A method for removal of N-BOC protecting groups from substrates on TFA- sensitive resins

Tetrahedron Letters

Volumn 39, Issue 41, 1998, Pages 7439-7442

  Zhang, Alex J ^a   Russell, David H ^a   Zhu, Jieping ^b   Burgess, Kevin ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b CNRS   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALKYL GROUP; N TERT BUTYLOXYCARBONYL DERIVATIVE; UNCLASSIFIED DRUG; VANCOMYCIN DERIVATIVE;

ARTICLE; CHEMICAL REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; STRUCTURE ANALYSIS;

EID: 0032497661     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(98)01631-1     Document Type: Article

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11. 2O (30 mL). The purities of the peptides were checked by analytical RP-HPLC (Vydac C18 column, 4.6 mm × 25 cm, 5 μm), the crude peptides were further purified by preparative RP-HPLC (Vydac C18 column, 22 mm × 25 cm, 10 μm).