Maintenance of caspase-3 proenzyme dormancy by an intrinsic "safety catch" regulatory tripeptide

Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 11, 2001, Pages 6132-6137

  Roy, Sophie ^a   Bayly, Christopher I ^a   Gareau, Yves ^a   Houtzager, Vicky M ^a   Kargman, Stacia ^a   Keen, Sabina L C ^a   Rowland, Kathleen ^a   Seiden, Isolde M ^a   Thornberry, Nancy A ^b   Nicholson, Donald W ^a  

^a MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

^b MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; ENZYME PRECURSOR; TRIPEPTIDE;

AMINO TERMINAL SEQUENCE; APOPTOSIS; ARTICLE; ENZYME ACTIVATION; ENZYME CONFORMATION; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN DEGRADATION; STRUCTURE ACTIVITY RELATION;

AMINO ACID SEQUENCE; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CATALYSIS; CYSTEINE PROTEINASE INHIBITORS; ENZYME ACTIVATION; ENZYME PRECURSORS; HUMANS; HYDROGEN-ION CONCENTRATION; INTRACELLULAR FLUID; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN STRUCTURE, SECONDARY;

EID: 14344272939     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.111085198     Document Type: Article

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