Evidence for the role of aberrant DNA methylation in the pathogenesis of Lynch syndrome adenomas

International Journal of Cancer

Volumn 120, Issue 9, 2007, Pages 1922-1929

  Kaz, Andrew ^a,b   Kim, Young Ho ^a,c,d   Dzieciatkowski, Slavomir ^a   Lynch, Henry ^e   Watson, Patrice ^e   Washington, Mary Kay ^f   Lin, Li ^a   Grady, William M ^a,b,g  

^a Fred Hutchinson Cancer Research Center   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

^c Samsung Medical Center   (South Korea)

^d Sungkyunkwan University School of Medicine   (South Korea)

^e CREIGHTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^f VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g VA PUGET SOUND HEALTH CARE SYSTEM   (United States)

Author keywords

Adenoma; Colon cancer; DNA methylation; HNPCC; Lynch syndrome

Indexed keywords

ADULT; ARTICLE; CDKN2A GENE; COLON CARCINOGENESIS; COLON POLYP; COLORECTAL CANCER; DNA METHYLATION; EPIGENETICS; FAMILIAL CANCER; FEMALE; GENE; GENE MUTATION; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MGMT GENE; MLH1 GENE; MSH2 GENE; P14ARF GENE; PRIORITY JOURNAL; UNITED STATES;

ADENOMA; ADULT; AGED; CARRIER PROTEINS; COLONIC NEOPLASMS; COLORECTAL NEOPLASMS, HEREDITARY NONPOLYPOSIS; DNA METHYLATION; FEMALE; GENES, P16; HUMANS; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGED; NUCLEAR PROTEINS; TUMOR SUPPRESSOR PROTEIN P14ARF;

EID: 33947218541     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.22544     Document Type: Article

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