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Volumn 9, Issue 3, 2007, Pages 487-500

Solid-phase preparation of a pilot library derived from the 2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-amine Scaffold

Author keywords

[No Author keywords available]

Indexed keywords

BENZAZEPINE DERIVATIVE;

EID: 34249929781     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc060164x     Document Type: Article
Times cited : (31)

References (77)
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    • Microwave irradiation (120°C, 15 min) could be alternatively used to remove the Ts group with a similar result.
    • Microwave irradiation (120°C, 15 min) could be alternatively used to remove the Ts group with a similar result.
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    • Three alternative protecting groups orthogonal to acid-labile linkers were evaluated but found either not compatible with our synthetic scheme (Fmoc) or not convenient/amenable for preparation of a large library Alloc, oNS
    • Three alternative protecting groups orthogonal to acid-labile linkers were evaluated but found either not compatible with our synthetic scheme (Fmoc) or not convenient/amenable for preparation of a large library (Alloc, oNS).
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    • 2 in DCM at reflux for 2 h.
    • 2 in DCM at reflux for 2 h.
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    • For a review on Pd-catalyzed reaction performed on a solid-supported substrate see
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    • Use of PEPPSI Catalyst in Buchwald-Hartwig Amination Reactions
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    • Dubovyk, I.1    Avola, S.2    Kantchev, E.A.B.3    O'Brien, C.4    Organ, M.G.5    Valente, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.