Studies on selectin blockers. 4. Structure-function relationships of sulfated sialyl Lewis X hexasaccharide ceramides toward E-, P-, and L- selectin binding

Journal of Medicinal Chemistry

Volumn 40, Issue 4, 1997, Pages 455-462

  Yoshino, Kohichiro ^a   Ohmoto, Hiroshi ^a   Kondo, Noriko ^a   Tsujishita, Hideki ^a   Hiramatsu, Yasuyuki ^a   Inoue, Yoshimasa ^a   Kondo, Hirosato ^a   Ishida, Hideharu ^b   Kiso, Makoto ^b   Hasegawa, Akira ^b  

^a KANEBO LTD   (Japan)

^b GIFU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTIC ACID; CARBOHYDRATE DERIVATIVE; CERAMIDE DERIVATIVE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GLUTAMIC ACID; L SELECTIN; PADGEM PROTEIN;

ANIMAL CELL; ARTICLE; CELL STRAIN COS1; CHO CELL; CONTROLLED STUDY; DRUG DESIGN; DRUG SULFATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIGAND BINDING; NONHUMAN; SIALYLATION; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; UMBILICAL VEIN;

ANIMALS; CERAMIDES; DRUG DESIGN; E-SELECTIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; L-SELECTIN; LEWIS BLOOD-GROUP SYSTEM; MODELS, CHEMICAL; OLIGOSACCHARIDES; P-SELECTIN; RATS; SELECTINS; SOFTWARE; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; SULFATES;

EID: 15144345228     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9605290     Document Type: Article

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