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Volumn 6, Issue 2, 1998, Pages 89-97

P glycoprotein: A new mechanism to control drug-induced nephrotoxicity

Author keywords

Angiotensin II; Cyclosporin A; Nephrotoxicity; P glycoprotein; Tacrolimus

Indexed keywords

AMIODARONE; AZIDOPINE; COLCHICINE; CYCLOSPORIN A; DACTINOMYCIN; DAUNORUBICIN; DOXORUBICIN; EMETINE; ETOPOSIDE; GLYCOPROTEIN P; MITHRAMYCIN; MITOMYCIN C; MITOXANTRONE; NIFEDIPINE; PACLITAXEL; PROGESTERONE; PROTEIN KINASE C; PUROMYCIN; QUINIDINE; RAPAMYCIN; TACROLIMUS; TENIPOSIDE; TOPOTECAN; VERAPAMIL; VINBLASTINE; VINCRISTINE;

EID: 0031887288     PISSN: 10187782     EISSN: None     Source Type: Journal    
DOI: 10.1159/000020510     Document Type: Short Survey
Times cited : (47)

References (59)
  • 1
    • 0014767029 scopus 로고
    • Cellular resistance to actinomycin D in Chinese hamster cells in vitro: Cross-resistance, radioautographic and cytogenetic studies
    • Biedler JL Riehm H: Cellular resistance to actinomycin D in Chinese hamster cells in vitro: Cross-resistance, radioautographic and cytogenetic studies. Cancer Res 1970;30:1174-1184.
    • (1970) Cancer Res , vol.30 , pp. 1174-1184
    • Biedler, J.L.1    Riehm, H.2
  • 3
    • 0029954843 scopus 로고    scopus 로고
    • P-glycoprotein: A mediator of multidrug resistance in tumour cells
    • Germann UA: P-glycoprotein: A mediator of multidrug resistance in tumour cells. Eur J Cancer [A] 1996;32:927-944.
    • (1996) Eur J Cancer [A] , vol.32 , pp. 927-944
    • Germann, U.A.1
  • 5
    • 0026621245 scopus 로고
    • ABC transporters: From microorganisms to man
    • Higgins CF: ABC transporters: From microorganisms to man. Annu Rev Cell Biol 1992;8:67-113.
    • (1992) Annu Rev Cell Biol , vol.8 , pp. 67-113
    • Higgins, C.F.1
  • 6
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman MM, Pastan I: Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu Rev Biochem 1993;62:385-427.
    • (1993) Annu Rev Biochem , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 7
    • 0023813001 scopus 로고
    • Characterization of the ATPase activity of the Mr 170,000 to 180,000 membrane glycoprotein (P-glycoprotein) associated with multidrug resistance in K562/ ADM cells
    • Hamada H, Tsuruo T: Characterization of the ATPase activity of the Mr 170,000 to 180,000 membrane glycoprotein (P-glycoprotein) associated with multidrug resistance in K562/ ADM cells. Cancer Res 1988;48:4926-4932.
    • (1988) Cancer Res , vol.48 , pp. 4926-4932
    • Hamada, H.1    Tsuruo, T.2
  • 8
    • 0030052091 scopus 로고    scopus 로고
    • P-glycoprotein, multidrug resistance and protein kinase C
    • Fine RL, Chambers TC, Sachs CW: P-glycoprotein, multidrug resistance and protein kinase C. Stem Cells 1996;14:47-55.
    • (1996) Stem Cells , vol.14 , pp. 47-55
    • Fine, R.L.1    Chambers, T.C.2    Sachs, C.W.3
  • 9
    • 0027005480 scopus 로고
    • Activation of MDR1 (P-glycoprotein) gene expression m human cells by protein kinase C agonists
    • Chaudhary PM, Roninson IB: Activation of MDR1 (P-glycoprotein) gene expression m human cells by protein kinase C agonists. Oncol Res 1992;4:281-290.
    • (1992) Oncol Res , vol.4 , pp. 281-290
    • Chaudhary, P.M.1    Roninson, I.B.2
  • 10
    • 0029966245 scopus 로고    scopus 로고
    • Reduced daunomycin accumulation in drug-sensitive and multidrug-resistant human carcinoma KB cells following phorbol ester treatment: A potential role for protein-kinase-C in reducing drug influx
    • Drew L, Groome N, Warr JR, Rumsby MG: Reduced daunomycin accumulation in drug-sensitive and multidrug-resistant human carcinoma KB cells following phorbol ester treatment: A potential role for protein-kinase-C in reducing drug influx. Oncol Res 1996;8:249-257.
    • (1996) Oncol Res , vol.8 , pp. 249-257
    • Drew, L.1    Groome, N.2    Warr, J.R.3    Rumsby, M.G.4
  • 11
    • 0030002145 scopus 로고    scopus 로고
    • Expression, subcellular distribution and response to phorbol esters of protein-kinase-C (PKC) isoenzymes in drug-sensitive and multidrug-resistant KB cells: Evidence for altered regulation of PKC-alpha
    • Cloudheflin BA, McMasters RA, Osborn HT, Chambers TC: Expression, subcellular distribution and response to phorbol esters of protein-kinase-C (PKC) isoenzymes in drug-sensitive and multidrug-resistant KB cells: Evidence for altered regulation of PKC-alpha. Eur J Biochem 1996;239:796-804.
    • (1996) Eur J Biochem , vol.239 , pp. 796-804
    • Cloudheflin, B.A.1    McMasters, R.A.2    Osborn, H.T.3    Chambers, T.C.4
  • 13
    • 0029889967 scopus 로고    scopus 로고
    • Protem-kinase-C-mediated phosphorylation does not regulate drug transport by the human multidrug resistance P-glycoprotein
    • Goodfellow HR, Sardini A, Ruetz S, Callaghan R, Gros P, McNaughton PA, Higgins CF: Protem-kinase-C-mediated phosphorylation does not regulate drug transport by the human multidrug resistance P-glycoprotein. J Biol Chem 1996;271:13668-13674.
    • (1996) J Biol Chem , vol.271 , pp. 13668-13674
    • Goodfellow, H.R.1    Sardini, A.2    Ruetz, S.3    Callaghan, R.4    Gros, P.5    McNaughton, P.A.6    Higgins, C.F.7
  • 16
    • 0028149617 scopus 로고
    • P-glycoprotein-mediated multidrug resistance in normal and neoplastic hematopoietic cells
    • Litcht T, Pastan I, Gottesman MM, Herrmann F: P-glycoprotein-mediated multidrug resistance in normal and neoplastic hematopoietic cells. Ann Hematol 1994;69:159-171.
    • (1994) Ann Hematol , vol.69 , pp. 159-171
    • Litcht, T.1    Pastan, I.2    Gottesman, M.M.3    Herrmann, F.4
  • 17
    • 0028210704 scopus 로고
    • P-glycoprotein expression and function in circulating blood cells from normal volunteers
    • Klimecki WT, Futscher BW, Grogan TM, Dalton WS: P-glycoprotein expression and function in circulating blood cells from normal volunteers. Blood 1994;83:2451-2458.
    • (1994) Blood , vol.83 , pp. 2451-2458
    • Klimecki, W.T.1    Futscher, B.W.2    Grogan, T.M.3    Dalton, W.S.4
  • 19
    • 0007544439 scopus 로고    scopus 로고
    • Mdrl P-glycoprotein is a lipid translocase of broad specificity, while mdr3 P-glycoprotein specifically translocates phosphatidylcholine
    • Vanhelvoort A, Smith AJ, Sprong H, Fritzsche I, Schinkel AH, Borst P, Vanmeer G: mdrl P-glycoprotein is a lipid translocase of broad specificity, while mdr3 P-glycoprotein specifically translocates phosphatidylcholine. Cell 1996;87:507-517.
    • (1996) Cell , vol.87 , pp. 507-517
    • Vanhelvoort, A.1    Smith, A.J.2    Sprong, H.3    Fritzsche, I.4    Schinkel, A.H.5    Borst, P.6    Vanmeer, G.7
  • 20
    • 0029860174 scopus 로고    scopus 로고
    • Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdrlA P-glycoprotein
    • Mayer U, Wagenaar E, Beijnen JH, Smit JW, Meijer DKF, Vaanasperen J, Borst P, Schinkel AH: Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdrlA P-glycoprotein. Br J Pharmacol 1996;119:1038-1044.
    • (1996) Br J Pharmacol , vol.119 , pp. 1038-1044
    • Mayer, U.1    Wagenaar, E.2    Beijnen, J.H.3    Smit, J.W.4    Meijer, D.K.F.5    Vaanasperen, J.6    Borst, P.7    Schinkel, A.H.8
  • 21
  • 22
    • 0026584396 scopus 로고
    • Cyclosporins as drug resistance modifiers
    • Twentyman PR: Cyclosporins as drug resistance modifiers. Biochem Pharmacol 1992;43:109-117.
    • (1992) Biochem Pharmacol , vol.43 , pp. 109-117
    • Twentyman, P.R.1
  • 23
    • 0029910521 scopus 로고    scopus 로고
    • Homologues of the human multidrug resistance genes MRP and MDR contribute to heavy metal resistance in the soil nematode Caenorhabditis elegans
    • Broeks A, Gerrard B, Allikmets R, Dean M, Plasterk RHA: Homologues of the human multidrug resistance genes MRP and MDR contribute to heavy metal resistance in the soil nematode Caenorhabditis elegans. EMBO J 1996;15:6132-6143.
    • (1996) EMBO J , vol.15 , pp. 6132-6143
    • Broeks, A.1    Gerrard, B.2    Allikmets, R.3    Dean, M.4    Plasterk, R.H.A.5
  • 27
    • 0026353397 scopus 로고
    • P-glycoprotein expression is increased in human secretory and gestational endometrium
    • Axiotis CA, Guarch R, Merino MJ, Laporte N, Neumann RD: P-glycoprotein expression is increased in human secretory and gestational endometrium. Lab Invest 1991;65:577-581.
    • (1991) Lab Invest , vol.65 , pp. 577-581
    • Axiotis, C.A.1    Guarch, R.2    Merino, M.J.3    Laporte, N.4    Neumann, R.D.5
  • 28
    • 0029154712 scopus 로고
    • Esterification of plasma membrane cholesterol and triacylglycerol-rich lipoprotein secretion in CaCo-2 cells: Possible rote of P-glyccprotein
    • Fidd FJ, Bom ER, Chen H, Munhy S, Mathur SN: Esterification of plasma membrane cholesterol and triacylglycerol-rich lipoprotein secretion in CaCo-2 cells: Possible rote of P-glyccprotein. J Lipid Res 1995;36:1533-1543.
    • (1995) J Lipid Res , vol.36 , pp. 1533-1543
    • Fidd, F.J.1    Bom, E.R.2    Chen, H.3    Munhy, S.4    Mathur, S.N.5
  • 29
    • 0029945113 scopus 로고    scopus 로고
    • What have we learnt thus far from mice with disrupted P-glycoprotein genes?
    • Borst P, Schinkel AH: What have we learnt thus far from mice with disrupted P-glycoprotein genes? Eur J Cancer [A] 1996;32:985-990.
    • (1996) Eur J Cancer [A] , vol.32 , pp. 985-990
    • Borst, P.1    Schinkel, A.H.2
  • 30
    • 0028920219 scopus 로고
    • Interaction of the P-glycoprotein multidrug transporter with peptides and ionophores
    • Sharom FJ, DiDiodato G, Yu X, Ashbourne KJD: Interaction of the P-glycoprotein multidrug transporter with peptides and ionophores. J Biol Chem 1995;270:10334-10341.
    • (1995) J Biol Chem , vol.270 , pp. 10334-10341
    • Sharom, F.J.1    DiDiodato, G.2    Yu, X.3    Ashbourne, K.J.D.4
  • 31
    • 0027464223 scopus 로고
    • Diverse multidrug-resistancemodification agents inhibit cytolytic activity of natural killer cells
    • Chong ASF, Markham PN, Gebel HM, Bines SD, Coon JS: Diverse multidrug-resistancemodification agents inhibit cytolytic activity of natural killer cells. Cancer Immunol Immunother 1993;36:133-139.
    • (1993) Cancer Immunol Immunother , vol.36 , pp. 133-139
    • Chong, A.S.F.1    Markham, P.N.2    Gebel, H.M.3    Bines, S.D.4    Coon, J.S.5
  • 32
    • 0028543657 scopus 로고
    • Expression of the mdr 1 P-glycoprotein gene: A mechanism of escape from glucocorticoid-induced apoptosis
    • Gruol DJ, Bourgeois S: Expression of the mdr 1 P-glycoprotein gene: A mechanism of escape from glucocorticoid-induced apoptosis. Biochem Cell Biol 1994;72:561-571.
    • (1994) Biochem Cell Biol , vol.72 , pp. 561-571
    • Gruol, D.J.1    Bourgeois, S.2
  • 33
    • 0029968426 scopus 로고    scopus 로고
    • Resistance to apoptotic cell death in a drug resistant T-cell leukemia cell line
    • Geyp M, Ireland CM, Pittman SM: Resistance to apoptotic cell death in a drug resistant T-cell leukemia cell line. Leukemia 1996;10:447-455.
    • (1996) Leukemia , vol.10 , pp. 447-455
    • Geyp, M.1    Ireland, C.M.2    Pittman, S.M.3
  • 34
    • 0028289608 scopus 로고
    • Low external pH and osmotic shock increase the expression of human MDR protein
    • Wei LY, Roepe PD: Low external pH and osmotic shock increase the expression of human MDR protein. Biochemistry 1994;33:7229-7238.
    • (1994) Biochemistry , vol.33 , pp. 7229-7238
    • Wei, L.Y.1    Roepe, P.D.2
  • 35
    • 0028914113 scopus 로고
    • P-glycoprotein and cell volume-activated chloride channels
    • Higgins CF: P-glycoprotein and cell volume-activated chloride channels. J Bioenerg Biomembr 1995;27:63-70.
    • (1995) J Bioenerg Biomembr , vol.27 , pp. 63-70
    • Higgins, C.F.1
  • 36
    • 0029081154 scopus 로고
    • Characterization of prenylcysteines that interact with P-glycoprotein and inhibit drug transport in tumour cells
    • Zhang L, Sachs CW, Fu HW, Fine RL, Casey PJ: Characterization of prenylcysteines that interact with P-glycoprotein and inhibit drug transport in tumour cells. J Biol Chem 1995;270:22859-22865.
    • (1995) J Biol Chem , vol.270 , pp. 22859-22865
    • Zhang, L.1    Sachs, C.W.2    Fu, H.W.3    Fine, R.L.4    Casey, P.J.5
  • 37
    • 0029846815 scopus 로고    scopus 로고
    • Renal drug transport: A review
    • Bendayan R: Renal drug transport: A review: Pharmacotherapy 1996;16:971-985.
    • (1996) Pharmacotherapy , vol.16 , pp. 971-985
    • Bendayan, R.1
  • 38
    • 0028032185 scopus 로고
    • Expression and function of P-glycoprotein in human mesangial cells
    • Belloreuss E, Ernest S: Expression and function of P-glycoprotein in human mesangial cells. Am JPhysiol 1994;36:C1351-C1358.
    • (1994) Am JPhysiol , vol.36
    • Belloreuss, E.1    Ernest, S.2
  • 39
    • 0029892356 scopus 로고    scopus 로고
    • Xenobiotic transport differences in mouse mesangial cell clones expressing Mdr1 and Mdr3
    • Ernest S, Belloureuss E: Xenobiotic transport differences in mouse mesangial cell clones expressing Mdr1 and Mdr3. Am J Physiol 1996;39:C910-C919.
    • (1996) Am J Physiol , vol.39
    • Ernest, S.1    Belloureuss, E.2
  • 40
    • 0029806297 scopus 로고    scopus 로고
    • Chronic cyclosporine nephropathy: The Achilles heel of immunosuppressive therapy
    • Bennett WM, DeMattos A, Meyer MM, Andoh T, Barry JM: Chronic cyclosporine nephropathy: The Achilles heel of immunosuppressive therapy. Kidney Int 1996;50:1089-1100.
    • (1996) Kidney Int , vol.50 , pp. 1089-1100
    • Bennett, W.M.1    DeMattos, A.2    Meyer, M.M.3    Andoh, T.4    Barry, J.M.5
  • 41
    • 0030213563 scopus 로고    scopus 로고
    • Expression patterns of multidrug-resistance (MDR1), multidrug resistance-associated protein (MRP), glutathione-S-transferase π (GST-π) and DNA topoisomerase II (TOPO II) genes in renal cell carcinomas and normal kidney
    • Kim WJ, Kaheki Y, Kinoshita H, Arao S, Fukumoto M, Yoshida O: Expression patterns of multidrug-resistance (MDR1), multidrug resistance-associated protein (MRP), glutathione-S-transferase π (GST-π) and DNA topoisomerase II (TOPO II) genes in renal cell carcinomas and normal kidney. J Urol 1996;156:506-511.
    • (1996) J Urol , vol.156 , pp. 506-511
    • Kim, W.J.1    Kaheki, Y.2    Kinoshita, H.3    Arao, S.4    Fukumoto, M.5    Yoshida, O.6
  • 42
    • 0029938602 scopus 로고    scopus 로고
    • Cyclosporine A treatment induces overexpression of P-glycoprotein in the kidney and other tissues
    • Jette L, Beaulieu E, Leclerc JM, Beliveau R: Cyclosporine A treatment induces overexpression of P-glycoprotein in the kidney and other tissues. Am J Physiol 1996;39:F756-F765.
    • (1996) Am J Physiol , vol.39
    • Jette, L.1    Beaulieu, E.2    Leclerc, J.M.3    Beliveau, R.4
  • 43
    • 27244461958 scopus 로고
    • P-glycoprotein mediated secretion of a fluorescent cyclosporine analog by teleost renal proximal tubules
    • Schramm U, Fricker G, Wenger R, Miller DS: P-glycoprotein mediated secretion of a fluorescent cyclosporine analog by teleost renal proximal tubules. Am J Physiol 1995;37:F46-F52.
    • (1995) Am J Physiol , vol.37
    • Schramm, U.1    Fricker, G.2    Wenger, R.3    Miller, D.S.4
  • 45
    • 0027732538 scopus 로고
    • Proteins regulating Ras and its relatives
    • Boguski MS, McCormick F: Proteins regulating Ras and its relatives. Nature 1993;366:643-654.
    • (1993) Nature , vol.366 , pp. 643-654
    • Boguski, M.S.1    McCormick, F.2
  • 46
    • 0026555717 scopus 로고
    • Modulation of activity of the promoter of the human mdr1 gene by ras and p53
    • Chin KV, Ueda K, Pastan I, Gottesman MM: Modulation of activity of the promoter of the human mdr1 gene by ras and p53. Science 1992;255:459-462.
    • (1992) Science , vol.255 , pp. 459-462
    • Chin, K.V.1    Ueda, K.2    Pastan, I.3    Gottesman, M.M.4
  • 47
    • 0028069634 scopus 로고
    • Loss of glomerular function and tubulointerstitial fibrosis: Cause or effect?
    • Ong ACM, Fine LG: Loss of glomerular function and tubulointerstitial fibrosis: Cause or effect? Kidney Int 1994;45:345-351.
    • (1994) Kidney Int , vol.45 , pp. 345-351
    • Ong, A.C.M.1    Fine, L.G.2
  • 48
  • 49
    • 0029079060 scopus 로고
    • Combined antagonism of endothelin A/B receptors links endothelin to vasoconstriction whereas angiotensin II effects fibrosis: Studies in chronic nephrotoxicity-in rats
    • Kon V, Hunley TE, Fogo A: Combined antagonism of endothelin A/B receptors links endothelin to vasoconstriction whereas angiotensin II effects fibrosis: Studies in chronic nephrotoxicity-in rats. Transplantation 1995;60:89-95.
    • (1995) Transplantation , vol.60 , pp. 89-95
    • Kon, V.1    Hunley, T.E.2    Fogo, A.3
  • 50
    • 0029591906 scopus 로고
    • FK506 nephrotoxicity: Morphologic and physiological characterization of a rat model
    • Stillamn IE, Andoh TF, Burdmann EA, Bennett WM, Rosen S: FK506 nephrotoxicity: Morphologic and physiological characterization of a rat model. Lab Invest 1995;73:794-803.
    • (1995) Lab Invest , vol.73 , pp. 794-803
    • Stillamn, I.E.1    Andoh, T.F.2    Burdmann, E.A.3    Bennett, W.M.4    Rosen, S.5
  • 51
    • 6844228963 scopus 로고
    • Angiotensin-II induces Ras activation via At1 receptors in vascular smooth muscle cells
    • Okuda M, Kawahara Y, Nakayama I, Okamoto Y: Angiotensin-II induces Ras activation via At1 receptors in vascular smooth muscle cells (abstract). Circulation 1995;92:821.
    • (1995) Circulation , vol.92 , pp. 821
    • Okuda, M.1    Kawahara, Y.2    Nakayama, I.3    Okamoto, Y.4
  • 52
    • 0029786877 scopus 로고    scopus 로고
    • Angioteasin-II type-1 receptor signals through raf-1 by a protein kinase C-dependent, ras-independent mechanism
    • Arai H, Escobedo JA: Angioteasin-II type-1 receptor signals through raf-1 by a protein kinase C-dependent, ras-independent mechanism. Mol Pharmacol 1996;50:522-528.
    • (1996) Mol Pharmacol , vol.50 , pp. 522-528
    • Arai, H.1    Escobedo, J.A.2
  • 55
    • 0029670142 scopus 로고    scopus 로고
    • A role for activated P21 (Ras) in inhibition regulation of platelet-derived growth factor (PDGF) type-beta receptor activation
    • Zubiaur M, Forman LW, Stice LL, Faller DV: A role for activated P21 (Ras) in inhibition regulation of platelet-derived growth factor (PDGF) type-beta receptor activation. Onccgene 1996;12:1213-1222.
    • (1996) Onccgene , vol.12 , pp. 1213-1222
    • Zubiaur, M.1    Forman, L.W.2    Stice, L.L.3    Faller, D.V.4
  • 56
    • 6844245787 scopus 로고
    • Pleiotropic effects of PDGF suggest new targets for cancer therapy
    • Deuel TF, Kim HRC: Pleiotropic effects of PDGF suggest new targets for cancer therapy. Antibody Immunoconjug Radiopharm 1995;8:333-340.
    • (1995) Antibody Immunoconjug Radiopharm , vol.8 , pp. 333-340
    • Deuel, T.F.1    Kim, H.R.C.2
  • 57
    • 0030030707 scopus 로고    scopus 로고
    • Ha-ras oncogene expression abrogates a pH-dependent endonuclease activity of apoptosis in normal rat kidney Cells
    • Ostad M, Shu WP, Kong L, Liu BCS: Ha-ras oncogene expression abrogates a pH-dependent endonuclease activity of apoptosis in normal rat kidney Cells. Cancer Lett 1996;98:175-182.
    • (1996) Cancer Lett , vol.98 , pp. 175-182
    • Ostad, M.1    Shu, W.P.2    Kong, L.3    Liu, B.C.S.4
  • 59
    • 0031034709 scopus 로고    scopus 로고
    • Lung resistance protein (LRP) expression in human normal tissues in comparison with that of MDR1 and MRP
    • Sugawara I, Akiyama S, Scheper RJ, Itoyama S: Lung resistance protein (LRP) expression in human normal tissues in comparison with that of MDR1 and MRP. Cancer Lett 1997;112:23-31.
    • (1997) Cancer Lett , vol.112 , pp. 23-31
    • Sugawara, I.1    Akiyama, S.2    Scheper, R.J.3    Itoyama, S.4


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