S., Teng S. C. Wu K. J. (2005) Overexpression of NBS1 contributes to transformation through the activation of phosphatidylinositol 3-kinase/Akt. J. Biol. Chem. 280, 32 505 32 511.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 32505-32511
-
-
Chen, Y.C.1
Su, Y.N.2
Chou, P.C.3
Chiang, W.C.4
Chang, M.C.5
Wang, L.S.6
Teng, S.C.7
Wu, K.J.8
-
8
-
-
0037805645
-
C-Myc directly regulates the transcription of the NBS1 gene involved in DNA double-strand break repair
-
Chiang Y. C., Teng S. C., Su Y. N., Hsieh F. J. Wu K. J. (2003) c-Myc directly regulates the transcription of the NBS1 gene involved in DNA double-strand break repair. J. Biol. Chem. 278, 19 286 19 291.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 19286-19291
-
-
Chiang, Y.C.1
Teng, S.C.2
Su, Y.N.3
Hsieh, F.J.4
Wu, K.J.5
-
9
-
-
20444394386
-
Inhibition of GSK3beta is a common event in neuroprotection by different survival factors
-
Chin P. C., Majdzadeh N. D'Mello S. R. (2005) Inhibition of GSK3beta is a common event in neuroprotection by different survival factors. Mol. Brain Res. 137, 193 201.
-
(2005)
Mol. Brain Res.
, vol.137
, pp. 193-201
-
-
Chin, P.C.1
Majdzadeh, N.2
D'Mello, S.R.3
-
10
-
-
0035227159
-
Atypical clinical picture of the Nijmegen breakage syndrome associated with developmental abnormalities of the brain
-
Chrzanowska K. H., Stumm M., Bekiesiska-Figatowska M., Varon R., Biaecka M., Gregorek H., Michakiewicz J., Krajewska-Walasek M., Jowiak S. Reis A. (2001) Atypical clinical picture of the Nijmegen breakage syndrome associated with developmental abnormalities of the brain. J. Med. Genet. 38, E3.
-
(2001)
J. Med. Genet.
, vol.38
-
-
Chrzanowska, K.H.1
Stumm, M.2
Bekiesiska-Figatowska, M.3
Varon, R.4
Biaecka, M.5
Gregorek, H.6
Michakiewicz, J.7
Krajewska-Walasek, M.8
Jowiak, S.9
Reis, A.10
-
11
-
-
0036580795
-
Corpus callosum hypoplasia and associated brain anomalies in Nijmegen breakage syndrome
-
Chrzanowska K. H., Bekiesinska-Figatowska M. Jozwiak S. (2002) Corpus callosum hypoplasia and associated brain anomalies in Nijmegen breakage syndrome. J. Med. Genet. 39, E25.
-
(2002)
J. Med. Genet.
, vol.39
-
-
Chrzanowska, K.H.1
Bekiesinska-Figatowska, M.2
Jozwiak, S.3
-
12
-
-
0032522924
-
Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons
-
Crowder R. J. Freeman R. S. (1998) Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons. J. Neurosci. 18, 2933 2943.
-
(1998)
J. Neurosci.
, vol.18
, pp. 2933-2943
-
-
Crowder, R.J.1
Freeman, R.S.2
-
13
-
-
0036276388
-
The Mre11 complex: At the crossroads of DNA repair and checkpoint signalling
-
D'Amours D. Jackson S. P. (2002) The Mre11 complex: at the crossroads of DNA repair and checkpoint signalling. Nat. Rev. Mol. Cell Biol. 3, 317 327.
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 317-327
-
-
D'Amours, D.1
Jackson, S.P.2
-
14
-
-
22144462810
-
Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models
-
Difilippantonio S., Celeste A., Fernandez-Capetillo O. et al. (2005) Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models. Nat. Cell Biol. 7, 675 685.
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 675-685
-
-
Difilippantonio, S.1
Celeste, A.2
Fernandez-Capetillo, O.3
-
15
-
-
3242892589
-
Nijmegen breakage syndrome: Clinical manifestation of defective response to DNA double-strand breaks
-
Digweed M. Sperling K. (2004) Nijmegen breakage syndrome: clinical manifestation of defective response to DNA double-strand breaks. DNA Repair 3, 1207 1217.
-
(2004)
DNA Repair
, vol.3
, pp. 1207-1217
-
-
Digweed, M.1
Sperling, K.2
-
16
-
-
0031053586
-
Regulation of neuronal survival by the serine - Threonine protein kinase Akt
-
Dudek H., Datta S. R., Franke T. F., Birnbaum M. J., Yao R., Cooper G. M., Segal R. A., Kaplan D. R. Greenberg M. E. (1997) Regulation of neuronal survival by the serine - threonine protein kinase Akt. Science 275, 661 665.
-
(1997)
Science
, vol.275
, pp. 661-665
-
-
Dudek, H.1
Datta, S.R.2
Franke, T.F.3
Birnbaum, M.J.4
Yao, R.5
Cooper, G.M.6
Segal, R.A.7
Kaplan, D.R.8
Greenberg, M.E.9
-
17
-
-
0031039024
-
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate
-
Franke T. F., Kaplan D. R., Cantley L. C. Toker A. (1997) Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4- bisphosphate. Science 275, 665 668.
-
(1997)
Science
, vol.275
, pp. 665-668
-
-
Franke, T.F.1
Kaplan, D.R.2
Cantley, L.C.3
Toker, A.4
-
18
-
-
18844394291
-
An essential function for NBS1 in the prevention of ataxia and cerebellar defects
-
Frappart P. O., Tong W. M., Demuth I., Radovanovic I., Herceg Z., Aguzzi A., Digweed M. Wang Z. Q. (2005) An essential function for NBS1 in the prevention of ataxia and cerebellar defects. Nat. Med. 11, 538 544.
-
(2005)
Nat. Med.
, vol.11
, pp. 538-544
-
-
Frappart, P.O.1
Tong, W.M.2
Demuth, I.3
Radovanovic, I.4
Herceg, Z.5
Aguzzi, A.6
Digweed, M.7
Wang, Z.Q.8
-
19
-
-
0030971576
-
Activation of mitogen-activated protein kinase and p70S6 kinase is not correlated with cerebellar granule cell survival
-
Gunn-Moore F. J., Williams A. G., Toms N. J. Tavare J. M. (1997) Activation of mitogen-activated protein kinase and p70S6 kinase is not correlated with cerebellar granule cell survival. Biochem. J. 324, 365 369.
-
(1997)
Biochem. J.
, vol.324
, pp. 365-369
-
-
Gunn-Moore, F.J.1
Williams, A.G.2
Toms, N.J.3
Tavare, J.M.4
-
20
-
-
0037147327
-
ERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neurons
-
Hetman M., Hsuan S. L., Habas A., Higgins M. J. Xia Z. (2002) ERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neurons. J. Biol. Chem. 277, 49 577 49 584.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 49577-49584
-
-
Hetman, M.1
Hsuan, S.L.2
Habas, A.3
Higgins, M.J.4
Xia, Z.5
-
21
-
-
0042566203
-
The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells
-
Higuchi M., Onishi K., Masuyama N. Gotoh Y. (2003) The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells. Genes Cells 8, 657 669.
-
(2003)
Genes Cells
, vol.8
, pp. 657-669
-
-
Higuchi, M.1
Onishi, K.2
Masuyama, N.3
Gotoh, Y.4
-
22
-
-
0030039995
-
Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase
-
Jackson T. R., Blader I. J., Hammonds-Odie L. P., Burga C. R., Cooke F., Hawkins P. T., Wolf A. G., Heldman K. A. Theibert A. B. (1996) Initiation and maintenance of NGF-stimulated neurite outgrowth requires activation of a phosphoinositide 3-kinase. J. Cell Sci. 109, 289 300.
-
(1996)
J. Cell Sci.
, vol.109
, pp. 289-300
-
-
Jackson, T.R.1
Blader, I.J.2
Hammonds-Odie, L.P.3
Burga, C.R.4
Cooke, F.5
Hawkins, P.T.6
Wolf, A.G.7
Heldman, K.A.8
Theibert, A.B.9
-
23
-
-
30544449810
-
Control of dendritic arborization by the phosphoinositide-3'-kinase-Akt- mammalian target of rapamycin pathway
-
Jaworski J., Spangler S., Seeburg D. P., Hoogenraad C. C. Sheng M. (2005) Control of dendritic arborization by the phosphoinositide-3'-kinase-Akt- mammalian target of rapamycin pathway. J. Neurosci. 25, 11 300 11 312.
-
(2005)
J. Neurosci.
, vol.25
, pp. 11300-11312
-
-
Jaworski, J.1
Spangler, S.2
Seeburg, D.P.3
Hoogenraad, C.C.4
Sheng, M.5
-
24
-
-
20144363322
-
NT3 inhibits FGF2-induced neural progenitor cell proliferation via the PI3K/GSK3 pathway
-
Jin L., Hu X. Feng L. (2005) NT3 inhibits FGF2-induced neural progenitor cell proliferation via the PI3K/GSK3 pathway. J. Neurochem. 93, 1251 1261.
-
(2005)
J. Neurochem.
, vol.93
, pp. 1251-1261
-
-
Jin, L.1
Hu, X.2
Feng, L.3
-
25
-
-
0041430783
-
The synergistic effects of NGF and IGF-1 on neurite growth in adult sensory neurons: Convergence on the PI 3-kinase signaling pathway
-
Jones D. M., Tucker B. A., Rahimtula M. Mearow K. M. (2003) The synergistic effects of NGF and IGF-1 on neurite growth in adult sensory neurons: convergence on the PI 3-kinase signaling pathway. J. Neurochem. 86, 1116 1128.
-
(2003)
J. Neurochem.
, vol.86
, pp. 1116-1128
-
-
Jones, D.M.1
Tucker, B.A.2
Rahimtula, M.3
Mearow, K.M.4
-
26
-
-
11844259424
-
Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression
-
Kang J., Ferguson D., Song H., Bassing C., Eckersdorff M., Alt F. W. Xu Y. (2005) Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression. Mol. Cell Biol. 25, 661 670.
-
(2005)
Mol. Cell Biol.
, vol.25
, pp. 661-670
-
-
Kang, J.1
Ferguson, D.2
Song, H.3
Bassing, C.4
Eckersdorff, M.5
Alt, F.W.6
Xu, Y.7
-
27
-
-
0034044227
-
Neurotrophin signal transduction in the nervous system
-
Kaplan D. R. Miller F. D. (2000) Neurotrophin signal transduction in the nervous system. Curr. Opin. Neurobiol. 10, 381 391.
-
(2000)
Curr. Opin. Neurobiol.
, vol.10
, pp. 381-391
-
-
Kaplan, D.R.1
Miller, F.D.2
-
28
-
-
14544300519
-
A positive role of the PI3-K/Akt signaling pathway in PC12 cell differentiation
-
Kim Y., Seger R., Suresh Babu C. V., Hwang S. Y. Yoo Y. S. (2004) A positive role of the PI3-K/Akt signaling pathway in PC12 cell differentiation. Mol. Cells 18, 353 359.
-
(2004)
Mol. Cells
, vol.18
, pp. 353-359
-
-
Kim, Y.1
Seger, R.2
Suresh Babu, C.V.3
Hwang, S.Y.4
Yoo, Y.S.5
-
29
-
-
0028242353
-
Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase
-
Kimura K., Hattori S., Kabuyama Y., Shizawa Y., Takayanagi J., Nakamura S., Toki S., Matsuda Y., Onodera K. Fukui Y. (1994) Neurite outgrowth of PC12 cells is suppressed by wortmannin, a specific inhibitor of phosphatidylinositol 3-kinase. J. Biol. Chem. 269, 18 961 18 967.
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 18961-18967
-
-
Kimura, K.1
Hattori, S.2
Kabuyama, Y.3
Shizawa, Y.4
Takayanagi, J.5
Nakamura, S.6
Toki, S.7
Matsuda, Y.8
Onodera, K.9
Fukui, Y.10
-
30
-
-
0031956449
-
Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway
-
Kita Y., Kimura K. D., Kobayashi M. et al. (1998) Microinjection of activated phosphatidylinositol-3 kinase induces process outgrowth in rat PC12 cells through the Rac-JNK signal transduction pathway. J. Cell Sci. 111, 907 915.
-
(1998)
J. Cell Sci.
, vol.111
, pp. 907-915
-
-
Kita, Y.1
Kimura, K.D.2
Kobayashi, M.3
-
31
-
-
0034011447
-
Clinical presentation and mutation identification in the NBS1 gene in a boy with Nijmegen breakage syndrome
-
Kleier S., Herrmann M., Wittwer B., Varon R., Reis A. Horst J. (2000) Clinical presentation and mutation identification in the NBS1 gene in a boy with Nijmegen breakage syndrome. Clin. Genet. 57, 384 387.
-
(2000)
Clin. Genet.
, vol.57
, pp. 384-387
-
-
Kleier, S.1
Herrmann, M.2
Wittwer, B.3
Varon, R.4
Reis, A.5
Horst, J.6
-
32
-
-
0030917921
-
Expression of a constitutively active phosphatidylinositol 3-kinase induces process formation in rat PC12 cells. Use of Cre/loxP recombination system
-
Kobayashi M., Nagata S., Kita Y. et al. (1997) Expression of a constitutively active phosphatidylinositol 3-kinase induces process formation in rat PC12 cells. Use of Cre/loxP recombination system. J. Biol. Chem. 272, 16 089 16 092.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16089-16092
-
-
Kobayashi, M.1
Nagata, S.2
Kita, Y.3
-
33
-
-
0033008552
-
Immortalization and characterization of Nijmegen Breakage syndrome fibroblasts
-
Kraakman-van der Zwet M., Overkamp W. J., Friedl A. A., Klein B., Verhaegh G. W., Jaspers N. G., Midro A. T., Eckardt-Schupp F., Lohman P. H. Zdzienicka M. Z. (1999) Immortalization and characterization of Nijmegen Breakage syndrome fibroblasts. Mutat. Res. 434, 17 27.
-
(1999)
Mutat. Res.
, vol.434
, pp. 17-27
-
-
Kraakman-Van Der Zwet, M.1
Overkamp, W.J.2
Friedl, A.A.3
Klein, B.4
Verhaegh, G.W.5
Jaspers, N.G.6
Midro, A.T.7
Eckardt-Schupp, F.8
Lohman, P.H.9
Zdzienicka, M.Z.10
-
34
-
-
0033695838
-
Spatially and functionally distinct roles of the PI3-K effector pathway during NGF signaling in sympathetic neurons
-
Kuruvilla R., Ye H. Ginty D. D. (2000) Spatially and functionally distinct roles of the PI3-K effector pathway during NGF signaling in sympathetic neurons. Neuron 27, 499 512.
-
(2000)
Neuron
, vol.27
, pp. 499-512
-
-
Kuruvilla, R.1
Ye, H.2
Ginty, D.D.3
-
35
-
-
0242268407
-
MTor is required for hypertrophy of Pten-deficient neuronal soma in vivo
-
Kwon C. H., Zhu X., Zhang J. Baker S. J. (2003) mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo. Proc. Natl. Acad. Sci. U.S.A. 100, 12 923 12 928.
-
(2003)
Proc. Natl. Acad. Sci. U.S.A.
, vol.100
, pp. 12923-12928
-
-
Kwon, C.H.1
Zhu, X.2
Zhang, J.3
Baker, S.J.4
-
36
-
-
0141849405
-
Nijmegen breakage syndrome: A neuropathological study
-
Lammens M., Hiel J. A., Gabreels F. J., van Engelen B. G., van den Heuvel L. P. Weemaes C. M. (2003) Nijmegen breakage syndrome: a neuropathological study. Neuropediatrics 34, 189 193.
-
(2003)
Neuropediatrics
, vol.34
, pp. 189-193
-
-
Lammens, M.1
Hiel, J.A.2
Gabreels, F.J.3
Van Engelen, B.G.4
Van Den Heuvel, L.P.5
Weemaes, C.M.6
-
37
-
-
0034845958
-
PKB/Akt: A key mediator of cell proliferation, survival and insulin responses?
-
Lawlor M. A. Alessi D. R. (2001) PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? J. Cell Sci. 114, 2903 2910.
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2903-2910
-
-
Lawlor, M.A.1
Alessi, D.R.2
-
38
-
-
0037025058
-
The mechanisms of neuronal death produced by mitochondrial toxin 3-nitropropionic acid: The roles of N-methyl-d-aspartate glutamate receptors and mitochondrial calcium overload
-
Lee W. T., Yin H. S. Shen Y. Z. (2002) The mechanisms of neuronal death produced by mitochondrial toxin 3-nitropropionic acid: the roles of N-methyl-d-aspartate glutamate receptors and mitochondrial calcium overload. Neuroscience 112, 707 716.
-
(2002)
Neuroscience
, vol.112
, pp. 707-716
-
-
Lee, W.T.1
Yin, H.S.2
Shen, Y.Z.3
-
39
-
-
0035109016
-
A novel mutation and novel features in Nijmegen breakage syndrome
-
Maraschio P., Danesino C., Antoccia A., Ricordy R., Tanzarella C., Varon R., Reis A., Besana D., Guala A. Tiepolo L. (2001) A novel mutation and novel features in Nijmegen breakage syndrome. J. Med. Genet. 38, 113 117.
-
(2001)
J. Med. Genet.
, vol.38
, pp. 113-117
-
-
Maraschio, P.1
Danesino, C.2
Antoccia, A.3
Ricordy, R.4
Tanzarella, C.5
Varon, R.6
Reis, A.7
Besana, D.8
Guala, A.9
Tiepolo, L.10
-
40
-
-
0037014483
-
Raf and akt mediate distinct aspects of sensory axon growth
-
Markus A., Zhong J. Snider W. D. (2002) Raf and akt mediate distinct aspects of sensory axon growth. Neuron 35, 65 76.
-
(2002)
Neuron
, vol.35
, pp. 65-76
-
-
Markus, A.1
Zhong, J.2
Snider, W.D.3
-
41
-
-
0035068565
-
An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele
-
Maser R. S., Zinkel R. Petrini J. H. (2001) An alternative mode of translation permits production of a variant NBS1 protein from the common Nijmegen breakage syndrome allele. Nat. Genet. 27, 417 421.
-
(2001)
Nat. Genet.
, vol.27
, pp. 417-421
-
-
Maser, R.S.1
Zinkel, R.2
Petrini, J.H.3
-
43
-
-
0034655803
-
Akt/protein kinase B prevents injury-induced motoneuron death and accelerates axonal regeneration
-
Namikawa K., Honma M., Abe K., Takeda M., Mansur K., Obata T., Miwa A., Okado H. Kiyama H. (2000) Akt/protein kinase B prevents injury-induced motoneuron death and accelerates axonal regeneration. J. Neurosci. 20, 2875 2886.
-
(2000)
J. Neurosci.
, vol.20
, pp. 2875-2886
-
-
Namikawa, K.1
Honma, M.2
Abe, K.3
Takeda, M.4
Mansur, K.5
Obata, T.6
Miwa, A.7
Okado, H.8
Kiyama, H.9
-
44
-
-
0034020464
-
The Mre11 complex and ATM: Collaborating to navigate S phase
-
Petrini J. H. (2000) The Mre11 complex and ATM: collaborating to navigate S phase. Curr. Opin. Cell Biol. 12, 293 296.
-
(2000)
Curr. Opin. Cell Biol.
, vol.12
, pp. 293-296
-
-
Petrini, J.H.1
-
45
-
-
0030694175
-
Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons
-
Philpott K. L., McCarthy M. J., Klippel A. Rubin L. L. (1997) Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons. J. Cell Biol. 139, 809 815.
-
(1997)
J. Cell Biol.
, vol.139
, pp. 809-815
-
-
Philpott, K.L.1
McCarthy, M.J.2
Klippel, A.3
Rubin, L.L.4
-
46
-
-
16244420094
-
Akt-dependent cell size regulation by the adhesion molecule on glia occurs independently of phosphatidylinositol 3-kinase and Rheb signaling
-
Scheidenhelm D. K., Cresswell J., Haipek C. A., Fleming T. P., Mercer R. W. Gutmann D. H. (2005) Akt-dependent cell size regulation by the adhesion molecule on glia occurs independently of phosphatidylinositol 3-kinase and Rheb signaling. Mol. Cell Biol. 25, 3151 3162.
-
(2005)
Mol. Cell Biol.
, vol.25
, pp. 3151-3162
-
-
Scheidenhelm, D.K.1
Cresswell, J.2
Haipek, C.A.3
Fleming, T.P.4
Mercer, R.W.5
Gutmann, D.H.6
-
47
-
-
33645125102
-
Nijmegen breakage syndrome (NBS) with neurological abnormalities and without chromosomal instability
-
Seemanová E., Sperling K., Neitzel H., Varon R., Hadac J., Butova O., Schröck E., Seeman P. Digweed M. (2006) Nijmegen breakage syndrome (NBS) with neurological abnormalities and without chromosomal instability. J. Med. Genet. 43, 218 224.
-
(2006)
J. Med. Genet.
, vol.43
, pp. 218-224
-
-
Seemanová, E.1
Sperling, K.2
Neitzel, H.3
Varon, R.4
Hadac, J.5
Butova, O.6
Schröck, E.7
Seeman, P.8
Digweed, M.9
-
48
-
-
4744355621
-
Akt-1 expression level regulates CNS precursors
-
Sinor A. D. Lillien L. (2004) Akt-1 expression level regulates CNS precursors. J. Neurosci. 24, 8531 8541.
-
(2004)
J. Neurosci.
, vol.24
, pp. 8531-8541
-
-
Sinor, A.D.1
Lillien, L.2
-
49
-
-
0032076190
-
Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome
-
Varon R., Vissinga C., Platzer M. et al. (1998) Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome. Cell 93, 467 476.
-
(1998)
Cell
, vol.93
, pp. 467-476
-
-
Varon, R.1
Vissinga, C.2
Platzer, M.3
-
50
-
-
0035328489
-
Mutations in the Nijmegen breakage syndrome gene (NBS1) in childhood acute lymphoblastic leukemia (ALL)
-
Varon R., Reis A., Henze G., von Einsiedel H. G., Sperling K. Seeger K. (2001) Mutations in the Nijmegen breakage syndrome gene (NBS1) in childhood acute lymphoblastic leukemia (ALL). Cancer Res. 61, 3570 3572.
-
(2001)
Cancer Res.
, vol.61
, pp. 3570-3572
-
-
Varon, R.1
Reis, A.2
Henze, G.3
Von Einsiedel, H.G.4
Sperling, K.5
Seeger, K.6
-
51
-
-
33144484246
-
Mild Nijmegen breakage syndrome (NBS) phenotype due to alternative splicing
-
Varon R., Dutrannoy V., Weikert G. et al. (2006) Mild Nijmegen breakage syndrome (NBS) phenotype due to alternative splicing. Hum. Mol. Genet. 15, 679 689.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 679-689
-
-
Varon, R.1
Dutrannoy, V.2
Weikert, G.3
-
52
-
-
0036632368
-
The phosphatidylinositol 3-kinase AKT pathway in human cancer
-
Vivanco I. Sawyers C. L. (2002) The phosphatidylinositol 3-kinase AKT pathway in human cancer. Nat. Rev. Cancer 2, 489 501.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
53
-
-
4444221268
-
Essential role for phospholipase D2 activation downstream of ERK MAP kinase in nerve growth factor-stimulated neurite outgrowth from PC12 cells
-
Watanabe H., Yokozeki T., Yamazaki M., Miyazaki H., Sasaki T., Maehama T., Itoh K., Frohman M. A. Kanaho Y. (2004) Essential role for phospholipase D2 activation downstream of ERK MAP kinase in nerve growth factor-stimulated neurite outgrowth from PC12 cells. J. Biol. Chem. 279, 37 870 37 877.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 37870-37877
-
-
Watanabe, H.1
Yokozeki, T.2
Yamazaki, M.3
Miyazaki, H.4
Sasaki, T.5
Maehama, T.6
Itoh, K.7
Frohman, M.A.8
Kanaho, Y.9
-
54
-
-
0033852325
-
Expression pattern of the Nijmegen breakage syndrome gene, Nbs1, during murine development
-
Wilda M., Demuth I., Concannon P., Sperling K. Hameister H. (2000) Expression pattern of the Nijmegen breakage syndrome gene, Nbs1, during murine development. Hum. Mol. Genet. 9, 1739 1744.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 1739-1744
-
-
Wilda, M.1
Demuth, I.2
Concannon, P.3
Sperling, K.4
Hameister, H.5
-
55
-
-
0033120296
-
Evidence for and against a pivotal role of PI 3-kinase in a neuronal cell survival pathway
-
Williams E. J. Doherty P. (1999) Evidence for and against a pivotal role of PI 3-kinase in a neuronal cell survival pathway. Mol. Cell Neurosci. 13, 272 280.
-
(1999)
Mol. Cell Neurosci.
, vol.13
, pp. 272-280
-
-
Williams, E.J.1
Doherty, P.2
-
56
-
-
0037117410
-
A murine model of Nijmegen breakage syndrome
-
Williams B. R., Mirzoeva O. K., Morgan W. F., Lin J., Dunnick W. Petrini J. H. (2002) A murine model of Nijmegen breakage syndrome. Curr. Biol. 12, 648 653.
-
(2002)
Curr. Biol.
, vol.12
, pp. 648-653
-
-
Williams, B.R.1
Mirzoeva, O.K.2
Morgan, W.F.3
Lin, J.4
Dunnick, W.5
Petrini, J.H.6
-
57
-
-
0034713466
-
ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response
-
Wu X., Ranganathan V., Weisman D. S. et al. (2000) ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response. Nature 405, 477 482.
-
(2000)
Nature
, vol.405
, pp. 477-482
-
-
Wu, X.1
Ranganathan, V.2
Weisman, D.S.3
-
58
-
-
31544465282
-
Increased NBS1 expression is a prognostic marker of aggressive head and neck cancer and overexpression of NBS1 contributes to transformation
-
Yang M. H., Chiang W. C., Chou T. Y., Chang S. Y., Chen P. M., Teng S. C. Wu K. J. (2006) Increased NBS1 expression is a prognostic marker of aggressive head and neck cancer and overexpression of NBS1 contributes to transformation. Clin. Cancer Res. 12, 507 515.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 507-515
-
-
Yang, M.H.1
Chiang, W.C.2
Chou, T.Y.3
Chang, S.Y.4
Chen, P.M.5
Teng, S.C.6
Wu, K.J.7
-
59
-
-
0034713393
-
Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products
-
Zhao S., Weng Y. C., Yuan S. S. et al. (2000) Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products. Nature 405, 473 477.
-
(2000)
Nature
, vol.405
, pp. 473-477
-
-
Zhao, S.1
Weng, Y.C.2
Yuan, S.S.3
-
60
-
-
27144446140
-
Akt contributes to neuroprotection by hypothermia against cerebral ischemia in rats
-
Zhao H., Shimohata T., Wang J. Q., Sun G., Schaal D. W., Sapolsky R. M. Steinberg G. K. (2005) Akt contributes to neuroprotection by hypothermia against cerebral ischemia in rats. J. Neurosci. 25, 9794 806.
-
(2005)
J. Neurosci.
, vol.25
, pp. 9794-806
-
-
Zhao, H.1
Shimohata, T.2
Wang, J.Q.3
Sun, G.4
Schaal, D.W.5
Sapolsky, R.M.6
Steinberg, G.K.7
-
61
-
-
0035936554
-
Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice
-
Zhu J., Petersen S., Tessarollo L. Nussenzweig A. (2001) Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice. Curr. Biol. 11, 105 109.
-
(2001)
Curr. Biol.
, vol.11
, pp. 105-109
-
-
Zhu, J.1
Petersen, S.2
Tessarollo, L.3
Nussenzweig, A.4
|