Kinetics of amyloid β-protein degradation determined by novel fluorescence- and fluorescence polarization-based assays

Journal of Biological Chemistry

Volumn 278, Issue 39, 2003, Pages 37314-37320

  Leissring, Malcolm A ^a   Lu, Alice ^a   Condron, Margaret M ^a   Teplow, David B ^a   Stein, Ross L ^b   Farris, Wesley ^a   Selkoe, Dennis J ^a,c  

^a Brigham and Women's Hospital Center for Neurologic Diseases   (United States)

^b The Harvard Center for Neurodegeneration & Repair   (United States)

^c HARVARD INSTITUTES OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; DISEASE CONTROL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NEUROLOGY;

PROTEIN DEGRADATION;

ENZYMES;

AMYLOID BETA PROTEIN; ENZYME ACTIVATOR; FLUORESCEIN DERIVATIVE; INSULINASE; MEMBRANE METALLOENDOPEPTIDASE; PEPTIDE; PLASMIN; PROTEINASE; PROTEINASE INHIBITOR;

ALZHEIMER DISEASE; ARTICLE; ASSAY; BRAIN; DERIVATIZATION; ENZYME SUBSTRATE; FLUORESCENCE; FLUORESCENCE POLARIZATION; HYDROLYSIS; KINETICS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN DEGRADATION; QUANTITATIVE ASSAY;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; FLUORESCENCE; FLUORESCENCE POLARIZATION; INSULYSIN; KINETICS; MOLECULAR SEQUENCE DATA; NEPRILYSIN; PLASMIN;

EID: 0141621234     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M305627200     Document Type: Article

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