Misfolding diverts CFTR from recycling to degradation: Quality control at early endosomes

Journal of Cell Biology

Volumn 164, Issue 6, 2004, Pages 923-933

  Sharma, Manu ^a,b   Pampinella, Francesca ^a,b   Nemes, Csilla ^a,b   Benharouga, Mohamed ^a,b   So, Jeffrey ^a   Du, Kai ^a   Bache, Kristi G ^d   Papsin, Blake ^a   Zerangue, Noa ^c   Stenmark, Harald ^d   Lukacs, Gergely L ^a,b,e  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d OSLO UNIVERSITY HOSPITAL   (Norway)

^e HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

Endocytosis; Mutation; Recycling; Sorting; Ubiquitin receptors

Indexed keywords

CYCLOHEXIMIDE; GLUTATHIONE TRANSFERASE; MEMBRANE PROTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL CELL; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL STRAIN BHK; ENDOSOME; GOLGI COMPLEX; IMMUNOPRECIPITATION; INTERNALIZATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FOLDING; QUALITY CONTROL; RESPIRATORY EPITHELIUM;

ANIMALS; CELL LINE; CELL MEMBRANE; CRICETINAE; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; ENDOCYTOSIS; ENDOSOMES; EPITHELIAL CELLS; GOLGI APPARATUS; HUMANS; LYSOSOMES; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; UBIQUITINS;

ANIMALIA;

EID: 12144287602     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200312018     Document Type: Article

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