Sphingolipid storage induces accumulation of intracellular cholesterol by stimulating SREBP-1 cleavage

Journal of Biological Chemistry

Volumn 278, Issue 23, 2003, Pages 20961-20970

  Puri, Vishwajeet ^c   Jefferson, John R ^a   Singh, Raman Deep ^c   Wheatley, Christine L ^c   Marks, David L ^c   Pagano, Richard E ^b  

^a LUTHER COLLEGE   (United States)

^b MAYO CLINIC   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; PROTEINS; SYNTHESIS (CHEMICAL);

LYSOSOMES;

BIOCHEMISTRY;

CERAMIDE GLUCOSYLTRANSFERASE INHIBITOR; CHOLESTEROL; LOW DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; SPHINGOLIPID; STEROL REGULATORY ELEMENT BINDING PROTEIN; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; CELL LEVEL; CHOLESTEROL ESTERIFICATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CULTURE MEDIUM; ENDOPLASMIC RETICULUM; ENDOSOME; HUMAN; HUMAN CELL; LIPIDOSIS; LIPOLYSIS; LYSOSOME; PRIORITY JOURNAL; PROTEIN DEGRADATION; SKIN FIBROBLAST; UPREGULATION;

CCAAT-ENHANCER-BINDING PROTEINS; CELLS, CULTURED; CHOLESTEROL; DNA-BINDING PROTEINS; ESTERIFICATION; FIBROBLASTS; G(M1) GANGLIOSIDE; HUMANS; RECEPTORS, LDL; SKIN; SPHINGOLIPIDS; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 0038756797     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M300304200     Document Type: Article

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