Cholesterol depletion facilitates ubiquitylation of NPC1 and its association with SKD1/Vps4

Journal of Cell Science

Volumn 119, Issue 13, 2006, Pages 2643-2653

  Ohsaki, Yuki ^a   Sugimoto, Yuko ^a   Suzuki, Michitaka ^a   Hosokawa, Hiroshi ^b   Yoshimoro, Tamotsu ^c   Davies, Joanna P ^d   Ioannou, Yiannis A ^d   Vanier, Marie T ^e   Ohno, Kousaku ^a   Ninomiya, Haruaki ^a  

^a TOTTORI UNIVERSITY   (Japan)

^b KYOTO UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF GENETICS   (Japan)

^d MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^e INSERM   (France)

Author keywords

Cholesterol; NPC1; NPC2; SKD1; Ubiquitin; Vps4

Indexed keywords

AMINO ACID; CHOLESTEROL; GLYCOPROTEIN; MEMBRANE PROTEIN; PROTEIN NPC1; PROTEIN NPC2; STEROL; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL STRAIN COS1; CONTROLLED STUDY; ENDOSOME; HUMAN; HUMAN CELL; MUTANT; NIEMANN PICK DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN TRANSPORT; REGULATORY MECHANISM; SKIN FIBROBLAST; UBIQUITINATION; WILD TYPE;

ADENOSINE TRIPHOSPHATASES; ANIMALS; CARRIER PROTEINS; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; CHOLESTEROL; COS CELLS; ENDOSOMES; FIBROBLASTS; GLYCOPROTEINS; HUMANS; LEUPEPTINS; MEMBRANE GLYCOPROTEINS; MUTANT PROTEINS; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; REPRESSOR PROTEINS; SKIN; UBIQUITIN;

EID: 33746911531     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.02993     Document Type: Article

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