Rational design of novel, potent small molecule pan-selectin antagonists

Journal of Medicinal Chemistry

Volumn 50, Issue 6, 2007, Pages 1101-1115

  Kranich, Remo ^a   Busemann, Anke S ^a   Bock, Daniel ^a   Schroeter Maas, Sabine ^a   Beyer, Diana ^a   Heinemann, Bo ^a   Meyer, Michael ^a   Schierhorn, Katrin ^a   Zahlten, Rainer ^a   Wolff, Gerhard ^a   Aydt, Ewald M ^a  

^a Revotar Biopharmaceuticals AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; BENZENE DERIVATIVE; BIMOSIAMOSE; BIMOSIAMOSE DERIVATIVE; CELL ADHESION MOLECULE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; L SELECTIN; PADGEM PROTEIN; SELECTIN ANTAGONIST; TRIHYDROXYBENZENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CELL STRAIN HL 60; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BINDING; DRUG DESIGN; DRUG STRUCTURE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIGAND BINDING; MOLECULAR INTERACTION; MOLECULE;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BINDING, COMPETITIVE; CELL ADHESION; DRUG DESIGN; E-SELECTIN; HEXANES; HL-60 CELLS; HUMANS; L-SELECTIN; LIGANDS; MANNOSE; MODELS, MOLECULAR; P-SELECTIN; PHENOLS; PROTEIN BINDING; SELECTINS;

EID: 33947682115     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm060536g     Document Type: Article

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