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Volumn 7, Issue 1, 2007, Pages 56-65

Influence of polymorphisms of ABCB1 and ABCC2 on mRNA and protein expression in normal and cancerous kidney cortex

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ANTINEOPLASTIC AGENT; CYSTEINE; DNA; GLYCINE; ISOLEUCINE; MESSENGER RNA; MULTIDRUG RESISTANCE PROTEIN 1; MULTIDRUG RESISTANCE PROTEIN 2; SERINE; THREONINE; VALINE; XENOBIOTIC AGENT;

EID: 33847249931     PISSN: 1470269X     EISSN: 14731150     Source Type: Journal    
DOI: 10.1038/sj.tpj.6500403     Document Type: Article
Times cited : (149)

References (47)
  • 3
    • 0344927562 scopus 로고    scopus 로고
    • Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance
    • Konig J, Nies AT, Cui Y, Leier I, Keppler D. Conjugate export pumps of the multidrug resistance protein (MRP) family: Localization, substrate specificity, and MRP2-mediated drug resistance. Biochim Biophys Acta 1999; 1461: 377-394.
    • (1999) Biochim Biophys Acta , vol.1461 , pp. 377-394
    • Konig, J.1    Nies, A.T.2    Cui, Y.3    Leier, I.4    Keppler, D.5
  • 6
    • 0030832802 scopus 로고    scopus 로고
    • Expression of the conjugate export pump encoded by the mrp2 gene in the apical membrane of kidney proximal tubules
    • Schaub TP, Kartenbeck J, Konig J, Vogel O, Witzgall R, Kriz W et al. Expression of the conjugate export pump encoded by the mrp2 gene in the apical membrane of kidney proximal tubules. J Am Soc Nephrol 1997; 8: 1213-1221.
    • (1997) J Am Soc Nephrol , vol.8 , pp. 1213-1221
    • Schaub, T.P.1    Kartenbeck, J.2    Konig, J.3    Vogel, O.4    Witzgall, R.5    Kriz, W.6
  • 7
    • 0033032730 scopus 로고    scopus 로고
    • Expression of the MRP2 gene-encoded conjugate export pump in human kidney proximal tubules and in renal cell carcinoma
    • Schaub TP, Kartenbeck J, Konig J, Spring H, Dorsam J, Staehler G et al. Expression of the MRP2 gene-encoded conjugate export pump in human kidney proximal tubules and in renal cell carcinoma. J Am Soc Nephrol 1999; 10: 1159-1169.
    • (1999) J Am Soc Nephrol , vol.10 , pp. 1159-1169
    • Schaub, T.P.1    Kartenbeck, J.2    Konig, J.3    Spring, H.4    Dorsam, J.5    Staehler, G.6
  • 8
    • 0345299165 scopus 로고    scopus 로고
    • Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug rsistance protein, MRP2, permanently expressed in human and canine cells
    • Cui Y, Konig J, Buchholz JK, Spring H, Leier I, Keppler D. Drug resistance and ATP-dependent conjugate transport mediated by the apical multidrug rsistance protein, MRP2, permanently expressed in human and canine cells. Mol Pharmacol 1999; 55: 929-937.
    • (1999) Mol Pharmacol , vol.55 , pp. 929-937
    • Cui, Y.1    Konig, J.2    Buchholz, J.K.3    Spring, H.4    Leier, I.5    Keppler, D.6
  • 9
    • 33645830172 scopus 로고
    • A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants
    • Juliano RL, Ling V. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochim Biophys Acta 1976; 455: 152-162.
    • (1976) Biochim Biophys Acta , vol.455 , pp. 152-162
    • Juliano, R.L.1    Ling, V.2
  • 10
    • 0034724324 scopus 로고    scopus 로고
    • Functional polymorphisms of the human multidrug-resitance gene: Multiple sequence variations and correlation of one allele with p-glycoprotein expression and activity in vivo
    • Hoffmeyer S, Burk O, von Richter O, Arnold HP, Brockmoller J, Johne A et al. Functional polymorphisms of the human multidrug-resitance gene: multiple sequence variations and correlation of one allele with p-glycoprotein expression and activity in vivo. Proc Natl Acad Sci USA 2000; 97: 3473-3478.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 3473-3478
    • Hoffmeyer, S.1    Burk, O.2    von Richter, O.3    Arnold, H.P.4    Brockmoller, J.5    Johne, A.6
  • 11
    • 0036881149 scopus 로고    scopus 로고
    • Modulation of steady-state kinetics of digoxin by haplotype of the P-glycopotein MDR1 gene
    • Johne A, Kopke K, Gerloff T, Mai I, Rietbrock, Meisel C et al. Modulation of steady-state kinetics of digoxin by haplotype of the P-glycopotein MDR1 gene. Clin Pharmacol Ther 2002; 72: 584-594.
    • (2002) Clin Pharmacol Ther , vol.72 , pp. 584-594
    • Johne, A.1    Kopke, K.2    Gerloff, T.3    Mai, I.4    Rietbrock, S.5    Meisel, C.6
  • 13
    • 25144433260 scopus 로고    scopus 로고
    • Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability
    • Wang D, Johnson AD, Papp AC, Kroetz DL, Sadee W. Multidrug resistance polypeptide 1 (MDR1, ABCB1) variant 3435C>T affects mRNA stability. Pharmacogenet Genom 2005; 15; 693-704.
    • (2005) Pharmacogenet Genom , vol.15 , pp. 693-704
    • Wang, D.1    Johnson, A.D.2    Papp, A.C.3    Kroetz, D.L.4    Sadee, W.5
  • 14
    • 10744229154 scopus 로고    scopus 로고
    • Common single nucleotide polymorphims of the MDR1 gene have no influence on its mRNA expression level of normal kiidney cortex and renal cell carcinoma ian Japanese nephrectomized patients
    • Uwai Y, Masuda S, Goto M, Motohashi H, Saito H, Okuda M et al. Common single nucleotide polymorphims of the MDR1 gene have no influence on its mRNA expression level of normal kiidney cortex and renal cell carcinoma ian Japanese nephrectomized patients. J Hum Genet 2004; 49: 40-45.
    • (2004) J Hum Genet , vol.49 , pp. 40-45
    • Uwai, Y.1    Masuda, S.2    Goto, M.3    Motohashi, H.4    Saito, H.5    Okuda, M.6
  • 15
    • 18444404305 scopus 로고    scopus 로고
    • Association of the P-glycoprotein transporter MDR1(C3435T) polymorphism with the susceptability to renal epithelial tumors
    • Siegmund M, Brinkmann U, Schaffeler E, Weirich G, Schwab M, Eichelbaum M et al. Association of the P-glycoprotein transporter MDR1(C3435T) polymorphism with the susceptability to renal epithelial tumors. J Am Soc Nephrol 2002; 13: 1847-1854.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1847-1854
    • Siegmund, M.1    Brinkmann, U.2    Schaffeler, E.3    Weirich, G.4    Schwab, M.5    Eichelbaum, M.6
  • 17
    • 0029189915 scopus 로고
    • Morphological classification of renal cancer
    • Storkel S, van den BE. Morphological classification of renal cancer. World J Urol 11995; 3: 153-158.
    • (1995) World J Urol , vol.3 , pp. 153-158
    • Storkel, S.1    van Den, B.E.2
  • 18
    • 0033583793 scopus 로고    scopus 로고
    • Trichloroethylene exposure and specific somatic mutations in patients with renal cell carcinoma
    • Brauch H, Weirich G, Hornauer MA, Storkel S, Wohl T, Bruning T. Trichloroethylene exposure and specific somatic mutations in patients with renal cell carcinoma. J Natl Cancer int 1999; 91: 854-861.
    • (1999) J Natl Cancer Int , vol.91 , pp. 854-861
    • Brauch, H.1    Weirich, G.2    Hornauer, M.A.3    Storkel, S.4    Wohl, T.5    Bruning, T.6
  • 19
    • 0030900929 scopus 로고    scopus 로고
    • Renal cell carcinoma in tichloroethene (TRI) exposed perons are associated with somatic mutations in the von Hippel-Lindau (VHL) tumour suppressor gene
    • Bruning T, Weirich G, Hornauer MA, Hofler H, Brauch H. Renal cell carcinoma in tichloroethene (TRI) exposed perons are associated with somatic mutations in the von Hippel-Lindau (VHL) tumour suppressor gene. Arch Toxicol 1997; 71: 332-335.
    • (1997) Arch Toxicol , vol.71 , pp. 332-335
    • Bruning, T.1    Weirich, G.2    Hornauer, M.A.3    Hofler, H.4    Brauch, H.5
  • 20
    • 0033918360 scopus 로고    scopus 로고
    • Risk factors for adult renal cell carcinoma: A systematic review and implications for prevention
    • Dhote R, Pellicer-Coeuret M, Thiounn N, Debre B, Vidal-Trecan G. Risk factors for adult renal cell carcinoma: A systematic review and implication for prevention. BJU Int 2000; 86: 20-27.
    • (2000) BJU Int , vol.86 , pp. 20-27
    • Dhote, R.1    Pellicer-Coeuret, M.2    Thiounn, N.3    Debre, B.4    Vidal-Trecan, G.5
  • 21
    • 0035104031 scopus 로고    scopus 로고
    • Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transpoter MDR1 gene in white subjects
    • Cascorbi I, Gerloff T, Johne A, Meisel C, Hoffmeyer S, Schwab M et al. Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transpoter MDR1 gene in white subjects. Clin Pharmacol Ther 200; 69: 169-174.
    • (2000) Clin Pharmacol Ther , vol.69 , pp. 169-174
    • Cascorbi, I.1    Gerloff, T.2    Johne, A.3    Meisel, C.4    Hoffmeyer, S.5    Schwab, M.6
  • 22
    • 1942467691 scopus 로고    scopus 로고
    • Genetic polymorphism at the 5′ regulatory region of multidrug resistance 1 (MDR1) and its association with interindiviidual variation of expression level in the colon
    • Taniguchi S, Mochida Y, Uchiumi T, Tahira T, Hayashi K, Takagi K et al. Genetic polymorphism at the 5′ regulatory region of multidrug resistance 1 (MDR1) and its association with interindiviidual variation of expression level in the colon. Mol Cancer Ther 2003; 2: 1351-1359.
    • (2003) Mol Cancer Ther , vol.2 , pp. 1351-1359
    • Taniguchi, S.1    Mochida, Y.2    Uchiumi, T.3    Tahira, T.4    Hayashi, K.5    Takagi, K.6
  • 24
    • 4544271508 scopus 로고    scopus 로고
    • Expression of multidrug tansporters in dysembryoplastic neuroepithelial tumors causing intractable epilepsy
    • Vogelgesang S, Kunert-Keil C, Cascorbi I, Mosyagin I, Chroder E, Runge U et al. Expression of multidrug tansporters in dysembryoplastic neuroepithelial tumors causing intractable epilepsy. Clin Neuropathol 2004; 23: 223-231.
    • (2004) Clin Neuropathol , vol.23 , pp. 223-231
    • Vogelgesang, S.1    Kunert-Keil, C.2    Cascorbi, I.3    Mosyagin, I.4    Chroder, E.5    Runge, U.6
  • 25
    • 0037129827 scopus 로고    scopus 로고
    • Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
    • RESEARCCH0034.1-RESEARCCH0034.11
    • Vandesompele J, De Preter K, Pattyn F, Poppe B, Van Roy N, De Paepe A et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol 2002; 3: RESEARCCH0034.1-RESEARCCH0034.11.
    • (2002) Genome Biol , vol.3
    • Vandesompele, J.1    De Preter, K.2    Pattyn, F.3    Poppe, B.4    Van Roy, N.5    De Paepe, A.6
  • 27
    • 0030663088 scopus 로고    scopus 로고
    • Expression of MDR1 (multidrug resistance) gene and it protein in normal human kidney
    • Ernest S, Rajaraman S, Megyesi J, Bello-Reuss EN. Expression of MDR1 (multidrug resistance) gene and it protein in normal human kidney. Nephron 1997; 77: 284-289.
    • (1997) Nephron , vol.77 , pp. 284-289
    • Ernest, S.1    Rajaraman, S.2    Megyesi, J.3    Bello-Reuss, E.N.4
  • 28
    • 22344433760 scopus 로고    scopus 로고
    • Induction of the multidrug resistance-associated protein family of transpoters by chemical activators of receptor-mediated pathways in mouse liver
    • Maher JM, Cheng X, Slitt AL, Dieter MZ, Klaassen CD. Induction of the multidrug resistance-associated protein family of transpoters by chemical activators of receptor-mediated pathways in mouse liver. Drug Metab Dispos 2005; 33: 956-962.
    • (2005) Drug Metab Dispos , vol.33 , pp. 956-962
    • Maher, J.M.1    Cheng, X.2    Slitt, A.L.3    Dieter, M.Z.4    Klaassen, C.D.5
  • 29
    • 0036019498 scopus 로고    scopus 로고
    • Xenobiotic export pumps, endothelin signaling, and tubular nephrotoxicants - A case of molecular hijacking
    • Miller DS. Xenobiotic export pumps, endothelin signaling, and tubular nephrotoxicants - a case of molecular hijacking. J Biochem Mol Toxicol 2002; 16: 121-127.
    • (2002) J Biochem Mol Toxicol , vol.16 , pp. 121-127
    • Miller, D.S.1
  • 30
    • 4944230477 scopus 로고    scopus 로고
    • Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier
    • Bauer B, Hartz AM, Fricker G, Miller DS. Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier. Mol Pharmacol 2004; 66: 413-419.
    • (2004) Mol Pharmacol , vol.66 , pp. 413-419
    • Bauer, B.1    Hartz, A.M.2    Fricker, G.3    Miller, D.S.4
  • 31
    • 0034708264 scopus 로고    scopus 로고
    • Interleukin-1 beta uppresses retinoid transactivation of two hepatic transporter genes involved in bile formation
    • Denson LA, Auld KL, Schiek DS, McClure MH, Mangelsdorf DJ, Karpen SJ. Interleukin-1 beta uppresses retinoid transactivation of two hepatic transporter genes involved in bile formation. J Biol Chem 2000; 275: 8835-8843.
    • (2000) J Biol Chem , vol.275 , pp. 8835-8843
    • Denson, L.A.1    Auld, K.L.2    Schiek, D.S.3    McClure, M.H.4    Mangelsdorf, D.J.5    Karpen, S.J.6
  • 32
    • 0031730608 scopus 로고    scopus 로고
    • Protein kinase C regulation of p-glycoprotein-mediated xenobiotic secretion in renal proximal tubule
    • Miller DS, Sussman CR, Renfro JL. Protein kinase C regulation of p-glycoprotein-mediated xenobiotic secretion in renal proximal tubule. Am J Physiol 1998; 275: F785-F795.
    • (1998) Am J Physiol , vol.275
    • Miller, D.S.1    Sussman, C.R.2    Renfro, J.L.3
  • 35
    • 3042600927 scopus 로고    scopus 로고
    • Modulation of multudrug resistance P-glycoprotein 1 (ABCB1) expression in human heart hereditary polymorphisms
    • Meissner K, Jedlitschky G, Meyer zu SH, Dazert P, Eckel L, Vogelgesang S et al. Modulation of multudrug resistance P-glycoprotein 1 (ABCB1) expression in human heart hereditary polymorphisms. Pharmacogenetics 2004; 14: 381-385.
    • (2004) Pharmacogenetics , vol.14 , pp. 381-385
    • Meissner, K.1    Jedlitschky, G.2    Meyer zu, S.H.3    Dazert, P.4    Eckel, L.5    Vogelgesang, S.6
  • 36
    • 0036224114 scopus 로고    scopus 로고
    • Effect of the mutation (C3435T) at exon 26 of the duodenal enterocytes of healthy Japanese subjects
    • Nakamura T, Sakaeda T, Horinouchi M, Tamura T, Aoyama N, Shirakawa T et al, effect of the mutation (C3435T) at exon 26 of the duodenal enterocytes of healthy Japanese subjects. Clin Pharmacol Ther 2002; 71: 297-303.
    • (2002) Clin Pharmacol Ther , vol.71 , pp. 297-303
    • Nakamura, T.1    Sakaeda, T.2    Horinouchi, M.3    Tamura, T.4    Aoyama, N.5    Shirakawa, T.6
  • 37
    • 0031803072 scopus 로고    scopus 로고
    • Post-transcriptional gene regulatory mechanisms in eukaryotes: An overview
    • Daya DA, Tuite MF. Post-transcriptional gene regulatory mechanisms in eukaryotes: An overview. J Endocrinol 1998; 157: 361-371.
    • (1998) J Endocrinol , vol.157 , pp. 361-371
    • Daya, D.A.1    Tuite, M.F.2
  • 38
    • 9644257647 scopus 로고    scopus 로고
    • An MDR-EGFP gene fusion allows for direct cellular localization. function and stability assessment of P-glycoprotein
    • Petriz J, Gottesman MM, Aran JM. An MDR-EGFP gene fusion allows for direct cellular localization, function and stability assessment of P-glycoprotein. Curr Drug deliv 2004; 1: 43-56.
    • (2004) Curr Drug Deliv , vol.1 , pp. 43-56
    • Petriz, J.1    Gottesman, M.M.2    Aran, J.M.3
  • 39
    • 0037022006 scopus 로고    scopus 로고
    • Response to antiretroviral treatment in HIV-1 -infected individuals with allelic variants of the multidrug resistance transporter 1: A pharmacogenetics study
    • Fellay J, Marzolini C, Meaden ER, Back DJ, Buclin T, Chave JP et al. Response to antiretroviral treatment in HIV-1 -infected individuals with allelic variants of the multidrug resistance transporter 1: A pharmacogenetics study. Lancet 2002; 359: 30-36.
    • (2002) Lancet , vol.359 , pp. 30-36
    • Fellay, J.1    Marzolini, C.2    Meaden, E.R.3    Back, D.J.4    Buclin, T.5    Chave, J.P.6
  • 40
    • 0034971274 scopus 로고    scopus 로고
    • The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells
    • Hitzl M, Drescher S, van De KH, Schaffeler E, Fischer J, Schwab M et al. The C3435T mutation in the human MDR1 gene is associated with altered efflux of the P-glycoprotein substrate rhodamine 123 from CD56+ natural killer cells. Pharmacogenetics 2001; 11: 293-298.
    • (2001) Pharmacogenetics , vol.11 , pp. 293-298
    • Hitzl, M.1    Drescher, S.2    van De, K.H.3    Schaffeler, E.4    Fischer, J.5    Schwab, M.6
  • 41
    • 0036667955 scopus 로고    scopus 로고
    • MDR1 single nucleotide polymorphisms: Multiplicity of haplotypes and functional consequences
    • Kim RB. MDR1 single nucleotide polymorphisms: Multiplicity of haplotypes and functional consequences. Pharmacogenetics 2002; 12: 425-427.
    • (2002) Pharmacogenetics , vol.12 , pp. 425-427
    • Kim, R.B.1
  • 42
    • 3042772026 scopus 로고    scopus 로고
    • Identification of functionally variant MDR1 alleles among European Americans and African Americans
    • Kim RB, Leake BF, Choo EF, Dresser GK, Kubba SV, Schwarz UI et al. Identification of functionally variant MDR1 alleles among European Americans and African Americans. Clin Pharmacol Ther 2001; 70: 189-199.
    • (2001) Clin Pharmacol Ther , vol.70 , pp. 189-199
    • Kim, R.B.1    Leake, B.F.2    Choo, E.F.3    Dresser, G.K.4    Kubba, S.V.5    Schwarz, U.I.6
  • 43
    • 0035103009 scopus 로고    scopus 로고
    • Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects
    • Ito S, Ieiri I, Tanabe M, Suzuki A, Higuchi S, Otsubo K. Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects. Pharmacogenetics 2001; 11: 175-184.
    • (2001) Pharmacogenetics , vol.11 , pp. 175-184
    • Ito, S.1    Ieiri, I.2    Tanabe, M.3    Suzuki, A.4    Higuchi, S.5    Otsubo, K.6
  • 44
    • 0036206860 scopus 로고    scopus 로고
    • Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: An association between single nucleotide polymorphisms in the 5′-untranslated region and exon 28
    • Itoda M, Saito Y, Soyama A, Saeki M, Murayama N, Ishida S et al. Polymorphisms in the ABCC2 (cMOAT/MRP2) gene found in 72 established cell lines derived from Japanese individuals: An association between single nucleotide polymorphisms in the 5′-untranslated region and exon 28. Drug Metab Dispos 2002; 30: 363-364.
    • (2002) Drug Metab Dispos , vol.30 , pp. 363-364
    • Itoda, M.1    Saito, Y.2    Soyama, A.3    Saeki, M.4    Murayama, N.5    Ishida, S.6
  • 45
    • 0042329814 scopus 로고    scopus 로고
    • Functional significance of a hereditary adenine inertion variant in the 5′-UTR of the endothelin-1 gene
    • Popowski K, Sperker B, Kroemer HK, John U, Laule M, Stangl K et al. Functional significance of a hereditary adenine inertion variant in the 5′-UTR of the endothelin-1 gene. Pharmacogenetics 2003; 13: 445-451.
    • (2003) Pharmacogenetics , vol.13 , pp. 445-451
    • Popowski, K.1    Sperker, B.2    Kroemer, H.K.3    John, U.4    Laule, M.5    Stangl, K.6
  • 46
    • 0041328869 scopus 로고    scopus 로고
    • Constitutive rat multidrug-resistance protein 2 gene transcription is down-regulated by Y-box protein 1. biochem
    • Geier A, Mertens PR, Gerloff T, Dietrich CG, En-Nia A, Kullak-Ublick GA et al. Constitutive rat multidrug-resistance protein 2 gene transcription is down-regulated by Y-box protein 1. biochem Biophys Res Commmun 2003; 309: 612-618.
    • (2003) Biophys Res Commmun , vol.309 , pp. 612-618
    • Geier, A.1    Mertens, P.R.2    Gerloff, T.3    Dietrich, C.G.4    En-Nia, A.5    Kullak-Ublick, G.A.6
  • 47
    • 0031887288 scopus 로고    scopus 로고
    • P-glycoprotein: A new mechanism to contol drug-induced nephrotoxicity
    • del Moral RG, Olmo A, Aguilar M, O'Valle F. P-glycoprotein: A new mechanism to contol drug-induced nephrotoxicity. Exp Nephrol 1998; 6: 89-97.
    • (1998) Exp Nephrol , vol.6 , pp. 89-97
    • del Moral, R.G.1    Olmo, A.2    Aguilar, M.3    O'Valle, F.4


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