Mouse and human granzyme B have distinct tetrapeptide specificities and abilities to recruit the bid pathway

Journal of Biological Chemistry

Volumn 282, Issue 7, 2007, Pages 4545-4552

  Casciola Rosen, Livia ^a   Garcia Calvo, Margarita ^b   Bull, Herbert G ^b   Becker, Joseph W ^b   Hines, Tonie ^a   Thornberry, Nancy A ^b   Rosen, Antony ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; CRYSTAL STRUCTURE; CYTOTOXICITY; DEGRADATION; POLYPEPTIDES; RATS;

HUMAN PROTEASE; LYMPHOCYTES;

ENZYME KINETICS;

ASPARTIC ACID; GRANZYME B; PROCASPASE 3; PROTEIN BID; PROTEINASE; TETRAPEPTIDE; BID PROTEIN, HUMAN; BID PROTEIN, MOUSE; CASPASE 3; GRANZYME; GZMB PROTEIN, MOUSE; GZMB PROTEIN, RAT; OLIGOPEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL ACTIVATION; CELL STIMULATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; CYTOTOXIC LYMPHOCYTE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; SITE DIRECTED MUTAGENESIS; SPECIES DIFFERENCE; ANIMAL; CELL DEATH; CHEMISTRY; COMPARATIVE STUDY; CYTOTOXIC T LYMPHOCYTE; ENZYMOLOGY; IMMUNOLOGY; LEUKEMIA CELL LINE; METABOLISM; RAT; SIGNAL TRANSDUCTION;

RATTUS;

ANIMALS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASE 3; CELL DEATH; GRANZYMES; HUMANS; JURKAT CELLS; MICE; OLIGOPEPTIDES; RATS; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; SUBSTRATE SPECIFICITY; T-LYMPHOCYTES, CYTOTOXIC;

EID: 33947496416     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M606564200     Document Type: Article

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