Novel synthetic inhibitors of selectin-mediated cell adhesion: Synthesis of 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-α-D-mannopyranosyloxy)phenyl] hexane (TBC1269)

Journal of Medicinal Chemistry

Volumn 41, Issue 7, 1998, Pages 1099-1111

  Kogan, Timothy P ^a   Dupré, Brian ^a   Bui, Huong ^a   McAbee, Kathy L ^a   Kassir, Jamal M ^a   Scott, Ian L ^a   Hu, Xin ^a   Vanderslice, Peter ^a   Beck, Pamela J ^a,b   Dixon, Richard A F ^a  

^a TEXAS BIOTECHNOLOGY CORPORATION   (United States)

^b UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIMOSIAMOSE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; L SELECTIN; PADGEM PROTEIN; PROTEIN INHIBITOR; SELECTIN; SELECTIN ANTAGONIST; UNCLASSIFIED DRUG;

ARTICLE; CELL ADHESION; CELL STRAIN HL 60; DRUG DESIGN; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIGAND BINDING;

ANTI-ASTHMATIC AGENTS; ASTHMA; BIPHENYL COMPOUNDS; CELL ADHESION; HL-60 CELLS; HUMANS; MANNOSIDES; MODELS, MOLECULAR; SELECTINS;

EID: 14444268539     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm9704917     Document Type: Article

References (57)

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57. 8a are due to minor changes in the assay format. All data presented in this table are from multiple assays, and the values reported are consistent within this table.