Amyloid β-protein induced electrophysiological changes are dependent on aggregation state: N-methyl-D-aspartate (NMDA) versus non-NMDA receptor/channel activation

Neuroscience Letters

Volumn 366, Issue 3, 2004, Pages 320-325

  Ye, Chianping ^a   Walsh, Dominic M ^b,c   Selkoe, Dennis J ^b   Hartley, Dean M ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b Brigham and Women's Hospital Center for Neurologic Diseases   (United States)

^c UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Aggregation; Alzheimer; Amyloid protein; Electrophysiology; Fibrillogenesis; Glutamate; Neurodegeneration; Protofibrils

Indexed keywords

AMYLOID BETA PROTEIN; MAGNESIUM ION; N METHYL DEXTRO ASPARTIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; CHANNEL GATING; COMPARATIVE STUDY; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FIBER; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPTIC TRANSMISSION;

AMYLOID BETA-PROTEIN; ANIMALS; CELLS, CULTURED; DRUG INTERACTIONS; EMBRYO; EXCITATORY AMINO ACID ANTAGONISTS; IMMUNOHISTOCHEMISTRY; MEMBRANE POTENTIALS; MICROTUBULE-ASSOCIATED PROTEINS; NEOCORTEX; NEURONS; PATCH-CLAMP TECHNIQUES; PROTEIN CONFORMATION; QUINOXALINES; RATS; RECEPTORS, N-METHYL-D-ASPARTATE; VALINE;

EID: 3543060658     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2004.05.060     Document Type: Article

References (37)

1. Chen Q.S., Kagan B.L., Hirakura Y., Xie C.W. Impairment of hippocampal long-term potentiation by Alzheimer amyloid beta-peptides. J. Neurosci. Res. 60:2000;65-72
2. Chen Q.S., Wei W.Z., Shimahara T., Xie C.W. Alzheimer amyloid beta-peptide inhibits the late phase of long-term potentiation through calcineurin-dependent mechanisms in the hippocampal dentate gyrus. Neurobiol. Learn. Memory. 77:2002;354-371
3. Cullen W.K., Suh Y.H., Anwyl R., Rowan M.J. Block of LTP in rat hippocampus in vivo by beta-amyloid precursor protein fragments. Neuroreport. 8:1997;3213-3217
4. Cullen W.K., Wu J., Anwyl R., Rowan M.J. β-Amyloid produces a delayed NMDA receptor-dependent reduction in synaptic transmission in rat hippocampus. Neuroreport. 8:1996;87-92
5. Davies J., Watkins J.C. Actions of D and L forms of 2-amino-5- phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord. Brain Res. 235:1982;378-386
6. Freir D.B., Holscher C., Herron C.E. Blockade of long-term potentiation by beta-amyloid peptides in the CA1 region of the rat hippocampus in vivo. J. Neurophysiol. 85:2001;708-713
7. Halverson K., Fraser P.E., Kirschner D.A., Lansbury P.T.J. Molecular determinants of amyloid deposition in Alzheimer's disease: conformational studies of synthetic beta-protein fragments. Biochemistry. 29:1990;2639-2644
8. Harper J.D., Wong S.S., Lieber C.M., Lansbury P.T. Observation of metastable Abeta amyloid protofibrils by atomic force microscopy. Chem. Biol. 4:1997;119-125
9. Harper J.D., Wong S.S., Lieber C.M., Lansbury P.T. Assembly of Abeta amyloid protofibrils: an in vitro model for a possible early event in Alzheimer's disease. Biochemistry. 38:1999;8972-8980
10. Hartley D., Walsh D.M., Ye C.P., Diehl T., Vasquez S., Vassilev P.M., Teplow D.B., Selkoe D.J. Protofibrillar intermediates of amyloid β-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons. J. Neurosci. 19:1999;8876-8884
11. Hickmott P.W., Constantine-Paton M. Experimental down-regulation of the NMDA channel associated with synapse pruning. J. Neurophysiol. 78:1997;1096-1107
12. Hsia A.Y., Masliah E., McConlogue L., Yu G.Q., Tatsuno G., Hu K., Kholodenko D., Malenka R.C., Nicoll R.A., Mucke L. Plaque-independent disruption of neural circuits in Alzheimer's disease mouse models. Proc. Natl. Acad. Sci. U.S.A. 96:1999;3228-3233
13. Itoh A., Akaike T., Sokabe M., Nitta A., Iida R., Olariu A., Yamada K., Nabeshima T. Impairments of long-term potentiation in hippocampal slices of beta-amyloid-infused rats. Eur. J. Pharmacol. 382:1999;167-175
14. Kirkitadze M.D., Bitan G., Teplow D.B. Paradigm shifts in Alzheimer's disease and other neurodegenerative disorders: the emerging role of oligomeric assemblies. J. Neurosci. Res. 69:2002;567-577
15. Kirschner D.A., Abraham C., Selkoe D.J. X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer's disease indicates cross-beta conformation. Proc. Natl. Acad. Sci. U.S.A. 83:1986;503-507
16. Kirschner D.A., Inouye H., Duffy L.K., Sinclair A., Lind M., Selkoe D.J. Synthetic peptide homologous to ß protein from Alzheimer disease forms amyloid-like fibrils in vitro. Proc. Natl. Acad. Sci. U.S.A. 84:1987;6953-6957
17. 1-42 are potent central nervous system neurotoxins. Proc. Natl. Acad. Sci. U.S.A. 95:1998;6448-6453
18. Merz P.A., Wisniewski H.M., Somerville R.A., Bobin S.A., Masters C.L., Iqbal K. Ultrastructural morphology of amyloid fibrils from neuritic and amyloid plaques. Acta Neuropathol. 60:1983;113-124
19. Oster Y., Schramm M. Down-regulation of NMDA receptor activity by NMDA. Neurosci. Lett. 163:1993;85-88
20. Raymond C.R., Ireland D.R., Abraham W.C. NMDA receptor regulation by amyloid-β does not account for its inhibition of LTP in rat hippocampus. Brain Res. 968:2003;263-272
21. Resink A., Villa M., Boer G.J., Mohler H., Balazs R. Agonist-induced down-regulation of NMDA receptors in cerebellar granule cells in culture. Eur. J. Neurosci. 7:1995;1700-1706
22. Robinson H.P., Kawahara M., Jimbo Y., Torimitsu K., Kuroda Y., Kawana A. Periodic synchronized bursting and intracellular calcium transients. J. Neurophysiol. 70:1993;1606-1616
23. Selkoe D.J. Alzheimer's disease is a synaptic failure. Science. 298:2002;789-791
24. Serpell L.C., Smith J.M. Direct visualisation of the beta-sheet structure of synthetic Alzheimer's amyloid. J. Mol. Biol. 299:2000;225-231
25. Sheardown M.J., Nielsen E.O., Hansen A.J., Jacobsen P., Honore T. 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia. Science. 247:1990;571-574
26. Stone T.W. The relative potencies of (-)-2-amino-5-phosphonovalerate and (-)-2-amino-7-phosphonoheptanoate as antagonists of N-methylaspartate and quinolinic acids and repetitive spikes in rat hippocampal slices. Brain Res. 381:1986;195-198
27. Teplow D.B. Structural and kinetic features of amyloid beta-protein fibrillogenesis. Amyloid. 5:1998;121-142
28. Walsh D.M., Hartley D.M., Kusumoto Y., Fezoui Y., Condron M.M., Lomakin A., Benedek G.B., Selkoe D.J., Teplow D.B. Amyloid beta-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates. J. Biol. Chem. 274:1999;25945-25952
29. Walsh D.M., Hartley D.M., Selkoe D.J. The many faces of Aβ: structures and activity. Curr. Med. Chem. 3:2003;277-291
30. Walsh D.M., Klyubin I., Fadeeva J.V., Cullen W.K., Anwyl R., Wolfe M.S., Rowan M.J., Selkoe D.J. Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo. Nature. 416:2002;535-539
31. Walsh D.M., Lomakin A., Benedek G.B., Maggio J.E., Condron M.M., Teplow D.B. Amyloid β-protein fibrillogenesis: detection of a protofibrillar intermediate. J. Biol. Chem. 272:1997;22364-22374
32. Wang H.W., Pasternak J.F., Kuo H., Ristic H., Lambert M.P., Chromy B., Viola K.L., Klein W.L., Stine W.B., Krafft G.A., Trommer B.L. Soluble oligomers of beta amyloid (1-42) inhibit long-term potentiation but not long-term depression in rat dentate gyrus. Brain Res. 924:2002;133-140
33. Wang Q., Walsh D.M., Rowan M.J., Selkoe D.J., Anwyl R. Aβ-induced block of LTP is mediated via activation of the receptors mGlu5 and the kinases JNK, Cdk5 and p38 MAP kinase. J. Neurosci. 24:2004;3370-3378
34. 2+ oscillations in cortical neurons. Brain Res. 767:1997;239-249
35. Wu J., Anwyl R., Rowan M.J. beta-Amyloid selectively augments NMDA receptor-mediated synaptic transmission in rat hippocampus. Neuroreport. 6:1995;2409-2413
36. Wu J., Anwyl R., Rowan M.J. Beta-amyloid-(1-40) increases long-term potentiation in rat hippocampus in vitro. Eur. J. Pharmacol. 284:1995;R1-R3
37. Ye C.P., Selkoe D.J., Hartley D.M. Protofibrils of amyloid beta-protein inhibit specific K+ currents in neocortical cultures. Neurobiol. Dis. 13:2003;177-190